Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2016
Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase
Sebastian Kalamajski, Dominique Bihan, Arkadiusz Bonna, Kristofer Rubin, Richard W FarndaleFibrosis is characterized by a dense and stiff collagen matrix, formed through a cross-linking process driven by the enzyme lysyl oxidase (LOX). This study investigated the role of another protein, fibromodulin, in this…
fibrosiscollagen cross-linkingfibromodulinlysyl oxidase - C2016
Protein—glycosaminoglycan interaction networks: Focus on heparan sulfate
Sylvie Ricard-BlumThis research overview describes a project focused on glycosaminoglycans (GAGs), complex sugars found on the cell surface and in the extracellular matrix. Specifically, it investigates heparan sulfate and how it interac…
extracellular matrixHeparan sulfateInteraction networksInteraction databasesSurface plasmon resonance - A2016
Systemic inflammatory profiles and their relationships with demographic, behavioural and clinical features in acute low back pain
David M Klyne, Mary F Barbe, Paul W HodgesThis study investigated systemic inflammation in acute low back pain, which is less studied than inflammation in chronic conditions. Researchers analyzed blood samples from 99 individuals within two weeks of LBP onset a…
Pro-inflammatory cytokinesC-reactive protein (CRP)Interleukin-6 (IL-6)Tumor necrosis factor (TNF)Interleukin-1beta (IL-1beta) - A2016
Restoration of Full Shoulder Range of Motion After Application of the Fascial Distortion Model
Joshua D Boucher, Jose FigueroaThis case report describes a 28-year-old man with chronic shoulder pain and severely limited movement, 18 months after an injury. His condition, similar to a frozen shoulder, involved significant pain and an inability t…
frozen shoulderfascial distortion modelrange of motion - C2016
Functional in vitro tension measurements of fascial tissue – a novel modified superfusion approach
Robert Schleip, Werner Klingler, S Wearing, I Naylor, M Zuegel, K HoppeIn this laboratory study on rat tissue, researchers compared two techniques for measuring tension changes in fascia. The traditional method involves immersing the tissue in a fluid bath, but the team also tested a modif…
fasciaOrgan BathMechanographic RegistrationSuperfusionImmersionmized Mice - A2016
Patterns of attachment of the myodural bridge by the rectus capitis posterior minor muscle
Xiao-Ying Yuan, Sheng-Bo Yu, Yun-Fei Li, Yan-Yan Chi, Nan Zheng, Hai-Bin Gao, Bing-Yi Luan, Zhao-Xi Zhang, Hong-Jin SuiThis anatomical study used dissection and plastination techniques to examine the myodural bridge, a small tissue connection in the upper neck. Researchers focused on the attachments of the rectus capitis posterior minor…
Myodural Bridgerectus capitis posterior minor muscleChronic cervicogenic headacheCirculation of cerebrospinal fluidPlastination technology - A++2016
The effect of an active vibration stimulus according to different shoulder joint angles on functional reach and stability of the shoulder joint
Eun-Kyung Kim, Seong-Gil KimThis study investigated how active vibration exercise with a Flexi-Bar at different shoulder angles affected shoulder joint function and stability in 30 healthy male students. Participants were divided into three groups…
Active vibration stimulusFlexi-BarShoulder joint angle - A++2016
Effects of matrix rhythm therapy on primary lymphedema: a case report
Ayse Neriman Narin, Ayse Zengin Alpozgen, Hilal Denizoglu KulliThis case report investigated the effects of Matrix Rhythm Therapy on a 36-year-old woman with primary lymphedema in her left leg. She received 20 sessions of the therapy over four weeks, applied to the affected leg, sp…
Matrix Rhythm TherapyLower limbPrimary lymphedema - A2016
A five year follow-up of women with obstetric anal sphincter rupture at their first delivery
Sidsel Linneberg, Stine Leenskjold, Karin GlavindThis study followed 82 women for five years after they experienced an obstetric anal sphincter rupture (OASR) during their first delivery. Researchers investigated long-term outcomes like incontinence and sexual functio…
urinary incontinenceanal incontinenceObstetric anal sphincter ruptureSexual dysfunctionValidated questionnaires - B2016
Stretch-induced network reconfiguration of collagen fibres in the human facet capsular ligament
Sijia Zhang, Danielle S Bassett, Beth A WinkelsteinThe facet capsular ligament in the neck is a common source of chronic pain, often resulting from excessive stretching. This study investigated how the collagen fibers within this ligament reorganize when it is stretched…
collagenfibre realignmentfacet capsular ligamentcommunity detectiontime-dependent network - A2016
What Is Evidence-Based About Myofascial Chains: A Systematic Review
Jan Wilke, Frieder Krause, Lutz Vogt, Winfried BanzerThis systematic review evaluated anatomical dissection studies to find evidence for six proposed myofascial meridians. Researchers analyzed 62 studies and found strong evidence for the anatomical continuity of three lin…
fasciaForce transmissionmyofascial chainsmeridians - A2016
Fascial Manipulation Associated With Standard Care Compared to Only Standard Postsurgical Care for Total Hip Arthroplasty: A Randomized Controlled Trial
Massimo Busato, Cristian Quagliati, Lara Magri, Alessandra Filippi, Alberto Sanna, Mirco Branchini, Aurelie Marie March…This randomized controlled trial investigated the effects of adding Fascial Manipulation (FM) to standard rehabilitation after total hip replacement surgery. Researchers divided 51 patients into two groups: one received…
Fascial manipulationHip arthroplasty