Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
- A2019
Distinct fibroblast subsets drive inflammation and damage in arthritis
Adam P Croft, Joana Campos, Kathrin Jansen, Jason D Turner, Jennifer Marshall, Moustafa Attar, Loriane Savary, Corinna…This study in mice investigated the role of fibroblasts, a type of connective tissue cell, in arthritis. Researchers identified two distinct subsets of fibroblasts with different functions. One type, located in the syno…
Synovial fibroblasts; inflammation; arthritis; transcriptomics; rheumatoid arthritis - A++2019
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
Alpha A Fowler, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday, Bernard Fisher, Leroy…This randomized controlled trial investigated whether intravenous vitamin C could help patients with sepsis and severe acute respiratory failure. Researchers gave 167 patients either a high-dose vitamin C infusion or a…
sepsisintravenous vitamin C - A++2019
8 natural supplements to help fight inflammation
Zawn VillinesInflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…
inflammationomega-3curcumin - A++2019
Role of fasciae around the median nerve in pathogenesis of carpal tunnel syndrome: microscopic and ultrasound study
Carla Stecco, Federico Giordani, Chenglei Fan, Carlo Biz, Carmelo Pirri, Anna Chiara Frigo, Caterina Fede, Veronica Mac…This study investigated the connection between the median nerve and its surrounding fascia in carpal tunnel syndrome. Using microscopic analysis of tissue samples and ultrasound imaging of both healthy subjects and pati…
carpal tunnel syndrome; double crush syndrome; fasciae; median nerve; paraneural sheath; ultrasound. - A++2019
Acute Effects of Static Stretching on Muscle Strength and Power: An Attempt to Clarify Previous Caveats
Helmi Chaabene, David G Behm, Yassine Negra, Urs GranacherThis narrative review examines how static stretching affects subsequent strength and power. While static stretching was once thought to hinder performance, recent evidence suggests the duration of the stretch is the cri…
physiologyrange of motioninjurypassive stretchingphysical fitness - A++2019
A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
Liane Bolke, Gerrit Schlippe, Joachim Gerß, Werner VossThis randomized, placebo-controlled study investigated the effects of a drinkable nutraceutical containing 2.5g of collagen peptides, vitamins, and minerals on skin health in women aged 35 and older. Over twelve weeks,…
aging; beauty; bioavailability; collagen peptides; corneometry; cutometry; high coverage [HC] collagen complex; wrinkles - C2019
Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models
Anne-Laure Papa, Amanda Jiang, Netanel Korin, Michelle B Chen, Erin T Langan, Anna Waterhouse, Emma Nash, Jildaz Carof,…Platelets are crucial for blood clotting but can also contribute to thrombosis and cancer metastasis. In this preclinical study, researchers created modified human platelets, called "platelet decoys," that retained thei…
Plateletplatelet decoystrombosismetastatic tumors - 1A+2019
Sensitivity of the fasciae to sex hormone levels: Modulation of collagen-I, collagen-III and fibrillin production
Caterina Fede, Carmelo Pirri, Chenglei Fan, Giovanna Albertin, Andrea Porzionato, Veronica Macchi, Raffaele De Caro, Ca…Women experience myofascial pain more often than men, and evidence suggests fascia can be influenced by sex hormones. In this lab study, researchers examined how cells from human fascia lata responded to various levels…
fasciacollagen Icollagen IIIsex hormones - B2019
Modeling and simulation of musculoskeletal system of human lower limb based on tensegrity structure
Zhanxi Wang, Chaoran Yang, Kang Feng, Xiansheng QinResearchers created a computer model of the human lower limb's musculoskeletal system using tensegrity principles, which balance tension and compression. Using an established muscle model (the Hill model), they simulate…
Tensegrity structure; lower limb model; motion analysis; gait simulation - A2019
Myofascial Chains of the Upper Limb: A Systematic Review of Anatomical Studies
JAN WILKE, FRIEDER KRAUSEThis systematic review compiled research to determine if myofascial chains, previously identified in the trunk and lower limbs, also exist in the upper limb. Analyzing 13 anatomical dissection studies, the authors found…
continuity; fascia; force transmission; muscles; cadavers; connective tissue; myofascial chains - A+++2019
A comparative multi-site and whole-body assessment of fascia in the horse and dog: a detailed histological investigation
