Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804

studies

602

top-graded

2,783

with plain-language summary

SortBy grade By year A–Z

View

List Grid

Showing 361–420 of 736 studies · page 7/13Since 2015

Clear

A+++
2019
An extravascular fluid transport system based on structural framework of fibrous connective tissues in human body
Hongyi Li, Chongqing Yang, Yajun Yin, Fang Wang, Min Chen, Liang Xu, Naili Wang, Di Zhang, Xiaoxia Wang, Yiya Kong, Qin…
Researchers investigated a potential fluid transport system within the body's fibrous connective tissues, separate from blood and lymphatic vessels. Using fluorescent tracers in cadavers and MRI in volunteers, they visu…
interstitial fluidinterstitiuminterstitial spacesfascia fluid
A+++
2019
Active interfacial dynamic transport of fluid in a network of fibrous connective tissues throughout the whole body
Hongyi Li, Yajun Yin, Chongqing Yang, Min Chen, Fang Wang, Chao Ma, Hua Li, Yiya Kong, Fusui Ji, Jun Hu
Interstitial fluid, the fluid in the spaces between our cells, has long been thought to move only over short distances. This study proposes a different view, suggesting that a network of fibrous connective tissues acts…
interstitial fluidinterstitiuminterstitial spacesfascia fluid
A++
2019
Acute Effects of Static Stretching on Muscle Strength and Power: An Attempt to Clarify Previous Caveats
Helmi Chaabene, David G Behm, Yassine Negra, Urs Granacher
This narrative review examines how static stretching affects subsequent strength and power. While static stretching was once thought to hinder performance, recent evidence suggests the duration of the stretch is the cri…
physiologyrange of motioninjurypassive stretchingphysical fitness
A++
2019
Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients
Stephan F E Praet, Craig R Purdam, Marijke Welvaert, Nicole Vlahovich, Gregg Lovell, Louise M Burke, Jamie E Gaida, Sil…
This pilot study investigated whether supplementing with specific collagen peptides could improve symptoms for patients with chronic Achilles tendinopathy. Participants combined a calf-strengthening program with either…
achilles tendon; microvessels; contrast-enhanced ultrasound; hydrolysed collagen supplementation
A
2019
Bone Broth Unlikely to Provide Reliable Concentrations of Collagen Precursors Compared With Supplemental Sources of Collagen Used in Collagen Research
Rebekah D Alcock, Gregory C Shaw, Louise M Burke
This study analyzed the amino acid content of bone broth to assess it as a reliable source of collagen precursors, the building blocks the body uses to make collagen. Researchers compared various broths—commercial, home…
gelatine; glycine; ligament; proline; protein; tendon
A++
2019
Mitochondrial superoxide anions induced by exogenous oxidative stress determine tumor cell fate: an individual cell-based study
Hui PAN, Bao-hui WANG, Zhou-bin LI, Xing-guo GONG, Yong QIN, Yan JIANG, Wei-li HAN
In this cell-based study, researchers investigated how external oxidative stress affects individual lung cancer cells. They found that applying a stressor like hydrogen peroxide caused a rapid increase in reactive oxyge…
Individual cell; Superoxide anion; Reactive oxygen species (ROS) dynamics; Intrinsic apoptotic pathway; Ca2+ signaling
A+
2019
Ultrasound-detected connective tissue involvement in acute muscle injuries in elite athletes and return to play: The French National Institute of Sports (INSEP) study
Jérôme Renoux, Jean-Louis Brasseur, Mathilde Wagner, Alain Frey, Dominique Folinais, Christian Dibie, Djamila Maiza, Mi…
This study examined 70 elite athletes with acute muscle injuries. Researchers used ultrasound within seven days to assess injury severity and to see if connective tissue was involved. They then tracked the time it took…
ultrasound.return to playMuscle injuriesConnective tissue injury
A
2019
Hierarchical Hydrogel Composite Interfaces with Robust Mechanical Properties for Biomedical Applications
Yuting Zhu, Qiang Zhang, Xiaoli Shi, Dong Han
