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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
Showing 361–420 of 954 studies · page 7/16Since 2010With summary
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  1. A++
    2019

    Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats

    Marta Toral, Iñaki Robles Vera, Néstor de la Visitación, Miguel Romero, Manuel Sánchez, Manuel Gómez Guzmán, Alba Rodri…

    This animal study investigated the link between gut bacteria, the immune system, and blood pressure in rats. Researchers transplanted gut microbiota between spontaneously hypertensive rats and rats with normal blood pre…

    hypertensionendothelial dysfunctiongut dysbiosisimmune cells
  2. A++
    2019

    Fascial Entrapment Neuropathy

    ANTONIO STECCO, CARMELO PIRRI, CARLA STECCO

    This narrative review explores how fascia can contribute to nerve entrapment syndromes, which cause pain, sensory abnormalities, and weakness. The authors describe how nerves are surrounded by a microenvironment of conn…

    nerve; nerve entrapment; fascia; Parsonage-Turner
  3. A
    2019

    High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition

    Ling-Hui Zeng, Qing-Mei Wang, Lin-Yi Feng, Yu-Dun Ke, Qian-Zi Xu, An-Yi Wei, Chong Zhang, Rong-Biao Ying

    This study on breast cancer cells in the lab and in mice explored how different doses of vitamin C affect cancer cell behavior. Researchers found that low and medium doses of vitamin C seemed to encourage cancer cells t…

    Breast cancermetastasisTGF-β1Vitamin C
  4. A
    2019

    Innervation of the thoracolumbar fascia

    Siegfried Mense

    This study, conducted primarily on rats, investigated the types of nerves in the thoracolumbar fascia (TLF) to better understand its sensory roles. Researchers found only free nerve endings, many of which are associated…

    NociceptionThoracolumbar fasciainnervationfree nerve endingsproprioception
  5. A
    2019

    Association of thoraco-lumbar fascia length in individuals with non-specific low back pain - an observational study

    Shellette D' Almeida, Charu Eapen, Shyam Krishnan

    This observational study compared 31 people with non-specific low back pain to 31 healthy individuals to investigate the thoracolumbar fascia (TLF). Researchers measured TLF length by assessing lumbar spine rotation, an…

    low back painthoracolumar fascia lenght
  6. A++
    2019

    Characterization of bony changes localized to the cervical articular processes in a mixed population of horses

    Kevin K Haussler, Roy R Pool, Hilary M Clayton

    This observational cross-sectional study characterized bony changes in the cervical articular processes of 55 horses without primary complaints of neck pain. The researchers found that 72% of the examined joints exhibit…

    cervical processes
  7. A++
    2019

    The Stomach’s Communication with Its Related Acupoints, and the “Intelligent Tissue” Hypothesis

    Fletcher Kovich

    This study explores the "intelligent tissue" hypothesis, which suggests that an organ's functional state is reflected in real-time at specific acupuncture points. By monitoring electrical impedance at six stomach-relate…

    acupunctureimpedanceduodenalpacesetterslow wave
  8. A+
    2019

    Effect of breakfast on weight and energy intake: systematic review and meta-analysis of randomised controlled trials

    Katherine Sievert, Sultana Monira Hussain, Matthew J Page, Yuanyuan Wang, Harrison J Hughes, Mary Malek, Flavia M Cicut…

    This systematic review and meta-analysis examined whether regular breakfast consumption affects body weight and energy intake in adults from high-income countries. The findings suggest that individuals who skipped break…

    beakfastweight control
  9. A
    2019

    Role of matrix metalloproteinases 2 and 9 in the development of frozen shoulder: human data and experimental analysis in a rat contracture model

    Chul-Hyun Cho, Yun-Mee Lho, Ilseon Hwang, Du Hwan Kim

    This study investigated the biological processes behind frozen shoulder, a condition characterized by pain and stiffness. Researchers analyzed joint capsule tissue from both patients with frozen shoulder and from a rat…

    inflammationfibrosisfrozen shoulderimmobilizationrat; matrix metalloproteinases
  10. A
    2019

    Adhesive capsulitis: MRI correlation with clinical stages and proposal of MRI staging

    Amarnath Chellathurai, Komalavalli Subbiah, Atchaya Elangovan,, Sivakumar Kannappan