Waqas Ahmed, Marta Kulikowska, Trine Ahlmann, Lise C Berg, Adrian P Harrison, Vibeke Sødring ElbrøndThis animal study compared the microscopic structure of fascia in horses and dogs across multiple body regions. Researchers found that horse fascia is generally tight and dense, while dog fascia is looser and more simil…
deep fascia; dog; histology; horse; hypodermis; myofascial kinetic lines; superficial fascia. - A2019
High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition
Ling-Hui Zeng, Qing-Mei Wang, Lin-Yi Feng, Yu-Dun Ke, Qian-Zi Xu, An-Yi Wei, Chong Zhang, Rong-Biao YingThis study on breast cancer cells in the lab and in mice explored how different doses of vitamin C affect cancer cell behavior. Researchers found that low and medium doses of vitamin C seemed to encourage cancer cells t…
Breast cancermetastasisTGF-β1Vitamin C - A++2019
Observation using thermography of post-operative reaction after fascial manipulation®
Joanna Fidut-Wrońska, Kamil Chołuj, Justyna Chmiel, Katarzyna Pikto-Pitkiewicz, Piotr MajcherThis study investigated whether Fascial Manipulation® causes a local increase in skin temperature, which is theorized to be part of its mechanism. Researchers used a thermal-imaging camera to measure skin temperature in…
inflammationFascial manipulationthermography - A++2019
Fascial organisation of motor synergies: a hypothesis
Alessandro Garofolini, Daris SvaneraThis hypothesis paper explores how fascia helps organize movement through what are known as motor synergies. It suggests that instead of the brain controlling every muscle individually, the fascial system acts as a phys…
Motor control; degrees of freedom; movement coordination; muscle spindle; myofascial continuity. - A++2019
Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats
Marta Toral, Iñaki Robles Vera, Néstor de la Visitación, Miguel Romero, Manuel Sánchez, Manuel Gómez Guzmán, Alba Rodri…This animal study investigated the link between gut bacteria, the immune system, and blood pressure in rats. Researchers transplanted gut microbiota between spontaneously hypertensive rats and rats with normal blood pre…
hypertensionendothelial dysfunctiongut dysbiosisimmune cells - C2019
Modelling Cell Origami via a Tensegrity Model of the Cytoskeleton in Adherent Cells
Lili Wang, Weiyi ChenResearchers created a computer model to better understand "cell origami," a technique where the natural pulling forces of cells are used to fold tiny structures. This model represents the cell's internal framework, or c…
Tensegritycytoskeletoncell adhesioncell origami - A2019
Where is your head? Perception of relative position of the head on a wielded object
Jeffrey B Wagman, Takahiro HiguchiThis study explored how we perceive our body's position relative to an object we are holding or balancing. Researchers specifically tested this by having participants "wield" an object with their head, a body part not t…
Haptics . Perception and action . Touch - A2019
Biotensegrity or Fascintegrity
Bruno Bordoni, Matthew A Varacallo, Bruno Morabito, Marta SimonelliIn this theoretical review, the authors question the popular "biotensegrity" model for describing the body's mechanics. They argue the model is incomplete because it fails to account for crucial factors like bodily flui…
fasciaMyofascialOsteopathicphysiotherapyskeletal muscle - A2019
The neural basis of the senses of effort, force and heaviness
Uwe Proske, Trevor AllenThis narrative review explores how we sense effort, force, and heaviness during muscle contraction. Traditionally, these sensations were thought to originate in the brain from copies of motor commands. However, new evid…
Force sense · Proprioception · Muscle spindle · Tendon organ · Motor command · Efference copy · Vibration - 1A++2019
Evaluation of hyaluronan content in areas of densification compared to adjacent areas of fascia
E J Hughes, K McDermott, M F FunkThis entry is currently a title only, so a full summary is not available. Based on the title, the researchers appear to have evaluated and compared the hyaluronan content in areas of fascial densification with the conte…
hyaluronanfasciadensificationcenters of coordination - A+++2019
Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials
Juan Mario García-Coronado, Lorena Martínez-Olvera, Rodrigo E Elizondo-Omaña, Carlos Alberto Acosta-Olivo, Félix Vilche…This meta-analysis of five randomized placebo-controlled trials evaluated the impact of oral collagen supplementation on osteoarthritis (OA) symptoms. The findings suggest that collagen may help reduce the overall disea…