This review summarizes advances in hydrogel composites, materials designed to mimic the body's extracellular matrix (ECM). Cells naturally sense and respond to the mechanical properties and physical structure of the ECM…
tissue engineeringECMHydrogels
A
2019
Association of thoraco-lumbar fascia length in individuals with non-specific low back pain - an observational study
Shellette D' Almeida, Charu Eapen, Shyam Krishnan
This observational study compared 31 people with non-specific low back pain to 31 healthy individuals to investigate the thoracolumbar fascia (TLF). Researchers measured TLF length by assessing lumbar spine rotation, an…
low back painthoracolumar fascia lenght
A
2019
Structural Gender Dimorphism and the Biomechanics of the Gluteal Subcutaneous Tissue: Implications for the Pathophysiology of Cellulite
Christina Rudolph, Casey Hladik, Hassan Hamade, Konstantin Frank, Michael S Kaminer, Doris Hexsel, Robert H Gotkin, Nei…
This study investigated gender differences in the subcutaneous tissue of the gluteal region to better understand the development of cellulite. Researchers found that men have more and stronger fibrous connections (septa…
celluliteAGEfatty tissuemorpholgygender
B
2019
Collagenase Clostridium Histolyticum for the Treatment of Edematous Fibrosclerotic Panniculopathy (Cellulite): A Randomized Trial
Neil S Sadick, Mitchel P Goldman, Genzhou Liu, Neil H Shusterman, Michael P McLane, David Hurley, V Leroy Young
This randomized, double-blind clinical trial evaluated the effectiveness of an enzyme injection, collagenase clostridium histolyticum (CCH), for treating cellulite. Researchers treated 375 women with moderate to severe…
cellulitescollagenas
A+++
2019
A comparative multi-site and whole-body assessment of fascia in the horse and dog: a detailed histological investigation
Waqas Ahmed, Marta Kulikowska, Trine Ahlmann, Lise C Berg, Adrian P Harrison, Vibeke Sødring Elbrønd
This animal study compared the microscopic structure of fascia in horses and dogs across multiple body regions. Researchers found that horse fascia is generally tight and dense, while dog fascia is looser and more simil…
deep fascia; dog; histology; horse; hypodermis; myofascial kinetic lines; superficial fascia.
A
2019
Trigger Points, Pressure Pain Hyperalgesia, and Mechanosensitivity of Neural Tissue in Women with Chronic Pelvic Pain
Pedro Fuentes-Márquez, Marie Carmen Valenza, Irene Cabrera-Martos, Ana Ríos-Sánchez, Olga Ocón-Hernández
In this case-control study, researchers compared women with chronic pelvic pain to a healthy control group. They found that women with pelvic pain had significantly more myofascial trigger points in their low back, glut…
Myofascial Pain Syndrome; Pressure Algometry; Neurodynamics; Chronic Pelvic Pain
A++
2019
Ketogenic Diet and Microbiota: Friends or Enemies
Antonio Paoli, Laura Mancin, Antonino Bianco, Ewan Thomas, João Felipe Mota, Fabio Piccini
This narrative review explores the relationship between the very low-carbohydrate ketogenic diet (VLCKD) and the gut microbiota. The community of microbes in our gut is a dynamic entity known to play a fundamental role…
gut microbiota; gut microbiome; intestinal microbiome; ketogenic diet; ketogenic diet and fat
A+
2019
Anti-Inflammatory Diets and Fatigue
Ulrike Hass, Catrin Herpich, Kristina Norman
This narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…
anti-inflammatory nutrition; cancer; chronic fatigue; cytokines; fatigue reduction diet; inflammation; myalgic encephalomyelitis; omega-3 fatty acids; polyphenols; probiotics.
A+
2019
Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial
Patrick Jendricke, Christoph Centner, Denise Zdzieblik, Albert Gollhofer, Daniel König
This randomized controlled trial investigated the effects of combining resistance training with a daily intake of 15 grams of specific collagen peptides in premenopausal women. Over 12 weeks, participants trained three…
body composition; collagen peptides; hand-grip strength; leg press; premenopausal; protein supplementation; resistance training
