Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2017
Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis
Gregory Shaw, Ann Lee-Barthel, Megan L R Ross, Bing Wang, Keith BaarIn a small study involving eight healthy men, researchers investigated the effect of vitamin C-enriched gelatin supplementation before exercise. Participants who consumed 15 grams of gelatin one hour before a short, int…
Bonetendonexerciseligamentreturn to play - A2017
Semimembranosus Muscle Injuries In Sport. A Practical MRI use for Prognosis
Ramon Balius, Mireia Bossy, Carles Pedret, Lluis Capdevila, Xavier Alomar, Bryan Heiderscheit, Gil RodasThis retrospective study investigated whether MRI scans could help predict recovery time for athletes with injuries to the semimembranosus, one of the hamstring muscles. Researchers analyzed MRI scans from 19 athletes,…
MRIreturn to playsemimembranosushamstring injuries - A+++2017
Proinflammatory Cytokines and Oxidative Stress Decrease the Transport of Dopamine Precursor Tyrosine in Human Fibroblasts
Ravi Vumma, Jessica Johansson, Nikolaos VenizelosThis laboratory study investigated how inflammation and oxidative stress affect the transport of the amino acid tyrosine in human fibroblasts, a type of connective tissue cell. Tyrosine is a crucial precursor for the ne…
Dopamine precursor; Human fibroblasts; Neuropsychiatric disorders; Oxidative stress; Proinflammatory cytokines; Tyrosine transport. - B2017
Acoustic wave therapy for cellulite, body shaping and fat reduction
Doris Hexsel, Fernanda Oliveira Camozzato, Aline Flor Silva, Carolina SiegaThis study evaluated the efficacy of acoustic wave therapy (AWT) for cellulite and body shaping. Thirty women with moderate to severe cellulite underwent 12 treatment sessions on the glutes and thighs over six weeks. Th…
Acoustic wave therapy; body shaping; cellulite; Cellulite Severity Scale; subcutaneous fat tissue thickness - B2017
Mechanical Properties of the Cytoskeleton and Cells
A F Pegoraro, P Janmey, D A WeitzIn this review article, the authors describe the cytoskeleton, which is the cell's main mechanical structure. It is a complex and dynamic network of biopolymers that includes microtubules, actin, and intermediate filame…
cytoskeletonmicrotubulesactin filamentintermediate filament - B2017
Stretching Reduces Skin Thickness and Improves Subcutaneous Tissue Mobility in a Murine Model of Systemic Sclerosis
Y Xiong, L Berrueta, K Urso, Sara Olenich, Igla Muskaj, G J Badger, A Aliprantis, R Lafyatis, H M LangevinThis animal study investigated the effects of stretching on systemic sclerosis, a condition that causes skin inflammation and fibrosis. Using a mouse model of the disease, researchers found that ten minutes of daily str…
inflammationfibrosisSystemic sclerosisStretchingscleroderma - A2017
The Lumbodorsal Fascia as a Potential Source of Low Back Pain: A Narrative Review
Jan Wilke, Robert Schleip, Werner Klingler, Carla SteccoThis narrative review examines the role of the lumbodorsal fascia as a potential source of low back pain. Research shows this fascia contains pain-sensing nerve endings, which may be morphologically altered in people wi…
fasciaNociceptionlow back painlumbodorsal fascia - B2017
Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism
Rosilene Cristina Rossetto Burgos, Johannes Cornelius Schoeman, Lennart Jan van Winden, Kateřina Červinková, Rawi Ramau…This laboratory study investigated a method for measuring oxidative stress, a process linked to many diseases. Researchers used a technique called ultra-weak photon emission (UPE) to monitor human cells in a dish after…
Ultra-weak photon emission - A+++2017
The deep fascia and retinacula of the equine forelimb - structure and innervation
Aleksandra Skalec, Monika EgerbacherThis study investigated the deep fascia and its reinforcements (retinacula) in the equine forelimb using anatomical dissection and microscopic analysis. The researchers found that horse fascia is structurally similar to…
equine; fascia; forelimb; innervation; retinaculum; structure - A++2017
Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes
Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M ShawThis study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…
Vitamin CsepsisIntensive careHypovitaminosis CCritical illness - A+++2017
Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats
Victor Fabricio, Jorge Camargo Oishi, Bruna Gabriele Biffe, Leandro Dias Gonçalves Ruffoni, Karina Ana da Silva, Keico…This animal study on rats investigated how resveratrol affects blood pressure and vascular function during estrogen deficiency, mimicking post-menopausal conditions. Researchers found that a lack of estrogen led to high…
blood pressureresveratrolPostmenopause - C2017
Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface
KA Khan, AJ Naylor, A Khan, PJ Noy, M Mambretti, P Lodhia, J Athwal, A Korzystka, CD Buckley, BE Willcox, F Mohammed ,…Researchers investigated how certain proteins interact to form new blood vessels, a process called angiogenesis that is crucial for tumor growth. This study, which included lab experiments and mouse models, identified a…
fasciaextracellular matrixendotheliumC-type lectintumor angiogenesis