Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
- A++2020
Ultrasound imaging of a scar on the knee: Sonopalpation for fascia and subcutaneous tissues
Carmelo Pirri, Antonio Stecco, Caterina Fede, Raffaele De Caro, Carla Stecco, Levent ÖzçakarPersistent pain from surgical or trauma-related scars is a common and sometimes debilitating problem. In this article, the authors describe the use of ultrasound imaging to provide an objective diagnosis for debilitatin…
fasciapainscarultrasonographyknee - A+++2020
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X WongThis randomized controlled trial investigated how daily resveratrol supplementation affects brain health in postmenopausal women over a 12-month period. Participants took either 75 mg of trans-resveratrol twice daily or…
ageing; cerebrovascular function; cognitive decline; menopause; neurovascular coupling; nutraceutical; phytoestrogen; resveratrol - A2020
Ageing of the diaphragm muscle
Bruno Bordoni, Bruno Morabito, Marta SimonelliThis narrative review explores how the diaphragm, our main breathing muscle, is affected by aging. Like other muscles, the diaphragm can weaken and lose mass over time, a condition known as sarcopenia. This age-related…
fasciadiaphragmskeletal musclephrenic nervevagus nerve - A2020
Whole body vibration in the static modified push-up position in untrained healthy women stimulates neuromuscular system potentiating increased handgrip myogenic response
Ana Lúcia Cristino de Souza, Vanessa Amaral Mendonca, Ana Carolina Coelho de Oliveira, Sueli Ferreira da Fonseca, Lucia…This study investigated the acute effects of vibration on handgrip strength in untrained women. Participants placed their hands on a vibrating platform in a modified push-up position for five minutes. Researchers found…
Electromyography; Exposure to vibration; Grip strength; Muscular performance. - A++2020
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
Lijun Wang, Xiuling You, Sutada Lotinun, Lingli Zhang, Nan Wu, Weiguo ZouThis study using mouse models investigates how the protein PIEZO1 acts as a mechanical sensor in the skeleton to regulate bone mass. Researchers found that a deficiency of PIEZO1 in bone-forming cells (osteoblasts) lead…
mechanotransductionpiezobone homeostasis - A+++2020
Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts
Torsten Lowin, Ren Tingting, Julia Zurmahr, Tim Classen, Matthias Schneider, Georg PongratzThis laboratory study investigated how cannabidiol (CBD) affects synovial fibroblasts, the cells responsible for joint destruction in rheumatoid arthritis. Researchers found that CBD can reduce the viability of these ce…
inflammationfibroblastCannabinoidsrheumatoid arthritissynovia - A++2020
Integrating mental imagery and fascial tissue: A conceptualization for research into movement and cognition
Amit Abraham, Eric Franklin, Carla Stecco, Robert SchleipThis narrative review explores the connection between mental imagery and fascial tissue, a field that has historically focused on muscles and the nervous system. The authors propose that specific mental visualizations d…
Body schema; Cognition; Dynamic neuro-cognitive imagery; Fascia; Mental imagery; Movement - A++2020
What is the Intelligent Tissue !eory and How Does it Relate to Acupuncture?