A+++
2019
Future Aspects for Cannabinoids in Breast Cancer Therapy
Terézia Kisková, Felicitas Mungenast, Mária Suváková, Walter Jäger, Theresia Thalhammer
This scientific review explores how cannabinoids, such as THC and CBD, may influence breast cancer beyond their established role in palliative care for pain and nausea. Research suggests that cannabinoids might decelera…
CBD; Cannabis sativa; THC; breast cancer; cannabidiol; cannabinoid receptor; delta-9-tetrahydrocannabinol
A+++
2019
Cannabidiol differentially regulates basal and LPS-induced inflammatory responses in macrophages, lung epithelial cells, and fibroblasts
Thivanka Muthumalage, Irfan Rahman
This laboratory study investigated how cannabidiol (CBD) influences inflammatory responses in lung epithelial cells, fibroblasts, and immune cells. The researchers found that CBD can reduce inflammation triggered by ext…
CBD; E-cigarette; E-liquid; Lung; Marijuana; Vaping
A+++
2019
Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury
Enrico Sangiovanni, Marco Fumagalli, Barbara Pacchetti, Stefano Piazza, Andrea Magnavacca, Saba Khalilpour, Gloria Melz…
This in vitro study investigated how Cannabis sativa extract and its component cannabidiol (CBD) affect inflammation in human skin cells. Researchers found that both the extract and pure CBD reduced the release of sever…
Cannabis sativa L.; cannabidiol; fibroblasts; keratinocytes; skin inflammation; wound injury.
A+++
2019
New Insights of Uterine Leiomyoma Pathogenesis: Endocannabinoid System
Thangesweran Ayakannu, Anthony H Taylor, Timothy H Marczylo, Justin C Konje
This study investigated the role of the endocannabinoid system in the development of uterine leiomyomas, commonly known as fibroids. Researchers analyzed tissue samples and found that the expression of specific receptor…
CannabinoidsCannabinoid receptorsuterine myomfibroids
A
2019
Oral Collagen Supplementation: A Systematic Review of Dermatological Applications
Franchesca D Choi, Calvin T Sung, Margit L W Juhasz, Natasha Atanaskova Mesinkovsk
This systematic review examined eleven clinical trials investigating the impact of oral collagen supplements on skin health. The findings suggest that collagen hydrolysates and peptides may improve skin elasticity, hydr…
wound healingcollagenskin aging
A+++
2019
Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials
Juan Mario García-Coronado, Lorena Martínez-Olvera, Rodrigo E Elizondo-Omaña, Carlos Alberto Acosta-Olivo, Félix Vilche…
This meta-analysis of five randomized placebo-controlled trials evaluated the impact of oral collagen supplementation on osteoarthritis (OA) symptoms. The findings suggest that collagen may help reduce the overall disea…
Collagen supplementation; Meta-analysis; Osteoarthritis symptoms; Visual Analogue Scale; WOMAC index
A++
2019
Fascial organisation of motor synergies: a hypothesis
Alessandro Garofolini, Daris Svanera
This hypothesis paper explores how fascia helps organize movement through what are known as motor synergies. It suggests that instead of the brain controlling every muscle individually, the fascial system acts as a phys…
Motor control; degrees of freedom; movement coordination; muscle spindle; myofascial continuity.
A++
2019
A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
Liane Bolke, Gerrit Schlippe, Joachim Gerß, Werner Voss
This randomized, placebo-controlled study investigated the effects of a drinkable nutraceutical containing 2.5g of collagen peptides, vitamins, and minerals on skin health in women aged 35 and older. Over twelve weeks,…
aging; beauty; bioavailability; collagen peptides; corneometry; cutometry; high coverage [HC] collagen complex; wrinkles
A+++
2019
Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study
Toshio Mikami, Kohei Tano, Hosung Lee, Hyowon Lee, Jonghyuk Park, Fumiaki Ohta, Tyler W LeBaron, Shigeo Ohta
