Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
- B2019
Anatomy, Bony Pelvis and Lower Limb, Pelvic Fascia
Marco A Siccardi, Cristina ValleThis anatomical review describes the pelvis not as a rigid, static base, but as a dynamic structure. Applying a biotensegrity model, the authors explain how the pelvic bones are suspended within a complex web of tension…
Pelvispelvic fascia - A+2019
Overuse Injury: The Result of Pathologically Altered Myofascial Force Transmission?
Jan Wilke, Andry Vleeming, Scott WearingIn this narrative review, the authors propose a new perspective on overuse injuries. Traditionally, therapy focuses on the site of pain, viewing the injury as the result of local, repetitive microdamage. The authors hyp…
Myofascial force transmissionoveruse injuryfascitismusculoskeletal disorder - A2019
Cellular nanoscale stiffness patterns governed by intracellular forces
Nicola Mandriota, Claudia Friedsam, John A Jones-Molina, Kathleen V Tatem, Donald E Ingber, Ozgur SahinCell stiffness is important in many biological processes, but its precise relationship to the forces acting inside the cell has been unclear. In this study, researchers developed a new high-resolution imaging platform t…
Tensegritymechanotransductioncell - cell interaction - A2019
Intra-articular effects of combined xenogenous serum rich in growth factors (SRGF) and vitamin C on histopathology grading and staging of osteoarthritis in rat model
S Azizi, A Farsinejad, R Kheirandish, H FatemiThis animal study investigated a potential treatment for osteoarthritis (OA) in rats. Researchers induced OA in the rats' knees and then treated them with intra-articular injections. One group received a combination of…
Osteoarthritis; SRGF; Monosodium iodoacetate; Vitamin C; Histopathology - A2019
Biophysics of Cell-Substrate Interactions Under Shear
Neha Paddillaya, Ashish Mishra, Paturu Kondaiah, Pramod Pullarkat, Gautam I Menon, Namrata GundiahIn this review article, the authors examine how cells adhere to surfaces and respond to mechanical forces. Cells use complex structures called focal adhesions to sense and react to their environment, including forces fr…
mechanotransductionfocal adhesionsstress fibersshear stress and devicesbiophysical models - A++2019
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
Alpha A Fowler, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday, Bernard Fisher, Leroy…This randomized controlled trial investigated whether intravenous vitamin C could help patients with sepsis and severe acute respiratory failure. Researchers gave 167 patients either a high-dose vitamin C infusion or a…
sepsisintravenous vitamin C - A++2019
The Stomach’s Communication with Its Related Acupoints, and the “Intelligent Tissue” Hypothesis
Fletcher KovichThis study explores the "intelligent tissue" hypothesis, which suggests that an organ's functional state is reflected in real-time at specific acupuncture points. By monitoring electrical impedance at six stomach-relate…
acupunctureimpedanceduodenalpacesetterslow wave - A++2019
Plasma Amino Acid Concentrations After the Ingestion of Dairy and Collagen Proteins, in Healthy Active Males
Rebekah D Alcock, Gregory C Shaw, Nicolin Tee, Louise M BurkeThis study investigated how blood amino acid levels changed in healthy, active men after they consumed either collagen or dairy proteins. Researchers found that the different protein sources led to distinct amino acid p…
Connective tissuetendonligamentprolineleucine - A2019
High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition
Ling-Hui Zeng, Qing-Mei Wang, Lin-Yi Feng, Yu-Dun Ke, Qian-Zi Xu, An-Yi Wei, Chong Zhang, Rong-Biao YingThis study on breast cancer cells in the lab and in mice explored how different doses of vitamin C affect cancer cell behavior. Researchers found that low and medium doses of vitamin C seemed to encourage cancer cells t…
Breast cancermetastasisTGF-β1Vitamin C - 1A+2019
The Awareness of the Fascial System
