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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
Showing 481–540 of 1,131 studies · page 9/19
  1. A+
    2018

    Anatomy of the Superficial Fascia System of the Breast: A Comprehensive Theory of Breast Fascial Anatomy

    Robert D Rehnke, Rachel M Groening, Eric R Van Buskirk, John M Clarke

    This study investigated the three-dimensional fascial structure of the breast through 12 cadaver dissections and clinical observations during surgery. The researchers identified a closed system of fascia and fat that su…

    superficial fasciabreastreconstructive breast surgerycosmetic breast surgery
  2. A++
    2018

    Release of fascial compartment boundaries reduces muscle force output

    Roy J Ruttiman, David A Sleboda,, Thomas J Roberts

    In this animal study, researchers investigated how the fascial sheets that enclose muscles affect their function. They surgically removed the fascia from a wing muscle in wild turkeys to see how it changed the muscle's…

    Muscletendoncompartmentfasciotomyintramuscular pressure
  3. A
    2018

    The influence of breathing on the central nervous system

    Bruno Bordoni, Shahin Purgol, Annalisa Bizzarri, Maddalena Modica, Bruno Morabito

    This narrative review explores the diaphragm's extensive influence on the central nervous system. The authors discuss how the rhythm of our breath can physically move the brain, alter patterns of neural oscillation, and…

    diaphragmbreathingphrenic nervevagus nerveneural oscillation
  4. A
    2018

    Neuroinflammation and central sensitization in chronic and widespread pain

    Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William Maixner

    Chronic pain is partly maintained by central sensitization, a state where the nervous system becomes hypersensitive. This review discusses how neuroinflammation—inflammation in the nervous system—contributes to this pro…

    inflammationchronic paainneuroinflammationsensitization
  5. A
    2018

    The anatomical relationships of the tongue with the body system

    Bruno Bordoni, Bruno Morabito, Roberto Mitrano, Marta Simonelli, Anastasia Toccafondi

    In this review article, the authors examine the tongue's functions and its anatomical connections to the rest of the body. The tongue is not only essential for swallowing, breathing, and speaking, but it also affects po…

    fasciadiaphragmphysiotherapytonguespeech therapy
  6. A
    2018

    Frontiers in fascia research

    Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…

    This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…

    fasciaultrasound.Pain therapySport sciencesIndentometry
  7. C
    2017

    Hypermobile Ehlers–Danlos Syndrome (a.k.a. Ehlers–Danlos Syndrome Type III and Ehlers–Danlos Syndrome Hypermobility Type): Clinical Description and Natural History

    Brad Tinkle, Marco Castori, Britta Berglund, Helen Cohen, Rodney Grahame, Hanadi Kazkaz, Howard Levy

    This 2017 review summarizes the clinical understanding of hypermobile Ehlers-Danlos syndrome (hEDS), thought to be the most common hereditary disorder of connective tissue. It is primarily characterized by musculoskelet…

    joint hypermobilityjoint hypermobility syndromeEhlers–Danlos syndrome type IIEhlers–Danlos syndrome hypermobility type
  8. C
    2017

    Concurrent validity of pain scales in individuals with myofascial pain and fibromyalgia

    Scott W Cheatham, Morey J Kolber, Monique Mokha, William J Hanney

    Researchers investigated the reliability of two common tools for measuring pain: the Numeric Pain Rating Scale (NPRS), where patients rate pain from 0 to 10, and the Visual Analog Scale (VAS). The study included 60 part…

    Myofascial painFibromyalgiapain scales
  9. B
    2017

    Acoustic wave therapy for cellulite, body shaping and fat reduction

    Doris Hexsel, Fernanda Oliveira Camozzato, Aline Flor Silva, Carolina Siega

    This study evaluated the efficacy of acoustic wave therapy (AWT) for cellulite and body shaping. Thirty women with moderate to severe cellulite underwent 12 treatment sessions on the glutes and thighs over six weeks. Th…