This randomized, double-blind, placebo-controlled study investigated the effects of drinking hydrogen-infused water (H2 water) before exercise. Across two experiments involving both untrained and trained participants on…
exercise; fatigue; hydrogen; hydrogen water
A++
2019
Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory
Ramesh C Gupta, Rajiv Lall, Ajay Srivastava, Anita Sinha
This narrative review explores hyaluronic acid (HA), a naturally occurring substance found in connective tissues and synovial fluid. HA is essential for joint lubrication and viscoelasticity, but its concentration and m…
hyaluronanwound healingHyaluronic acidosteoarthritiscancer therapy
A++
2019
Characterization of bony changes localized to the cervical articular processes in a mixed population of horses
Kevin K Haussler, Roy R Pool, Hilary M Clayton
This observational cross-sectional study characterized bony changes in the cervical articular processes of 55 horses without primary complaints of neck pain. The researchers found that 72% of the examined joints exhibit…
cervical processes
A++
2019
The Stomach’s Communication with Its Related Acupoints, and the “Intelligent Tissue” Hypothesis
Fletcher Kovich
This study explores the "intelligent tissue" hypothesis, which suggests that an organ's functional state is reflected in real-time at specific acupuncture points. By monitoring electrical impedance at six stomach-relate…
acupunctureimpedanceduodenalpacesetterslow wave
A+
2019
Effect of breakfast on weight and energy intake: systematic review and meta-analysis of randomised controlled trials
Katherine Sievert, Sultana Monira Hussain, Matthew J Page, Yuanyuan Wang, Harrison J Hughes, Mary Malek, Flavia M Cicut…
This systematic review and meta-analysis examined whether regular breakfast consumption affects body weight and energy intake in adults from high-income countries. The findings suggest that individuals who skipped break…
beakfastweight control
A+++
2019
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
Priya Rangan, Inyoung Choi, MinWei, Gerardo Navarrete, Esra Guen, Sebastian Brandhorst, Nobel Enyati, Gab Pasia, Daral…
This study investigates how cycles of a fasting-mimicking diet (FMD) affect inflammatory bowel disease (IBD) in both mice and humans. In animal models, FMD cycles reduced intestinal inflammation, encouraged the growth o…
Crohn’s disease; fasting; fasting-mimicking diet; gut microbiota; inflammation; inflammatory bowel disease; intermittent fasting; microbiome; ulcerative colitis
A+++
2019
Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease
Eirini Dimidi, Selina Rose Cox, Megan Rossi, Kevin Whelan
This narrative review examines how fermented foods such as kefir, kombucha, and sourdough bread affect gut health and the microbiota. The authors describe how the fermentation process creates bioactive compounds and pot…
fermented food; kefir; kimchi; kombucha; miso; natto; sauerkraut; sourdough; soy; tempeh
A++
2018
Vitamin C – A new player in regulation of the cancer epigenome
Linn Gillberg, Andreas D Ørskov, Minmin Liu, Laurine B S Harsløf, Peter A Jones, Kirsten Grønbæk
This narrative review explores the emerging role of vitamin C in cancer treatment, particularly in relation to epigenetics. The authors note that vitamin C is crucial for enzymes that help regulate gene expression, and…
Ascorbic acid; Cancer treatment; Epigenetics; Hematological malignancies; Vitamin C
A+++
2018
Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse
Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun, Dieter Blottner
This animal study investigated how disuse affects deep fascia and bone, and whether vibration could counteract these effects. Researchers used a rat model where hindlimbs were unloaded for 21 days to simulate disuse, wh…
extracellular matrixcollagenBonedeep fasciaBiomechanics
A
2018
Fasciae of the musculoskeletal system: normal anatomy and MR patterns of involvement in autoimmune diseases
Thomas Kirchgesner, Xavier Demondion, Maria Stoenoiu, Patrick Durez, Adrien Nzeusseu Toukap, Frédéric Houssiau, Christi…