    This study investigated whether magnetic resonance imaging (MRI) findings can reflect the clinical stages of adhesive capsulitis, also known as frozen shoulder. Researchers analyzed MRIs from 74 patients, looking for sp…

    Adhesive capsulitis; MRI staging; magnetic resonance imaging; frozen shoulder
  11. A
    2019

    Distinct fibroblast subsets drive inflammation and damage in arthritis

    Adam P Croft, Joana Campos, Kathrin Jansen, Jason D Turner, Jennifer Marshall, Moustafa Attar, Loriane Savary, Corinna…

    This study in mice investigated the role of fibroblasts, a type of connective tissue cell, in arthritis. Researchers identified two distinct subsets of fibroblasts with different functions. One type, located in the syno…

    Synovial fibroblasts; inflammation; arthritis; transcriptomics; rheumatoid arthritis
  12. A++
    2019

    8 natural supplements to help fight inflammation

    Zawn Villines

    Inflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…

    inflammationomega-3curcumin
  13. A
    2019

    Fascia thickness, aging and flexibility: is there an association?

    Jan Wilke, Veronica Macchi, Raffaele De Caro, Carla Stecco

    This study investigated how deep fascia thickness relates to age and flexibility in healthy women. Researchers compared a group of young women with a group of older women, using ultrasound to measure fascia thickness an…

    connective tissue; hyaluronic acid; stiffness; myofascial; aging
  14. A
    2019

    Benefits of adding stretching to a moderate-intensity aerobic exercise programme in women with fibromyalgia: a randomized controlled trial

    Miguel Gómez-Hernández, Tomás Gallego-Izquierdo, Patricia Martínez-Merinero, Daniel Pecos-Martín, Alejandro Ferragut-Ga…

    This randomized controlled trial investigated whether adding stretching to a moderate-intensity aerobic exercise program provided extra benefits for women with fibromyalgia. One group performed moderate aerobic exercise…

    FibromyalgiaStretchingpainsleep qualityquality of life
  15. A
    2019

    Chronic low back pain influences trunk neuromuscular control during unstable sitting among persons with lower-limb loss

    Courtney M Butowicz, Julian C Acasio, Silfies Sheri P, Maury A Nussbaum, Brad D Hendershot

    People with lower-limb loss are at a higher risk for chronic low back pain. This study investigated whether trunk postural control differs between those with and without pain in this population. Researchers had men with…

    low back painBiomechanicsPostural controlAmputation
  16. C
    2019

    Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models

    Anne-Laure Papa, Amanda Jiang, Netanel Korin, Michelle B Chen, Erin T Langan, Anna Waterhouse, Emma Nash, Jildaz Carof,…

    Platelets are crucial for blood clotting but can also contribute to thrombosis and cancer metastasis. In this preclinical study, researchers created modified human platelets, called "platelet decoys," that retained thei…

    Plateletplatelet decoystrombosismetastatic tumors
  17. B
    2019

    Anatomy, Bony Pelvis and Lower Limb, Pelvic Fascia

    Marco A Siccardi, Cristina Valle

    This anatomical review describes the pelvis not as a rigid, static base, but as a dynamic structure. Applying a biotensegrity model, the authors explain how the pelvic bones are suspended within a complex web of tension…

    Pelvispelvic fascia
  18. B
    2019

    Modeling and simulation of musculoskeletal system of human lower limb based on tensegrity structure

    Zhanxi Wang, Chaoran Yang, Kang Feng, Xiansheng Qin

    Researchers created a computer model of the human lower limb's musculoskeletal system using tensegrity principles, which balance tension and compression. Using an established muscle model (the Hill model), they simulate…

    Tensegrity structure; lower limb model; motion analysis; gait simulation
  19. A+
    2019

    Collagen changes in pelvic support tissues in women with pelvic organ prolapse

    Runqi Gong, Zhijun Xia

    This narrative review summarizes research on how changes in collagen are linked to pelvic organ prolapse in women. Collagen is a critical component of the pelvic floor, providing essential supportive functions. Studies…

    extracellular matrixcollagenBiomechanicsPelvic organ prolapseSignaling pathways
  20. B
    2019

    Blocking around the transversalis fascia: behind the scene

    Francesco Vasques, Carla Stecco, Raffaele Mitri, Raffaele De Caro, Pierfrancesco Fusco, Astrid U Behr

