Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 385–396 of 1,131 studies · page 33/95

A++
2019
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
Alpha A Fowler, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday, Bernard Fisher, Leroy…
This randomized controlled trial investigated whether intravenous vitamin C could help patients with sepsis and severe acute respiratory failure. Researchers gave 167 patients either a high-dose vitamin C infusion or a…
sepsisintravenous vitamin C
A+++
2019
Cannabidiol differentially regulates basal and LPS-induced inflammatory responses in macrophages, lung epithelial cells, and fibroblasts
Thivanka Muthumalage, Irfan Rahman
This laboratory study investigated how cannabidiol (CBD) influences inflammatory responses in lung epithelial cells, fibroblasts, and immune cells. The researchers found that CBD can reduce inflammation triggered by ext…
CBD; E-cigarette; E-liquid; Lung; Marijuana; Vaping
A
2019
Fascial Nomenclature: An Update
Bruno Bordoni, Stevan Walkowski, Bruno Morabito, Matthew A Varacallo
This review article discusses the ongoing challenge of creating a single, comprehensive definition for fascia. The authors argue that different scientific and clinical fields view fascia through their own unique lenses,…
fasciamechanotransductionMyofascialOsteopathicphysiotherapy
A++
2019
8 natural supplements to help fight inflammation
Zawn Villines
Inflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…
inflammationomega-3curcumin
A
2019
Putative Primo-Vascular System in Rabbit Placenta
Fatma El-Zahraa A Mustafa
In this animal study, researchers investigated the primo vascular system (PVS), a proposed network that may play a role in transport, tissue regeneration, and cell migration. While the PVS has been detected in other rab…
inflammatory cell; placenta; primo vascular system; primo vessel; rabbit.
A
2019
Adhesive capsulitis: MRI correlation with clinical stages and proposal of MRI staging
Amarnath Chellathurai, Komalavalli Subbiah, Atchaya Elangovan,, Sivakumar Kannappan
This study investigated whether magnetic resonance imaging (MRI) findings can reflect the clinical stages of adhesive capsulitis, also known as frozen shoulder. Researchers analyzed MRIs from 74 patients, looking for sp…
Adhesive capsulitis; MRI staging; magnetic resonance imaging; frozen shoulder
A++
2019
Observation using thermography of post-operative reaction after fascial manipulation®
Joanna Fidut-Wrońska, Kamil Chołuj, Justyna Chmiel, Katarzyna Pikto-Pitkiewicz, Piotr Majcher
This study investigated whether Fascial Manipulation® causes a local increase in skin temperature, which is theorized to be part of its mechanism. Researchers used a thermal-imaging camera to measure skin temperature in…
inflammationFascial manipulationthermography
A++
2018
Female hormones: do they influence muscle and tendon protein metabolism?
Mette Hansen
This narrative review examines how female sex hormones, particularly estrogen, influence the metabolism of proteins in muscles and tendons. After menopause, declining hormone levels are associated with accelerated muscl…
ACL anterior cruciate ligament; ER oestrogen receptors; ERT oestrogen replacement therapy; HRT hormone replacement therapy; IGF-I insulin-like growth factor-I; OC oral contraceptive; Collagen; Hormone replacement therapy; Muscle strength; Oestrogen; Sarcopenia.
A
2018
Fascial preadipocytes: another missing piece of the puzzle to understand fibromyalgia?
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Francesca Cavallaro, David Lintonbon
In this review paper, the authors discuss fibromyalgia, a chronic pain condition whose cause remains uncertain. While often linked to changes in the central nervous system, research also points to peripheral nerve damag…
fasciaFibromyalgiapainMyofascialneuropathic pain
1A+
2018
From mechanobiology to developmentally inspired engineering
Donald Ingber
This review article, based on a lecture, explores the field of mechanobiology, which studies the central role of physical forces in development and physiology. The author reviews 40 years of his laboratory's foundationa…
Tensegritymechanicalorgans-on-chipstissue engineering
A
2018
Fascial well-being: Mechanotransduction in manual and movement therapies
Leon Chaitow
This article discusses mechanotransduction, the process by which cells in connective tissue sense and respond to mechanical forces like stretch, compression, and shear. Specialized cells such as fibroblasts communicate…
mechanotransduction
A+++
2018
Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis
Jing Li
This commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…
meta-analysisVitamin CAscorbic acidsepsisSevere sepsis