Bruno Bordoni, Marta SimonelliIn this theoretical article, the authors propose a new way of looking at the fascial system, drawing on concepts from quantum physics. They suggest that fascial cells can sense, remember, and even anticipate mechanical…
fasciafascial systemMyofascialquantum physicsphysiology - A+++2019
Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study
Toshio Mikami, Kohei Tano, Hosung Lee, Hyowon Lee, Jonghyuk Park, Fumiaki Ohta, Tyler W LeBaron, Shigeo OhtaThis randomized, double-blind, placebo-controlled study investigated the effects of drinking hydrogen-infused water (H2 water) before exercise. Across two experiments involving both untrained and trained participants on…
exercise; fatigue; hydrogen; hydrogen water - 1A+2019
The fascial breath
Bruno Bordoni, Marta Simonelli, Bruno MorabitoThis narrative review proposes a new way of understanding the diaphragm muscle, moving beyond a purely mechanical view. The authors argue that the diaphragm is not just covered by fascia but is fundamentally a fascial t…
fasciaMyofascialOsteopathicdiaphragmbreathing - A2019
Age-related changes in leg proprioception: implications for postural control
Mélanie Henry, Stéphane BaudryThis narrative review examines how aging affects proprioception—the body's sense of its own position and movement—and its implications for balance. To maintain an upright stance, the brain relies on signals from recepto…
proprioceptionmuscle spindlesbalanceIa afferentsupright standing - A2019
Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis
Tabea C Hornung, Hans-Konrad BiesalskiUnlike many animals, humans cannot produce their own vitamin C. This study explores a potential evolutionary advantage of this loss. Researchers compared red blood cells from humans and pigs (who can make vitamin C) and…
glucose transporter; vitamin C; gulono-lactone-oxidase; vitamin C recycling - 1A+2019
The Other Side of the Fascia: The SmoothMuscle Part 1
Bruno Bordoni, Marta Simonelli, Bruno MorabitoThis theoretical article challenges the standard definition of fascia. Traditionally, fascia is considered connective tissue originating from two embryonic layers, the mesoderm and ectoderm. The authors propose expandin…
fasciaMyofascialOsteopathicsmooth musclemesoderm - 1A+2019
The Other Side of the Fascia: Visceral Fascia, Part 2
Bruno Bordoni, Marta Simonelli, Bruno MorabitoThis editorial, part two of a series, argues for including certain internal organs (viscera) within the definition of fascia. From an osteopathic perspective, the authors suggest that understanding these organs as fasci…
fasciaMyofascialOsteopathicsmooth musclemesoderm - A+++2019
Future Aspects for Cannabinoids in Breast Cancer Therapy
Terézia Kisková, Felicitas Mungenast, Mária Suváková, Walter Jäger, Theresia ThalhammerThis scientific review explores how cannabinoids, such as THC and CBD, may influence breast cancer beyond their established role in palliative care for pain and nausea. Research suggests that cannabinoids might decelera…
CBD; Cannabis sativa; THC; breast cancer; cannabidiol; cannabinoid receptor; delta-9-tetrahydrocannabinol - A++2019
Development of a biotensegrity focused therapy for the treatment of pelvic organ prolapse: A retrospective case series
Anna Crowle, Clare HarleyThis retrospective case series explores a new biotensegrity-focused therapy for pelvic organ prolapse (POP). Challenging the common view that POP is caused by weak tissue, this approach hypothesizes that the condition i…
Myofascial releasebiotensegrityPelvic organ prolapsePelvic tension - A+2019
Collagen changes in pelvic support tissues in women with pelvic organ prolapse
Runqi Gong, Zhijun XiaThis narrative review summarizes research on how changes in collagen are linked to pelvic organ prolapse in women. Collagen is a critical component of the pelvic floor, providing essential supportive functions. Studies…
extracellular matrixcollagenBiomechanicsPelvic organ prolapseSignaling pathways - B2019
TMEM2: a missing link in hyaluronan catabolism identified?
