Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- C2019
Modelling Cell Origami via a Tensegrity Model of the Cytoskeleton in Adherent Cells
Lili Wang, Weiyi ChenResearchers created a computer model to better understand "cell origami," a technique where the natural pulling forces of cells are used to fold tiny structures. This model represents the cell's internal framework, or c…
Tensegritycytoskeletoncell adhesioncell origami - A+++2019
Protein synthesis rates of muscle, tendon, ligament, cartilage, and bone tissue in vivo in humans
Joey S J Smeets, Astrid M H Horstman, Georges F Vles, Pieter J Emans, Joy P B Goessens, Annemie P Gijsen, Janneau M X v…This study measured protein synthesis rates directly in various human knee joint tissues for the first time. Researchers collected samples from muscle, tendon, ligaments, cartilage, and bone during total knee replacemen…
nutritiontissue protein synthesis rateamino acid content in tissues - A2019
Structural Gender Dimorphism and the Biomechanics of the Gluteal Subcutaneous Tissue: Implications for the Pathophysiology of Cellulite
Christina Rudolph, Casey Hladik, Hassan Hamade, Konstantin Frank, Michael S Kaminer, Doris Hexsel, Robert H Gotkin, Nei…This study investigated gender differences in the subcutaneous tissue of the gluteal region to better understand the development of cellulite. Researchers found that men have more and stronger fibrous connections (septa…
celluliteAGEfatty tissuemorpholgygender - A++2019
8 natural supplements to help fight inflammation
Zawn VillinesInflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…
inflammationomega-3curcumin - B2019
Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology
Saba Nayar, Joana Campos, Charlotte G Smith, Valentina Iannizzotto, David H Gardner, Frédéric Mourcin, David Roulois, J…In sites of chronic inflammation or infection, connective tissue cells called fibroblasts can change their behavior. This study shows how a specific group of fibroblasts transforms into a network of so-called "immunofib…
FibroblastsSjögren’s syndromeautoimmunitytertiary lymphoid structures - A++2019
A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
Liane Bolke, Gerrit Schlippe, Joachim Gerß, Werner VossThis randomized, placebo-controlled study investigated the effects of a drinkable nutraceutical containing 2.5g of collagen peptides, vitamins, and minerals on skin health in women aged 35 and older. Over twelve weeks,…
aging; beauty; bioavailability; collagen peptides; corneometry; cutometry; high coverage [HC] collagen complex; wrinkles - A2019
Role of Hyaluronan in Inflammatory Effects on Human Articular Chondrocytes
Mary K Cowman, Claire Shortt, Shivani Arora, Yuhong Fu, Jemma Villavieja, Jai Rathore, Xiayun Huang, Tatini Rakshit, Gy…Some researchers have proposed that fragments of hyaluronan (HA), a key molecule in connective tissue, can trigger inflammation in cartilage. This study investigated that idea in human articular cartilage cells. Researc…
hyaluronan; hyaluronidase; articular cartilage; chondrocytes; inflammation - A2019
Cellular nanoscale stiffness patterns governed by intracellular forces
Nicola Mandriota, Claudia Friedsam, John A Jones-Molina, Kathleen V Tatem, Donald E Ingber, Ozgur SahinCell stiffness is important in many biological processes, but its precise relationship to the forces acting inside the cell has been unclear. In this study, researchers developed a new high-resolution imaging platform t…
Tensegritymechanotransductioncell - cell interaction - A2019
Existence and features of the myodural bridge in Gallus domesticus: indication of its important physiological function
Ya-Ru Dou, Nan Zheng, Jing Gong, Wei Tang, Chukwuemeka Samuel Okoye, Ying Zhang, Yu-Xiao Chen, Yu Zhang, Shi-Yi Pi, Lia…In this anatomical animal study, researchers investigated the existence of the myodural bridge (MDB) in chickens. The MDB is a dense connective tissue that links muscles in the upper neck to the spinal dura mater. The i…
Myodural Bridgecerebrospinal fluid circulationCollagen fiberGallus domesticus - A2019
Suboccipital Myodural Bridges Revisited: Application to Cervicogenic Headaches
KEI KITAMURA, KWANG HO CHO, MASAHITO YAMAMOTO, MICHITAKE ISHII, GEN MURAKAMI, JOSÉ FRANCISCO RODRÍGUEZ-VÁZQUEZ, SHIN-IC…This anatomical study investigated the connective tissue structures, known as myodural bridges, in the suboccipital region of 30 human fetuses. Researchers identified two types of these bridges connecting muscles at the…
fetuses; atlas; cervical; cervical vertebra axis; pachymeninx; elastic fibers; cervicogenic headaches - A2019
The myodural bridge complex defined as a new functional structure
Nan Zheng, Beom Sun Chung, Yi-Lin Li, Tai-Yuan Liu, Lan-Xin Zhang, Yang-Yang Ge, Nan-Xing Wang, Zhi-Hong Zhang, Lin Cai…The myodural bridge is a known connective tissue link between the deep suboccipital muscles and the spinal cord's outermost covering, the dura mater. In this anatomical study, researchers examined its precise structure…
Myodural BridgeThree-dimensional visualization modelP45 plastinated slicesSuboccipital region - A2019
Anterior capsular abnormality: another important MRI finding for the diagnosis of adhesive capsulitis of the shoulder
Jina Park, Yoon-Hee Choi, Jee Won Chai, Seung Woo Cha, Joo Hee Lim, Chris Hyunchul Jo, Dong Hyun KimThis retrospective study investigated whether abnormalities in the shoulder's anterior joint capsule, seen on MRI scans, can help diagnose adhesive capsulitis (frozen shoulder). Researchers compared MRIs from 29 patient…
Anterior capsular abnormalityAdhesive capsulitis of shoulderAnterior capsular thicknessAnterior capsular abnormal hyperintensity