Topics: Cannabinoids; anti-proliferative effects; apoptosis; cancer; cell proliferation; inflammation
Topics: Cannabis sativa; anandamide; breast cancer; cannabidiol; cannabidivarin; cannabigerol; cannabinoids; cannabinol; Δ9-tetrahydrocannabinol
Topics: cancer; cannabinoid receptor; cannabinoids; oncological diseases cancer treatment
Topics: Cannabinoids in dermatology; cannabidiol; cannabis; endocannabinoids.
Topics: Epigenetics; breast cancer; chromatin modification; flavonoids; methylation
Topics: cancer medicine; cannabinoid receptors; cannabinoids; immune medicine
Topics: plasma membrane, mechanotransduction, membrane tension, mechanosensor
2019: Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models
Topics: Platelet, platelet decoys, trombosis, metastatic tumors
2019: Hyaluronan: molecular size-dependent signaling and biological functions in inflammation and cancer
Topics: cancer; CD44; cell signaling; hyaluronan; inflammation; pharmacological targeting; RHAMM
2019; Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2
Topics: F-actin; HIF-1α; YAP1; hippo pathway; lamellipodia; metastasis; synaptopodin 2; triple-negative breast cancer; vitamin C.
2019; High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition
Topics: vitamin C, metastasis, TGF-!1, breast cancer
Topics: CBD; Cannabis sativa; THC; breast cancer; cannabidiol; cannabinoid receptor; delta-9-tetrahydrocannabinol
Topics: Stretching, Tumor growth, Breast cancer
2018: Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas
Topics: Hyaluronan synthase, Astrocytoma, Prognosis, Glioma, Hyaluronan
Topics: Ascorbic acid; Cancer treatment; Epigenetics; Hematological malignancies; Vitamin C
2018; Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C
Topics: Invasive cancer of the renal pelvis
Persistent EGFR signaling
Cell cycle deregulation
2018; Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer
Topics: cannabinoids, oxidative stress, iflammation, cancer
Topics: Vitamin C, ascorbate, cancer, pharmacokinetics
Topics: Spontaneous photon emission (SPE), Breast cancer, Preliminary screening, Cluster analysis, Oxidative metabolic, Reactive oxygen varieties (ROS)
Topics: S100A4, metastasis, malignant tumor, epithelial-mesenchymal transition
2017: Oscillations of ultra-weak photon emission from cancer and noncancer cells stressed by culture medium change and TNF-alfa
Topics: ultraweak photon emission, biophoton, cancer
2017: Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface
Topics: fascia, C-type lectin, tumor angiogenesis, extracellular matrix, endothelium, novel protein, vessel formation
Topics: extracellular matrix, tumor microenvironment, cell signaling
2016: Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs
Topics: Angiogenesis, apoptosis, cancer, collagen, metalloproteinase, metalloproteinase inhibitor, metastasis
Topics: Cancer, fascia, connective tissue, extracellular matrix
Topics: fascia, cancer, tumor invasion, extracellular matrix, microenvironment, cell migration
Topics: fascia, cancer biophysics, mitochondrial dysfunction, water ordering, microtubule oscillations, disturbed coherence, LDH virus
Topics: fascia, hyaluronan, breast cancer, inflammation, tumor micro environment, RHAMM/HMMR, CD44, macrophage
2014: Biotensegrity of the extracellular matrix: physiology, dynamic mechanical balance, and implications in oncology and mechanotherapy
Topics: fascia, biotensegrity, cancer, extracellular matrix, mechanotherapy, neuroblastoma
2013; Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin-C deficient mice
Topics: ascorbate, gulonolactone oxidase knockout mice, metastasis, tumor growth, melanoma B16F0, breast cancer 4T1, collagen I and IV, matrix metalloproteinase-9, apoptosis, interleukin-6
2012: Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity
Topics: fascia, lymph flow, microenvironment, mechanobiology, tumor cells, cancer, stiffness, TGF-beta,
2011: Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
Topics: fascia, cancer, tumor cells, fibrosis, extracellular matrix, stiffness
Topics: fascia, mechanical, extracellular matrix, stroma, cell traction, cytoskeleton, cancer therapy
2007; Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
Topics: ascorbic acid ” cancer ” vitamin C ” pharmacokinetics
2006: Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis
Topics: cell motility, EGF receptor, extracellular matrix, matrix metalloproteinase
Topics: mechanotransduction, cancer, extracellular matrix, cytoskeleton
1978; Supplemental ascorbate in the supportive treatment of cancer: Reevaluation of prolongation of survival times in terminal human cancer
Topics: vitamin C, ascorbate, cancer
One of the best ways to keep yourself healthy, free from pain and injuries is to take care of your Fascia. Here are 9 tips on how to take care of your Fascia.
On the Fascia Guide FAQ we have gathered the most common questions and answers about Fascia. Is there anything you would like to know? Visit the page and submit your question.
From Newton, to Einstein, to the new wildfire of Fascia Research. How do we understand things from a different perspective?
To truly understand Fascia, you must understand the whole. But how do you do that if you have trained all your life to divide and separate?
