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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1,069–1,080 of 1,131 studies · page 90/95
  1. A++
    2004

    Factors associated with pelvic floor dysfunction with emphasis on urinary and fecal incontinence and genital prolapse: an epidemiological study

    EVA UUSTAL FORNELL, GUN WINGREN, PREBEN KJØLHEDE

    This epidemiological study surveyed Swedish women aged 40 and 60 about pelvic floor dysfunction. The results indicate that urinary incontinence, fecal incontinence, and genital prolapse often occur together. Factors str…

    obesityanal sphincter ruptureurinary incontinence; fecal incontinence; genital prolapse; risk factors; epidemiology
  2. B
    2004

    Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts

    Jill E Kolodsick, Galen B Toews, Claudia Jakubzick, Cory Hogaboam, Thomas A Moore, Andrew McKenzie, Carol A Wilke, Cara…

    In this animal study, researchers investigated the drivers of lung fibrosis in mice. The team compared mice genetically deficient in the immune molecules IL-4, IL-13, or both. Results showed that mice lacking IL-13 were…

    fibroblastCell signalingcollagen synthesisalfa-SMA
  3. B
    2004

    Experimental approaches to hyaluronan structure

    Mary K Cowman, Shiro Matsuoka

    In this literature review, researchers summarize experimental studies on the structure of hyaluronan (HA). In conditions similar to the body (neutral, physiological salt solution), HA behaves as a long, semi-flexible po…

    hyaluronanviscosityPolysaccharidePolymer solutionOsmotic pressure
  4. A
    2004

    TGF-beta signaling and the fibrotic response

    Andrew Leask, David J Abraham

    This 2004 narrative review discusses the molecular basis of fibrotic diseases, which are characterized by excessive production and deposition of connective tissue. The authors summarize the state of knowledge concerning…

    sclerodermaCTGFSmadMAP kinaseprostacyclin
  5. A
    2004

    Consciousness and Quantum Information Processing: Uncovering the Foundation for a Medicine of Light

    Bruce D Curtis, J J Hurtak

    This theoretical paper suggests a deeper connection between consciousness, light, and the body's information systems. The authors discuss how biophotons (biological light) may play a role in the body's self-organization…

    biophotonsultraweak photons
  6. A
    2004

    Frozen Shoulder: MR Arthrographic Findings

    Bernard Mengiardi, Christian W. A. Pfirrmann, Christian Gerber, Jürg Hodler, Marco Zanetti

    Researchers used a specific type of MRI, an MR arthrogram, to identify the characteristics of frozen shoulder. They compared images from 22 patients with the condition to 22 healthy control subjects. The study found tha…

    frozen shoulderAdhesive capsulitisMR imagingArthroscopy
  7. A
    2004

    Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading

    MICHAEL KJÆR

    This review discusses how the extracellular matrix (ECM), particularly collagen, adapts to mechanical loading in tendons and muscles. Physical activity stimulates both the creation and breakdown of collagen, a process e…

    collagentendonsMechanical loadingECMskeletal muscles
  8. A++
    2004

    Biophotons, microtubules and CNS, is our brain a “Holographic computer”?

    F Grass, H Klima, S Kasper

    This theoretical article explores the idea that cells in the nervous system might communicate using light, specifically biophotons. The authors suggest that neurons have ideal characteristics for this, such as their str…

    biophotonsultraweak photons
  9. A
    2004

    Integrins in Mechanotransduction

    Akira Katsumi, A Wayne Orr, Eleni Tzima, Martin Alexander Schwartz

    This 2004 review article examines how cells sense and respond to physical forces, a process known as mechanotransduction. The authors focus on integrins, a class of proteins that anchor cells to their surroundings and a…

    mechanotransductionIntegrins
  10. C
    2004

    Myofascial Pain, Fibromyalgia or Fibrositis?

    J M S Pearce

    This critical analysis examines the diagnostic labels myofascial pain, fibromyalgia, and fibrositis. The author argues that these terms, often used for non-specific musculoskeletal pain, lack consistent physical or labo…

    Myofascial pain. FibromyalgiaFibrositisNociceptorCentral pain
  11. A++
    2003

    Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen

    Steffen Oesser, Jürgen Seifert

    This laboratory study investigated how degraded collagen affects cartilage cells. Researchers cultured chondrocytes from cows and added collagen hydrolysate (small collagen fragments) to their environment. They found th…

    Collagen hydrolysate; Collagen secretion; Chondrocyte metabolism; Type II collagen; Cell culture (Bovine)
  12. A
    2003

    Vitamin C, respiratory infections and the immune system

    Harri Hemilä

    This 2003 publication by Harri Hemilä explores the relationship between Vitamin C, respiratory infections, and immune system function. As only the title is available, specific conclusions regarding the study's exact res…

    Vitamin CAscorbic acid