Collagen supplementation; Meta-analysis; Osteoarthritis symptoms; Visual Analogue Scale; WOMAC index - A2019
The effects of vibration-induced altered stretch reflex sensitivity on maximal motor unit firing properties
Alejandra Barrera-Curiel, Ryan J Colquhoun, Jesus A Hernandez-Sarabia, Jason M DeFreitasResearchers investigated how muscle vibration, which affects the stretch reflex, influences muscle strength and nerve signals during maximal effort. In a study with 24 participants performing maximal knee extensions, th…
group Ia afferents; muscle spindle function; muscle vibration - A2019
Fascial Nomenclature: Update on Related Consensus Process
Robert Schleip, Gil Hedley, Can A YucesoyThe term "fascia" is increasingly used across different health-oriented fields, but often inconsistently, which causes confusion. To address this, the Fascia Research Society established a Fascia Nomenclature Committee.…
fascia; terminology; Delphi technique; nomenclature; connective tissue - A2019
Effects of foam rolling on performance and recovery: A systematic review of the literature to guide practitioners on the use of foam rolling
Sharief Hendricks, Hayd'n Hill, Steve den Hollander, Wayne Lombard, Romy ParkerThis systematic review analyzed 49 studies to understand how foam rolling affects athletic performance and recovery. The authors found evidence that foam rolling can decrease muscle stiffness and improve range of motion…
FlexibilityFoam rollingPerformanceRecovery - A2019
Structural Gender Dimorphism and the Biomechanics of the Gluteal Subcutaneous Tissue: Implications for the Pathophysiology of Cellulite
Christina Rudolph, Casey Hladik, Hassan Hamade, Konstantin Frank, Michael S Kaminer, Doris Hexsel, Robert H Gotkin, Nei…This study investigated gender differences in the subcutaneous tissue of the gluteal region to better understand the development of cellulite. Researchers found that men have more and stronger fibrous connections (septa…
celluliteAGEfatty tissuemorpholgygender - A2019
Improving the New Definition of Fascial System
Bruno BordoniThis narrative review proposes expanding the definition of the fascial system to include bone tissue. The author argues that bone, a specialized form of connective tissue, shares the same embryological origins as other…
fasciaChiropracticosteopathyManual Therapyfascial system - B2019
Collagenase Clostridium Histolyticum for the Treatment of Edematous Fibrosclerotic Panniculopathy (Cellulite): A Randomized Trial
Neil S Sadick, Mitchel P Goldman, Genzhou Liu, Neil H Shusterman, Michael P McLane, David Hurley, V Leroy YoungThis randomized, double-blind clinical trial evaluated the effectiveness of an enzyme injection, collagenase clostridium histolyticum (CCH), for treating cellulite. Researchers treated 375 women with moderate to severe…
cellulitescollagenas - A2019
Anatomy, Fascia
Bruno Bordoni, Navid Mahabadi, Matthew VaracalloThis resource provides an overview of the anatomy of fascia. As the full text has not yet been reviewed, this summary is based on the title alone. The entry likely covers the structural and functional aspects of fascial…
fascia - A+2019
Collagen changes in pelvic support tissues in women with pelvic organ prolapse
Runqi Gong, Zhijun XiaThis narrative review summarizes research on how changes in collagen are linked to pelvic organ prolapse in women. Collagen is a critical component of the pelvic floor, providing essential supportive functions. Studies…
extracellular matrixcollagenBiomechanicsPelvic organ prolapseSignaling pathways - B2019
Blocking around the transversalis fascia: behind the scene
Francesco Vasques, Carla Stecco, Raffaele Mitri, Raffaele De Caro, Pierfrancesco Fusco, Astrid U BehrThis cadaver study investigated the anatomy of the transversalis fascia, a thin layer of connective tissue in the abdominal wall, to understand its role in certain nerve blocks. Through dissection and microscopic analys…
Nerve block - abdominal wallanatomy and histology - Fascia. - A2019
Fascial Nomenclature: An Update
Bruno Bordoni, Stevan Walkowski, Bruno Morabito, Matthew A VaracalloThis review article discusses the ongoing challenge of creating a single, comprehensive definition for fascia. The authors argue that different scientific and clinical fields view fascia through their own unique lenses,…
fasciamechanotransductionMyofascialOsteopathicphysiotherapy - A+++2019
Active interfacial dynamic transport of fluid in a network of fibrous connective tissues throughout the whole body