This review article describes the fascial system as a three-dimensional continuum of connective tissue found throughout the body. The authors review the normal anatomy of fascia and its appearance on magnetic resonance…
fasciaMusculoskeletalAnatomyAutoimmuneMRI
A++
2018
Ascorbic acid in cancer treatment: let the phoenix fly
Niraj Shenoy, Edward Creagan, Thomas Witzig, Mark Levine
This review article discusses the renewed interest in Vitamin C (ascorbic acid) as a potential anti-cancer agent. When administered intravenously, Vitamin C can reach much higher concentrations in the body than when tak…
cancerVitamin Cascorbatepharmacokinetics
A+++
2018
Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement
Martina Zügel, Constantinos N Maganaris, Jan Wilke, Karin Jurkat-Rott, Werner Klingler, Scott C Wearing, Thomas Findley…
This consensus statement reviews the current state of knowledge on fascial tissue in sports medicine. It describes fascia as a body-wide network of connective tissue that integrates all body systems and is crucial for m…
fasciainjurysports medicine
A++
2018
Assessment of pain quality reveals distinct differences between nociceptive innervation of low back fascia and muscle in humans
Andreas Schilder, Walter Magerl, Thomas Klein, Rolf-Detlef Treede
This study explored whether pain from low back muscles is perceived differently than pain from the overlying fascia. Researchers used electrical stimulation in 16 healthy participants, who then described the induced pai…
Thoracolumbar fasciamultifidus musclePain qualityElectrical stimulationVerbal descriptors
A+++
2018
Structure and Distribution of an Unrecognized Interstitium in Human Tissues
Petros C Benias, Rebecca G Wells, Bridget Sackey-Aboagye, Heather Klavan, Jason Reidy, Darren Buonocore, Markus Miranda…
Using a new imaging technique, researchers identified a previously unrecognized, fluid-filled structure within the body's connective tissues. This network of collagen bundles and fluid-filled spaces, which they term the…
interstitiuminterstitial spacesfascia fluid
A
2018
Effectiveness of Physiotherapy Treatment for Urinary Incontinence in Women: A Systematic Review
Remedios López-Liria, María de los Ángeles Varverde-Martínez, David Padilla-Góngora, Patricia Rocamora-Pérez
This systematic review evaluated the effectiveness of different physiotherapy techniques for treating urinary incontinence in women. Researchers analyzed 16 studies covering methods such as pelvic floor exercises, vagin…
physiotherapywomenurinary incontinencepelvic floor muscle
1A+
2018
The Equine Hindlimb Proximal Suspensory Ligament: an Assessment of Health and Function by Means of Its Damping Harmonic Oscillator Properties, Measured Using an Acoustic Myography System: a New Modality Study
Jillian Costello Chavers, A Kent Allen, Waqas Ahmed, Lene Høeg Fuglsang-Damgaard, Adrian P Harrison
This study in horses explored a new method called acoustic myography (AMG) to help diagnose injuries in the proximal suspensory ligament (PSL) of the hindlimb. Researchers used a device to record sound signals from the…
equineCUROAcoustic myographySuspensory desmitisLameness
1A+
2018
Equine Manual Therapies in Sport Horse Practice
Kevin K Haussler
Manual therapies can provide diagnostic and therapeutic approaches for assessing and managing neuromuscular coordination and strength in sport horses. This review describes various techniques, including active and passi…
osteopathyManual Therapyproprioceptionmassage therapyNeuromuscular control
A+++
2018
Anatomical and Functional Relationships Between External Abdominal Oblique Muscle and Posterior Layer of Thoracolumbar Fascia
Chenglei Fan, Caterina Fede, Nathaly Gaudreault, Andrea Porzionato, Veronica Macchi, Raffaele de Caro, Carla Stecco
This study investigated the anatomical connection between the external abdominal oblique muscle (EO) and the thoracolumbar fascia (TLF) in the low back. Using both cadaveric dissection and CT scans, researchers found a…
external abdominal oblique muscle; fascia; lumbar; computed tomography
