Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2003
Effects of insulin lispro and chronic vitamin C therapy on postprandial lipaemia, oxidative stress and endothelial function in patients with type 2 diabetes mellitus
M Evans, R A Anderson, J C Smith, N Khan, J M Graham, A W Thomas, K Morris, D Deely, M P Frenneaux, J S Davies, A ReesPeople with type 2 diabetes often experience impaired blood vessel function and high levels of fat in their blood after eating, which are risk factors for cardiovascular disease. This study investigated whether insulin…
Oxidative stressendotheliumdiabetesinsulinpost-prandial lipaemia. - A2003
The myofibroblast in wound healing and fibrocontractive diseases
G GabbianiDuring wound healing, cells called fibroblasts can transform into a more specialized type called myofibroblasts. These myofibroblasts have contractile properties, much like muscle cells, which help to pull the edges of…
inflammationα-smooth muscle actinstress fibresTGF-β1 fibronectintension - A2003
Biophoton emission of human body
S Cohen, F A PoppResearchers measured the very faint light, or "biophotons," emitted by the human body using a special photon detector. They found that these emissions are not random, but seem to reflect the body's left-right symmetry a…
BiophotonBiological regulationBiological rhythmsHuman body measurmentLeft right symmetry - A+2003
Stress shielding of patellar tendon: effect on small-diameter collagen fibrils in a rabbit model
Tokifumi Majima, Kazunori Yasuda, Takamasa Tsuchida, Kunio Tanaka, Kiyoshi Miyakawa, Akio Minami, Kozaburo HayashiIn this animal study, researchers investigated the effects of mechanical unloading, or "stress shielding," on the patellar tendon in rabbits. The scientists completely released the tendon from its normal stress for thre…
Stress shielding · Patellar tendon · Collagen fibril diameter · Ultrastructure - A2003
Vibrations and their Indication in Sport-Injuries
U G Randoll, F F HennigThis paper discusses the cell-biological basis of bodily function, which is relevant for understanding sports injuries. The authors emphasize that all cells in the body are embedded in the extracellular matrix, a fluid-…
Therapy / Vibrations - A2003
Fecal and urinary incontinence after vaginal delivery with anal sphincter disruption in an obstetrics unit in the United States
Dee E Fenner, Becky Genberg, Pavna Brahma, Lorri Marek, John O L DeLanceyThis study investigated the link between severe perineal tears during a first vaginal delivery and later incontinence issues. Researchers sent questionnaires about pelvic floor function to women six months after they ga…
urinary incontinenceanal incontinencevaginal deliveryperineal lacerations - A2003
Mechanobiology and diseases of mechanotransduction
Donald E IngberThis 2003 article argues that medicine often overlooks the physical and mechanical aspects of disease, focusing instead on genetics. The author reviews how physical forces and the extracellular matrix are vital for norm…
extracellular matrixcytoskeletonmechanotransductionIntegrinstissue engineering - A2003
Tensegrity II. How structural networks influence cellular information processing networks
Donald E IngberThis theoretical article, the second in a two-part series, explores how a cell's physical structure influences its internal signaling and behavior. It builds on the "tensegrity" model, which describes the cell's skeleto…
BioinformaticsmechanotransductionIntegrinsmechanobiologyBiocomplexity - A++2003
Left-right asymmetry of biophoton emission from hemiparesis patients
Hyun-Hee Jung, Won-Myung Woo, Joon-Mo Yang, Chunho Choi, Jonghan Lee, Gilwon Yoon, Jong S Yang, Sungmuk Lee, Kwang-Sup…This small study investigated biophoton emission, a type of ultra-weak light emitted by the body, from the hands of seven patients with hemiparesis (one-sided muscle weakness). Researchers observed a strong tendency for…
Biophoton asymmetryBiophoton emissionHemiparesis patient - A2003
New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences
H Wiig, K Rubin, R K ReedThis review challenges the traditional view of the interstitium as merely a passive fluid reservoir. The researchers present data suggesting that connective tissue cells and the extracellular matrix actively regulate in…
inflammationextracellular matrixInterstitial fluid volumeintegrins edema - 1A+2003
The Common Compensatory Pattern: Its Origin and Relationship to the Postural Model
Ross E PopeAs only the title of this paper is available, we cannot summarize its contents in detail. The title suggests the article explores a concept known as the 'Common Compensatory Pattern'. The author likely discusses the ori…
fasciaCompensatory patternposture - A2003
Tensegrity I. Cell structure and hierarchical systems biology
Donald E IngberThis review article revisits the concept of tensegrity, a structural model for living cells first described a decade prior. The tensegrity model helps explain how cells control their shape, movement, and internal mechan…
cytoskeletonIntegrinscell mechanicsmicrotubulesMicrofilaments