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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
Showing 241–300 of 427 studies · page 5/8A
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  1. A
    2014

    Skin, fascias, and scars: symptoms and systemic connections

    Bruno Bordoni, Emiliano Zanier

    This review article explores how skin, fascia, and scars are interconnected and can affect the entire body. The authors describe the skin as an organ that communicates with the nervous system and other structures. When…

    fasciaOsteopathicSkinscarringscar
  2. A
    2014

    Chiropractic Management of Pubic Symphysis Shear Dysfunction in a Patient With Overactive Bladder

    Robert Cooperstein, Anthony Lisi, Andrew Burd

    This case report describes the chiropractic care of a 24-year-old woman with an overactive bladder, specifically frequent nighttime urination that disrupted her sleep. A physical examination revealed a shear dysfunction…

    fasciasymphysis pubis dysfunctionpubic symphysispubic symphysis diastasisurinary bladder overactive
  3. A
    2014

    A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function

    Katerina Nikolovska, Jana K Renke, Oliver Jungmann, Kay Grobe, Renato V Iozzo, Alina D Zamfir, Daniela G Seidler

    This study in mice investigated how the absence of a proteoglycan called decorin affects skin structure and function. Researchers found that mice lacking decorin had an altered composition of other sugar molecules (chon…

    extracellular matrixDecorinSLRPDermatan sulfateFibroblast growth factor
  4. A
    2014

    Vitamin C in the Treatment and/or Prevention of Obesity

    Diego Fernando GARCIA-DIAZ, Patricia LOPEZ-LEGARREA, Pablo QUINTERO, Jose Alfredo MARTINEZ

    In this 2014 narrative review, the authors examine the relationship between vitamin C and obesity. Obesity is often linked to oxidative stress, which can lead to other health issues like diabetes and cardiovascular dise…

    Oxidative stressAscorbic acidantioxidantbody weight
  5. A
    2014

    The cervical myodural bridge, a review of literature and clinical implications

    Dennis E Enix, Frank Scali, Matthew E Pontell

    This literature review examines the cervical myodural bridge, a soft tissue connection between deep suboccipital muscles and the dura mater surrounding the spinal cord. This bridge appears to anchor the spinal cord and…

    fasciarectus capitis posterior majordura materMyodural Bridgeobliquus capitis inferior
  6. A
    2014

    Primary frozen shoulder: brief review of pathology and imaging abnormalities

    Kazuya Tamai, Miwa Akutsu, Yuichiro Yano

    This narrative review examines the underlying pathology of primary frozen shoulder, a condition causing spontaneous pain and stiffness in the shoulder joint. The authors summarize evidence indicating that the main issue…

    frozen shoulderAdhesive capsulitisShoulder painTherapy
  7. A
    2014

    Fat Connected with the Primo Vascular System

    Kyoung-Hee Bae, Kwang-Sup Soh

    This research entry is currently available as a title only, so a detailed summary is not yet possible. The title, "Fat Connected with the Primo Vascular System," suggests an investigation into the relationship between a…

    fasciafatadipose tissueprimo vascular system (PVS)
  8. A
    2014

    Hyaluronan Synthase 2 Protects Skin Fibroblasts against Apoptosis Induced by Environmental Stress

    Yan Wang, Mark E Lauer, Sanjay Anand, Judith A Mack, Edward V Maytin

    Skin fibroblasts need to manage environmental stress, such as UV radiation. This study on mouse cells investigated how hyaluronan (HA) and the enzymes that produce it help fibroblasts survive. Researchers found that cel…

    Apoptosis; Caspase; Extracellular Matrix; Fibroblast; Hyaluronan; Skin; Stress.
  9. A
    2014

    Mechanotransduction and extracellular matrix homeostasis

    Jay D Humphrey, Eric R Dufresne, Martin A Schwartz

    Connective tissues are dynamic, constantly adapting even at rest. Cells within these tissues continually sense mechanical cues from their environment through a process called mechanotransduction. In response, they maint…

    fasciaextracellular matrixIntegrinsmechanosensingmechanoregulation
  10. A
    2014

