Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2010
3D reconstruction of the crural and thoracolumbar fasciae
L Benetazzo, A Bizzego, R De Caro, G Frigo, D Guidolin, Carla SteccoResearchers created detailed 3D computer models to visualize the structure of the crural fascia in the lower leg and the superficial layer of the thoracolumbar fascia in the lower back. They found the crural fascia is c…
Connective tissuecollagenThoracolumbar fasciacrural fascia3D models - A2019
3D volumetric MR arthrographic assessment of shoulder joint capacity in patients with primary adhesive capsulitis
Hayri Ogul, Nurmuhammet Tas, Kutsi Tuncer, Gokhan Polat, Yasemin Ogul, Berhan Pirimoglu, Mecit KantarciThis study used 3D MR arthrography to measure and compare shoulder joint volume in patients with primary adhesive capsulitis (frozen shoulder) against a healthy control group. Researchers found that the patient group ha…
frozen shoulderAdhesive capsulitisMR arthrography - A++2019
8 natural supplements to help fight inflammation
Zawn VillinesInflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…
inflammationomega-3curcumin - A+++2020
A Closer Look at Anandamide Interaction With TRPV1
Chante Muller, Diane L Lynch, Dow P Hurst, Patricia H ReggioThis study used advanced molecular dynamics simulations to investigate how anandamide, an endocannabinoid, interacts with the TRPV1 ion channel, which is central to pain perception. The researchers observed that anandam…
TRP channels; TRPV1; anandamide; cannabinoids; molecular dynamics - A+++2021
A Closer Look at the Cellular and Molecular Components of the Deep/Muscular Fasciae
Caterina Fede, Carmelo Pirri, Chenglei Fan, Lucia Petrelli, Diego Guidolin, Raffaele De Caro, Carla SteccoThis narrative review describes fascia as a complex and dynamic connective tissue network. This network is composed of different cell types, an extracellular matrix, and nerve fibers. Each component plays a specific rol…
fascia; cells; extracellular matrix; nerve - A++2019
A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
Liane Bolke, Gerrit Schlippe, Joachim Gerß, Werner VossThis randomized, placebo-controlled study investigated the effects of a drinkable nutraceutical containing 2.5g of collagen peptides, vitamins, and minerals on skin health in women aged 35 and older. Over twelve weeks,…
aging; beauty; bioavailability; collagen peptides; corneometry; cutometry; high coverage [HC] collagen complex; wrinkles - A+++2019
A comparative multi-site and whole-body assessment of fascia in the horse and dog: a detailed histological investigation
Waqas Ahmed, Marta Kulikowska, Trine Ahlmann, Lise C Berg, Adrian P Harrison, Vibeke Sødring ElbrøndThis animal study compared the microscopic structure of fascia in horses and dogs across multiple body regions. Researchers found that horse fascia is generally tight and dense, while dog fascia is looser and more simil…
deep fascia; dog; histology; horse; hypodermis; myofascial kinetic lines; superficial fascia. - A++2017
A Curious Oversight in Acupuncture Research
Fletcher KovichIn this perspective article, the author argues that current acupuncture hypotheses overlook a crucial factor: the speed at which the treatment takes effect. Observations suggest that communication between acupoints and…
acupunctureelectrical wavesemiconductionsignal propagation - A2014
A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function
Katerina Nikolovska, Jana K Renke, Oliver Jungmann, Kay Grobe, Renato V Iozzo, Alina D Zamfir, Daniela G SeidlerThis study in mice investigated how the absence of a proteoglycan called decorin affects skin structure and function. Researchers found that mice lacking decorin had an altered composition of other sugar molecules (chon…
extracellular matrixDecorinSLRPDermatan sulfateFibroblast growth factor - A+++2016
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
In Young Choi, Laura Piccio, Patra Childress, Bryan Bollman, Arko Ghosh, Sebastian Brandhorst, Jorge Suarez, Andreas Mi…This study investigates how a periodic fasting-mimicking diet (FMD) affects symptoms of multiple sclerosis (MS) using mouse models and preliminary human trials. In animal models, the diet reduced inflammation and promot…
Fasting-mimicking diet; Intermittent fasting; Time-restricted eating; autoimmunity; multiple sclerosis - A+++2007
A driving force for change: interstitial flow as a morphoregulator
Joseph M Rutkowski, Melody A SwartzThis narrative review explores how the slow movement of fluid through the extracellular matrix, known as interstitial flow, acts as a crucial regulator of cell behavior and tissue structure. Driven by pressure gradients…
Morphologyinterstitial flow - A2016
A five year follow-up of women with obstetric anal sphincter rupture at their first delivery
Sidsel Linneberg, Stine Leenskjold, Karin GlavindThis study followed 82 women for five years after they experienced an obstetric anal sphincter rupture (OASR) during their first delivery. Researchers investigated long-term outcomes like incontinence and sexual functio…
urinary incontinenceanal incontinenceObstetric anal sphincter ruptureSexual dysfunctionValidated questionnaires