Fletcher KovichThis article introduces the "intelligent tissue theory," which proposes that organ information is transmitted via electromagnetic waves and interpreted by bodily tissues at specific meridians. The author suggests that t…
acupunctureChiintelligent tissueNei Jing - A+++2020
The Cranial Bowl in the New Millennium and Sutherland's Legacy for Osteopathic Medicine: Part 2
Bruno Bordoni, Stevan Walkowski, Bruno Ducoux, Filippo TobbiThis narrative review, the second in a series, discusses how modern scientific research challenges some of the original concepts of cranial osteopathy. The authors examine the mechanical characteristics of cranial struc…
fasciaManual TherapyOsteopathiccraniocraniosacral - A2020
Muscle Cramps
Bruno Bordoni, Kavin Sugumar, Matthew VaracalloMuscle cramps are involuntary, painful, and localized contractions of a muscle or muscle fibers, often felt as a palpable knot. While common in sports, their exact cause is not fully understood and likely depends on var…
Diagnosiscramp - A+++2020
A Potential Involvement of Anandamide in the Modulation of HO/NOS Systems: Women, Menopause, and "Medical Cannabinoids"
Renáta Szabó, Denise Börzsei, Zsuzsanna Szabó, Alexandra Hoffmann, István Zupkó, Dániel Priksz, Krisztina Kupai, Csaba…This animal study using an estrogen-deficient rat model investigated how the endocannabinoid anandamide (AEA) affects cardiovascular health during menopause-like conditions. Researchers found that estrogen loss reduced…
anandamide; cardiovascular system; heme oxygenase; nitric oxide synthase - A++++2020
Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths
William B Grant, Henry Lahore, Sharon L McDonnell, Carole A Baggerly, Christine B French, Jennifer L Aliano, Harjit P B…In this 2020 review article, the authors examine evidence that vitamin D could reduce the risk of respiratory tract infections, including influenza and COVID-19. They propose that vitamin D works through several mechani…
acute respiratory distress syndrome (ARDS); ascorbic acid; cathelicidin; coronavirus; COVID-19; cytokine storm; influenza; observational; pneumonia; prevention; respiratory tract infection; solar radiation; treatment; UVB; vitamin C; vitamin D - A2020
Low-intensity vibration restores nuclear YAP levels and acute YAP nuclear shuttling in mesenchymal stem cells subjected to simulated microgravity
Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes UzerAstronauts lose bone and muscle in space, partly because their cells become less responsive to mechanical forces. This study investigated if low-intensity vibration (LIV) could help counteract this effect in a lab setti…
vibrationsstem cellsmicrogravity - A+++2020
Fasting-mimicking diet plus chemotherapy in breast cancer treatment
Claudio Vernieri, Francesca Ligorio, Emma Zattarin, Licia Rivoltini, Filippo de BraudThis clinical trial investigated whether a fasting-mimicking diet (FMD) combined with chemotherapy could improve outcomes for breast cancer patients. The overall results were negative, meaning the study did not find a s…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; breast cancer - A2020
Evaluation of scapular mobilization and comparison to pectoralis minor stretching in individuals with rounded shoulder posture: A randomized controlled trial
Maedeh Fani, Samaneh Ebrahimi, Ali GhanbariThis randomized controlled trial investigated treatments for rounded shoulder posture in 52 healthy students. Researchers compared the effects of scapular mobilization, pectoralis minor self-stretching, and a combinatio…
Mobilization; Pectoralis minor stretching; Rounded shoulder; Scapular kinematics. - A2020
Lymphatic treatments after orthopedic surgery or injury: A systematic review
Ifat Klein, Dorit Tidhar, Leonid KalichmanThis systematic review examined the effectiveness of lymphatic and compression therapies for reducing swelling and pain after orthopedic surgery or injury. Researchers analyzed 15 studies, finding that for persistent sw…
Compression therapy; Edema; Lymphatic therapy; Orthopedic surgery; Postoperative treatment. - A++2020