Hongyi Li, Yajun Yin, Chongqing Yang, Min Chen, Fang Wang, Chao Ma, Hua Li, Yiya Kong, Fusui Ji, Jun HuInterstitial fluid, the fluid in the spaces between our cells, has long been thought to move only over short distances. This study proposes a different view, suggesting that a network of fibrous connective tissues acts…
interstitial fluidinterstitiuminterstitial spacesfascia fluid - A2019
Age-related changes in leg proprioception: implications for postural control
Mélanie Henry, Stéphane BaudryThis narrative review examines how aging affects proprioception—the body's sense of its own position and movement—and its implications for balance. To maintain an upright stance, the brain relies on signals from recepto…
proprioceptionmuscle spindlesbalanceIa afferentsupright standing - A2019
Oral Collagen Supplementation: A Systematic Review of Dermatological Applications
Franchesca D Choi, Calvin T Sung, Margit L W Juhasz, Natasha Atanaskova MesinkovskThis systematic review examined eleven clinical trials investigating the impact of oral collagen supplements on skin health. The findings suggest that collagen hydrolysates and peptides may improve skin elasticity, hydr…
wound healingcollagenskin aging - A2019
Trigger Points, Pressure Pain Hyperalgesia, and Mechanosensitivity of Neural Tissue in Women with Chronic Pelvic Pain
Pedro Fuentes-Márquez, Marie Carmen Valenza, Irene Cabrera-Martos, Ana Ríos-Sánchez, Olga Ocón-HernándezIn this case-control study, researchers compared women with chronic pelvic pain to a healthy control group. They found that women with pelvic pain had significantly more myofascial trigger points in their low back, glut…
Myofascial Pain Syndrome; Pressure Algometry; Neurodynamics; Chronic Pelvic Pain - A+++2019
Tentorium Cerebelli: the Bridge Between the Central and Peripheral Nervous System, Part 2
Bruno Bordoni, Marta Simonelli, Maria Marcella LaganaThis article, the second in a series, describes the tentorium cerebelli—a meningeal structure related to the skull, nervous system, and cervical spine. The authors discuss its complex relationships, including its neurol…
fasciapaincraniotentorium cerebellivenous circulation - A+2019
Role of a natural integrator based on lipoic acid, palmitoiletanolamide and myrrh in the treatment of chronic pelvic pain and endometriosis
Vincenzo De Leo, Angelo Cagnacci, Valentina Cappelli, Anna Biasioli, Deborah Leonardi, Renato SeracchioliThis study investigated a nutritional supplement for endometriosis-related pain. Sixty women with ovarian endometriosis and chronic pelvic pain took a supplement containing alpha-lipoic acid, palmitoylethanolamide (PEA)…
nutraceuticalendometriosispelvic painantioxidant - A+++2019
Is It All About the Fascia? A Systematic Review and Meta-analysis of the Prevalence of Extramuscular Connective Tissue Lesions in Muscle Strain Injury
Jan Wilke, Luiz Hespanhol, Martin BehrensThis systematic review and meta-analysis examined how often connective tissue is damaged in athletic muscle strains. Researchers analyzed 16 imaging studies and found that lesions to the fascia and tendons are highly pr…
return to play; muscle injury; collagen; imaging; ultrasound; MRI - A2019
Intravascular heavy chain-modification of hyaluronan during endotoxic shock
Kevin Ni, Amar Gill, Danting Cao, Kengo Koike, Kelly S Schweitzer, Stavros Garantziotis, Irina PetracheIn this animal study, researchers investigated why a specific molecule, HC-modified hyaluronan (HC-HA), is critical for survival in systemic inflammation (like endotoxic shock) but less so in localized lung inflammation…
Hyaluronic acidInter-alpha-inhibitorSerum-derived hyaluronan-associated proteinTNFα stimulated gene 6Endotoxic shock - A++2019
Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats
Fusako Usuki, Masatake Fujimura, Atsushi Nakamura, Jiro Nakano, Minoru Okita, Itsuro HiguchiThis study on rats investigated whether local vibration could help muscles recover after being immobilized. Researchers put a cast on one hindlimb of the rats for a week to induce muscle atrophy. After removing the cast…
YAP1; local vibration; mechano-growth factor; mechanotransduction; oxidative myofiber atrophy; satellite cell; therapeutics. - A2019
Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis
Tabea C Hornung, Hans-Konrad BiesalskiUnlike many animals, humans cannot produce their own vitamin C. This study explores a potential evolutionary advantage of this loss. Researchers compared red blood cells from humans and pigs (who can make vitamin C) and…
glucose transporter; vitamin C; gulono-lactone-oxidase; vitamin C recycling - B2019
TMEM2: a missing link in hyaluronan catabolism identified?
