Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 217–228 of 1,131 studies · page 19/95

A+
2020
Role of vitamin K 2 in bone metabolism: a point of view and a short reappraisal of the literature
A Capozzi, G Scambia, S Migliaccio, S Lello
This narrative review examines the role of Vitamin K2 in bone metabolism and its contribution to maintaining skeletal integrity. Vitamin K2 is essential for activating osteocalcin, a key protein that binds calcium to th…
Vitamin K2; bone; fracture; menaquinone; osteoporosis
A++
2020
Is the extent of obstetric anal sphincter injury correlated with the severity of fecal incontinence in the long term?
L Luciano, M. Bouvier, K Baumstarck, V Vitton
This retrospective study investigated the relationship between the extent of obstetric anal sphincter injury and the severity of long-term fecal incontinence (FI). Researchers analyzed data from 250 women with a mean ag…
Fecal incontinence · Obstetrical anal sphincter injury · Endoanal ultrasonography · 3D high-resolution anorectal manometry · Delivery
A++
2020
The potential of cannabidiol in the COVID-19 pandemic
Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Walter Sanseverino, Jie Lu, Chiara Corpetti, Giovanni Sarnelli
This scientific hypothesis explores the potential of cannabidiol (CBD) as a supportive treatment during the COVID-19 pandemic. The authors suggest that CBD may down-regulate the receptors the virus uses for cellular ent…
fibrosisCannabinoidsimmune systemCOVID-19anti-inflammatory
A+++
2020
Cannabis and cannabidiol (CBD) for the treatment of fibromyalgia
Amnon A Berger, Joseph Keefe, Ariel Winnick, Elasaf Gilbert, Jonathan P Eskander, Cyrus Yazdi, Alan D Kaye, Omar Viswan…
This narrative review examines the use of cannabis and cannabidiol (CBD) for treating fibromyalgia, a complex condition that often responds poorly to standard therapies. The authors note that while high-quality randomiz…
CBT; SNRI; SSRI; chronic pain; depression; myalgia.
A+++
2020
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X Wong
This randomized controlled trial investigated how daily resveratrol supplementation affects brain health in postmenopausal women over a 12-month period. Participants took either 75 mg of trans-resveratrol twice daily or…
ageing; cerebrovascular function; cognitive decline; menopause; neurovascular coupling; nutraceutical; phytoestrogen; resveratrol
A
2020
Ageing of the diaphragm muscle
Bruno Bordoni, Bruno Morabito, Marta Simonelli
This narrative review explores how the diaphragm, our main breathing muscle, is affected by aging. Like other muscles, the diaphragm can weaken and lose mass over time, a condition known as sarcopenia. This age-related…
fasciadiaphragmskeletal musclephrenic nervevagus nerve
A++
2020
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
Lijun Wang, Xiuling You, Sutada Lotinun, Lingli Zhang, Nan Wu, Weiguo Zou
This study using mouse models investigates how the protein PIEZO1 acts as a mechanical sensor in the skeleton to regulate bone mass. Researchers found that a deficiency of PIEZO1 in bone-forming cells (osteoblasts) lead…
mechanotransductionpiezobone homeostasis
A
2020
Muscle Cramps
Bruno Bordoni, Kavin Sugumar, Matthew Varacallo
Muscle cramps are involuntary, painful, and localized contractions of a muscle or muscle fibers, often felt as a palpable knot. While common in sports, their exact cause is not fully understood and likely depends on var…
Diagnosiscramp
A+++
2020
Fasting-mimicking diet plus chemotherapy in breast cancer treatment
Claudio Vernieri, Francesca Ligorio, Emma Zattarin, Licia Rivoltini, Filippo de Braud
This clinical trial investigated whether a fasting-mimicking diet (FMD) combined with chemotherapy could improve outcomes for breast cancer patients. The overall results were negative, meaning the study did not find a s…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; breast cancer
B
2020
Sympathetic activation: a potential link between comorbidities and COVID-19
Andrea Porzionato, Aron Emmi, Silvia Barbon, Rafael Boscolo-Berto, Carla Stecco, Elena Stocco, Veronica Macchi, Raffael…
In this perspective article, researchers propose a potential link between common comorbidities and severe COVID-19 outcomes. Conditions like heart disease, hypertension, and diabetes, which are risk factors for severe C…
autonomic nervous system; COVID-19; diabetes; heart failure; hypertension; kidney disease; obesity; SARS-CoV-2; smoking; sympathoactivation
A+++
2020
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
Eduardo Dourado, Margarida Ferro, Catarina Sousa Guerreiro, João Eurico Fonseca
This narrative review explores how dietary patterns can influence the gut microbiota in individuals with rheumatoid arthritis (RA). Research indicates that RA patients often exhibit significant differences in their inte…
Mediterranean diet; gut microbiota; probiotics; rheumatoid arthritis
A+++
2020
Gut Microbiota and Cardiovascular Disease
Marco Witkowski, Taylor L Weeks, Stanley L Hazen
This review explores how the gut microbiota influences cardiovascular health through the production of specific metabolic byproducts. Research suggests that the link is not merely associative; certain bacterial metaboli…
atherosclerosis; cardiovascular diseases; gastrointestinal microbiome; thrombosis; vascular diseases