Simulation and Modeling of Telocytes Behavior in Signaling and Intercellular Communication Processes
Dragos Cretoiu, Simona Roatesi, Ion Bica, Cezar Plesca, Amado Stefan, Oana Bajenaru, Carmen Elena Condrat, Sanda Maria…Telocytes are a unique type of interstitial cell with long extensions that form networks, thought to be involved in local tissue equilibrium and regeneration. In this study, researchers used computer simulation and math…
content-based image retrieval; image indexation; modeling of living cell behavior; telocyte network tracking and indexing; telocytes; viscoelastic constitutive laws - A++2020
Applicability of Low-intensity Vibrations as a Regulatory Factor on Stem and Progenitor Cell Populations
Oznur Baskan, Ozge Karadas, Gulistan Mese, Engin OzciviciThis narrative review explores how mechanical forces, specifically low-intensity vibrations, can influence stem cells. While high-impact activities like running are known to build tissue, they are not suitable for every…
Stem cell; biomechanics; mechanobiology; progenitor cell populations; tissue engineering; vibrations - A2020
Role of fascial connectivity in musculoskeletal dysfunctions: A narrative review
M S Ajimsha, Pramod D Shenoy, Neeraj GampawarThis narrative review examines the concept of "fascial connectivity," which suggests that muscles and fascia are linked in functional chains throughout the body. The authors analyzed 35 studies, including cadaveric, ani…
Fascia; Fascial connectivity; Myofascial chains; Myofascial meridians. - A+++2020
Propolis-induced exclusion of colloids: Possible new mechanism of biological action
Magdalena Kowacz, Gerald H PollackThis laboratory study investigates how propolis (bee glue) interacts with water to create an exclusion zone (EZ)—a layer of water that repels solutes and microorganisms. The researchers found that surfaces coated with p…
Colloid-surface repulsion; Exclusion zone; Propolis - A2020
PIEZO2: A Novel Molecule Involved in the Development of AIS
Zhichong Wu, Yuwen Wang, Chao Xia, Zhenhua Feng, Yong Qiu, Jack Chun-Yiu Cheng, Leilei Xu, Zezhang ZhuThis case-control study investigated the potential link between the PIEZO2 gene, proprioception (the body's sense of position), and adolescent idiopathic scoliosis (AIS). Researchers found that AIS patients often exhibi…
proprioceptionpiezo2AIS - B2020
Sympathetic activation: a potential link between comorbidities and COVID-19
Andrea Porzionato, Aron Emmi, Silvia Barbon, Rafael Boscolo-Berto, Carla Stecco, Elena Stocco, Veronica Macchi, Raffael…In this perspective article, researchers propose a potential link between common comorbidities and severe COVID-19 outcomes. Conditions like heart disease, hypertension, and diabetes, which are risk factors for severe C…
autonomic nervous system; COVID-19; diabetes; heart failure; hypertension; kidney disease; obesity; SARS-CoV-2; smoking; sympathoactivation - A2020
Pilates exercise improves the clinical and immunological pro!les of patients with human T-cell lymphotropic virus 1 associated myelopathy: A pilot study
Altair Vallinoto Klautau, Denise da Silva Pinto, Bárbara Brasil Santana, Maria Alice Freitas Queiroz, Andréa Nazar!e M…This pilot study investigated the effects of a 10-week Pilates program for eight patients with the chronic inflammatory disease HAM/TSP. After the exercise period, participants experienced significant improvements in pa…
cytokinesHTLV-1HTLV-1-Associated myelopathyPilates - A+++2020
The role of cannabinoids in the treatment of cancer
L Vecera, T Gabrhelik, P Prasil, P StouracThis review article summarizes current knowledge on how cannabinoids and their receptors modulate tumor diseases. Research suggests that cannabinoids may influence cancer progression by stimulating programmed cell death…
cancer; cannabinoid receptor; cannabinoids; oncological diseases cancer treatment - A2020
Anatomy, Head and Neck, Anterior Vagus Nerve
Maximo Baquiran, Bruno BordoniThis article is an anatomical description of the anterior vagus nerve in the head and neck. As only the title is available, the content has not yet been summarized in detail. The title suggests the text provides an over…