    Treatment of Medial Tibial Stress Syndrome according to the Fascial Distortion Model: A Prospective Case Control Study

    Christoph Schulze, Susanne Finze, Rainer Bader, Andreas Lison

    This prospective case-control study investigated the Fascial Distortion Model (FDM) for treating medial tibial stress syndrome (MTSS), or shin splints. Researchers applied targeted manual techniques to the lower leg fas…

    Manual Therapyfasciaefascial distortion model
  11. A
    2014

    Clinical Relevance of Fascial Tissue and Dysfunctions

    Werner Klingler, M Velders, K Hoppe, M Pedro, Robert Schleip

    Fascia is a continuous network of connective tissue that supports the entire body. Traditionally seen as a passive structure, recent research shows it plays a more active role. Fascia contains contractile elements that…

    fasciaMyofascial painlumbar fasciadysfunction
  12. A
    2014

    Antioxidants in health and disease

    E Ginter, V Simko, V Panakova

    This narrative review summarizes research on antioxidants published since 2010. The main role of antioxidants is to neutralize reactive oxygen species (ROS), which are linked to conditions like cardiovascular disease, c…

    antioxidantsreactive oxygen species (ROS)vitamin C and Ecarotenoidspolyphenols
  13. A
    2014

    Lumbopelvic muscle activation patterns in three stances under graded loading conditions: Proposing a tensegrity model for load transfer through the sacroiliac joints

    Hamed Pardehshenas, Nader Maroufi, Mohammad Ali Sanjari, Mohamad Parnianpour, Stephen M Levin

    Researchers investigated how lumbopelvic muscles activate to stabilize the sacroiliac (SI) joints under different loads. They compared muscle activity in 30 men during two-legged and one-legged standing while holding we…

    fasciasacroiliac jointload transferwire-spoke wheel modelarch theory; Self-bracing
  14. A
    2014

    Definition of the To Be Named Ligament and Vertebrodural Ligament and Their Possible Effects on the Circulation of CSF

    Nan Zheng, Xiao-Ying Yuan, Yun-Fei Li, Yan-Yan Chi, Hai-Bin Gao, Xin Zhao, Sheng-Bo Yu, Hong-Jin Sui, John Sharkey

    In this cadaver study, researchers investigated connective tissue structures in the upper neck of 30 human specimens. They identified two specific ligaments, the 'to be named ligament' (TBNL) and the vertebrodural ligam…

    fasciadura materMyodural Bridgecerebrospinal fluid circulation
  15. A
    2014

    Specific Sizes of Hyaluronan Oligosaccharides Stimulate Fibroblast Migration and Excisional Wound Repair

    C Tolg, P Telmer, E Turley

    Hyaluronan (HA) is a molecule important for wound healing, and its effects appear to depend on its size. In this study using cell cultures and animal models, researchers investigated how specific, small fragments of HA…

    fasciahyaluronan molecular sizehyaluronan fragmentswound healing
  16. A
    2014

    The effectiveness of exercise interventions to prevent sports injuries: a systematic review and meta-analysis of randomised controlled trials

    Jeppe Bo Lauersen, Ditte Marie Bertelsen, Lars Bo Andersen

    This systematic review and meta-analysis examined 25 studies to evaluate which types of exercise best prevent sports injuries. The analysis included over 26,000 participants and data on more than 3,400 injuries. Researc…

    exercisesinjury prevention
  17. A
    2014

    Contractile elements in muscular fascial tissue – implications for in-vitro contracture testing for malignant hyperthermia

    K Hoppe, Robert Schleip, F Lehmann-Horn, Heike J€ager, Werner Klingler

    Malignant hyperthermia (MH) is a rare but serious reaction to general anesthesia, diagnosed using a test on a skeletal muscle biopsy. Since muscle samples also contain fascia, which has contractile cells called myofibro…

    myofibroblastsmalignant hyperthermiafascial tissuecontraction
  18. A
    2014

    Uptake and intracytoplasmic storage of pigmented particles by human CD34+ stromal cells/telocytes: endocytic property of telocytes