Yu Yamaguchi, Hayato Yamamoto, Yuki Tobisawa, Fumitoshi IrieHyaluronan (HA) is a large molecule in our connective tissues that is broken down and replaced very quickly. Scientists have long understood that large HA molecules are first chopped into smaller pieces on the surface o…
hyaluronanhyaluronidaseTMEM2HA catabolism - A2019
Hyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor
Stephan Thönes, Sandra Rother, Tom Wippold, Joanna Blaszkiewicz, Kanagasabai Balamurugan, Stephanie Moeller, Gloria Rui…This study investigated a new type of hydrogel designed to improve wound healing. Researchers combined collagen and hyaluronan (HA), a natural component of connective tissue, with a growth factor that stimulates skin ce…
Biomimetic material; Extracellular matrix (ECM); Fibroblasts; Heparin-binding epidermal growth factor-like growth factor (HB-EGF); Hyaluronan; Hydrogel; Sulfated hyaluronan; Surface plasmon resonance; Wound healing. - B2019
Hyaluronan fragments produced during tissue injury: A signal amplifying the inflammatory response
Angela Avenoso, Giuseppe Bruschetta, Angela D'Ascola, Michele Scuruchi, Giuseppe Mandraffino, Rosa Gullace, Antonino Sa…This narrative review examines how fragments of hyaluronan (HA), a major component of the extracellular matrix, contribute to inflammation. During tissue injury, large HA molecules are broken down into smaller pieces. E…
Hyaluronan fragments NF-kB TLR-4 Cytokines Tissue damage Inflammation Hyaluronan degradation - A+++2019
Vitamin C administration in the critically ill: a summary of recent meta-analyses
Anitra C CarrThis 2019 publication is a summary of recent meta-analyses on the topic of vitamin C administration for critically ill patients. As the full text has not yet been reviewed, a detailed summary of its findings is not avai…
Vitamin CAscorbic acidsepsis - A2019
Experimental myofascial trigger point creation in rodents
Ramon Margalef, Marc Sisquella, Marc Bosque, Clara Romeu, Orlando Mayoral, Sonia Monterde, Mercedes Priego, Rafael Guer…This animal study investigated how myofascial trigger points might form. Researchers treated mice and rats with a substance that increases nerve signals to the muscles, mimicking a state of high neurotransmission. This…
animal model; endplate noise; myofascial pain syndrome; myofascial trigger point; spontaneous acetylcholine release - A2019
Cellular nanoscale stiffness patterns governed by intracellular forces
Nicola Mandriota, Claudia Friedsam, John A Jones-Molina, Kathleen V Tatem, Donald E Ingber, Ozgur SahinCell stiffness is important in many biological processes, but its precise relationship to the forces acting inside the cell has been unclear. In this study, researchers developed a new high-resolution imaging platform t…
Tensegritymechanotransductioncell - cell interaction - A+++2019
Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience
Patrick J McCullough, Douglas S Lehrer, Je!rey AmendThis observational study followed long-term hospitalized patients over seven years to evaluate the safety of high daily doses of vitamin D3. Patients received supplements ranging from 5,000 to 50,000 international units…
vitamin DIntact parathyroid hormoneLong-term supplementationAdverse events - A++2019
Induced lumbosacral radicular symptom referral patterns: a descriptive study
Michael B Furman, Stephen C JohnsonThis observational study investigated actual pain patterns caused by irritating specific nerve roots in the lower back. Clinicians often use standard 'dermatome' maps to diagnose the source of radiating leg pain, but pa…
dermatomes; nerve; communications; map; cutaneous; sensory - B2019
Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology
Saba Nayar, Joana Campos, Charlotte G Smith, Valentina Iannizzotto, David H Gardner, Frédéric Mourcin, David Roulois, J…In sites of chronic inflammation or infection, connective tissue cells called fibroblasts can change their behavior. This study shows how a specific group of fibroblasts transforms into a network of so-called "immunofib…
FibroblastsSjögren’s syndromeautoimmunitytertiary lymphoid structures - A++2019
The architecture and spatial organization of the living human body as revealed by intratissular endoscopy - An osteopathic perspective
Colin ArmstrongThis review article discusses research by Dr. Jean-Claude Guimberteau, who used endoscopy to visualize the internal architecture of the living body. His work reveals a continuous, body-wide multifibrillar network that t…
fasciaextracellular matrixosteopathyCollagen fibersFibrillar network - A++2019
Mechanics and structural stability of the collagen triple helix
Michael W H Kirkness, Kathrin Lehmann, Nancy R FordeThis narrative review explores the mechanical properties of collagen, the body's primary structural protein. Collagen's unique triple helix structure is believed to be the source of its stability and resilience in tissu…
collagentriple helix - A+2019
Overuse Injury: The Result of Pathologically Altered Myofascial Force Transmission?