    Acoustic wave therapy; body shaping; cellulite; Cellulite Severity Scale; subcutaneous fat tissue thickness
  10. A+++
    2017

    Shielding of the geomagnetic field reduces hydrogen peroxide production in human neuroblastoma cell and inhibits the activity of CuZn superoxide dismutase

    Hai-Tao Zhang, Zi-Jian Zhang, Wei-Chuan Mo, Ping-Dong Hu, Hai-Min Ding, Ying Liu, Qian Hua, Rong-Qiao He

    This study investigates how an extremely weak magnetic field, similar to conditions in outer space or shielded environments on Earth, affects human cells. Researchers found that shielding the natural geomagnetic field r…

    hydrogen peroxide; hypomagnetic field; oxidative stress; reactive oxygen species; superoxide dismutase
  11. A
    2017

    CT arthrography of adhesive capsulitis of the shoulder: Are MR signs applicable?

    Milena Cernya, Patrick Omoumia, Ahmed Larbi, Daniel Manicourt, Anne Perozziello, Frédéric Lecouvet, Bruno Vande Berg, B…

    This retrospective study investigated whether signs of adhesive capsulitis (frozen shoulder) typically seen on MRI could also be identified using CT arthrography (CTA). Researchers compared CTA scans from 22 patients wi…

    frozen shoulderAdhesive capsulitisArthrographyRotator intervalCTA
  12. A+++
    2017

    Role of Magnesium in Vitamin D Activation and Function

    Anne Marie Uwitonze, Mohammed S Razzaque

    In this scientific review, the authors discuss how magnesium and vitamin D work together in the body. Magnesium acts as a cofactor, meaning it helps activate the enzymes that metabolize vitamin D in the liver and kidney…

    Vitamin D activationmagnesiumcalcidefiolcalcitriol
  13. B
    2017

    Mechanical Properties of the Cytoskeleton and Cells

    A F Pegoraro, P Janmey, D A Weitz

    In this review article, the authors describe the cytoskeleton, which is the cell's main mechanical structure. It is a complex and dynamic network of biopolymers that includes microtubules, actin, and intermediate filame…

    cytoskeletonmicrotubulesactin filamentintermediate filament
  14. A+
    2017

    Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials

    A W Ashor, A D Werner, J Lara, N D Willis, J C Mathers, M Siervo

    This systematic review and meta-analysis compiled data from 22 randomized controlled trials to assess the effect of vitamin C supplementation on glycemic control. Overall, the researchers found no significant effect on…

    Vitamin Cinsulin resistensglycaemic control
  15. B
    2017

    Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells

    Masahiro Ohgidani, Takahiro A Kato, Masako Hosoi, Makoto Tsuda, Kohei Hayakawa, Chie Hayaki, Rie Iwaki, Noriaki Sagata,…

    Researchers are investigating the role of brain immune cells called microglia in fibromyalgia. This study used a new technique to create microglia-like cells from the blood of people with fibromyalgia and healthy indivi…

    Fibromyalgiamikroglia
  16. A+++
    2017

    Early versus Delayed Rehabilitation after Acute Muscle Injury

    Monika L Bayer, Peter Magnusson, Michael Kjaer

    This research entry, titled "Early versus Delayed Rehabilitation after Acute Muscle Injury," is currently awaiting a detailed summary. The title suggests it explores the optimal timing for starting rehabilitation follow…

    Rehabilitationmuscle injurymechanical loading in rehabilitation
  17. B
    2017

    Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma

    Emmanuel Bäckryd, Lars Tanum, Anne-Li Lind, Anders Larsson, Torsten Gordh

    This study investigated signs of inflammation in people with fibromyalgia (FM). Researchers analyzed 92 different inflammation-related proteins in both blood plasma and cerebrospinal fluid from 40 FM patients, comparing…

    inflammationFibromyalgiacytokineschronic paincerebrospinal fluid
  18. A
    2017

