Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2005
Deleterious effects of omitting breakfast on insulin sensitivity and fasting lipid profiles in healthy lean women
Hamid R Farshchi, Moira A Taylor, Ian A MacdonaldThis randomized crossover trial investigated how breakfast habits affect metabolism in healthy, lean women over two-week periods. The results suggest that omitting breakfast led to impaired insulin sensitivity and highe…
omitting breakfastinsulin sensitivity - A2005
A stromal address code defined by fibroblasts
G Parsonage, A D Filer, O Haworth, G B Nash, G E Rainger, M Salmon, C D BuckleyThis 2005 review article explores how immune cells (leukocytes) navigate within the body's tissues. The authors propose that fibroblasts create a "stromal address code" that acts as a local guidance system. This code di…
inflammationfibroblaststromal adress codeleukocyte - A2005
Cell–Matrix Entanglement and Mechanical Anchorage of Fibroblasts in Three-dimensional Collagen Matrices
H Jiang, F GrinnellResearchers studied how fibroblasts, a key connective tissue cell, behave within a three-dimensional collagen matrix that mimics body tissues. They found the cells' ability to engulf particles (phagocytosis) was reduced…
fibroblastcollagen matrixcell-matrix addesion - A++2005
Vitamin D
Adriana S Dusso, Alex J Brown, Eduardo SlatopolskyThis narrative review summarizes research on vitamin D, which is well-known for its essential role in calcium balance and bone metabolism. However, research has revealed a wider range of actions, including influencing c…
vitamin D metabolism; vitamin D receptor; calcium homeostasis; transcriptional regulation; rapid steroid actions - A+2005
Nutraceutical Therapies for Degenerative Joint Diseases: A Critical Review
ROBERT GOGGS, ANNE VAUGHAN-THOMAS, PETER D CLEGG, STUART D CARTER, JOHN F INNES, ALI MOBASHERI, MEHDI SHAKIBAEI, WOLFGA…This 2005 critical review examines the role of nutrition in managing degenerative joint diseases like osteoarthritis. The authors suggest that while nutritional factors are crucial for cartilage health, dietary programs…
articular cartilagenutritionosteoarthritisnutraceuticalVitamin C - A+++2005
Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro
Chee Ping Ng, Boris Hinz, Melody A SwartzThis in vitro study examines how the movement of fluid through tissues, known as interstitial flow, influences connective tissue cells. The researchers found that even low levels of flow, similar to what occurs during s…
fluid flow - A++2005
Obstetric anal sphincter injury ten years after: subjective and objective long term effects
Eva Uustal Fornell, Leif Matthiesen, Rune Sjödahl, Göran BergThis prospective observational study followed women for ten years to evaluate the long-term effects of obstetric anal sphincter injuries. Researchers found that anal function, particularly continence for gas and liquid…
anal sphincter injury; incontinence; anal pressure - A2005
Mechanical control of tissue growth: Function follows form
Donald E IngberThe full text of this 2005 article has not yet been summarized by our team. The title, "Mechanical control of tissue growth: Function follows form," suggests a focus on how mechanical forces influence the development an…
fasciamechanotransductionmorphogenesis - A2005
An Introduction to Human Biophoton Emission
Roeland Van Wijk, Eduard P A Van WijkThis narrative review explores biophoton emission, the ultraweak light naturally produced by all living systems, including the human body. The authors compiled and analyzed existing research, which has investigated how…
acupuncturebiophotonsSkinultraweak photon emissionconsciousness - A+2005
Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise
Benjamin F Miller, Jens L Olesen, Mette Hansen, Simon Dossing, Regina M Crameri, Rasmus J Welling, Henning Langberg, Al…Researchers investigated how strenuous exercise affects protein synthesis in both muscle and tendon. In this study, healthy young men performed one-legged kicking exercises, and biopsies were taken over the next 72 hour…
Muscletendonexercisecollegen syntes - A2004
Fibroblasts form a body-wide cellular network
Helene M Langevin, Carson J Cornbrooks, Douglas J TaatjesIn this mouse study, researchers investigated how cells called fibroblasts connect to one another within loose connective tissue. Using various microscopy techniques, they found that fibroblasts form an extensive, web-l…
Connective tissueSubcutaneous tissueConnexinGap junctionsCell signaling - B2004
Lactate metabolism: a new paradigm for the third millennium
L B GladdenFor a long time, lactate (often called lactic acid) was considered a metabolic waste product responsible for muscle fatigue. This 2004 review article describes a major shift in scientific understanding that began in the…
LactateglycolysisO2muscle fatigueanoxia
