Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2018
Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis
Jing LiThis commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…
meta-analysisVitamin CAscorbic acidsepsisSevere sepsis - A++2018
Vitamin C – A new player in regulation of the cancer epigenome
Linn Gillberg, Andreas D Ørskov, Minmin Liu, Laurine B S Harsløf, Peter A Jones, Kirsten GrønbækThis narrative review explores the emerging role of vitamin C in cancer treatment, particularly in relation to epigenetics. The authors note that vitamin C is crucial for enzymes that help regulate gene expression, and…
Ascorbic acid; Cancer treatment; Epigenetics; Hematological malignancies; Vitamin C - A2018
Frontiers in fascia research
Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…
fasciaultrasound.Pain therapySport sciencesIndentometry - A2018
Morphometric and dynamic measurements of muscular fascia in healthy individuals using ultrasound imaging: a!summary of the discrepancies and gaps in the current literature
Caterina Fede, Nathaly Gaudreault, Chenglei Fan, Veronica Macchi, Raffaele De Caro, Carla SteccoThis narrative review examined existing research on using ultrasound to measure muscular fascia in healthy people. The authors found that while ultrasound is a useful tool, the research is concentrated on a few specific…
Fascia · Ultrasound imaging · Thickness · Strain · Motion - A2018
Therapeutic potentials of superoxide dismutase
H YounusThis narrative review explores the therapeutic potential of superoxide dismutases (SODs), a group of enzymes that serve as a crucial antioxidant defense against oxidative stress in the body. The author discusses the rol…
Oxidative stresssuperoxide dismutasetherapeutic effects - A2018
Measuring the Human Ultra-Weak Photon Emission Distribution Using an Electron-Multiplying, Charge-Coupled Device as a Sensor
Fernando Ortega-Ojeda, Matías Calcerrada, Alejandro Ferrero, Joaquín Campos, Carmen Garcia-RuizLiving systems, including humans, emit an extremely faint light called ultra-weak photon emission (UPE). This light is thought to be a byproduct of metabolic processes, particularly those involving reactive oxygen speci…
ultra-weak photon emission; spectrometer; measurement; electron multiplying charge coupled device sensor; liquid crystal tunable filter - A++2018
Release of fascial compartment boundaries reduces muscle force output
Roy J Ruttiman, David A Sleboda,, Thomas J RobertsIn this animal study, researchers investigated how the fascial sheets that enclose muscles affect their function. They surgically removed the fascia from a wing muscle in wild turkeys to see how it changed the muscle's…
Muscletendoncompartmentfasciotomyintramuscular pressure - A2018
Effectiveness of Physiotherapy Treatment for Urinary Incontinence in Women: A Systematic Review
Remedios López-Liria, María de los Ángeles Varverde-Martínez, David Padilla-Góngora, Patricia Rocamora-PérezThis systematic review evaluated the effectiveness of different physiotherapy techniques for treating urinary incontinence in women. Researchers analyzed 16 studies covering methods such as pelvic floor exercises, vagin…
physiotherapywomenurinary incontinencepelvic floor muscle - A2018
Biotensegrity and myofascial chains: A global approach to an integrated kinetic chain
S L Dischiavi, A A Wright, E J Hegedus, C M BleakleyThis theoretical paper proposes a holistic way to understand human movement, contrasting it with the traditional approach of studying body parts in isolation. The authors suggest a model based on "biotensegrity," where…
RehabilitationbiotensegrityMuscular chainsDynamic knee valgusHip - A++2018
Subcutaneous adipose tissue therapy reduces fat by dual X-ray absorptiometry scan and improves tissue structure by ultrasound in women with lipoedema and Dercum disease
M Ibarra, A Eekema, C Ussery, D Neuhardt, K Garby, K L HerbstThis small study investigated a non-surgical therapy for subcutaneous adipose tissue in seven women with lipoedema or Dercum disease. Over four weeks of treatment, participants experienced significant reductions in weig…
lipoedemaDercum diseasesubcutaneous adipose tissue. - A+++2018
Structure and Distribution of an Unrecognized Interstitium in Human Tissues
Petros C Benias, Rebecca G Wells, Bridget Sackey-Aboagye, Heather Klavan, Jason Reidy, Darren Buonocore, Markus Miranda…Using a new imaging technique, researchers identified a previously unrecognized, fluid-filled structure within the body's connective tissues. This network of collagen bundles and fluid-filled spaces, which they term the…
interstitiuminterstitial spacesfascia fluid - A2018
Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C
Shinjini Ganguly, Ayan Chandra, Indu B ChatterjeeIn this animal study, researchers investigated how cigarette smoke might cause invasive cancer of the renal pelvis and if vitamin C could offer protection. They found that when guinea pigs were exposed to cigarette smok…
Invasive cancer of the renal pelvis Cigarette smoke Vitamin C Oxidative damage Persistent EGFR signaling Cell cycle deregulation