    Non-contrast MRI diagnosis of adhesive capsulitis of the shoulder

    Andrew S Chi, John Kim, Suzanne S Long, William B Morrison, Adam C Zoga

    This study investigated whether a standard MRI without contrast dye could be used to reliably diagnose adhesive capsulitis, also known as frozen shoulder. Researchers reviewed MRIs for specific signs, such as a thickene…

    MRIfrozen shoulderAdhesive capsulitisNoncontrast
  19. A++
    2017

    Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study

    Paul E Marik, Vikramjit Khangoora, Racquel Rivera, Michael H Hooper, John Catravas

    In this retrospective before-after study, researchers investigated the effect of a combination therapy of intravenous vitamin C, hydrocortisone, and thiamine for patients with severe sepsis and septic shock. They compar…

    corticosteroid; hydrocortisone; septic shock; thiamine; vitamin C
  20. A+++
    2017

    Resveratrol regulates body weight in healthy and ovariectomized rats

    Rupali Sharma, Neel Kamal Sharma, M Thungapathra

    This animal study on rats investigated how the plant compound resveratrol affects body weight in both healthy subjects and those who had undergone ovariectomy, a model for menopause. The results suggest that resveratrol…

    OVX; Ovariectomy; Resveratrol; Soya free diet
  21. A
    2017

    Correlations of magnetic resonance imaging findings with clinical symptom severity and prognosis of frozen shoulder

    Jong Pil Yoon, Seok Won Chung, Byung Joo Lee, Hyung Sup Kim, Jae Hyuck Yi, Hyun‑Joo Lee, Won‑Ju Jeong, Sung Gyu Moon, K…

    Researchers used a specific type of MRI (indirect MR arthrography) to examine the shoulders of 52 people with frozen shoulder and 52 without. They found that certain features, like thickening and inflammation-related ch…

    frozen shoulderMR findingIndirect MR arthrogramClinical symptomCorrelation
  22. A
    2017

    Adhesive Capsulitis of the Shoulder Joint: Value of Glenohumeral Distance on Magnetic Resonance Arthrography

    Kyu Hong Lee, Hee Jin Park, So Yeon Lee, In Young Youn, Eugene Kim, Jai Hyung Park, Se Jin Park

    Researchers investigated a new way to help diagnose adhesive capsulitis (frozen shoulder) using a specific type of MRI called MR arthrography. They measured the distance between the ball and socket of the shoulder joint…

    Adhesive capsulitisMR imagingShoulderArthrography
  23. A+++
    2017

    Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats

    Victor Fabricio, Jorge Camargo Oishi, Bruna Gabriele Biffe, Leandro Dias Gonçalves Ruffoni, Karina Ana da Silva, Keico…

    This animal study on rats investigated how resveratrol affects blood pressure and vascular function during estrogen deficiency, mimicking post-menopausal conditions. Researchers found that a lack of estrogen led to high…

    blood pressureresveratrolPostmenopause
  24. A+++
    2017

    Proinflammatory Cytokines and Oxidative Stress Decrease the Transport of Dopamine Precursor Tyrosine in Human Fibroblasts

    Ravi Vumma, Jessica Johansson, Nikolaos Venizelos

    This laboratory study investigated how inflammation and oxidative stress affect the transport of the amino acid tyrosine in human fibroblasts, a type of connective tissue cell. Tyrosine is a crucial precursor for the ne…

    Dopamine precursor; Human fibroblasts; Neuropsychiatric disorders; Oxidative stress; Proinflammatory cytokines; Tyrosine transport.
  25. B
    2017

    The Application of Acoustic Myography in Canine Muscle Function and Performance Testing

    Christina Fenger, Adrian P Harrison

    This animal study on 11 Labrador dogs used acoustic myography (AMG) to measure muscle activity during walking and trotting. Researchers focused on two muscles, the m. gluteus superficialis and m. longissimus lumborum, t…

    Mechanomyographym.longissimusm.glutealDogMuscle contraction
  26. A++
    2017

    A New Definition of an Acupuncture Meridian

    Fletcher Kovich

    This perspective article proposes a new definition of acupuncture meridians, moving away from the idea of dedicated anatomical vessels. The author suggests that meridians are actually tracts of tissue that become affect…

    acupunctureelectrical wavesemiconductionsignal propagation
  27. A
    2017

    Does the vaginal wall become thinner as prolapse grade increases?