A+++
2018
Depression and anxiety in patients with chronic heart failure
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice Sacconi
In this review article, the authors discuss the connection between chronic heart failure (CHF), mental health, and diaphragm function. CHF is a serious, progressive condition often accompanied by depression and anxiety.…
anxiety • baroreceptors • chronic heart failure • diaphragm • depression • inflammatory cytokines • phrenic nerve • psychiatric disorders • rehabilitation • vagus nerve
1A+++
2018
Quantification of hyaluronan in human fasciae: variations with function and anatomical site
Caterina Fede, A Angelini, R Stern, V Macchi, A Porzionato, P Ruggieri, R De Caro, Carla Stecco
This study quantified for the first time the amount of hyaluronan (HA), a key lubricant, in human fascia from different parts of the body. Since HA is essential for the smooth gliding between fascial layers, understandi…
densification; extracellular matrix; fascia; fibrosis; gliding; hyaluronan; myofascial pain
A++
2018
Biotensegrity-Anatomy for the 21st Century Informing Yoga and Physiotherapy Concerning New Findings in Fascia Research
John Sharkey
This short article discusses how a new view of anatomy, called biotensegrity, is changing our understanding of the human body. This perspective focuses on fascia as a continuous, interconnected network that creates a un…
biotensegrityyogahuman anatomy
A
2018
The influence of breathing on the central nervous system
Bruno Bordoni, Shahin Purgol, Annalisa Bizzarri, Maddalena Modica, Bruno Morabito
This narrative review explores the diaphragm's extensive influence on the central nervous system. The authors discuss how the rhythm of our breath can physically move the brain, alter patterns of neural oscillation, and…
diaphragmbreathingphrenic nervevagus nerveneural oscillation
A
2018
Neuroinflammation and central sensitization in chronic and widespread pain
Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William Maixner
Chronic pain is partly maintained by central sensitization, a state where the nervous system becomes hypersensitive. This review discusses how neuroinflammation—inflammation in the nervous system—contributes to this pro…
inflammationchronic paainneuroinflammationsensitization
A
2018
The anatomical relationships of the tongue with the body system
Bruno Bordoni, Bruno Morabito, Roberto Mitrano, Marta Simonelli, Anastasia Toccafondi
In this review article, the authors examine the tongue's functions and its anatomical connections to the rest of the body. The tongue is not only essential for swallowing, breathing, and speaking, but it also affects po…
fasciadiaphragmphysiotherapytonguespeech therapy
A
2018
Frontiers in fascia research
Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…
This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…
fasciaultrasound.Pain therapySport sciencesIndentometry
A
2018
Effectiveness of 3-dimensional shoulder ultrasound in the diagnosis of rotator cuff tears
Aiping Teng, Fanxiao Liu, Dongsheng Zhou, Tao He, Yan Chevalier, Roland M Klar
In this meta-analysis, researchers combined data from seven studies involving 282 patients to evaluate the effectiveness of 3-dimensional (3D) ultrasound in diagnosing rotator cuff tears. The analysis found that 3D ultr…
3-dimensional ultrasounddiagnostic valuemeta-analysisrotator cuff tears
A++
2018
Emerging Therapies for Spastic Movement Disorders
Preeti Raghavan
Spasticity following a central nervous system injury can cause muscle stiffness, partly due to secondary changes in muscles and connective tissue. The 'hyaluronan hypothesis' suggests that an accumulation of hyaluronan,…
Spasticity; Muscle stiffness; Peripheral mechanism; Stroke; Brain Injury; Hyaluronidase; Hyaluronic Acid; Hyaluronan hypothesis
A
2018
A fundamental critique of the fascial distortion model and its application in clinical practice
Christoph Thalhamer