    This cadaver study investigated the anatomy of the transversalis fascia, a thin layer of connective tissue in the abdominal wall, to understand its role in certain nerve blocks. Through dissection and microscopic analys…

    Nerve block - abdominal wallanatomy and histology - Fascia.
  21. A+
    2019

    Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial

    Patrick Jendricke, Christoph Centner, Denise Zdzieblik, Albert Gollhofer, Daniel König

    This randomized controlled trial investigated the effects of combining resistance training with a daily intake of 15 grams of specific collagen peptides in premenopausal women. Over 12 weeks, participants trained three…

    body composition; collagen peptides; hand-grip strength; leg press; premenopausal; protein supplementation; resistance training
  22. C
    2019

    Modelling Cell Origami via a Tensegrity Model of the Cytoskeleton in Adherent Cells

    Lili Wang, Weiyi Chen

    Researchers created a computer model to better understand "cell origami," a technique where the natural pulling forces of cells are used to fold tiny structures. This model represents the cell's internal framework, or c…

    Tensegritycytoskeletoncell adhesioncell origami
  23. A
    2019

    Where is your head? Perception of relative position of the head on a wielded object

    Jeffrey B Wagman, Takahiro Higuchi

    This study explored how we perceive our body's position relative to an object we are holding or balancing. Researchers specifically tested this by having participants "wield" an object with their head, a body part not t…

    Haptics . Perception and action . Touch
  24. A++
    2019

    Role of fasciae around the median nerve in pathogenesis of carpal tunnel syndrome: microscopic and ultrasound study

    Carla Stecco, Federico Giordani, Chenglei Fan, Carlo Biz, Carmelo Pirri, Anna Chiara Frigo, Caterina Fede, Veronica Mac…

    This study investigated the connection between the median nerve and its surrounding fascia in carpal tunnel syndrome. Using microscopic analysis of tissue samples and ultrasound imaging of both healthy subjects and pati…

    carpal tunnel syndrome; double crush syndrome; fasciae; median nerve; paraneural sheath; ultrasound.
  25. A
    2019

    Biotensegrity or Fascintegrity

    Bruno Bordoni, Matthew A Varacallo, Bruno Morabito, Marta Simonelli

    In this theoretical review, the authors question the popular "biotensegrity" model for describing the body's mechanics. They argue the model is incomplete because it fails to account for crucial factors like bodily flui…

    fasciaMyofascialOsteopathicphysiotherapyskeletal muscle
  26. 1A+
    2019

    Bone Tissue is an Integral Part of the Fascial System

    Bruno Bordoni, Maria Marcella Lagana

    This review article proposes that bone tissue should be considered an integral part of the fascial system, a departure from the current definition. The authors support this by highlighting the shared embryological origi…

    fasciaBonefascial systemMyofascial
  27. A
    2019

    Myofascial Chains of the Upper Limb: A Systematic Review of Anatomical Studies

    JAN WILKE, FRIEDER KRAUSE

    This systematic review compiled research to determine if myofascial chains, previously identified in the trunk and lower limbs, also exist in the upper limb. Analyzing 13 anatomical dissection studies, the authors found…

    continuity; fascia; force transmission; muscles; cadavers; connective tissue; myofascial chains
  28. A+++
    2019

    Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study

    Toshio Mikami, Kohei Tano, Hosung Lee, Hyowon Lee, Jonghyuk Park, Fumiaki Ohta, Tyler W LeBaron, Shigeo Ohta

    This randomized, double-blind, placebo-controlled study investigated the effects of drinking hydrogen-infused water (H2 water) before exercise. Across two experiments involving both untrained and trained participants on…

    exercise; fatigue; hydrogen; hydrogen water
  29. A+++
    2019

    Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology

    Priya Rangan, Inyoung Choi, MinWei, Gerardo Navarrete, Esra Guen, Sebastian Brandhorst, Nobel Enyati, Gab Pasia, Daral…

    This study investigates how cycles of a fasting-mimicking diet (FMD) affect inflammatory bowel disease (IBD) in both mice and humans. In animal models, FMD cycles reduced intestinal inflammation, encouraged the growth o…

    Crohn’s disease; fasting; fasting-mimicking diet; gut microbiota; inflammation; inflammatory bowel disease; intermittent fasting; microbiome; ulcerative colitis
  30. B
    2018

    Global Expression Profiling Identifies a Novel Hyaluronan Synthases 2 Gene in the Pathogenesis of Lower Extremity Varicose Veins