    Rhiannon Bray, Alex Derpapas, Ruwan Fernando, Vik Khullar, Demetri C Panayi

    This study investigated the relationship between vaginal wall thickness and the severity of pelvic organ prolapse. Researchers used ultrasound to measure the vaginal walls of 243 women with symptomatic prolapse. They fo…

    Prolapse . Ultrasonography . Vaginal wall thickness
  28. 1A+
    2017

    Emotions in Motion: Myofascial Interoception

    B Bordoni, F Marelli

    In this perspective piece, the authors argue that the myofascial system is closely linked to our emotional state. They suggest that manual treatment not only affects the body physically but also activates the interocept…

    fasciaManual TherapyMyofascialOsteopathicInteroception
  29. A++
    2017

    The effect of pre-exercise vibration stimulation on the exercise-induced muscle damage

    Ji-Yun Kim, Da-Haeng Kang, Joon-Hee Lee, Se-Min O, Jae-Keun Jeon

    This study investigated whether vibration stimulation before or after exercise could reduce exercise-induced muscle damage. Thirty healthy men were divided into three groups: one receiving vibration before exercise, one…

    pressure pain thresholdmuscle fatiguemuscle damage
  30. A+++
    2017

    Resveratrol supplementation reduces pain experience by postmenopausal women

    Rachel H X Wong, Hamish M Evans, Peter R C Howe

    This randomized, double-blind, placebo-controlled study investigated whether resveratrol supplementation could reduce pain and improve well-being in postmenopausal women. Over 14 weeks, participants taking 75 mg of resv…

    Resveratrolpolyphenolemenopause
  31. A+++
    2017

    Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study

    John F Pearson, Juliet M Pullar, Renee Wilson, Janet K Spittlehouse, Margreet C M Vissers, Paula M L Skidmore, Jinny Wi…

    This cohort study examined vitamin C status in 404 fifty-year-olds in New Zealand. Researchers measured the concentration of vitamin C in participants' blood plasma as well as their dietary intake. The results showed th…

    ascorbate; cognition; HbA1c; insulin; glucose; hypovitaminosis C
  32. A++
    2017

    EFFECT OF MATRIX RHYTHM THERAPY (MRT) COMBINED WITH PHYSIOTHERAPY INTERVENTION IN FROZEN SHOULDER – A CASE REPORT

    Vijay Bhartiya, Shrikant Darade, Sandip Bhagwat, Manjumala Roy

    This case report describes the treatment of a 52-year-old man with a painful and stiff right shoulder, diagnosed as frozen shoulder. His condition also involved tendinosis, bursitis, and osteoarthritic changes. The pati…

    exercisesfrozen shoulderMRT
  33. A+
    2017

    The nature and biology of basement membranes

    Ambra Pozzi, Peter D Yurchenco, Renato V Iozzo

    This review article discusses the nature and biology of basement membranes. These are thin, flexible sheets of tissue that line and separate different structures in the body. Once thought to be just passive scaffolding,…

    Collagen; laminin; heparan sulfate proteoglycan; discoidin domain receptor; integrin
  34. A++
    2017

