Skip to content
The Fascia Guide
SVEN

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
SortBy gradeBy yearA–Z
View
ListGrid
Showing 1,093–1,104 of 1,131 studies · page 92/95
  1. A++
    2003

    Prevalence of urinary and fecal incontinence and symptoms of genital prolapse in women

    Eva Uustal Fornell, Gun Wingren, Preben Kjølhede

    This questionnaire study investigated the links between urinary incontinence, fecal incontinence, and symptoms of genital prolapse in Swedish women. The researchers found that these three conditions often occur together…

    fecal incontinencegenital prolapseepidemiologydetrusor instabilityfemale urinary incontinence
  2. A
    2002

    Evidence of Connective Tissue Involvement in Acupuncture

    Helene M Langevin, David L Churchill, Junru Wu, Gary J Badger, Jason A Yandow, James R Fox, Martin H Krag

    Researchers investigated the "needle grasp" phenomenon in acupuncture, where it becomes harder to pull a needle out after manipulation. They hypothesized this is caused by connective tissue winding around the needle, ra…

    mechanical stressSubcutaneous tissueultrasound.Biomechanicshistology
  3. B
    2002

    Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

    Christian Termeer, Frauke Benedix, Jonathon Sleeman, Christina Fieber, Ursula Voith, Thomas Ahrens, Kensuke Miyake, Mar…

    During inflammation, components of our connective tissue like hyaluronic acid (HA) can break down. This study investigated how small fragments of HA affect the immune system. Researchers found that these fragments activ…

    hyaluronanextracellular matrixtoll-like receptorsglycosaminoglycansdendritic cells
  4. C
    2002

    Age-related Changes in the Collagen Network and Toughness of Bone

    X Wang, X Shen, X Li, C Mauli Agrawal

    This study investigated how the collagen network in bone tissue changes with age and how this affects bone toughness. Researchers analyzed 30 femurs from human cadavers, with donors ranging from 19 to 89 years of age. T…

    collagenAgingBoneToughnessDenaturation
  5. A
    2002

    Relationship of Acupuncture Points and Meridians to Connective Tissue Planes

    Helene M Langevin, Jason A Yandow

    Researchers investigated the hypothesis that the network of acupuncture points and meridians could represent the body's network of interstitial connective tissue. By mapping points in anatomical cross-sections of a huma…

    acupuncture; meridians; connective tissue; anatomy; fascia; signal transduction
  6. B
    2002

    Mammalian Hyaluronan Synthases

    Naoki Itano, Koji Kimata

    This 2002 review article describes the three enzymes that produce hyaluronan (HA) in mammals: HAS1, HAS2, and HAS3. These three enzyme isoforms have different characteristics and create different sizes of HA molecules.…

    hyaluronanBiosynthesisglycosyltransferasesynthasesHAS isoforms
  7. A++
    2002

    Effects of Biomechanical Stress on Bones in Animals

    D B Burr, A G Robling, C H Turner

    This animal study investigated how bones adapt to mechanical stress. The researchers found that cyclic loading, like in exercise, creates fluid flow within the bone that signals it to adapt. The rate of this loading is…

    Exercise; Mechanotransduction; Sensitivity; Saturation; Adaptation
  8. A
    2002

    Detection of changes in cartilage water content using MRI T2-mapping in vivo

    C Liess, S Lüsse, N Karger, M Heller, C-C Glüer

    Early-stage osteoarthritis (OA) is characterized by an elevated water content in cartilage. This study investigated if a specific MRI technique, T2-mapping, could detect these changes in living subjects. Healthy volunte…

    MRIEarly osteoarthritisWater contentT2-mapping
  9. A
    2002

    Adhesive capsulitis: role of MR imaging in differential diagnosis

    David Connell, Ravi Padmanabhan, Rachelle Buchbinder

    This study investigated whether magnetic resonance imaging (MRI) can identify the changes typical of adhesive capsulitis (frozen shoulder). Researchers compared MRI scans from 24 patients with clinical evidence of froze…

    frozen shoulderAdhesive capsulitisMR imagingArthroscopy
  10. 1A+
    2001

    Hyaluronan and its catabolic products in tissue injury and repair

    P W Noble

    This narrative review explores the role of hyaluronan (HA), a common component of connective tissue, in the body's response to injury. In healthy tissues, HA exists as a large molecule that helps maintain structural int…

    hyaluronaninflammationCD44respons to injury
  11. A
    2001

    Hyaluronan and Homeostasis: A Balancing Act

    M I Tammi, A J Day, E A Turley

    As only the title of this paper is available, it has not yet been summarized. The title suggests the article discusses the role of hyaluronan in maintaining homeostasis, the body's state of physiological balance. This i…

    hyaluronan homeostasis
  12. C
    2001

    Collagen accumulation in muscles of children with cerebral palsy and correlation with severity of spasticity

    Booth, Cortina-Borja, Theologis

    This study investigated the link between connective tissue and muscle function in children with cerebral palsy (CP). Researchers analyzed muscle samples from 26 children, comparing collagen content to clinical measures…

    Cerebral palsycollagenspasticity