Yu Yamaguchi, Hayato Yamamoto, Yuki Tobisawa, Fumitoshi IrieHyaluronan (HA) is a large molecule in our connective tissues that is broken down and replaced very quickly. Scientists have long understood that large HA molecules are first chopped into smaller pieces on the surface o…
hyaluronanhyaluronidaseTMEM2HA catabolism - A++2019
Effects of season long participation on ACL volume in female intercollegiate soccer athletes
Karen M Myrick, Andreas Voss, Richard S Feinn, Thomas Martin, Bernadette M Mele, Juan C GarbalosaThis study investigated how a competitive season affects the anterior cruciate ligament (ACL) in female collegiate soccer players. Researchers used MRI scans to measure ACL volume in 17 athletes before and after their s…
collagenAnterior cruciate ligamentintense physical trainingvolumetric changes in ligamentpre- to post season changes in ligament - 1A+2019
Bone Tissue is an Integral Part of the Fascial System
Bruno Bordoni, Maria Marcella LaganaThis review article proposes that bone tissue should be considered an integral part of the fascial system, a departure from the current definition. The authors support this by highlighting the shared embryological origi…
fasciaBonefascial systemMyofascial - A+2019
Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial
Patrick Jendricke, Christoph Centner, Denise Zdzieblik, Albert Gollhofer, Daniel KönigThis randomized controlled trial investigated the effects of combining resistance training with a daily intake of 15 grams of specific collagen peptides in premenopausal women. Over 12 weeks, participants trained three…
body composition; collagen peptides; hand-grip strength; leg press; premenopausal; protein supplementation; resistance training - A2019
The neural basis of the senses of effort, force and heaviness
Uwe Proske, Trevor AllenThis narrative review explores how we sense effort, force, and heaviness during muscle contraction. Traditionally, these sensations were thought to originate in the brain from copies of motor commands. However, new evid…
Force sense · Proprioception · Muscle spindle · Tendon organ · Motor command · Efference copy · Vibration - A++2019
Rehabilitation and nutrition protocols for optimising return to play from traditional ACL reconstruction in elite rugby union players: A case study
Gregory Shaw, Ben Serpell, Keith BaarThis case report followed two professional rugby players undergoing rehabilitation after an anterior cruciate ligament (ACL) reconstruction. In addition to a standard rehabilitation program, they received specific suppl…
collagenRehabilitationnutritionACL - A2019
Active Contractile Properties of Fascia
ROBERT SCHLEIP, WERNER KLINGLERThis narrative review explores how fascia, often seen as a passive tissue, can actively contract. Researchers point to the presence of cells called myofibroblasts within the fascia, which give it the ability to change i…
myofibroblast; fascia; connective tissue; contracture; stiffness; fibrosis - A2019
The diaphragm muscle manual evaluation scale
Bruno Bordoni, Bruno MorabitoThis technical report describes a new method for manually assessing the diaphragm's function, called the Manual Evaluation Diaphragm (MED) scale. The scale is designed to generate a value for the respiratory muscle's mo…
fasciaMyofascialdiaphragmSurgeryphrenic nerve - 1A+2019
Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation
Robert Schleip, G Gabbiani, Jan Wilke, I Naylor, B Hinz, A Zorn, Heike Jäger, R Breul, S Schreiner, Werner KlinglerThis study investigated whether fascia can actively contract, challenging the traditional view of it as a passive tissue. Researchers examined human and rat fascial samples for the presence of contractile cells called m…
Connective tissuestiffnessmyofibroblastscontractilitycontracture - A++2019
Acute Effects of Static Stretching on Muscle Strength and Power: An Attempt to Clarify Previous Caveats
Helmi Chaabene, David G Behm, Yassine Negra, Urs GranacherThis narrative review examines how static stretching affects subsequent strength and power. While static stretching was once thought to hinder performance, recent evidence suggests the duration of the stretch is the cri…
physiologyrange of motioninjurypassive stretchingphysical fitness - A2019
Role of Hyaluronan in Inflammatory Effects on Human Articular Chondrocytes