Anatomyvagus nervecranial nerve - A+++2020
Effects of vitamin C on oxidative stress, inflammation, muscle soreness, and strength following acute exercise: meta-analyses of randomized clinical trials
Natiele Camponogara Righi, Felipe Barreto Schuch, Angélica Trevisan De Nardi, Caroline Montagner Pippi, Geovana de Alme…This meta-analysis compiled results from 18 randomized clinical trials to investigate the effects of vitamin C supplementation following a single bout of exercise. The researchers found that vitamin C reduced certain ma…
inflammationOxidative stressexerciseathleteAscorbic acid - A+++2020
Establishment of a Novel Porcine Model to Study the Impact of Active Stretching on a Local Carrageenan-Induced Inflammation
Dennis Muñoz Vergara, Lisbeth Berrueta, Colleen Carmody, Xingxing An, Peter M Wayne, Ann Marie Zavacki, Helene M Langev…This animal study used a novel porcine model to investigate how active stretching affects controlled inflammation in the connective tissue of the back. Researchers trained pigs to perform a specific stretch twice daily…
Stretch - A+++2020
Mechanical stimulation of human dermal fibroblasts regulates pro-inflammatory cytokines: potential insight into soft tissue manual therapies
Aric Anloague, Aaron Mahoney, Oladipupo Ogunbekun, Taylor A Hiland, William R Thompson, Bryan Larsen, M Terry Loghmani,…This lab study investigated how mechanical forces, similar to those in manual therapy, affect human skin cells. Researchers first applied a repetitive strain to cultured dermal fibroblasts to simulate an overuse injury,…
inflammationMyofascial releaseManual Therapyphysical therapyphysiotherapy - A2020
Quantitative analysis of gliding between subcutaneous tissue and the vastus lateralis - Influence of the dense connective tissue of the myofascia
Kengo Kawanishi, Shintarou KudoThis study investigated the relationship between the thickness of connective tissue layers and their ability to glide past one another. Using ultrasound, researchers observed the vastus lateralis muscle on the outer thi…
Connective tissue; GLIDING; Particle image velocimetry. - A+2020
Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X WongThis 24-month randomized, double-blind, placebo-controlled crossover study investigated the effects of daily resveratrol supplementation in 125 postmenopausal women. The researchers found that regular intake of 75 mg re…
Resveratrolsupplementation - A++2020
The potential role of cannabinoids in dermatology
Tabrez Sheriff, Matthew J Lin, Danielle Dubin, Hooman KhorasaniThis literature review explores how cannabinoids, including both plant-derived and endogenous versions, may affect the skin through the endocannabinoid system. Research suggests that the skin possesses its own receptors…
Cannabinoids in dermatology; cannabidiol; cannabis; endocannabinoids. - A2020
A Hyaluronan-binding Peptide (P15-1) Reduces inflammatory and catabolic events in IL-1beta-treated human articular chondrocytes
Claire Shortt, Leonard G Luyt, Eva A Turley, Mary K Cowman, Thorsten KirschInflammation in osteoarthritis drives cartilage degradation. In this laboratory study, researchers investigated whether a peptide (P15-1) combined with hyaluronan (HA) could protect human cartilage cells in a simulated…
hyaluronaninflammationchondrocytesP15-1IL-1beta - A2020
The link between vitamin D and COVID-19: distinguishing facts from fiction
P BergmanThis 2020 article, available only by title, appears to be a review or commentary on the relationship between vitamin D and COVID-19. The title, "The link between vitamin D and COVID-19: distinguishing facts from fiction…
COVID-19vitamin D - A++2020
Mesothelial Cells Covering the Surface of Primo Vascular System Tissue
Chae Jeong Lim, Yeo Sung Yoon, Pan Dong RyuIn this study on rats, researchers investigated the cells on the outer surface of the primo vascular system (PVS), a proposed circulatory network. Using various microscopy and staining techniques, they identified these…
HBME-1; hematoxylin and eosin staining (H&E); periductium; primo node; primo vessel; scanning electron microscopy (SEM) - A2020