    Chia-Shan Hsieh, Chia-Ti Tsai, Yau-Hung Chen, Sheng-Nan Chang, Juey-Jen Hwang, Eric Y Chuang, I-HuiWu

    Researchers investigated the genetic factors behind varicose veins by comparing vein tissue from patients with and without the condition. They found that the gene hyaluronan synthase 2 (HAS2) was significantly less acti…

    varicose veins; HAS2; RNA seq
  31. A
    2018

    New Proposal to Define the Fascial System

    Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto Castagna, Beatrice Sacconi, Paul Mazzucco

    In this proposal, the authors suggest a new definition for the fascial system, noting that a universally accepted one does not yet exist. They argue for including the epidermis (the outer layer of skin) based on functio…

    fasciaConnective tissuefibroblastMyofascialSkin
  32. A+++
    2018

    Effect of Health-Promoting Agents on Exclusion-Zone Size

    Abha Sharma, Colby Adams, Benjamin D Cashdollar, Zheng Li, Nam V Nguyen, Himasri Sai, Jiachun Shi, Gautham Velchuru, Ke…

    This experimental study investigated how various health-promoting agents affect the formation of "exclusion zone" (EZ) water, often referred to as the fourth phase of water. Researchers found that substances such as hol…

    dose dependent; dose response; exclusion zone water; health-promoting agents; hydrophilic surface; nutraceuticals
  33. A+
    2018

    Negative Air Ions and Their Effects on Human Health and Air Quality Improvement

    Shu-Ye Jiang, Ali Ma, Srinivasan Ramachandran

    This review paper examines the research on negative air ions (NAIs) and their effects on human health and air quality. Used for over a century in air cleaning, NAIs are associated with improved psychological health and…

    negative air ions; superoxide; particulate matter; pulsed electric field
  34. A
    2018

    Metabolic acidosis and the role of unmeasured anions in critical illness and injury

    Tobias Zingg, Bishwajit Bhattacharya, Linda L Maerz

    In this review article, the authors discuss metabolic acidosis, a common condition in critically ill patients that is associated with increased mortality. A significant component of this acidosis can be caused by so-cal…

    Metabolic acidosisUnmeasured anionsStrong ion differenceStrong ion gapAnion gap Base excess
  35. A++
    2018

    Release of fascial compartment boundaries reduces muscle force output

    Roy J Ruttiman, David A Sleboda,, Thomas J Roberts

    In this animal study, researchers investigated how the fascial sheets that enclose muscles affect their function. They surgically removed the fascia from a wing muscle in wild turkeys to see how it changed the muscle's…

    Muscletendoncompartmentfasciotomyintramuscular pressure
  36. A+++
    2018

    Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse

    Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun, Dieter Blottner

    This animal study investigated how disuse affects deep fascia and bone, and whether vibration could counteract these effects. Researchers used a rat model where hindlimbs were unloaded for 21 days to simulate disuse, wh…

    extracellular matrixcollagenBonedeep fasciaBiomechanics
  37. A
    2018

    Variations in Contents of Hyaluronan in the Peritumoral Micro-Environment of Human Chondrosarcoma

    Caterina Fede, Carla Stecco, Andrea Angelini, Chenglei Fan, Elisa Belluzzi, Assunta Pozzuoli, Pietro Ruggieri, Raffaele…

    The micro-environment surrounding a tumor greatly influences its growth and response to therapy. This study focused on chondrosarcoma, a type of bone cancer resistant to both chemotherapy and radiation. Researchers quan…

    hyaluronan; chondrosarcoma; peritumoral stroma; fascia; tumor micro-environment; malignant bone tumor; grade
  38. A
    2018

    Immediate effects of self-myofascial release on latent trigger point sensitivity: a randomized, placebo-controlled trial

    Jan Wilke, Lutz Vogt, Winfried Banzer

    This randomized, placebo-controlled trial examined whether foam rolling could immediately reduce sensitivity in latent trigger points. Researchers compared 90 seconds of static compression, dynamic rolling, and a placeb…

    fasciaMyofascial painFoam rollingSelf-masage
  39. A++
    2018

    Subcutaneous adipose tissue therapy reduces fat by dual X-ray absorptiometry scan and improves tissue structure by ultrasound in women with lipoedema and Dercum disease