    Lucio Díaz-Flores, Ricardo Gutiérrez, M Pino García, Francisco J Sáez, Fernando Aparicio, Lucio Díaz-Flores Jr, Juan F…

    Researchers investigated whether a specific type of connective tissue cell, called a telocyte, could absorb foreign particles. They examined human colon tissue that had been injected with India ink as a surgical marker.…

    CD34+ stromal cells; colon; endocytosis; phagocytosis; skin; telocytes.
  19. A
    2014

    Ultrasound Elastography: The New Frontier in Direct Measurement of Muscle Stiffness

    Joline E Brandenburg, Sarah F Eby, Pengfei Song, Heng Zhao, Jeffrey S Brault, Shigao Chen, Kai-Nan An

    This 2014 review article describes ultrasound elastography, a technology that can directly measure the mechanical properties of tissue, such as muscle stiffness. The authors suggest that its real-time measurements can a…

    musclesElastographydiagnostic imagingelasticityhardness
  20. A
    2014

    Biotensegrity of the extracellular matrix: physiology, dynamic mechanical balance, and implications in oncology and mechanotherapy

    Irene Tadeo, Ana P Berbegall, Luis M Escudero,Tomás Álvaro, Rosa Noguera

    This 2014 review article explores the concept of biotensegrity, a principle where cells and tissues maintain structural integrity through a balance of tension and compression. This dynamic mechanical balance involves th…

    fasciaextracellular matrixcancerbiotensegritymechanotherapy
  21. A
    2014

    Whey protein hydrolysate augments tendon and muscle hypertrophy independent of resistance exercise contraction mode

    J Farup, S K Rahbek, M H Vendelbo, A Matzon, J Hindhede, A Bejder, S Ringgard, K Vissing

    This study investigated the effects of resistance training combined with either whey protein or a placebo on muscle and tendon growth. Twenty-two participants performed 12 weeks of knee extension training, using eccentr…

    patellar tendonstrength trainingeccentric trainingconcentric trainingrate of force development
  22. A
    2013

    Sensory findings after stimulation of the thoracolumbar fascia with hypertonic saline suggest its contribution to low back pain

    Andreas Schilder, Ulrich Hoheisel, Walter Magerl, Justus Benrath, Thomas Klein, Rolf-Detlef Treede

    This experimental study investigated the role of the thoracolumbar fascia as a potential source of low back pain. Researchers injected a pain-inducing saline solution into the fascia, back muscles, and subcutaneous tiss…

    fasciaThoracolumbar fascialow back painhypertonic salineerector spinae muscle
  23. A
    2013

    Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts

    Nanna Goldman, Devin Chandler-Militello, Helene Langevin, Maiken Nedergaard, Takahiro Takano

    This laboratory study investigated how certain molecules, called purines, affect human fibroblast cells. Previous research has shown that acupuncture can trigger the release of purines like ATP. The researchers exposed…

    fasciacytoskeletonacupunctureFibroblastscalcium signaling
  24. A
    2013

    Complete Obstetric Anal Sphincter Tear and Risk of Long-term Fecal Incontinence: A Cohort Study

    Mette M Soerensen, Steen Buntzen, Karl M Bek, Søren Laurberg

    This cohort study followed women for over 20 years to assess the long-term effects of complete anal sphincter tears during childbirth. Researchers compared 125 women who experienced such a tear with 238 women who gave b…

    Anal sphincter injury; Fecal incontinence; Quality of life.
  25. A
    2013

    Cellulite's aetiology: a review

    M de la Casa Almeida, Suarez Serrano, J Rebollo Roldán, J J Jiménez Rejano

    In this literature review, researchers examined the underlying causes of cellulite. They found that cellulite is a complex phenomenon with many interacting factors, rather than a single cause. The research points to wom…

    Connective tissuecellulites
  26. A
    2013

    Metabolic control of hyaluronan synthases

    Davide Vigetti, Manuela Viola, Evgenia Karousou, Giancarlo De Luca, Alberto Passi