Virtual reality in the rehabilitation process for individuals with cerebral palsy and Down syndrome: A systematic review
Jamile Benite Palma Lopes, Natalia de Almeida Carvalho Duarte, Roberta Delasta Lazzari, Claudia Santos OliveiraThis systematic review compiled research on virtual reality (VR) as a rehabilitation tool for children with cerebral palsy and Down syndrome. Researchers analyzed five high-quality studies and found that VR training, bo…
Cerebral palsy; Down syndrome; Movement analysis; Virtual reality. - A+++2020
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
Eduardo Dourado, Margarida Ferro, Catarina Sousa Guerreiro, João Eurico FonsecaThis narrative review explores how dietary patterns can influence the gut microbiota in individuals with rheumatoid arthritis (RA). Research indicates that RA patients often exhibit significant differences in their inte…
Mediterranean diet; gut microbiota; probiotics; rheumatoid arthritis - C2020
Endothelial mechanobiology
Ming He, Marcy Martin, Traci Marin, Zhen Chen, Brendan GongolThis narrative review explores how the cells lining our blood vessels, called endothelial cells, respond to the mechanical forces of blood flow. It describes two main patterns: smooth, pulsatile flow in straight vessels…
mechanotransductionmechanpbiologyendothelial cellsvasculatory disease - A2020
Effects of vibration therapy on neuromuscular efficiency & features of the EMG signal based on endurance test
Mohd Mukhtar Alam, Abid Ali Khan, Mohd FarooqThis study investigated how vibration therapy at different frequencies (23 Hz and 35 Hz) affects forearm muscle performance and fatigue. Researchers used electromyography (EMG) to measure electrical activity in four for…
EMG features; Fatigue assessment; Maximal voluntary contraction; Neuromuscular performance; Surface electromyography; Vibration therapy. - A++2020
Embryology of the Fascial System
Leonardo VieiraThis review article explores how the fascial system develops in the human embryo, highlighting its role as a continuous network that integrates all body systems. The author describes how different types of fascia—includ…
embryology; fascia; fascial system; human development; neuro-fasciagenic - A2020
Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province
Kui Liu, Yuan-Yuan Fang, Yan Deng, Wei Liu, Mei-Fang Wang, Jing-Ping Ma, Wei Xiao, Ying-Nan Wang, Min-Hua Zhong, Cheng-…This retrospective study analyzed clinical data from 137 patients with the novel coronavirus (2019-nCoV) hospitalized in China's Hubei province during the initial outbreak. The most common initial symptoms were fever, c…
Coronavirus; 2019 Novel coronavirus (2019-nCoV); Clinical characteristics; Treatment; Hubei province - A+++2020
Endocannabinoids release after Osteopathic Manipulative Treatment. A brief review
Andrea Buscemi, Simona Martino, Santi Scirè Campisi, Alessandro Rapisarda, Marinella CocoThis brief review examines how Osteopathic Manipulative Treatment (OMT) may influence the body's endocannabinoid system, which is crucial for pain regulation and emotional well-being. By analyzing existing research, the…
chronic pain; endocannabinoids; hypothalamic-pituitary-adrenal axis; osteopathic manipulative treatment - A+2020
Tissue Micro-channels Formed by Collagen Fibers and their Internal Components: Cellular Evidence of Proposed Meridian Conduits in Vertebrate Skin
Bai Xuebing, Wu Ruizhi, Zhang Yue, Liang Chunhua, Shi Yonghong, Zhang Yingxin, Ding Baitao, Imran Tarique, Yang Ping, C…This study examined fascia from various vertebrate species using microscopy to search for physical structures that might correspond to the meridian conduits described in Traditional Chinese Medicine (TCM). Researchers i…
Collagen fiberTelocyteChinese traditional medicinemeridian conduittissue micro-channel - A+++2020
Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women
Cemal Ozemek, Kerry L Hildreth, Patrick J Blatchford, K Joseph Hurt, Rachael Bok, Douglas R Seals, Wendy M Kohrt, Kerri…This randomized pilot study investigated how a single dose of resveratrol or estradiol affects endothelial function in postmenopausal women. The findings suggest that while both substances can improve the blood vessels'…
