Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2020
Endocannabinoids release after Osteopathic Manipulative Treatment. A brief review
Andrea Buscemi, Simona Martino, Santi Scirè Campisi, Alessandro Rapisarda, Marinella CocoThis brief review examines how Osteopathic Manipulative Treatment (OMT) may influence the body's endocannabinoid system, which is crucial for pain regulation and emotional well-being. By analyzing existing research, the…
chronic pain; endocannabinoids; hypothalamic-pituitary-adrenal axis; osteopathic manipulative treatment - A+2020
Tissue Micro-channels Formed by Collagen Fibers and their Internal Components: Cellular Evidence of Proposed Meridian Conduits in Vertebrate Skin
Bai Xuebing, Wu Ruizhi, Zhang Yue, Liang Chunhua, Shi Yonghong, Zhang Yingxin, Ding Baitao, Imran Tarique, Yang Ping, C…This study examined fascia from various vertebrate species using microscopy to search for physical structures that might correspond to the meridian conduits described in Traditional Chinese Medicine (TCM). Researchers i…
Collagen fiberTelocyteChinese traditional medicinemeridian conduittissue micro-channel - A++2020
Therapeutic importance of hydrogen sulfide in age-associated neurodegenerative diseases
Rubaiya Tabassum, Na Young Jeong, Junyang JungThis narrative review explores the potential of molecular hydrogen (H2) as a preventive and therapeutic medical gas for various health conditions. H2 acts as a selective antioxidant, specifically targeting the most harm…
3-mercaptopyruvate sulfurtransferase; aging; antioxidant; cystathionine β-synthase; cystathionine γ-lyase; glutathione; hydrogen sulfide; neurodegenerative disease; oxidative stress; reactive oxygen species - A++2020
The Efficacy of Stretching Exercises on Arterial Stiffness in Middle-Aged and Older Adults: A Meta-Analysis of Randomized and Non-Randomized Controlled Trials
Michitaka Kato, Fumi Nihei Green, Kazuki Hotta, Toshiya Tsukamoto, Yasunari Kurita, Akira Kubo, Hisato TakagiThis meta-analysis reviewed eight studies involving 213 middle-aged and older adults to see how stretching affects arterial stiffness. The combined results suggest that regular stretching can significantly reduce arteri…
stretching exercises; arterial stiffness; endothelial function; middle-aged; older adult - A+++2020
Ascorbate as Prophylaxis and Therapy for COVID-19—Update From Shanghai and U.S. Medical Institutions
Richard Z Cheng, Mikhail Kogan, Devra DavisThis 2020 report describes how a medical panel in Shanghai evaluated the use of intravenous (IV) ascorbate, or vitamin C, for patients with severe COVID-19. The panel reviewed existing studies and preliminary data from…
COVID-19public healthglobal healthintravenous ascorbate - A2020
A Novel Role of Ascorbic Acid in Anti-Inflammatory Pathway and ROS Generation in HEMA Treated Dental Pulp Stem Cells
Francesca Diomede, Guya Diletta Marconi, Simone Guarnieri, Michele D’Attilio, Marcos F X B Cavalcanti, Maria A Mariggiò…Components from common dental resins can sometimes cause inflammation and oxidative stress in the cells of the dental pulp. This laboratory study investigated whether ascorbic acid (Vitamin C) could protect human dental…
human dental pulp stem cells; hema; ascorbic acid; nfkb; erk; perk; inflammatory cytokines - A+++2020
Is the VITAMINS RCT indicating potential redundancy between corticosteroids and vitamin C?
Anitra C CarrKnown only by its title, this article appears to be a commentary or analysis of a randomized controlled trial (RCT) known as VITAMINS. The title poses a question about whether there might be a "redundancy," or overlappi…
Vitamin Ccorticosteroidsstress respons - A+++2020
Overview of the possible role of vitamin C in management of COVID-19
Anis Abobaker, Aboubaker Alzwi, Alsalheen Hamed A AlraiedIn this 2020 review, the authors examine the possible role of vitamin C in managing COVID-19. They note that the body's vitamin C levels often drop during an acute infection due to increased metabolic demands. Because v…
Vitamin CCOVID-19SARS-CoV-2Beneficial effectsManagement - A+++2020
Effects of Cesarean Section and Vaginal Delivery on Abdominal Muscles and Fasciae
Chenglei Fan, Diego Guidolin, Serena Ragazzo, Caterina Fede, Carmelo Pirri, Nathaly Gaudreault, Andrea Porzionato, Vero…This study used ultrasound to compare the abdominal muscles and fascia of women who had a C-section, a vaginal delivery, or had never given birth. Researchers found that both types of delivery were associated with chang…
caesarean section; vaginal delivery; fascia; abdominal muscles; pain; ultrasound - A+++2020
Antiviral Mechanisms of Vitamin C: A Short Communication Consensus Report
Michael J Gonzalez, Jorge R Miranda-Massari, Jose R Rodriguez, Victor Marcial-Vega, Miguel J Berdiel, Jorge Duconge, St…This 2020 publication is a consensus report from a large group of authors, summarizing agreed-upon points regarding vitamin C. Based on the title, the report details the various mechanisms by which vitamin C may exert a…
Vitamin CAscorbic acidantiviral effects - A+++2020
Vitamin D insufficiency as a potential culprit in critical COVID-19 patients
Ruhul Munshi, Mohammad H Hussein, Eman A Toraih, Rami M Elshazli, Christina Jardak, Nasrin Sultana, Mohanad R Youssef,…In this systematic review, researchers analyzed data from six studies to explore the association between vitamin D levels and COVID-19 severity. They found that patients with a poor prognosis had significantly lower ser…
meta-analysisCOVID-19SARS-CoV-2vitamin Doutcome - A+2020
Regular Supplementation With Resveratrol Improves Bone Mineral Density in Postmenopausal Women: A Randomized, Placebo-Controlled Trial
Rachel H X Wong, Jay Jay Thaung Zaw, Cory J Xian, Peter R C HoweThis randomized, placebo-controlled trial investigated how daily resveratrol supplementation affects bone health in postmenopausal women. Over 12 months, participants taking 75 mg of resveratrol twice daily showed incre…
AGING; CLINICAL TRIALS; DXA; MENOPAUSE; NUTRITION