Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- C2007
Cell–Matrix Adhesion
Allison L Berrier, Kenneth M YamadaThe connection between cells and their surrounding extracellular matrix (ECM) is fundamental to how tissues are built and function. This matrix, composed of collagen and other proteins, not only provides structural supp…
Integrinscell adhesion - A2007
The Myofibroblast One Function, Multiple Origins
Boris Hinz, Sem H Phan, Victor J Thannickal, Andrea Galli, Marie-Luce Bochaton-Piallat, Giulio GabbianiThis 2007 review article discusses the myofibroblast, a cell type crucial for wound healing but also implicated in fibrosis, or pathological scarring. The authors highlight that while myofibroblasts perform similar func…
fibrosisMyofibroblast - B2007
Functional Anatomy of the Female Pelvic Floor
James A Ashton-Miller, John O L DeLanceyThis review of the female pelvic floor's functional anatomy explains how it prevents incontinence and organ prolapse. It details two key systems: sphincters that keep the urethra closed, and a supportive "hammock" of mu…
functional anatomy; female pelvic floor; levator ani muscles; urethra; prolapse; incontinence; vaginal birth - A+++2007
Can Electrons Act as Antioxidants? A Review and Commentary
James OschmanThis narrative review explores the hypothesis that direct physical contact with the earth, known as "earthing" or "grounding," can provide health benefits. The author suggests that modern lifestyles, with insulated foot…
earthinggroundingantioxidantsfree radicals - A+++2007
A driving force for change: interstitial flow as a morphoregulator
Joseph M Rutkowski, Melody A SwartzThis narrative review explores how the slow movement of fluid through the extracellular matrix, known as interstitial flow, acts as a crucial regulator of cell behavior and tissue structure. Driven by pressure gradients…
Morphologyinterstitial flow - A2007
Asymmetric Sphincter Innervation is Associated With Fecal Incontinence After Anal Sphincter Trauma During Childbirth
Beate M Wietek, Heidemarie Hinninghofen, Ekkehard C Jehle, Paul Enck, Heiko B FranzResearchers investigated if uneven nerve signals (asymmetry) to the anal sphincter muscles are linked to fecal incontinence after childbirth. They compared three groups: pregnant women who had not given birth, women aft…
anal incontinence; asymmetry; birth trauma; innervation; perineal laceration; vaginal delivery - A+++2007
Vitamin D Deficiency
Michael F HolickThis 2007 publication by Michael F. Holick addresses the topic of vitamin D deficiency. As the full text has not yet been analyzed, this summary is based on the title alone. Further details about the specific findings a…
vitamin D25-hydroxyvitamin D3 - A2007
Anatomy of the deep fascia of the upper limb. Second part: study of innervation
Carla Stecco, O Gagey, A Belloni, A Pozzuoli, A Porzionato, V Macchi, R Aldegheri, R De Caro, V DelmasThis anatomical study examined the nerve supply within the deep fascia of the upper limb. Researchers analyzed tissue samples from 20 arms, focusing on five specific areas including the brachial fascia and the flexor re…
fasciainnervationproprioceptionmotor coordinationruffini corpuscles - A2007
Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering
Kevin K Parker, Donald E IngberThis narrative review explores the challenges of engineering artificial heart tissue. The heart functions across vast scales of time and space, from tiny ion channels to the whole organ's pumping action. The authors sug…
fasciaextracellular matrixcytoskeletonmechanotransductionmyocardial cell - A++2007
Interstitial Flow and Its Effects in Soft Tissues
Melody A Swartz, Mark E FleuryThis 2007 review article summarizes knowledge about interstitial flow, which is the movement of fluid in the spaces between cells in the body's soft tissues. The authors describe how this flow is critical for tissue dev…
mechanobiologyDrug deliverymorphogenesistransportpermeability - B2007
Epimuscular myofascial force transmission between antagonistic and synergistic muscles can explain movement limitation in spastic paresis
Peter A HuijingThis review, which includes new animal data, examines how muscles transmit force through their surrounding connective tissue sheaths (fascia). The research indicates that force can be transmitted between all muscles wit…
MyofascialcontractureMyotendinousForce transmissionProximo-distal force difference - A+2007
Breathing exercises with vagal biofeedback may benefit patients with functional dyspepsia
INA E HJELLAND, SVEN SVEBAK, ARNOLD BERSTAD, GEIR FLATAB, TRYGVE HAUSKENFunctional dyspepsia (FD) is often associated with low vagus nerve tone. This study investigated whether breathing exercises with biofeedback could help. Forty patients with FD were divided into two groups; one group pr…
Biofeedbackbreathing exercisesfunctional dyspepsiavagal tone