    A Curious Oversight in Acupuncture Research

    Fletcher Kovich

    In this perspective article, the author argues that current acupuncture hypotheses overlook a crucial factor: the speed at which the treatment takes effect. Observations suggest that communication between acupoints and…

    acupunctureelectrical wavesemiconductionsignal propagation
  35. B
    2017

    Mechanical properties of a collagen fibril under simulated degradation

    David C Malaspinaa, Igal Szleifera, Yasin Dhahera

    This study used computer simulations to investigate how collagen fibrils lose their strength. Researchers modeled three different types of degradation: the removal of cross-links, surface damage, and damage throughout t…

    collagenMolecular dynamicsDegradationMMP
  36. A
    2017

    The second terminations of the suboccipital muscles: An assistant pivot for the To Be Named Ligament

    Xiao-Ying Yuan, Chan Li, Jia-Ying Sui, Qi-Qi Zhao, Xiao Zhang, Na-Na Mou, Zhao Huang-Fu, Okoye Chukwuemeka Samuel, Nan…

    In this anatomical dissection study of 35 head-neck specimens, researchers investigated small muscle attachments in the suboccipital region. The scientists confirmed the existence of "second terminations" from several s…

    Myodural Bridge
  37. A
    2017

    The universal existence of myodural bridge in mammals: an indication of a necessary function

    Nan Zheng, Xiao-Ying Yuan, Yan-Yan Chi, Pei Liu, Bing Wang, Jia-Ying Sui, Seung-Ho Han, Sheng-Bo Yu, Hong-Jin Sui

    The myodural bridge is a connective tissue structure linking one of the deep, upper neck muscles to the spinal dura mater. This anatomical study investigated whether this structure, known in humans, also exists in other…

    Myodural Bridge
  38. A
    2017

    The myodural bridge existing in the Nephocaena phocaenoides

    Pei Liu, Chan Li, Nan Zheng, Qiang Xu, Sheng-Bo Yu, Hong-Jin Sui

    The myodural bridge is a connection between a small neck muscle and the spinal cord's outer covering (the dura mater) previously identified in humans. In this anatomical animal study, researchers investigated whether a…

    dura materMyodural Bridge
  39. A
    2017

    What's in a name: Myofascial Release or Myofascial Induction?

    Leon Chaitow

    This commentary discusses two terms for a similar manual therapy technique: Myofascial Release (MFR) and Myofascial Induction Therapy (MIT). The author notes that while the techniques are virtually identical, the names…

    Myofascial releaseMyofascial Induction therapy
  40. A+++
    2017

    Therapeutic effectiveness of instrument-assisted soft tissue mobilization for soft tissue injury: mechanisms and practical application

    Jooyoung Kim, Dong Jun Sung, Joohyung Lee

    This narrative review explores the mechanisms and practical use of Instrument-Assisted Soft Tissue Mobilization (IASTM) for treating soft tissue injuries. IASTM involves using specialized tools to apply mechanical press…

    Injury; Instrument-assisted soft tissue mobilization; Pain; Range of motion; Soft tissue function.
  41. A
    2017

    Rectus Capitis Posterior Minor

    Gabriel Venne, Brian J Rasquinha, Manuela Kunz, Randy E Ellis

    This cadaver study investigated the connection between a small neck muscle (Rectus Capitis Posterior Minor, RCPMi) and the spinal dura mater. Researchers used both microscopic analysis and biomechanical testing to clari…

    biomechanical testingcervical dura matermechanical influence of musclesmechanical influence of soft tissuerectus capitis posterior minor
  42. A
    2017

    Implications of immune dysfunction on endometriosis associated infertility

    Jessica E Miller, Soo Hyun Ahn, Stephany P Monsanto, Kasra Khalaj, Madhuri Koti, Chandrakant Tayade

    This literature review explores the link between endometriosis and infertility, a common issue for which the cause is not fully understood. The authors suggest that dysfunction in the immune system plays a significant r…

    cytokines; endometriosis; infertility; inflammation; oxidative stress.
  43. A++
    2017