    This narrative review explores how a cell's energy and nutritional status regulate the production of hyaluronan (HA), a key component of the extracellular matrix. HA is synthesized by enzymes called HAS, which require s…

    fasciaGlycosaminoglycanO-GlcNacylationUDP-GlcUAUDP-GlcNA
  27. A
    2013

    Primo Vascular System: Past, Present, and Future

    Byung-Cheon Lee, Walter J Akers, Xianghong Jing, M Isabel Miguel Perez, Yeonhee Ryu

    As only the title of this article was available, this summary is necessarily limited. The title, "Primo Vascular System: Past, Present, and Future," suggests this is a review article. It likely covers the history of the…

    fasciaprimo vascular systemeditorial
  28. A
    2013

    Training principles for fascial connective tissues: Scientific foundation and suggested practical applications

    Robert Schleip, Divo Gitta Müller

    Conventional sports training often emphasizes muscles, cardiovascular conditioning, and coordination, yet most overload injuries occur within the body's connective tissue network, or fascia. This review article proposes…

    fasciaStretchingfascial netCollagen renewalelastic recoil
  29. A
    2013

    Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions

    Kevin T Dicker, Lisa A Gurski, Swati Pradhan-Bhatt, Robert L Witt, Mary C Farach-Carson, Xinqiao Jia

    This review paper describes hyaluronan (HA), a simple sugar molecule found abundantly throughout the body's connective tissues. Despite its simple structure, HA has a surprising array of biological functions. It helps o…

    hyaluronanfasciawound healingsynthasehyaluronidase
  30. A
    2013

    Direct magnetic resonance (MR) shoulder arthrography: posterior approach under ultrasonographic guidance and abduction (PAUGA

    R F Grasso, E Faiella, P Cimini, R L Cazzato, G Luppi, F Martina, R Del Vescovo, B Beomonte Zobel

    This study evaluated a specific technique, called PAUGA, for injecting contrast dye into the shoulder joint before an MRI scan (MR arthrography). Researchers used ultrasound to guide a needle from the back of the should…

    ShoulderDirect MR arthrographyUS guidance
  31. A
    2013

    Human skeletal muscle ascorbate is highly responsive to changes in vitamin C intake and plasma concentrations

    Anitra C Carr, Stephanie M Bozonet, Juliet M Pullar, Jeremy W Simcock, Margreet C M Vissers

    This study investigated how vitamin C intake affects its concentration in human skeletal muscle. Researchers gave 36 men either half a kiwifruit or two kiwifruits daily for six weeks, as kiwifruit is a rich source of vi…

    Vitamin Cascorbate
  32. A
    2013

    Histological analysis of the rectus capitis posterior major’s myodural bridge

    Frank Scali, Matthew E Pontell, Dennis E Enix, Ewarld Marshall

    This cadaver study investigated a small tissue bridge between a suboccipital muscle (rectus capitis posterior major) and the dura mater, the protective covering of the spinal cord. Using microscopic analysis on tissue f…

    fasciacervical spinerectus capitis posterior majorMyodural Bridgecervical dura mater
  33. A
    2013

    Fascia Research Congress Evidence from the 100 year perspective of Andrew Taylor Still

    Thomas W Findley, Mona Shalwala

    This review paper examines research from the first three International Fascia Research Congresses through the perspective of Andrew Taylor Still, the founder of osteopathic medicine. Over a century ago, Still described…

    fasciaextracellular matrixfibroblastOsteopathic medicinefascia anatomy
  34. A
    2013

    Anatomic connections of the diaphragm: influence of respiration on the body system

    Bruno Bordoni, Emiliano Zanier

    This review article explains why the diaphragm muscle is a critical crossroads of information for the entire body. The authors describe its extensive anatomical, fascial, and neurological connections, which link it to s…

    fasciadiaphragmPelvisphrenic nervevagus nerve
  35. A
    2013

    Heparan sulfate in the nucleus and its control of cellular functions

    Mark D Stewart, Ralph D Sanderson

    This narrative review discusses the roles of heparan sulfate proteoglycans (HSPGs) inside the cell nucleus. These molecules are typically found on the cell surface and in the extracellular matrix, where they help regula…