    M Ibarra, A Eekema, C Ussery, D Neuhardt, K Garby, K L Herbst

    This small study investigated a non-surgical therapy for subcutaneous adipose tissue in seven women with lipoedema or Dercum disease. Over four weeks of treatment, participants experienced significant reductions in weig…

    lipoedemaDercum diseasesubcutaneous adipose tissue.
  40. A
    2018

    Lipedema—An update

    Uwe Wollina

    This review provides an update on lipedema, a chronic condition affecting subcutaneous fat tissue in the limbs, almost exclusively in women. It typically appears during or after puberty and is characterized by symmetric…

    painEdemaobesitylipedemalymphedema
  41. A+++
    2018

    Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability

    Patrick Dressler, Dominic Gehring, Denise Zdzieblik, Steffen Oesser, Albert Gollhofer, Daniel König

    This randomized, placebo-controlled study investigated the effect of specific collagen peptides on athletes with chronic ankle instability (CAI). Fifty athletes received either a daily collagen supplement or a placebo f…

    collagennutritionAnkle sprainligaments
  42. A
    2018

    Comparison of vibration rolling, nonvibration rolling, and static stretching as a warm-up exercise on flexibility, joint proprioception, muscle strength, and balance in young adults

    Chia-Lun Lee, I-Hua Chu, Bo-Jhang Lyu, Wen-Dien Chang, Nai-Jen Chang

    This study compared the immediate effects of three warm-up techniques in young adults: vibration rolling, non-vibration rolling, and static stretching. Researchers measured changes in lower-body flexibility, joint posit…

    Vibration; self-myofascial release; foam rolling; exercise; performance
  43. C
    2018

    Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners?

    Katarzyna Pietraszek-Gremplewicz, Konstantina Karamanou, Aïchata Niang, Manuel Dauchez, Nicolas Belloy, François-Xavier…

    This narrative review summarizes research on a family of proteins called small leucine-rich proteoglycans (SLRPs). These proteins are important regulators of the extracellular matrix and have been identified as potentia…

    fibromodulinSLRPsLumicanDecorinBiglycan
  44. A
    2018

    Fascial well-being: Mechanotransduction in manual and movement therapies

    Leon Chaitow

    This article discusses mechanotransduction, the process by which cells in connective tissue sense and respond to mechanical forces like stretch, compression, and shear. Specialized cells such as fibroblasts communicate…

    mechanotransduction
  45. A++
    2018

    Emerging Therapies for Spastic Movement Disorders

    Preeti Raghavan

    Spasticity following a central nervous system injury can cause muscle stiffness, partly due to secondary changes in muscles and connective tissue. The 'hyaluronan hypothesis' suggests that an accumulation of hyaluronan,…

    Spasticity; Muscle stiffness; Peripheral mechanism; Stroke; Brain Injury; Hyaluronidase; Hyaluronic Acid; Hyaluronan hypothesis
  46. A+
    2018

    Endogenous systems involved in exercise-induced analgesia

    R DA SILVA SANTOS, G GALDINO

    This narrative review describes the phenomenon of exercise-induced analgesia, which is the pain-relieving effect of physical activity. Studied since the 1970s, this effect is seen in both endurance and resistance exerci…

    EndocannabinoidspainexerciseNitric oxideanalgesia
  47. 1A+
    2018

    From mechanobiology to developmentally inspired engineering

    Donald Ingber

    This review article, based on a lecture, explores the field of mechanobiology, which studies the central role of physical forces in development and physiology. The author reviews 40 years of his laboratory's foundationa…

    Tensegritymechanicalorgans-on-chipstissue engineering
  48. A+++
    2018

    Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis

    Jing Li

    This commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…

    meta-analysisVitamin CAscorbic acidsepsisSevere sepsis
  49. 1A+
    2018

    Equine Manual Therapies in Sport Horse Practice

    Kevin K Haussler

    Manual therapies can provide diagnostic and therapeutic approaches for assessing and managing neuromuscular coordination and strength in sport horses. This review describes various techniques, including active and passi…

    osteopathyManual Therapyproprioceptionmassage therapyNeuromuscular control
  50. A++
    2018

    Low-frequency vibrotherapy considerably improves the effectiveness of manual lymphatic drainage (MLD) in patients with lipedema: A two-armed, randomized, controlled pragmatic trial