This narrative review critiques the Fascial Distortion Model (FDM), a manual therapy approach based on the idea that all musculoskeletal complaints stem from distortions of fascia. The author investigated the scientific…
Manual Therapyfasciaefascial distortion modelreductionismtypaldos
1A+
2018
The Fasciacytes- A New Cell Devoted To Fascial Gliding Regulation
Carla Stecco, Caterina Fede, Veronica Macchi, Andrea Porzionato, Lucia Petrelli, Carlo Biz, Robert Stern, Raffaele De C…
Researchers have identified a new type of cell within fascia, which they have named "fasciacytes." This study presents evidence that these specialized cells are responsible for producing hyaluronan, a key component of t…
hyaluronanfasciafasciacytesextracellular matrix
A+++
2018
Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability
Patrick Dressler, Dominic Gehring, Denise Zdzieblik, Steffen Oesser, Albert Gollhofer, Daniel König
This randomized, placebo-controlled study investigated the effect of specific collagen peptides on athletes with chronic ankle instability (CAI). Fifty athletes received either a daily collagen supplement or a placebo f…
collagennutritionAnkle sprainligaments
A
2018
The myodural bridges’ existence in the sperm whale
Pei Liu, Chan Li, Nan Zheng, Xiaoying Yuan, Yutong Zhou, Pu Chun, Yanyan Chi, Campbell Gilmore, Shengbo Yu, Hongjin Sui
In this anatomical animal study, researchers examined tissue from a sperm whale to see if it possessed a myodural bridge, a connection between the neck muscles and the dura mater previously identified in humans. The inv…
Myodural Bridge
A+++
2018
Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury
Thomas F Corbiere, Eileen M Weinheimer-Haus, Stefan Judex, Timothy J Koh
In this animal study, researchers investigated if low-intensity vibration (LIV) could improve healing of lacerated calf muscles in mice. The mice were divided into groups that received daily vibration treatment and a co…
skeletal muscle injury; laceration; low-intensity vibration; muscle regeneration; fibrosis
A++
2018
Low intensity vibration increases cartilage thickness in obese mice
Tee Pamon, Vincent Bhandal, Benjamin J Adler, M Ete Chan, Clinton T Rubin
This animal study investigated if a high-fat diet affected cartilage thickness in mice and if low-intensity vibration (LIV) could offer protection. Contrary to expectations, the high-fat diet alone did not significantly…
osteoarthritis; chondrocytes; exercise; biomechanics; adaptation; stem cell
A
2018
The myodural bridge in the common rock pigeon (Columbia livia): Morphology and possible physiological implications
Chukwuemeka Samuel Okoye, Nan Zheng, Sheng-Bo Yu, Hong-Jin Sui
In this anatomical study on pigeons, researchers investigated a connective tissue structure called the myodural bridge. Through dissections and tissue analysis of the suboccipital region where the skull meets the neck,…
Connective tissuecerebrospinal fluiddura materbirdhistological sections
A
2018
Orientation and property of fibers of the myodural bridge in humans
Nan Zheng, Yan-Yan Chi, Xiao-Han Yang, Nan-Xing Wang, Yi-Lin Li, Yang-Yang Ge, Lan-Xin Zhang, Tai-Yuan Liu, Xiao-Ying Y…
The myodural bridge is a fibrous connection between the deep suboccipital muscles of the neck and the spinal dura mater, the tough outer covering of the spinal cord. In this anatomical study, researchers investigated th…
Atlanto-axial interspace; Atlanto-occipital interspace; Collagen I fibers; Histologic staining; Myodural bridge; Suboccipital muscles; Vertebral dural ligament
A+++
2018
Resveratrol: A Double-Edged Sword in Health Benefits
Bahare Salehi, Abhay Prakash Mishra, Manisha Nigam, Bilge Sener, Mehtap Kilic, Mehdi Sharifi-Rad, Patrick Valere Tsouh…
This narrative review explores resveratrol, a natural polyphenol found in grape skins, red wine, and various plants. Research suggests that this compound possesses significant antioxidant, anti-inflammatory, and cardiop…
anticancer; antimicrobial; antioxidant; pharmacological activity; physiological effects; resveratrol.