    ProteoglycanSyndecan-1Nuclear localizationChromatin modificationProliferation
  36. A
    2013

    Nociception originating from the crural fascia in rats

    T Taguchi, M Yasui, A Kubo, M Abe, H Kiyama, A Yamanaka, K Mizumura

    This animal study investigated how the crural fascia, the connective tissue around the lower leg muscles, might be a source of pain signals in rats. Researchers found that this fascia is densely populated with nerve fib…

    fasciacrural fascianociceptorsactivity-dependent change in conduction velocity (ADCCV)twin pulse difference (TPD)
  37. A
    2013

    Plantar fascia anatomy and its relationship with Achilles tendon and paratenon

    Carla Stecco, Marco Corradin, Veronica Macchi, Aldo Morra, Andrea Porzionato, Carlo Biz, Raffaele De Caro

    This study investigated the detailed anatomy of the plantar fascia and its connection to the Achilles tendon. Dissections of human cadavers revealed that the fascia is more closely linked to the paratenon (the tendon's…

    hyaluronanfasciaFasciacyteachilles tendonparatenon
  38. A
    2013

    A Randomized Steady-State Bioavailability Study of Synthetic versus Natural (Kiwifruit-Derived) Vitamin C

    Anitra C Carr, Stephanie M Bozonet, Juliet M Pullar, Jeremy W Simcock, Margreet C M Vissers

    This randomized study investigated whether the body absorbs vitamin C from kiwifruit as effectively as from a synthetic supplement. Thirty-six young men received either half a kiwifruit or an equivalent dose (50 mg) vit…

    ascorbate; ascorbic acid; human; plasma; urine; semen; leukocytes; skeletal muscle
  39. A
    2013

    A pilot study of myofascial release therapy compared to Swedish massage in Fibromyalgia

    Ginevra Liptan, Scott Mist, Cheryl Wright, Anna Arzt, Kim Dupree Jones

    This small pilot study compared the effects of myofascial release (MFR) and Swedish massage on women with fibromyalgia. Participants received either MFR or Swedish massage for 90 minutes weekly over four weeks. While bo…

    fasciaMyofascial releaseFibromyalgiamassage therapycentral sensitization
  40. A
    2013

    The Primo Vascular System as a New Anatomical System

    Miroslav Stefanov, Michael Potroz, Jungdae Kim, Jake Lim, Richard Cha, Min-Ho Nam

    This review paper proposes the existence of a "primo vascular system" (PVS) as the physical, anatomical basis for the meridian system of traditional Eastern medicine. According to the authors, this previously unknown sy…

    fasciaEvolutioncirculatory systemnew morphologicalfunctional theory
  41. A
    2013

    Cellular Control of Connective Tissue Matrix Tension

    H M Langevin, M Nedergaard, A Howe

    This review article explores how fibroblasts, the cells within connective tissue, actively help regulate tissue tension. Traditionally, the mechanical properties of connective tissue have been attributed to its passive…

    Connective tissuefibroblastmechanicalatpcytoskeleton
  42. A
    2013

    Visceral and Somatic Disorders: Tissue Softening with Frequency-Specific Microcurrent

    Carolyn R McMakin, James L Oschman

    This review article explores a technique called Frequency-Specific Microcurrent (FSM), which uses microampere-level electrical currents to treat various health conditions. A consistent finding is a rapid and palpable so…

    fasciafrequency-specific microcurrentvisceral diseasesomatic disease
  43. A
    2013

    Telocytes: ultrastructural, immunohistochemical and electrophysiological characteristics in human myometrium

    Sanda M Cretoiu, Dragos Cretoiu, Adela Marin, Beatrice Mihaela Radu, Laurentiu M Popescu

    This study identifies a specific cell type, telocytes, within the muscular wall of both the pregnant and non-pregnant human uterus. Researchers found that these cells have a different structure depending on whether the…

    telocytesuterine
  44. A
    2013

    Histological examination of the human obliquus capitis inferior myodural bridge

    Matthew E Pontella, Frank Scali, Dennis E Enix, Patrick J Battaglia, Ewarld Marshall