    Massage therapy research review

    Tiffany Field

    This review summarizes research showing beneficial effects of massage therapy for a wide range of conditions, including prenatal depression, pain syndromes, autoimmune conditions, and issues related to aging. The author…

    Massage therapy research review
  44. A
    2017

    The indeterminable resilience of the fascial system

    Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice Sacconi

    This commentary proposes a model of fascia not as layers, but as a network of polyhedral microvacuoles of connective tissue. These structures connect the body's systems and can change shape in response to tension, allow…

    fasciafibroblastManual TherapyOsteopathicfascial continuum
  45. A
    2017

    Molecular insights into prolyl and lysyl hydroxylation of fibrillar collagens in health and disease

    Rutger A F Gjaltema, Ruud A Bank

    This narrative review provides an updated overview of the complex process of creating mature collagen. The formation of collagen fibrils from precursor molecules involves many enzymes and chaperones in a series of steps…

    Bruck syndrome; Collagen; Ehlers–Danlos syndrome; connective tissue disorders; fibrosis; lysyl hydroxylation; osteogenesis imperfecta; prolyl hydroxylation.
  46. A
    2017

    Muscle strength and stiffness in resistance exercise: Force transmission in tissues

    Hans Chaudhry, Bruce Bukiet, Ellen Z Anderson, Jared Burch, Thomas Findley

    Researchers used a mathematical model to estimate how forces are transmitted through the quadriceps muscle during isometric resistance exercises. They specifically looked at how knee angle affects muscle stiffness, stre…

    Knee muscle strength; Stiffness; Mathematical modeling; Resistance exercise
  47. A+
    2017

    Oxidative Stress and Endometriosis: A Systematic Review of the Literature

    Gennaro Scutiero, Piergiorgio Iannone, Giulia Bernardi, Gloria Bonaccorsi, Savino Spadaro, Carlo Alberto Volta, Pantale…

    This systematic review explores the connection between oxidative stress and endometriosis, a condition where uterine-like tissue grows outside the uterus, causing pain and infertility. Oxidative stress is an imbalance b…

    Oxidative stressendometriosisROS
  48. A++
    2017

    Telocytes: Connective tissue repair and communication cells

    Leon Chaitow

    This commentary highlights a newly identified type of connective tissue cell called a telocyte. We already know that other cells, like fibroblasts, respond to mechanical forces from manual therapy, influencing tissue re…

    mechanotransductiontelocytesinterstitial cellsregeneration
  49. A
    2017

    The significance of closed kinematic chains to biological movement and dynamic stability

    Stephen Levin, Susan Lowell de Sol!orzano, Graham Scarr

    Biomechanical research has long focused on the body as a system of levers, but this review highlights the importance of "closed kinematic chains" (CKCs). These are continuous mechanical loops that couple multiple parts…

    biotensegrityBiomechanicsClosed-chainDevelopmentEvolution
  50. B
    2017

    Evaluation of fascial manipulation in carpal tunnel syndrome

    Marco Pintucci, Marta Imamura, Aurore Thibaut, Lucas M de Exel Nunes, Mylene Mayumi Nagato, Helena H Kaziyama, Satiko T…

    Details for this study are not yet available. The research, published in 2017, appears to evaluate the effectiveness of Fascial Manipulation® for treating carpal tunnel syndrome. Without an abstract, further details abo…

    Fascial manipulationcarpal tunnel syndrome
  51. A+
    2017

    Theoretical study of aerobic vitamin C loss kinetics during commercial heat preservation and storage

    Micha Peleg

    This theoretical study presents a mathematical model to describe how vitamin C is lost in food during commercial heat processing and storage. The model accounts for the degradation of two forms of the vitamin, ascorbic…

    Ascorbic acid; Degradation reactions; Dehydroascorbic acid; Kinetics; Storage; Thermal processing.
  52. A
    2017

    Amino acid composition in determination of collagen origin and assessment of physical factors effects

