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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1,117–1,128 of 1,131 studies · page 94/95
  1. A++
    1996

    Clinical consequences of anal sphincter rupture during vaginal delivery

    E K Fornell, G Berg, O Hallböök, L S Matthiesen, R Sjödahl

    This study investigated the incidence and consequences of anal sphincter tears during childbirth. Researchers followed 51 women with a diagnosed tear and 31 women without one for six months after delivery. They found th…

    anal sphincter injury; incontinence; anal pressure
  2. A
    1996

    Effects of continuous and Intermittent forces on human fibroblasts in vitro

    Aldo Carano, Giuseppe Siciliani

    This in vitro study investigated how human connective tissue cells (fibroblasts) respond to different types of mechanical force. Researchers grew fibroblasts on flexible membranes and subjected them to either continuous…

    fibroblasttissue remodelingmechanical load
  3. B
    1996

    Selective regulation of myofiber differentiation by energy status during postnatal development

    Adrian P Harrison, A M Rowlerson, M J Dauncey

    In this animal study, researchers investigated how energy intake and environmental temperature affect muscle development in young pigs. The pigs were divided into groups that received either a high or low energy intake…

    skeletal muscledifferentiationmyosin isoformsnutritiontemperature
  4. A
    1994

    Triggerband technique

    Stephen Typaldos

    The Triggerband Technique is a manual therapy approach for treating musculoskeletal pain and dysfunction. It is based on the idea that distorted or injured fascial bands are the cause of many types of physical discomfor…

    fasciaefrozen shoulderfascial distortion modelTriggerbandTriggerpoint
  5. A
    1994

    Glutathione-Ascorbic Acid Antioxidant System in Animals

    Alton Meister

    This 1994 publication by Alton Meister discusses the biochemical interaction between glutathione and ascorbic acid (Vitamin C) within animal antioxidant systems. As the source material is limited to the title, the summa…

    Vitamin CAscorbic acidantioxidantanimals
  6. A
    1993

    Anal-sphincter disruption during vaginal delivery

    A H Sultan, M A Kamm, C N Hudson, J M Thomas, C I Bartram

    Researchers investigated how often hidden (occult) damage to the anal sphincter occurs during vaginal childbirth and how it affects bowel control. They studied over 200 women before and after delivery using ultrasound a…

    fecal incontinencevaginal deliveryanal-sphincter disruptionchildbirth
  7. A
    1993

    Angiogenic oligosaccharides of hyaluronan enhance the production of collagens by endothelial cells

    P Rooney, M Wang, P Kumar, S Kumar

    This study investigated how small fragments of hyaluronan (HA) affect collagen production during the formation of new blood vessels, a process called angiogenesis. Researchers observed that applying these HA fragments t…

    hyaluronancollagenAngiogenesis
  8. A++
    1990

    Immunological evidence for the accumulation of lipoprotein(a) in the atherosclerotic lesion of the hypoascorbemic guinea pig

    M Rath, L Pauling

    This animal study investigated the link between vitamin C, a specific cholesterol particle called Lipoprotein(a) or Lp(a), and atherosclerosis. Researchers found that guinea pigs, which like humans cannot produce their…

    Vitamin CAscorbic acidAtherosclerosis
  9. A
    1987

    Endothelial Growth Factors and Extracellular Matrix Regulate Dna Synthesis Through Modulation of Cell and Nuclear Expansion

    Donald E Ingber, Joseph A Madri,, Judah Folkman

    This study investigated how the extracellular matrix (ECM) and growth factors work together to regulate the growth of capillary endothelial cells, which line blood vessels. Researchers found that these cells needed both…

    extracellular matrixgrowth factorsnuclear modulationcell modulation
  10. A+++
    1984

    Structure and Properties of Ground Substances

    James Oschman

    This 1984 review outlines the structure of the body's 'ground substance,' the matrix found both within and between our cells. The author describes how this substance is composed of different biopolymers in the extracell…

    extracellular matrixcytoskeletonground substansaminoglycans
  11. A
    1979

    THE INFLUENCE OF MECHANICAL FORCES ON THE GLYCOSAMINOGLYCAN CONTENT OF THE RABBIT FLEXOR DIGITORUM PROFUNDUS TENDON

    GERALD C GILLARD, HELEN C REILLY, PAUL G BELL-BOOTH, MICHAEL H FLINT

    In this animal study on rabbits, researchers surgically altered the mechanical forces on a deep finger flexor tendon to observe how the tissue adapted. They analyzed how the content of glycosaminoglycans (GAGs)—molecule…

    collagenLoadingECMGAGdeep digital flexor tendon
  12. A++
    1978

    Ascorbic acid status in idiopathic hemochromatosis

    P Brissot, Y Deugnier, A Le Treut, F Regnouard, M Simon, M Bourel

    This study investigated Vitamin C (ascorbic acid) levels in patients with idiopathic hemochromatosis, a condition characterized by excessive iron accumulation. The results showed that untreated patients had significantl…

    Vitamin Ciron overloadHemochromatosis