aerobic exercise; endothelial function; nutraceutical; sex hormones; women - A+++2020
Movement Caused by Electrical Stimulation of the Lumbosacral Region in Standing Horses
Daniela C Riedler, Rebeka R Zsoldos, Matthias Robel, Isabelle D Jobst, Theresia F LickaThis study investigated how electrical stimulation (ES) affects movement in the lower back and pelvis of standing horses compared to manual techniques. While both methods successfully triggered movement in the lumbosacr…
Electrical stimulation; Lumbosacral; Pelvic inclination; Physical therapy; Sacroiliac - A++2020
Therapeutic importance of hydrogen sulfide in age-associated neurodegenerative diseases
Rubaiya Tabassum, Na Young Jeong, Junyang JungThis narrative review explores the potential of molecular hydrogen (H2) as a preventive and therapeutic medical gas for various health conditions. H2 acts as a selective antioxidant, specifically targeting the most harm…
3-mercaptopyruvate sulfurtransferase; aging; antioxidant; cystathionine β-synthase; cystathionine γ-lyase; glutathione; hydrogen sulfide; neurodegenerative disease; oxidative stress; reactive oxygen species - A+++2020
The immediate effect of IASTM vs. Vibration vs. Light Hand Massage on knee angle repositioning accuracy and hamstrings flexibility: A pilot study
George A Koumantakis, Eleonora Roussou, Georgios A Angoules, Nikolaos A Angoules, Theodoros Alexandropoulos, Georgia Ma…This pilot study compared the immediate effects of three different soft tissue techniques on the hamstrings of 16 healthy men. The techniques were instrument-assisted soft tissue mobilization (IASTM), vibration massage,…
fasciaproprioceptionMassageMuscle tightness - A+++2020
Gut Microbiota and Cardiovascular Disease
Marco Witkowski, Taylor L Weeks, Stanley L HazenThis review explores how the gut microbiota influences cardiovascular health through the production of specific metabolic byproducts. Research suggests that the link is not merely associative; certain bacterial metaboli…
atherosclerosis; cardiovascular diseases; gastrointestinal microbiome; thrombosis; vascular diseases - A+++2020
Perspective: Vitamin D deficiency and COVID-19 severity –plausibly linked by latitude, ethnicity, impacts on cytokines,ACE2 and thrombosis
J M Rhodes, S Subramanian, E Laird, G Griffin, R A KennyThis narrative review explores the potential link between vitamin D deficiency and the severity of COVID-19. The authors observed that countries at higher latitudes, with less sun exposure, had higher COVID-19 mortality…
cytokineCOVID-19vitamin D - A++2020
The Efficacy of Stretching Exercises on Arterial Stiffness in Middle-Aged and Older Adults: A Meta-Analysis of Randomized and Non-Randomized Controlled Trials
Michitaka Kato, Fumi Nihei Green, Kazuki Hotta, Toshiya Tsukamoto, Yasunari Kurita, Akira Kubo, Hisato TakagiThis meta-analysis reviewed eight studies involving 213 middle-aged and older adults to see how stretching affects arterial stiffness. The combined results suggest that regular stretching can significantly reduce arteri…
stretching exercises; arterial stiffness; endothelial function; middle-aged; older adult - B2020
Neuromuscular activation analysis of the trunk muscles during hippotherapy sessions
Júlio Ribeiro Bravo Gonçalves Junior, André Gustavo Fernandes de Oliveira, Silvia Almeida Cardoso, Kamila Gabriela Jaco…This study investigated how hippotherapy (therapeutic horseback riding) affects trunk muscle activation in children. Researchers measured the activity of four key back and shoulder muscles during a 30-minute session, co…
HippotherapyElectromyographyMuscle activation - A+++2020
The feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back on the structural and functional properties of the lumbar area in female soccer players: a randomised, placebo-controlled pilot study design
Patrick Weber, Christine Graf, Werner Klingler, Nadine Weber, Robert SchleipThis is a protocol for a pilot study designed to investigate the feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back in female soccer players. The researchers plan to compare IAMT with…