The concept of Fascia Lines is a great way to understand how the body functions and how treatment can be optimized to increase mobility and functionality. The main principle is that muscles, no matter what they do individually, also affect tissues throughout the entire body.
Tom Myers is perhaps best known for his book Anatomy Trains, where he describes the Myofascial lines which help us understand movement and functions of the body
Fascia research has sparked a wildfire of new insights that are challenging conventional belief about how the body works – and the latest insights are presented at the 2018 Fascia Research Congress in Berlin.
You probably know that the immune system is our defensive wall protecting us from the threats from the outside world – but do you know how it works and how to boost it?
In 2015 veterinary Vibeke S Elbrønd published the first report on Fascia and horses. To make that happen she had to learn all there was regarding fascia, she had to become a fascia expert.
At the 2015 Fascia Research Congress in Washington DC, Tom Myers, the author of Anatomy Trains, gives a short introduction to Fascia and how new research changes the way we look at pain and discomfort.
Strolling under the skin is a fascinating journey inside a living body. With small camcorders, Dr. Jean Claeude Guimberteau has managed to capture how Fasica actually looks in a living human body.
What is Fascia? New research shows that it is more than the layer around the muscles. It is a network without beginning or end, from the skin, through the entire body, to the smallest cell.
Exclusive interview with Dr Stephen Levin, the worlds leading expert on Biotensegrity, at the Fascia Research Congress 2015.
In 2015 veterinary Vibeke S Elbrønd published the first report on Fascia and horses. Through autopsy she found that the horse has the same kind of chains and networks of connective tissue through the body, as found in humans.
David Lesondak is a structural integrator and a myofascial specialist who has been working for many years trying to explain what fascia is, as well as the benefits you get from treating different problems with fascia treatment. In an interview at the Fascia Research Congress in Berlin 2018, he describes the basics of what fascia is and what challenges it is facing in the strive for recognition in the medical field.
Look at a ballet dancer, a gymnast or a drummer and study their movement, feeling, timing, it is easy to be fascinated by how fast it is. Fascia helps us understand how the body is able to function in such an incredible way.
New research leads to insights and by looking at the body in a completely new way we get new perspectives and explanations to symptoms and diseases. At the 2015 Joint Conference on Acupuncture, Oncology and Fascia in Boston, research was presented regarding Fascia and Cancer
By beginning to see the body as something that is alive, and not something that is dead, we have been able to begin to notice other things.
What do we know about the Fascias function and what affects the Fascias ability to rebuild – and how can we use that knowledge in our everyday lives?
Fascia is a network of connective tissue, without beginning and end, which encloses everything in the whole body, from muscles and bones, to organs and cells. But what does that mean?
New research shows that low back pain is caused by inflammation in the Fascia. But why are we getting low back pain and what happens in our body when we get back pain?
Here are three major reasons why the Fascia’s central importance to the body’s functionality is not nousehold knowledge. It might be helpful to bare these in mind when relating to current and previous research.
Vitamin C is good for the immune system, but did you know that it also supports tissue regeneration or that we use up 7 times more Vitamin C during stress?
Get a deeper introduction to new Fascia Research with the 2018 German documentary “The mysterious world under the skin”.
In early 2013, a German documentary was broadcast based on the latest research on the Fascia. It provides a very basic introduction for newcomers. To help you get a quick overview of Fascia, we have cut together a 10 minute version.
Dr Heike Jäger, Professor Karl Arfors and innovator Hans Bohlin presented the latest research regarding Fascia, inflammation and Fascia treatment in Stockholm, May 2017.
Exclusive interview with Gil Headly explaining how Fascia changes the perspective on how we look at the body at the 2015 Fascia Research Congress in Washington DC.
David Lesondak describes how stretching the fascia is vital for rehabilitation from injury at the 2018 Fascia Research Congress in Berlin
The new discoveries and knowledge about Fascia has taken us back to an observing stage – we have to investigate our surroundings to get an understanding for what to measure.
What we do know for sure is that the abundance of sugar has a negative effect on the fascia and makes it less elastic. Stress also affects the fascia in a disadvantageous way
Fascia is a system of flexible connective tissue encapsulating everything in the body. If the system is running smoothly, all is fine, but when some parts become stiff, tense or inflamed, there will be consequences.
Fascia is a new perspective, a completely new way of looking at the body, a new way of conducting research and a new way of understanding the world. So how do you learn to understand Fascia?
Recently, a German researcher showed that the connective tissue in a human transports 15 l of water in 48 hours, which is a relatively large amount compared to for example the amount of blood and the lymphatic system.
Fascia research has sparked an ongoing global revolution in the anatomical research field. In The Fascia Guide Research Database we have gathered hundreds of research articles about fascia.
A lot of injuries after a long break might not be that unusual – but why do so many female athletes suffer from cruciate ligament injuries?
In the 70s when the orthopedic surgeon Dr. Stephen Levin was at a natural history museum and saw the wires holding up the neck of a dinosaur, he did not get the picture to go together. How could his neck have been held up originally?