Mary K Cowman, Claire Shortt, Shivani Arora, Yuhong Fu, Jemma Villavieja, Jai Rathore, Xiayun Huang, Tatini Rakshit, Gy…Some researchers have proposed that fragments of hyaluronan (HA), a key molecule in connective tissue, can trigger inflammation in cartilage. This study investigated that idea in human articular cartilage cells. Researc…
hyaluronan; hyaluronidase; articular cartilage; chondrocytes; inflammation - A++2019
Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2
Liping Gan, Vladimir Camarena, Sushmita Mustafi, Gaofeng WangIn this study using cell cultures and animal models, researchers investigated how vitamin C might inhibit the spread of triple-negative breast cancer (TNBC). They found that vitamin C, at concentrations achievable throu…
F-actin; HIF-1α; YAP1; hippo pathway; lamellipodia; metastasis; synaptopodin 2; triple-negative breast cancer; vitamin C. - A2018
Measuring the Human Ultra-Weak Photon Emission Distribution Using an Electron-Multiplying, Charge-Coupled Device as a Sensor
Fernando Ortega-Ojeda, Matías Calcerrada, Alejandro Ferrero, Joaquín Campos, Carmen Garcia-RuizLiving systems, including humans, emit an extremely faint light called ultra-weak photon emission (UPE). This light is thought to be a byproduct of metabolic processes, particularly those involving reactive oxygen speci…
ultra-weak photon emission; spectrometer; measurement; electron multiplying charge coupled device sensor; liquid crystal tunable filter - 1A+++2018
Quantification of hyaluronan in human fasciae: variations with function and anatomical site
Caterina Fede, A Angelini, R Stern, V Macchi, A Porzionato, P Ruggieri, R De Caro, Carla SteccoThis study quantified for the first time the amount of hyaluronan (HA), a key lubricant, in human fascia from different parts of the body. Since HA is essential for the smooth gliding between fascial layers, understandi…
densification; extracellular matrix; fascia; fibrosis; gliding; hyaluronan; myofascial pain - A+++2018
Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability
Patrick Dressler, Dominic Gehring, Denise Zdzieblik, Steffen Oesser, Albert Gollhofer, Daniel KönigThis randomized, placebo-controlled study investigated the effect of specific collagen peptides on athletes with chronic ankle instability (CAI). Fifty athletes received either a daily collagen supplement or a placebo f…
collagennutritionAnkle sprainligaments - 1A+++2018
Emission of Biophotons and Adjustable Sounds by the Fascial System: Review and Reflections for Manual Therapy
Bruno Bordoni, F Marelli, B Morabito, B SacconiIn this narrative review, the authors explore how fascia, the web of connective tissue enveloping everything in the body, might communicate. They discuss research suggesting the fascial system may emit faint light parti…
fasciaMuscleManual TherapyMyofascialOsteopathic - A2018
Metabolic acidosis and the role of unmeasured anions in critical illness and injury
Tobias Zingg, Bishwajit Bhattacharya, Linda L MaerzIn this review article, the authors discuss metabolic acidosis, a common condition in critically ill patients that is associated with increased mortality. A significant component of this acidosis can be caused by so-cal…
Metabolic acidosisUnmeasured anionsStrong ion differenceStrong ion gapAnion gap Base excess - A++2018
Bone is fascia
Stephen LevinThis entry, based on its title alone, proposes a conceptual link between bone and fascia. Without an abstract or full text, the specific arguments made by the author remain unclear. The title 'Bone is fascia' suggests a…
fascia - B2018
Cellular Mechanotransduction: From Tension to Function
F Martino, A R Perestrelo, V Vinarský, S Pagliari, G ForteIn this review article, the authors describe mechanotransduction—the process by which cells sense and respond to physical forces from their environment, such as the extracellular matrix. These mechanical cues are conver…
mechanotransductionnucleoskeletonfocal adhesionmechanobiologymechanosensor - A2018
Lipedema—An update
Uwe WollinaThis review provides an update on lipedema, a chronic condition affecting subcutaneous fat tissue in the limbs, almost exclusively in women. It typically appears during or after puberty and is characterized by symmetric…
painEdemaobesitylipedemalymphedema - A+2018
Negative Air Ions and Their Effects on Human Health and Air Quality Improvement
Shu-Ye Jiang, Ali Ma, Srinivasan RamachandranThis review paper examines the research on negative air ions (NAIs) and their effects on human health and air quality. Used for over a century in air cleaning, NAIs are associated with improved psychological health and…
