Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2018
Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse
Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun, Dieter BlottnerThis animal study investigated how disuse affects deep fascia and bone, and whether vibration could counteract these effects. Researchers used a rat model where hindlimbs were unloaded for 21 days to simulate disuse, wh…
extracellular matrixcollagenBonedeep fasciaBiomechanics - A+++2018
Depression and anxiety in patients with chronic heart failure
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice SacconiIn this review article, the authors discuss the connection between chronic heart failure (CHF), mental health, and diaphragm function. CHF is a serious, progressive condition often accompanied by depression and anxiety.…
anxiety • baroreceptors • chronic heart failure • diaphragm • depression • inflammatory cytokines • phrenic nerve • psychiatric disorders • rehabilitation • vagus nerve - C2018
Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners?
Katarzyna Pietraszek-Gremplewicz, Konstantina Karamanou, Aïchata Niang, Manuel Dauchez, Nicolas Belloy, François-Xavier…This narrative review summarizes research on a family of proteins called small leucine-rich proteoglycans (SLRPs). These proteins are important regulators of the extracellular matrix and have been identified as potentia…
fibromodulinSLRPsLumicanDecorinBiglycan - A2018
Combined vitamin C, hydrocortisone, and thiamine therapy for patients with severe pneumonia who were admitted to the intensive care unit: Propensity score-based analysis of a before-after cohort study
Won-Young Kim, Eun-Jung Jo, Jung Seop Eom, Jeongha Mok, Mi-Hyun Kim, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Kwangha LeeThis cohort study investigated a combination therapy of vitamin C, hydrocortisone, and thiamine for ICU patients with severe pneumonia. Researchers compared a group receiving the treatment to a control group from the pr…
Ascorbic acidHydrocortisoneIntensive care unitPneumoniaThiamine - A2018
Fasciae of the musculoskeletal system: normal anatomy and MR patterns of involvement in autoimmune diseases
Thomas Kirchgesner, Xavier Demondion, Maria Stoenoiu, Patrick Durez, Adrien Nzeusseu Toukap, Frédéric Houssiau, Christi…This review article describes the fascial system as a three-dimensional continuum of connective tissue found throughout the body. The authors review the normal anatomy of fascia and its appearance on magnetic resonance…
fasciaMusculoskeletalAnatomyAutoimmuneMRI - A+++2018
Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement
Martina Zügel, Constantinos N Maganaris, Jan Wilke, Karin Jurkat-Rott, Werner Klingler, Scott C Wearing, Thomas Findley…This consensus statement reviews the current state of knowledge on fascial tissue in sports medicine. It describes fascia as a body-wide network of connective tissue that integrates all body systems and is crucial for m…
fasciainjurysports medicine - C2017
Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin
Patricia Paracuellos, Sebastian Kalamajski, Arkadiusz Bonnac, Dominique Bihanc, Richard W. Farndale, Erhard HohenesterFibromodulin and chondroadherin are small proteins that help organize the extracellular matrix. This study examined their 3D structure and how they interact with collagen. Researchers found that while their overall shap…
Cell signalingfibromodulinchondroadherinextra cellular matrix - A++2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study
Paul E Marik, Vikramjit Khangoora, Racquel Rivera, Michael H Hooper, John CatravasIn this retrospective before-after study, researchers investigated the effect of a combination therapy of intravenous vitamin C, hydrocortisone, and thiamine for patients with severe sepsis and septic shock. They compar…
corticosteroid; hydrocortisone; septic shock; thiamine; vitamin C - A+2017
Quantitative tissue parameters of Achilles tendon and plantar fascia in healthy subjects using a handheld myotonometer
Sarah Orner, Wolfgang Kratzer, Julian Schmidberger, Beate GrünerThis study examined the mechanical properties of the Achilles tendon and plantar fascia in over 150 healthy adults using a handheld device called a MyotonPRO. The goal was to establish baseline normal values for tissue…
fasciaachilles tendonplantar fasciaMyotonePRO - A++2017
Oscillations of ultra-weak photon emission from cancer and noncancer cells stressed by culture medium change and TNF-alfa
Pierre Madl, Thomas Verwanger, Mark Geppert, Felix ScholkmannAll cells spontaneously emit a very faint light, known as ultra-weak photon emission (UPE). This study investigated how this light emission changes when different types of human cells, both cancerous and non-cancerous,…
cancerBiophotonultraweak photon emission - B2017
Cellulite: a review with a focus on subcision
Daniel P Friedmann, Garrett Lane Vick, Vineet MishraThis narrative review examines cellulite, a common skin condition characterized by altered skin topography that primarily affects women on their buttocks and thighs. The authors discuss the potential underlying causes a…
gynoid lipodystrophyfibrous septaeradiofrequencyvacuum-assisted subscision - A2017
Spontaneous photon emission: A promising non-invasive diagnostic tool for breast cancer
Xiaolei Zhao, Jingxiang Pang, Jialei Fu, Yong Wang, Meina Yang, Yanli Liu, Hua Fan, Liewei Zhang, Jinxiang HanIn this animal study, researchers investigated if ultra-weak light emission from the body, called spontaneous photon emission (SPE), could detect breast cancer. They measured light from the skin of mice with breast canc…
Breast cancerSpontaneous photon emission (SPE)Preliminary screeningCluster analysisOxidative metabolic