Thoracolumbar fasciaMyofascialultrasound.AthletesInstrument-assisted - A++2020
The Structure and Role of Intramuscular Connective Tissue in Muscle Function
Peter P PurslowThis narrative review analyzes the microscopic structure of intramuscular connective tissue—endomysium, perimysium, and epimysium—and its role in muscle function. Rather than acting simply as a container, this connectiv…
extracellular matrixMusclecollagenmechanotransductionperimysium - A+++2020
Ascorbate as Prophylaxis and Therapy for COVID-19—Update From Shanghai and U.S. Medical Institutions
Richard Z Cheng, Mikhail Kogan, Devra DavisThis 2020 report describes how a medical panel in Shanghai evaluated the use of intravenous (IV) ascorbate, or vitamin C, for patients with severe COVID-19. The panel reviewed existing studies and preliminary data from…
COVID-19public healthglobal healthintravenous ascorbate - A2020
A Novel Role of Ascorbic Acid in Anti-Inflammatory Pathway and ROS Generation in HEMA Treated Dental Pulp Stem Cells
Francesca Diomede, Guya Diletta Marconi, Simone Guarnieri, Michele D’Attilio, Marcos F X B Cavalcanti, Maria A Mariggiò…Components from common dental resins can sometimes cause inflammation and oxidative stress in the cells of the dental pulp. This laboratory study investigated whether ascorbic acid (Vitamin C) could protect human dental…
human dental pulp stem cells; hema; ascorbic acid; nfkb; erk; perk; inflammatory cytokines - A+++2020
Is the VITAMINS RCT indicating potential redundancy between corticosteroids and vitamin C?
Anitra C CarrKnown only by its title, this article appears to be a commentary or analysis of a randomized controlled trial (RCT) known as VITAMINS. The title poses a question about whether there might be a "redundancy," or overlappi…
Vitamin Ccorticosteroidsstress respons - A+++2020
Overview of the possible role of vitamin C in management of COVID-19
Anis Abobaker, Aboubaker Alzwi, Alsalheen Hamed A AlraiedIn this 2020 review, the authors examine the possible role of vitamin C in managing COVID-19. They note that the body's vitamin C levels often drop during an acute infection due to increased metabolic demands. Because v…
Vitamin CCOVID-19SARS-CoV-2Beneficial effectsManagement - A2020
Anatomy, Tendons
Bruno Bordoni, Matthew VaracalloThis is a placeholder for a summary of a publication titled "Anatomy, Tendons". The full text has not yet been reviewed by our team. Once summarized, this entry will provide an overview of the key anatomical features of…
fasciatendonsAnatomytendon sheaths - A+++2020
An anatomical comparison of the fasciae of the thigh: A macroscopic, microscopic and ultrasound imaging study
Carmelo Pirri, Caterina Fede, Lucia Petrelli, Diego Guidolin, Chenglei Fan, Raffaele De Caro, Carla SteccoResearchers compared the thigh's fascial layers using three methods: dissection of cadavers, microscopic analysis, and ultrasound imaging of living volunteers. They identified distinct layers, including a superficial fa…
fascia lataImagingThicknessmusculo-skeletal ultrasoundsuperficial fascia - A+2020
Ankle Motion Is Associated With Soft Tissue Displacement in the Dorsal Thigh: An in vivo Investigation Suggesting Myofascial Force Transmission Across the Knee Joint
Jan Wilke, Heloise Debelle, Sarah Tenberg, Andrew Dilley, Constantinos MaganarisThis study investigated how ankle motion affects tissue in the back of the thigh. Researchers passively stretched the calves of healthy participants lying prone with an extended knee. Using ultrasound, they observed tha…
fasciamyofascial chainsultrasound.Myofascial force transmissionrange of motion - A+++2020
Effects of Cesarean Section and Vaginal Delivery on Abdominal Muscles and Fasciae
Chenglei Fan, Diego Guidolin, Serena Ragazzo, Caterina Fede, Carmelo Pirri, Nathaly Gaudreault, Andrea Porzionato, Vero…This study used ultrasound to compare the abdominal muscles and fascia of women who had a C-section, a vaginal delivery, or had never given birth. Researchers found that both types of delivery were associated with chang…
caesarean section; vaginal delivery; fascia; abdominal muscles; pain; ultrasound