    This cadaver study examined the connection between a deep neck muscle, the obliquus capitis inferior (OCI), and the dura mater, the tough outer layer covering the spinal cord. Researchers dissected tissue from eight cad…

    fasciacervical spineMyodural Bridgeobliquus capitis inferiordura
  45. A
    2013

    Dosed Myofascial Release in Three-Dimensional Bioengineered Tendons: Effects on Human Fibroblast Hyperplasia, Hypertrophy, and Cytokine Secretion

    Thanh V Cao, Michael R Hicks, David Campbell, Paul R Standley

    This laboratory study investigated how different amounts and durations of simulated myofascial release (MFR) affect lab-grown human tendon tissue. Researchers applied varying degrees of stretch for different lengths of…

    fasciamusculoskeletal manipulationsFibroblaststendons
  46. A
    2013

    Applications and Emerging Trends of Hyaluronic Acid in Tissue Engineering, as a Dermal Filler, and in Osteoarthritis Treatment

    Amir Fakhari, Cory Berkland

    This narrative review summarizes knowledge about hyaluronic acid (HA), a naturally occurring polymer found in the body's connective tissues and fluids. The authors describe how HA contributes to the structural propertie…

    fasciaHyaluronic acidcrosslinkingdermal fillerviscosupplement
  47. A
    2013

    Helical Structure of the Cardiac Ventricular Anatomy Assessed by Diffusion Tensor Magnetic Resonance Imaging With Multiresolution Tractography

    Ferran Poveda, Debora Gil, Enric Marti, Albert,aluz, Manel Ballester, Francesc Carreras

    In this animal study, researchers used advanced magnetic resonance imaging (MRI) and computer modeling to visualize the complex fiber structure of the heart muscle in dogs. They developed an automated method to trace th…

    fasciaheartifdfusion magnetic resonance imagingdiffusion tractographyhelical heart
  48. A
    2013

    Earthing (Grounding) the Human Body Reduces Blood Viscosity—a Major Factor in Cardiovascular Disease

    Gaétan Chevalier, Stephen T Sinatra, James L Oschman, Richard M Delany

    This small study investigated how direct physical contact with the earth, known as 'grounding' or 'earthing', affects blood properties. Ten healthy participants were grounded for two hours using conductive patches on th…

    fasciaearthinggroundingearth surface electronscardiovasclar disease
  49. A
    2013

    Molecular assembly and mechanical properties of the extracellular matrix: A fibrous protein perspective

    Lisa D Muiznieks, Fred W Keeley

    This review article examines the extracellular matrix (ECM), the dynamic network of molecules surrounding our cells. The authors focus on fibrous proteins like collagen and elastin, which form the structural backbone of…

    fasciaextracellular matrixcollageneastinself-assembly
  50. A
    2012

    Massage Therapy Attenuates Inflammatory Signaling After Exercise-Induced Muscle Damage

    Justin D Crane, Daniel I Ogborn, Colleen Cupido, Simon Melov, Alan Hubbard, Jacqueline M Bourgeois, Mark A Tarnopolsky

    This study investigated how massage therapy affects skeletal muscle at a cellular level after exercise-induced damage. Researchers took muscle biopsies from 11 young men after an intense workout; one leg received 10 min…

    fasciamassage therapyinflammatory cytokinesstretchstrain
  51. A
    2012

    CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

    Kenneth E Lipson, Carol Wong, Yuchin Teng, Suzanne Spong

    Fibrosis is a process of excessive connective tissue formation, leading to scarring and stiffness in organs. A protein called Connective Tissue Growth Factor (CTGF) plays a central role in driving this process. This res…

    extracellular matrixfibrosisfascia CTGFtissue remodeling
  52. A
    2012

    A RHAMM Mimetic Peptide Blocks Hyaluronan Signaling and Reduces Inflammation and Fibrogenesis in Excisional Skin Wounds

    Cornelia Tolg, Sara R Hamilton, Ewa Zalinska, Lori McCulloch, Ripal Amin, Natalia Akentieva, Francoise Winnik, Rashmin…