    Rainer Schneider

    This randomized controlled trial investigated the effect of adding low-frequency vibrotherapy to manual lymphatic drainage (MLD) for 30 women with stage 2–3 lipedema. Participants were randomly assigned to receive eithe…

    Lipedema; MLD; quality of life; shock wave vibrotherapy
  51. A++
    2018

    Bone is fascia

    Stephen Levin

    This entry, based on its title alone, proposes a conceptual link between bone and fascia. Without an abstract or full text, the specific arguments made by the author remain unclear. The title 'Bone is fascia' suggests a…

    fascia
  52. A+++
    2018

    Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study

    Do-Un Kim, Hee-Chul Chung, Jia Choi, Yasuo Sakai, Boo-Yong Lee

    This randomized, double-blind, placebo-controlled study evaluated the effects of daily low-molecular-weight collagen peptide (LMWCP) supplementation on the skin of 64 women. Over 12 weeks, researchers measured skin hydr…

    collagen hydrolysate; collagen tripeptide; fish collagen; low-molecular-weight collagen peptide; photoaging; skin elasticity; skin hydration; skin wrinkling; type I collagen.
  53. A
    2018

    The influence of breathing on the central nervous system

    Bruno Bordoni, Shahin Purgol, Annalisa Bizzarri, Maddalena Modica, Bruno Morabito

    This narrative review explores the diaphragm's extensive influence on the central nervous system. The authors discuss how the rhythm of our breath can physically move the brain, alter patterns of neural oscillation, and…

    diaphragmbreathingphrenic nervevagus nerveneural oscillation
  54. A
    2018

    Neuroinflammation and central sensitization in chronic and widespread pain

    Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William Maixner

    Chronic pain is partly maintained by central sensitization, a state where the nervous system becomes hypersensitive. This review discusses how neuroinflammation—inflammation in the nervous system—contributes to this pro…

    inflammationchronic paainneuroinflammationsensitization
  55. A++
    2018

    Ascorbic acid in cancer treatment: let the phoenix fly

    Niraj Shenoy, Edward Creagan, Thomas Witzig, Mark Levine

    This review article discusses the renewed interest in Vitamin C (ascorbic acid) as a potential anti-cancer agent. When administered intravenously, Vitamin C can reach much higher concentrations in the body than when tak…

    cancerVitamin Cascorbatepharmacokinetics
  56. 1A+++
    2018

    Quantification of hyaluronan in human fasciae: variations with function and anatomical site

    Caterina Fede, A Angelini, R Stern, V Macchi, A Porzionato, P Ruggieri, R De Caro, Carla Stecco

    This study quantified for the first time the amount of hyaluronan (HA), a key lubricant, in human fascia from different parts of the body. Since HA is essential for the smooth gliding between fascial layers, understandi…

    densification; extracellular matrix; fascia; fibrosis; gliding; hyaluronan; myofascial pain
  57. A
    2018

    The anatomical relationships of the tongue with the body system

    Bruno Bordoni, Bruno Morabito, Roberto Mitrano, Marta Simonelli, Anastasia Toccafondi

    In this review article, the authors examine the tongue's functions and its anatomical connections to the rest of the body. The tongue is not only essential for swallowing, breathing, and speaking, but it also affects po…

    fasciadiaphragmphysiotherapytonguespeech therapy
  58. A
    2018

    Meaning of the Solid and Liquid Fascia to Reconsider the Model of Biotensegrity

    Bruno Bordoni, David Lintonbon, Bruno Morabito

    This theoretical article proposes a reconsideration of the traditional biotensegrity model. The authors argue that fascia should be viewed as a system with both solid and liquid components, where blood and lymph constit…

    fasciaChiropracticManual TherapyMyofascialOsteopathic
  59. A
    2018

    Frontiers in fascia research

    Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…

    This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…

    fasciaultrasound.Pain therapySport sciencesIndentometry
  60. A
    2018

    Morphometric and dynamic measurements of muscular fascia in healthy individuals using ultrasound imaging: a!summary of the discrepancies and gaps in the current literature

    Caterina Fede, Nathaly Gaudreault, Chenglei Fan, Veronica Macchi, Raffaele De Caro, Carla Stecco

    This narrative review examined existing research on using ultrasound to measure muscular fascia in healthy people. The authors found that while ultrasound is a useful tool, the research is concentrated on a few specific…

    Fascia · Ultrasound imaging · Thickness · Strain · Motion