negative air ions; superoxide; particulate matter; pulsed electric field - A+2018
Lymphatic System Flows
James E Moore Jr, Christopher D BertramThe lymphatic system plays a crucial role in the body's fluid balance by collecting fluid that has leaked from blood vessels and returning it to the bloodstream. This process works against an adverse pressure gradient,…
Physiology; Oedema; Cancer; Immunology; Lymph - A2018
Immediate effects of self-myofascial release on latent trigger point sensitivity: a randomized, placebo-controlled trial
Jan Wilke, Lutz Vogt, Winfried BanzerThis randomized, placebo-controlled trial examined whether foam rolling could immediately reduce sensitivity in latent trigger points. Researchers compared 90 seconds of static compression, dynamic rolling, and a placeb…
fasciaMyofascial painFoam rollingSelf-masage - A2018
Comparison of vibration rolling, nonvibration rolling, and static stretching as a warm-up exercise on flexibility, joint proprioception, muscle strength, and balance in young adults
Chia-Lun Lee, I-Hua Chu, Bo-Jhang Lyu, Wen-Dien Chang, Nai-Jen ChangThis study compared the immediate effects of three warm-up techniques in young adults: vibration rolling, non-vibration rolling, and static stretching. Researchers measured changes in lower-body flexibility, joint posit…
Vibration; self-myofascial release; foam rolling; exercise; performance - A+++2018
Effect of Health-Promoting Agents on Exclusion-Zone Size
Abha Sharma, Colby Adams, Benjamin D Cashdollar, Zheng Li, Nam V Nguyen, Himasri Sai, Jiachun Shi, Gautham Velchuru, Ke…This experimental study investigated how various health-promoting agents affect the formation of "exclusion zone" (EZ) water, often referred to as the fourth phase of water. Researchers found that substances such as hol…
dose dependent; dose response; exclusion zone water; health-promoting agents; hydrophilic surface; nutraceuticals - B2018
Effectiveness of sodium bicarbonate infusion on mortality in septic patients with metabolic acidosis
Zhongheng Zhang, Carlie Zhu, Lei Mo, Yucai HongThis retrospective database study investigated whether sodium bicarbonate infusion affected mortality in septic patients with metabolic acidosis. The researchers found no overall survival benefit in the general populati…
sepsiscritical careSodium bicarbonateMortalityMarginal structural Cox - A2018
A fundamental critique of the fascial distortion model and its application in clinical practice
Christoph ThalhamerThis narrative review critiques the Fascial Distortion Model (FDM), a manual therapy approach based on the idea that all musculoskeletal complaints stem from distortions of fascia. The author investigated the scientific…
Manual Therapyfasciaefascial distortion modelreductionismtypaldos - 1A+2018
The Fasciacytes- A New Cell Devoted To Fascial Gliding Regulation
Carla Stecco, Caterina Fede, Veronica Macchi, Andrea Porzionato, Lucia Petrelli, Carlo Biz, Robert Stern, Raffaele De C…Researchers have identified a new type of cell within fascia, which they have named "fasciacytes." This study presents evidence that these specialized cells are responsible for producing hyaluronan, a key component of t…
hyaluronanfasciafasciacytesextracellular matrix - A2018
Not merely a protective packing organ? A review of fascia and its force transmission capacity
Jan Wilke, Robert Schleip, Can A Yucesoy, Winfried BanzerThis review article examines fascia's role in transmitting force throughout the body. Traditionally seen as just a "packing" material, research now suggests fascia is an active tissue that connects muscles into a body-w…
epimuscular; fascia; force transmission; myofascial chains - A+2018
Endogenous systems involved in exercise-induced analgesia
R DA SILVA SANTOS, G GALDINOThis narrative review describes the phenomenon of exercise-induced analgesia, which is the pain-relieving effect of physical activity. Studied since the 1970s, this effect is seen in both endurance and resistance exerci…
EndocannabinoidspainexerciseNitric oxideanalgesia - A++2018
Low-frequency vibrotherapy considerably improves the effectiveness of manual lymphatic drainage (MLD) in patients with lipedema: A two-armed, randomized, controlled pragmatic trial