    Marlena Gauza-Włodarczyk, Leszek Kubisz, Dariusz Włodarczyk

    This study examines the amino acid composition of collagen derived from various sources, including fish skin, bovine Achilles tendon, and bone tissue. The researchers found that the levels of hydroxyproline, a unique am…

    hydroxyprolineBone collagenFish skin collagenIrradiationPolymer
  53. A
    2017

    Vitamin C for preventing atrial fibrillation in high risk patients: a systematic review and meta-analysis

    Harri Hemilä, Timo Suonsyrjä

    This systematic review and meta-analysis examined 15 trials to see if vitamin C could prevent atrial fibrillation in high-risk patients. The analysis, involving over 2000 subjects, found inconsistent results depending o…

    Ascorbic acidantioxidantArrhythmiaAtrial fibrillationCardiac surgery
  54. A+++
    2017

    Activation of type 2 cannabinoid receptor (CB2R) by selective agonists regulates the deposition and remodelling of the extracellular matrix

    Tao Guan, Guiyang Zhao, Honghui Duan, Yang Liu, Feng Zhao

    This in vitro study investigated how activating the type 2 cannabinoid receptor (CB2R) affects scar formation in eye connective tissue after surgery. Researchers found that human Tenon’s fibroblasts express these recept…

    Matrix metalloproteinase 1 (MMP-1); Tenon’s fibroblasts; Transforming growth factor-β1; Type 2 cannabinoid receptor (CB2R); Wound healing
  55. B
    2017

    Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis

    Hsin-Ying Huang, Ana Rivas-Caicedo, François Renevey, Hélène Cannelle, Elisa Peranzoni, Leonardo Scarpellino, Debbie L…

    This study investigated how antibody-producing plasma cells are supported within lymph nodes. Researchers identified a specific type of connective tissue cell, a medullary fibroblastic reticular cell (FRC), that forms a…

    FRC subsetslymph node medullaextrafollicular B cell differentiationplasma cell survivalhumoral response
  56. C
    2017

    S100A4 in cancer progression and metastasis: A systematic review

    Fei Fei, Jie Qu, Mingqing Zhang, Yuwei Li, Shiwu Zhang

    This systematic review examines the role of the protein S100A4 in cancer progression and metastasis. S100A4 is involved in the epithelial-mesenchymal transition, a key process that allows cancer cells to spread. The aut…

    metastasisS100A4malignant tumorepithelial-mesenchymal transition
  57. B
    2017

    All you need to know about the AIP diet

    Lana Burgess

    This article reviews the Autoimmune Protocol (AIP) diet, which aims to reduce inflammation and relieve symptoms of autoimmune disorders. The diet is based on the idea that problems with the gut wall, sometimes called 'l…

    inflammationAutoimmune protocolautoimmune disease
  58. C
    2017

    X-Rays Effects on Cytoskeleton Mechanics of Healthy and Tumor Cells

    Valeria Panzetta, Marta De Menna, Ida Musella, Mariagabriella Pugliese, Maria Quarto, Paolo A. Netti, Sabato Fusco

    This study investigated how X-ray radiation affects the internal structure, or cytoskeleton, of both healthy cells and tumor cells in a lab setting. Researchers exposed both cell types to different doses of radiation an…

    X-rays; Cytoskeleton; Mechanobiology; Focal Adhesion; Particle Tracking; Microrheology
  59. A++
    2017

    Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes

    Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M Shaw

    This study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…

    Vitamin CsepsisIntensive careHypovitaminosis CCritical illness
  60. A
    2017

    Reconnecting the Body in Eastern and Western Medicine

    Helene M Langevin, Rosa N Schnyer

    Details for this 2017 publication, titled 'Reconnecting the Body in Eastern and Western Medicine' by Helene M. Langevin and Rosa N. Schnyer, have not yet been summarized. The title suggests a discussion comparing and in…

    acupunctureTCM