Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2016
Monitoring the primo vascular system in lymphatic vessels by using window chambers
Jungdae Kim, Dong-Hyun Kim, Sharon Jiyoon Jung, Hyun-Ji Gil, Seung Zhoo Yoon, Young-Il Kim, Kwang-Sup SohIn this animal study, researchers developed a method for observing the primo vascular system (PVS) inside the lymphatic vessels of rats over an extended period. By implanting a "window chamber" into the skin and injecti…
primo vascular systemlymphatic vessels - A2016
Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways
Pu-Rong Chiu, Yu-Chen Hu, Tzu-Ching Huang, Bau-Shan Hsieh, Jou-Pei Yeh, Hsiao-Ling Cheng, Li-Wen Huang, Kee-Lung ChangIn this study using rat and cell models, researchers investigated if vitamin C could protect cartilage cells against osteoarthritis-like damage. The results showed that vitamin C reduced oxidative stress, inflammation,…
chondrocyte; interleukin; matrix metalloproteinase; osteoarthritis; vitamin C - A2016
Is remote stretching based on myofascial chains as effective as local exercise? A randomised-controlled trial
Jan Wilke, L Vogt, D Niederer, W BanzerThis randomized controlled trial investigated whether stretching the lower limbs could improve neck mobility as effectively as direct neck stretching. Researchers divided 63 healthy participants into three groups: one s…
Myofascial chains; force transmission; fascia; meridians; MiSpEx - A2016
Intermuscular force transmission along myofascial chains: a systematic review
Frieder Krause, Jan Wilke, Lutz Vogt, Winfried BanzerThis systematic review examined evidence for force transmission along continuous lines of muscle and fascia, often called myofascial chains. Researchers analyzed nine studies of moderate to excellent quality that invest…
anatomy trains; fascia; myofascial continuity; tension transfer - A2016
Remote effects of lower limb stretching: preliminary evidence for myofascial connectivity?
Jan Wilke, Daniel Niederer, Lutz Vogt, Winfried BanzerThis study investigated whether stretching the lower body could affect neck mobility. Twenty-six healthy participants were divided into two groups, with one group performing static stretches for the calf and hamstring m…
Myofascial chains; force transmission; fascia; meridians - A+++2016
Manual evaluation of the diaphragm muscle
Bruno Bordoni, F Marelli, B Morabito, B SacconiThe diaphragm is a vital muscle for breathing, but it also plays a key role in posture, organ function, and even emotional states. Despite its importance, there is little scientific literature on how to manually assess…
ChiropracticManual Therapydiaphragmphysiotherapyosteopathic evaluation - B2016
Hyaluronic Acid in Inflammation and Tissue Regeneration
Malgorzata Litwiniuk, Alicja Krejner, Tomasz GrzelaThis review article summarizes the role of hyaluronic acid (HA) in tissue healing. As a main component of the extracellular matrix, HA is a key player in tissue regeneration. Interestingly, its effects depend on its mol…
hyaluronic acid; extracellular matrix; wound healing; Inflammation - A2016
Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series
Preeti Raghavan, Ying Lu, Mona Mirchandani, Antonio SteccoThis case series investigated injections of the enzyme hyaluronidase to treat upper limb muscle stiffness in 20 individuals with cerebral injury. The researchers hypothesized that an accumulation of hyaluronan in the mu…
fasciaConnective tissueStrokeHypertoniaspasticity - A+2016
Piezo2 is the principal mechanotransduction channel for proprioception
Seung-Hyun Woo, Viktor Lukacs, Joriene C de Nooij, Dasha Zaytseva, Connor R Criddle, Allain Francisco, Thomas M Jessell…Proprioception is the sense of where our body parts are in space. In this animal study, researchers investigated the molecular sensor responsible for this ability in mice. They found that an ion channel called Piezo2 wa…
proprioceptionmuscle spindlespiezomechanotranductiiongolgi tendon organ - A2016
Telocytes and Their Extracellular Vesicles—Evidence and Hypotheses
Dragos Cretoiu, Jiahong Xu, Junjie Xiao, Sanda M CretoiuThis narrative review discusses telocytes, a relatively new type of interstitial cell found throughout the body's connective tissues. These cells are characterized by long projections and are involved in communication b…
telocytes; telopodes; extracellular vesicles; exosomes; ectosomes - A2016
New evidence of a dynamic fascial maintenance and self-repair process
Leon ChaitowThis 2016 publication by Leon Chaitow has not yet been summarized in detail. Based on its title, the article appears to present new findings that highlight the dynamic processes of fascial maintenance and self-repair. W…
Myofascial self repair - A+++2016
A long-distance fluid transport pathway within fibrous connective tissues in patients with ankle edema
Hongyi Li, Chongqing Yang, Kuiyuan Lu, Liyang Zhang, Jiefu Yang, Fang Wang, Dongge Liu, Di Cui, Mingjun Sun, Jianxin Pa…This anatomical study investigated how fluid might drain from swollen ankles. Researchers injected a fluorescent dye into the skin of four lower legs scheduled for amputation to trace fluid movement. They observed that…
interstitial fluidConnective tissuesvascular circulations