Research.

An extravascular fluid transport system based on structural framework of fibrous connective tissues in human body

Active interfacial dynamic transport of fluid in a network of fibrous connective tissues throughout the whole body

Acute Effects of Static Stretching on Muscle Strength and Power: An Attempt to Clarify Previous Caveats

Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients

Bone Broth Unlikely to Provide Reliable Concentrations of Collagen Precursors Compared With Supplemental Sources of Collagen Used in Collagen Research

Mitochondrial superoxide anions induced by exogenous oxidative stress determine tumor cell fate: an individual cell-based study

Ultrasound-detected connective tissue involvement in acute muscle injuries in elite athletes and return to play: The French National Institute of Sports (INSEP) study

Hierarchical Hydrogel Composite Interfaces with Robust Mechanical Properties for Biomedical Applications

Association of thoraco-lumbar fascia length in individuals with non-specific low back pain - an observational study

Structural Gender Dimorphism and the Biomechanics of the Gluteal Subcutaneous Tissue: Implications for the Pathophysiology of Cellulite

Collagenase Clostridium Histolyticum for the Treatment of Edematous Fibrosclerotic Panniculopathy (Cellulite): A Randomized Trial

A comparative multi-site and whole-body assessment of fascia in the horse and dog: a detailed histological investigation

Trigger Points, Pressure Pain Hyperalgesia, and Mechanosensitivity of Neural Tissue in Women with Chronic Pelvic Pain

Ketogenic Diet and Microbiota: Friends or Enemies

Anti-Inflammatory Diets and Fatigue

Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial

Future Aspects for Cannabinoids in Breast Cancer Therapy

Cannabidiol differentially regulates basal and LPS-induced inflammatory responses in macrophages, lung epithelial cells, and fibroblasts

Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury

New Insights of Uterine Leiomyoma Pathogenesis: Endocannabinoid System

Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials

Fascial organisation of motor synergies: a hypothesis

A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study

Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study

Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory

Characterization of bony changes localized to the cervical articular processes in a mixed population of horses

The Stomach’s Communication with Its Related Acupoints, and the “Intelligent Tissue” Hypothesis

Effect of breakfast on weight and energy intake: systematic review and meta-analysis of randomised controlled trials

Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology

Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease

Vitamin C – A new player in regulation of the cancer epigenome

Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse

Fasciae of the musculoskeletal system: normal anatomy and MR patterns of involvement in autoimmune diseases

Ascorbic acid in cancer treatment: let the phoenix fly

Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement

Assessment of pain quality reveals distinct differences between nociceptive innervation of low back fascia and muscle in humans

Structure and Distribution of an Unrecognized Interstitium in Human Tissues

Effectiveness of Physiotherapy Treatment for Urinary Incontinence in Women: A Systematic Review

The Equine Hindlimb Proximal Suspensory Ligament: an Assessment of Health and Function by Means of Its Damping Harmonic Oscillator Properties, Measured Using an Acoustic Myography System: a New Modality Study

Equine Manual Therapies in Sport Horse Practice

Anatomical and Functional Relationships Between External Abdominal Oblique Muscle and Posterior Layer of Thoracolumbar Fascia

Depression and anxiety in patients with chronic heart failure

Quantification of hyaluronan in human fasciae: variations with function and anatomical site

Biotensegrity-Anatomy for the 21st Century Informing Yoga and Physiotherapy Concerning New Findings in Fascia Research

The influence of breathing on the central nervous system

Neuroinflammation and central sensitization in chronic and widespread pain

The anatomical relationships of the tongue with the body system

Frontiers in fascia research

Effectiveness of 3-dimensional shoulder ultrasound in the diagnosis of rotator cuff tears

Emerging Therapies for Spastic Movement Disorders

A fundamental critique of the fascial distortion model and its application in clinical practice

The Fasciacytes- A New Cell Devoted To Fascial Gliding Regulation

Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability

The myodural bridges’ existence in the sperm whale

Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury

Low intensity vibration increases cartilage thickness in obese mice

The myodural bridge in the common rock pigeon (Columbia livia): Morphology and possible physiological implications

Orientation and property of fibers of the myodural bridge in humans

Resveratrol: A Double-Edged Sword in Health Benefits