Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2014
Low-intensity vibration improves angiogenesis and wound healing in diabetic mice
Eileen M Weinheimer-Haus, Stefan Judex, William J Ennis, Timothy J KohThis animal study investigated if whole-body low-intensity vibration (LIV) could improve chronic wound healing in diabetic mice. Mice with surgical wounds received either 30 minutes of daily vibration or a sham treatmen…
wound healingvibrationsdiabetic wounds - A+2014
Dietary Hyaluronic Acid Migrates into the Skin of Rats
Mariko Oe, Koichi Mitsugi, Wataru Odanaka, Hideto Yoshida, Ryosuke Matsuoka, Satoshi Seino, Tomoyuki Kanemitsu, Yasunob…In this animal study, researchers investigated whether orally ingested hyaluronic acid could reach the skin in rats. Using a radio-labeled version of hyaluronic acid, they tracked its path through the body after rats we…
Orally HAHA supplement - A++2014
Vibration therapy: clinical applications in bone
William R Thompson, Sherwin S Yen, Janet RubinThis review article explores vibration therapy as a way to mimic the positive effects of physical activity on bone and muscle, especially for frail individuals who cannot exercise. Animal and human studies suggest that…
low-intensity vibration; mesenchymal stem cells; osteocyte; osteoporosis - A2014
Mapping Sensory Nerve Communications Between Peripheral Nerve Territories
ADIL LADAK, R SHANE TUBBS, ROBERT J SPINNERIn this literature review, researchers examined the traditional maps of skin sensation, known as dermatomes. They searched for evidence of direct communications between sensory nerves from different, adjacent spinal ner…
dermatomes; nerve; communications; map; cutaneous; sensory - A++2014
Ultra-weak photon emission from biological samples: Definition, mechanisms, properties, detection and applications
Michal Cifra, Pavel PospíšilThis review article summarizes the current understanding of ultra-weak photon emission (UPE), a faint light naturally produced by living organisms. This light, a form of chemiluminescence, is generated during normal met…
biophotonsChemiluminescenceOxidative stressSinglet oxygenCharge coupled device - A++2014
Towards whole-body ultra-weak photon counting and imaging with a focus on human beings: A review
Roeland Van Wijk, Eduard P A Van Wijk, Herman A van Wietmarschen, Jan van der GreefIn this review article, the authors describe the history and development of research into ultra-weak photon emission (UPE), the faint light naturally emitted by the human body. The scientific understanding of this pheno…
Ultra-weak photon emissionBiophotonReactive oxygen speciesSystems biologyHuman - B2014
Altered Gene Transcription in Human Cells Treated with Ludox® Silica Nanoparticles
Caterina Fede, Caterina Millino, Beniamina Pacchioni, Barbara Celegato, Chiara Compagnin, Paolo Martini, Francesco Selv…This in vitro study investigated how human lung cells react to exposure to Ludox® silica nanoparticles, which are common in industrial and biomedical applications. Using genetic analysis, researchers observed that the c…
nanoparticles (NPs); cell toxicity; microarray gene expression; pathway analysis - A++2014
Spatiotemporal Imaging of Glutamate-Induced Biophotonic Activities and Transmission in Neural Circuits
Rendong Tang, Jiapei DaiThis study on mouse brain tissue investigated biophotons, which are ultra-weak light emissions from biological systems. Researchers found that applying the neurotransmitter glutamate caused a significant and long-lastin…
fasciabiophotonsultraweak photons - A2014
Whey protein hydrolysate augments tendon and muscle hypertrophy independent of resistance exercise contraction mode
J Farup, S K Rahbek, M H Vendelbo, A Matzon, J Hindhede, A Bejder, S Ringgard, K VissingThis study investigated the effects of resistance training combined with either whey protein or a placebo on muscle and tendon growth. Twenty-two participants performed 12 weeks of knee extension training, using eccentr…
patellar tendonstrength trainingeccentric trainingconcentric trainingrate of force development - B2014
Neuroreceptor Activation by Vibration-Assisted Tunneling
Ross D Hoehn, David Nichols, Hartmut Neven, Sabre KaisThis theoretical study used quantum chemical modeling to explore how receptors in the nervous system get activated. The researchers propose a model where a molecule's specific vibrations, like a musical key, may be what…
fasciag-proteinpharmacologyGPCRssilicopotency - A++2014
Age- and diabetes-related nonenzymatic crosslinks in collagen fibrils: Candidate amino acids involved in Advanced Glycation End-products
Alfonso Gautieri, Alberto Redaelli, Markus J Buehler, Simone VesentiniAdvanced Glycation End-products (AGEs) are harmful crosslinks that form in collagen with aging and in diabetes, making tissues stiffer. However, the exact location of these crosslinks has been unclear. In this theoretic…
Advanced glycation end-products; Ageing; Atomistic simulations; Collagen; Crosslinks; Diabetes. - A2014
Deformations Experienced in the Human Skin, Adipose Tissue, and Fascia in Osteopathic Manipulative Medicine
Hans Chaudhry, Bruce Bukiet, Zhiming Ji, Antonio Stecco, Thomas W FindleyThis study used a mathematical model to investigate how forces from manual therapy affect the skin, adipose tissue, and fascia. The researchers aimed to understand how much each layer deforms under compression and shear…
fasciaosteopathyManual Therapy