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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 997–1,008 of 1,131 studies · page 84/95
  1. B
    2008

    Myofascial Force Transmission via Extramuscular Pathways Occurs between Antagonistic Muscles

    Peter A Huijing, Guus C Baan

    In this experimental study, researchers investigated whether opposing (antagonistic) muscles act independently or influence each other through their fascial connections. By lengthening a lower leg muscle (extensor digit…

    Connective tissueProximo-distal force differenceAnterior crural compartmentAnterior tibial muscleExtensor digitorum longus muscle
  2. A
    2008

    Tensegrity-Based Mechanosensing from Macro to Micro

    Donald E Ingber

    This review article, based on a lecture, explores how cells convert mechanical signals into biochemical responses. The author proposes that the body uses "tensegrity" (tensional integrity) principles, where interconnect…

    fasciaextracellular matrixTensegritycytoskeletonmechanotransduction
  3. A++
    2008

    Stability, continence and breathing: The role of fascia following pregnancy and delivery

    D G Lee, L J Lee, L McLaughlin

    Many women experience pelvic girdle pain, incontinence, or breathing issues after pregnancy and delivery. This paper explores the role of the trunk's muscles and fascia in stability, continence, and respiration. The aut…

    Linea alba; Diastasis rectus abdominis; Pelvic floor; Paravaginal defects; Breathing; Hypocapnia; fascia
  4. 1A+
    2008

    Expression of the endocannabinoid system in fibroblasts and myofascial tissues

    J M McPartland

    This narrative review investigates the endocannabinoid (eCB) system, a network in the body similar to the endorphin system that helps regulate pain and inflammation. Using a bioinformatics approach to analyze existing d…

    Cannabinoids; Endocannabinoids; Ajulemic acid; Osteopathic medicine; Chiropractic; Myofascial release; Fibromyalgia; Myofascial trigger points; Biodynamics
  5. A++
    2008

    Humoral phototransduction: Light transportation in the blood, and possible biological effects

    F Grass, S Kasper

    In this theoretical paper, researchers propose a model called 'humoral phototransduction' to explain how light might affect the body beyond the eyes. They observed that blood plasma, and particularly the protein albumin…

    fasciabiophotonsultraweak photonshumoral phototransduction
  6. B
    2008

    The inflammatory response to cell death

    K L Rock, H Kono

    This 2008 review article explores how the body responds when cells die from injury rather than infection. Such cell death triggers an inflammatory response that is essential for host defense and tissue repair. However,…

    inflammationNecrosisdangertoll-like receptorscytokines
  7. A
    2008

    Mechanotransduction – a field pulling together?

    Christopher S Chen

    In this 2008 review article, the author discusses mechanotransduction, the process by which cells convert mechanical forces into biochemical signals. Cells are constantly subjected to forces, both from external pressure…

    fasciastiffnessmechanobiologycell adhesionmechanical force
  8. A
    2008

    Dorsal horn neurons having input from low back structures in rats

    T Taguchi, U Hoheisel, S Mense

    In this animal study, researchers in rats investigated how spinal cord nerve cells (dorsal horn neurons) process signals from the low back. They found that these neurons often receive input from several different tissue…

    fascialow back painmultifidus muscledorsal horn neuronsnerve growth factor (NGF)
  9. A
    2008

    Magnetic Resonance Imaging of Adhesive Capsulitis: Correlation with Clinical Staging

    Carolyn M Sofka, Gina A Ciavarra, Jo A Hannafin, Frank A Cordasco, Hollis G Potter

    This study investigated whether standard magnetic resonance imaging (MRI) can be used to diagnose and stage adhesive capsulitis (frozen shoulder). Researchers retrospectively reviewed MRI scans from 46 patients with an…

    Adhesive capsulitisShoulderMagnetic resonance imaging
  10. A++
    2007

    Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

    Qi Chen, Michael Graham Espey, Andrew Y Sun, Je-Hyuk Lee, Murali C Krishna, Emily Shacter, Peter L Choyke, Chaya Pooput…

    High-dose intravenous Vitamin C (ascorbate) can selectively kill some cancer cells without harming normal cells. Researchers have proposed this is because ascorbate acts as a prodrug, creating hydrogen peroxide and othe…

    ascorbic acid " cancer " vitamin C " pharmacokinetics
  11. A++
    2007

    A suspensory system for the sacrum in pelvic mechanics: Biotensegrity

    Stephen Levin

    This 2007 publication by Stephen Levin, available only by title, appears to describe a model for understanding the mechanics of the pelvis. The title suggests a 'suspensory system' for the sacrum, framing its function w…

    biotensegrityPelvisKinematicssacrummovement
  12. B
    2007

    Cytokines, Inflammation and Pain

    J-M Zhang, J An

    This review chapter describes the role of cytokines—small proteins that cells use for communication—in inflammation and pain. The authors explain that there are both pro-inflammatory and anti-inflammatory types of cytok…

    inflammationcytokinepainhyperalgesia