Rainer SchneiderThis randomized controlled trial investigated the effect of adding low-frequency vibrotherapy to manual lymphatic drainage (MLD) for 30 women with stage 2–3 lipedema. Participants were randomly assigned to receive eithe…
Lipedema; MLD; quality of life; shock wave vibrotherapy - A++2018
Emerging Therapies for Spastic Movement Disorders
Preeti RaghavanSpasticity following a central nervous system injury can cause muscle stiffness, partly due to secondary changes in muscles and connective tissue. The 'hyaluronan hypothesis' suggests that an accumulation of hyaluronan,…
Spasticity; Muscle stiffness; Peripheral mechanism; Stroke; Brain Injury; Hyaluronidase; Hyaluronic Acid; Hyaluronan hypothesis - A++2018
Subcutaneous adipose tissue therapy reduces fat by dual X-ray absorptiometry scan and improves tissue structure by ultrasound in women with lipoedema and Dercum disease
M Ibarra, A Eekema, C Ussery, D Neuhardt, K Garby, K L HerbstThis small study investigated a non-surgical therapy for subcutaneous adipose tissue in seven women with lipoedema or Dercum disease. Over four weeks of treatment, participants experienced significant reductions in weig…
lipoedemaDercum diseasesubcutaneous adipose tissue. - A2018
Lipedema
Caitriona Canning, John R BartholomewA detailed summary of this 2018 publication by Caitriona Canning and John R. Bartholomew is not yet available. The work is titled simply 'Lipedema,' suggesting it may be a general overview or review of the condition. Wi…
lipedemalipoedemalipolymphedemavascular medicine - A2018
Frontiers in fascia research
Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…
fasciaultrasound.Pain therapySport sciencesIndentometry - B2018
The different distribution of enzymatic collagen cross-links found in adult and children bone result in different mechanical behavior of collagen
B Depalle, A G Duarte, I A K Fiedler, L Pujo-Menjouet, M J Buehler, J-P BerteauThis computational study explored how molecular bonds called collagen cross-links affect bone mechanics differently in children and adults. Using models based on real bone samples, researchers simulated how collagen fib…
Cross-linksChildren boneMolecular modelingBiomechanical properties - A2018
The infrapatellar fat pad and the synovial membrane: an anatomo-functional unit
Veronica Macchi, Elena Stocco, Carla Stecco, Elisa Belluzzi, Marta Favero, Andrea Porzionato, Raffaele De CaroThis descriptive review summarizes evidence on the close relationship between the infrapatellar fat pad and the synovial membrane in the knee. Anatomically, they are linked, as parts of the synovial membrane insert into…
infrapatellar fat pad; knee plicae; osteoarthritis; synovial membrane. - A2018
What Is the Point? The Problem with Acupuncture Research That No One Wants to Talk About
Helene M Langevin, Peter M WayneIn this 2018 commentary, the authors address a persistent criticism of acupuncture research: the unclear scientific basis for "acupuncture points." They argue that the acupuncture research community has not paid enough…
acupunctureAnatomyacupuncture pointsmethodology - A+++2018
Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement
Martina Zügel, Constantinos N Maganaris, Jan Wilke, Karin Jurkat-Rott, Werner Klingler, Scott C Wearing, Thomas Findley…This consensus statement reviews the current state of knowledge on fascial tissue in sports medicine. It describes fascia as a body-wide network of connective tissue that integrates all body systems and is crucial for m…
fasciainjurysports medicine - A+++2018
Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study
Do-Un Kim, Hee-Chul Chung, Jia Choi, Yasuo Sakai, Boo-Yong LeeThis randomized, double-blind, placebo-controlled study evaluated the effects of daily low-molecular-weight collagen peptide (LMWCP) supplementation on the skin of 64 women. Over 12 weeks, researchers measured skin hydr…
collagen hydrolysate; collagen tripeptide; fish collagen; low-molecular-weight collagen peptide; photoaging; skin elasticity; skin hydration; skin wrinkling; type I collagen. - A2018
Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas
Mari Valkonen, Hannu Haapasalo, Kirsi Rilla, Kristiina Tyynelä-Korhonen, Ylermi Soini , Sanna Pasonen-SeppänenAstrocytomas are the most common type of brain tumor in adults. In this retrospective study, researchers investigated hyaluronan, a key component of the brain's extracellular matrix, and its related enzymes in 163 tumor…
hyaluronanHyaluronan synthaseAstrocytomaPrognosisGlioma