Jan Wilke, Andry Vleeming, Scott WearingIn this narrative review, the authors propose a new perspective on overuse injuries. Traditionally, therapy focuses on the site of pain, viewing the injury as the result of local, repetitive microdamage. The authors hyp…
Myofascial force transmissionoveruse injuryfascitismusculoskeletal disorder - A2019
Lipedema: friend and foe
Yanira Sanchez-De la Torre, Rita Wadeea, Victoria Rosas, Karen L HerbstLipedema is a chronic disorder characterized by painful, disproportionate fat accumulation in the limbs of women, and is often misdiagnosed as obesity. In this review, researchers examined both the negative ('foe') and…
gynoid fat; hypermobility; lipedema; lymphedema; women - 1A+2019
The Awareness of the Fascial System
Bruno Bordoni, Marta SimonelliIn this theoretical article, the authors propose a new way of looking at the fascial system, drawing on concepts from quantum physics. They suggest that fascial cells can sense, remember, and even anticipate mechanical…
fasciafascial systemMyofascialquantum physicsphysiology - A2019
Genetics of lipedema: new perspectives on genetic research and molecular diagnoses
S Paolacci, V Precone, F Acquaviva, P Chiurazzi, E Fulcheri, M Pinelli, F Buffelli, S Michelini, K L Herbst, V Unfer, M…This 2019 review explored the genetic basis of lipedema. The researchers summarized existing knowledge to highlight the need for a genetic test to aid in diagnosis. They identified several genetic factors that may be re…
lipedemalipoedemaDifferential diagnosisSubcutaneous fatGenetic diagnosis - 1A+2019
The fascial breath
Bruno Bordoni, Marta Simonelli, Bruno MorabitoThis narrative review proposes a new way of understanding the diaphragm muscle, moving beyond a purely mechanical view. The authors argue that the diaphragm is not just covered by fascia but is fundamentally a fascial t…
fasciaMyofascialOsteopathicdiaphragmbreathing - B2019
The Fascial Connections of the Pectineal Ligament
Hanno Steinke, Dina Wiersbicki, Anna Völker, Philipp Pieroh, Charlotte Kulow, Benjamin Wolf, Georg OsterhoffThis anatomical study investigated the detailed fascial connections of the pectineal ligament using dissection and analysis of ten human specimens. Researchers found the ligament acts as a connective tissue junction bet…
tendinous arch of levator aniiliopubic tract; obturator fascia; pectineal ligamentpectineal fascia; Waldeyers’ fascia; Gerota’s fascia; Zuckerkandl’s fascia; Toldt’s fascia - A2019
Intra-articular effects of combined xenogenous serum rich in growth factors (SRGF) and vitamin C on histopathology grading and staging of osteoarthritis in rat model
S Azizi, A Farsinejad, R Kheirandish, H FatemiThis animal study investigated a potential treatment for osteoarthritis (OA) in rats. Researchers induced OA in the rats' knees and then treated them with intra-articular injections. One group received a combination of…
Osteoarthritis; SRGF; Monosodium iodoacetate; Vitamin C; Histopathology - A+++2019
An extravascular fluid transport system based on structural framework of fibrous connective tissues in human body
Hongyi Li, Chongqing Yang, Yajun Yin, Fang Wang, Min Chen, Liang Xu, Naili Wang, Di Zhang, Xiaoxia Wang, Yiya Kong, Qin…Researchers investigated a potential fluid transport system within the body's fibrous connective tissues, separate from blood and lymphatic vessels. Using fluorescent tracers in cadavers and MRI in volunteers, they visu…
interstitial fluidinterstitiuminterstitial spacesfascia fluid