    In this animal study, researchers investigated how to reduce scarring during skin wound healing. They developed a peptide, P15-1, designed to interfere with signals from fragmented hyaluronan, a molecule involved in inf…

    hyaluronaninflammationfasciaextracellular matrixfibrosis
  53. A
    2012

    Hyaluronic acid, A key molecule in skin aging

    Eleni Papakonstantinou, Michael Roth, George Karakiulakis

    This review article discusses the role of hyaluronic acid (HA) in skin aging. The authors explain that youthful skin's plumpness and resilience are largely due to its high water content, which HA is uniquely able to ret…

    CD44fasciaHyaluronic acidhyaluronic acid synthaseshyaluronidases
  54. A
    2012

    A theoretical framework for the role of fascia in manual therapy

    Nigel Simmonds, Peter Miller, Hugh Gemmell

    This theoretical paper explores why different types of manual therapy, such as soft tissue work and joint manipulation, often seem to produce similar results. The authors compare these approaches based on their effects…

    fasciaManual TherapyMyofascialManipulationautonomic nervous system
  55. A
    2012

    Human myometrium – the ultrastructural 3D network of telocytes

    Sanda M Cretoiu, Dragos Cretoiu, Laurentiu M Popescu

    This study examined a relatively new type of cell, the telocyte, within the human myometrium, the muscular layer of the uterus. Using advanced microscopy, researchers visualized these cells and their very long extension…

    telocytes ! telopodes ! podoms ! podomers ! human uterus ! extracellular vesicles
  56. A
    2012

    Mechanical properties of human patellar tendon at the hierarchical levels of tendon and fibril

    René B Svensson, Philip Hansen, Tue Hassenkam, Bjarki T Haraldsson, Per Aagaard, Vuokko Kovanen, Michael Krogsgaard, Mi…

    Researchers investigated how the mechanical properties of the whole human patellar tendon compare to its individual collagen fibrils. They tested whole tendons in living subjects and then tested isolated fibrils from th…

    atomic force microscopy; collagen; fibril dimensions; modulus; toe region
  57. A
    2012

    Strain hardening of fascia: Static stretching of dense fibrous connective tissues can induce a temporary stiffness increase accompanied by enhanced matrix hydration

    Robert Schleip, Lutz Duerselen, Andry Vleeming, Ian L Naylor, Frank Lehmann-Horn, Adjo Zorn, Heike Jaeger, Werner Kling…

    This study investigated why fascia sometimes gets stiffer after being stretched and then rested, a phenomenon called strain hardening. Researchers stretched fascia samples from mice and pigs, finding that after a 15-min…

    Lumbar fascia; Paraspinal tissues; Stiffness; Hydration; Stretching
  58. A
    2012

    Mathematical model of fiber orientation in anisotropic fascia layers at large displacements

    Hans Chaudhry, Max Roman, Antonio Stecco, Thomas Findley

    Researchers developed a mathematical model to better understand how collagen fibers within fascia change their orientation when the tissue is stretched. The model suggests that fibers already angled away from the direct…

    Fascial; Reinforcement; Collagen fibers; Re-orientation; Tension
  59. A
    2012

    An MRI Study of Symptomatic Adhesive Capsulitis

    Wen Zhao, Xiaofeng Zheng, Yuying Liu, Wenlu Yang, Vardan Amirbekian, Luis E Diaz, Xudong Huang

    This study used magnetic resonance imaging (MRI) to compare the shoulders of 60 patients with clinically diagnosed adhesive capsulitis (frozen shoulder) to 60 healthy control subjects. Researchers found significant diff…

    Adhesive capsulitisShoulderMagnetic resonance imaging
  60. A
    2012

    The thoracolumbar fascia: anatomy, function and clinical considerations

    Frank H Willard, Andry Vleeming, M D Schuenke, L Danneels, Robert Schleip

    This overview paper examines the anatomy and function of the thoracolumbar fascia (TLF), the complex sheet of connective tissue in the lower back. The authors describe its multiple layers, which separate and connect the…

    fasciathoracolumbarfascia