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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 589–600 of 1,131 studies · page 50/95
  1. A
    2016

    Monitoring the primo vascular system in lymphatic vessels by using window chambers

    Jungdae Kim, Dong-Hyun Kim, Sharon Jiyoon Jung, Hyun-Ji Gil, Seung Zhoo Yoon, Young-Il Kim, Kwang-Sup Soh

    In this animal study, researchers developed a method for observing the primo vascular system (PVS) inside the lymphatic vessels of rats over an extended period. By implanting a "window chamber" into the skin and injecti…

    primo vascular systemlymphatic vessels
  2. A
    2016

    Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways

    Pu-Rong Chiu, Yu-Chen Hu, Tzu-Ching Huang, Bau-Shan Hsieh, Jou-Pei Yeh, Hsiao-Ling Cheng, Li-Wen Huang, Kee-Lung Chang

    In this study using rat and cell models, researchers investigated if vitamin C could protect cartilage cells against osteoarthritis-like damage. The results showed that vitamin C reduced oxidative stress, inflammation,…

    chondrocyte; interleukin; matrix metalloproteinase; osteoarthritis; vitamin C
  3. A
    2016

    Is remote stretching based on myofascial chains as effective as local exercise? A randomised-controlled trial

    Jan Wilke, L Vogt, D Niederer, W Banzer

    This randomized controlled trial investigated whether stretching the lower limbs could improve neck mobility as effectively as direct neck stretching. Researchers divided 63 healthy participants into three groups: one s…

    Myofascial chains; force transmission; fascia; meridians; MiSpEx
  4. A
    2016

    Intermuscular force transmission along myofascial chains: a systematic review

    Frieder Krause, Jan Wilke, Lutz Vogt, Winfried Banzer

    This systematic review examined evidence for force transmission along continuous lines of muscle and fascia, often called myofascial chains. Researchers analyzed nine studies of moderate to excellent quality that invest…

    anatomy trains; fascia; myofascial continuity; tension transfer
  5. A
    2016

    Remote effects of lower limb stretching: preliminary evidence for myofascial connectivity?

    Jan Wilke, Daniel Niederer, Lutz Vogt, Winfried Banzer

    This study investigated whether stretching the lower body could affect neck mobility. Twenty-six healthy participants were divided into two groups, with one group performing static stretches for the calf and hamstring m…

    Myofascial chains; force transmission; fascia; meridians
  6. A+++
    2016

    Manual evaluation of the diaphragm muscle

    Bruno Bordoni, F Marelli, B Morabito, B Sacconi

    The diaphragm is a vital muscle for breathing, but it also plays a key role in posture, organ function, and even emotional states. Despite its importance, there is little scientific literature on how to manually assess…

    ChiropracticManual Therapydiaphragmphysiotherapyosteopathic evaluation
  7. B
    2016

    Hyaluronic Acid in Inflammation and Tissue Regeneration

    Malgorzata Litwiniuk, Alicja Krejner, Tomasz Grzela

    This review article summarizes the role of hyaluronic acid (HA) in tissue healing. As a main component of the extracellular matrix, HA is a key player in tissue regeneration. Interestingly, its effects depend on its mol…

    hyaluronic acid; extracellular matrix; wound healing; Inflammation
  8. A
    2016

    Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series

    Preeti Raghavan, Ying Lu, Mona Mirchandani, Antonio Stecco

    This case series investigated injections of the enzyme hyaluronidase to treat upper limb muscle stiffness in 20 individuals with cerebral injury. The researchers hypothesized that an accumulation of hyaluronan in the mu…

    fasciaConnective tissueStrokeHypertoniaspasticity
  9. A+
    2016

    Piezo2 is the principal mechanotransduction channel for proprioception

    Seung-Hyun Woo, Viktor Lukacs, Joriene C de Nooij, Dasha Zaytseva, Connor R Criddle, Allain Francisco, Thomas M Jessell…

    Proprioception is the sense of where our body parts are in space. In this animal study, researchers investigated the molecular sensor responsible for this ability in mice. They found that an ion channel called Piezo2 wa…

    proprioceptionmuscle spindlespiezomechanotranductiiongolgi tendon organ
  10. A
    2016

    Telocytes and Their Extracellular Vesicles—Evidence and Hypotheses

    Dragos Cretoiu, Jiahong Xu, Junjie Xiao, Sanda M Cretoiu

    This narrative review discusses telocytes, a relatively new type of interstitial cell found throughout the body's connective tissues. These cells are characterized by long projections and are involved in communication b…

    telocytes; telopodes; extracellular vesicles; exosomes; ectosomes
  11. A
    2016

    New evidence of a dynamic fascial maintenance and self-repair process

    Leon Chaitow

    This 2016 publication by Leon Chaitow has not yet been summarized in detail. Based on its title, the article appears to present new findings that highlight the dynamic processes of fascial maintenance and self-repair. W…

    Myofascial self repair
  12. A+++
    2016

    A long-distance fluid transport pathway within fibrous connective tissues in patients with ankle edema

    Hongyi Li, Chongqing Yang, Kuiyuan Lu, Liyang Zhang, Jiefu Yang, Fang Wang, Dongge Liu, Di Cui, Mingjun Sun, Jianxin Pa…

    This anatomical study investigated how fluid might drain from swollen ankles. Researchers injected a fluorescent dye into the skin of four lower legs scheduled for amputation to trace fluid movement. They observed that…

    interstitial fluidConnective tissuesvascular circulations