Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
- A+2016
Health E!ects of Alkaline Diet and Water, Reduction of Digestive-tract Bacterial Load, and Earthing
Haider Abdul-Lateef MousaThis narrative review discusses how an alkaline diet, alkaline water, reduced digestive-tract bacterial load, and “earthing” might counter chronic low-grade acidosis. The author synthesizes literature suggesting these a…
chronic inflammationearthinghypertensionMetabolic acidosisalkaline diet - A++2016
Fascial hierarchies and the relevance of crossed-helical arrangements of collagen to changes in shape; part II: The proposed effect of blood pressure (Traube-Hering-Mayer) waves on the fascia
Graham ScarrPeriodic changes in blood pressure, known as Traube-Hering-Mayer waves, are linked to respiration and nervous system activity. While complex and not fully understood, they can provide valuable clinical information. This…
Arterial pressure waveform; Collagen; Cranial rhythmic impulse; Fascia; Helix; Interstitial fluid flow; Mayer waves; Myofascia; Traube Hering - B2016
Hyaluronic Acid in Inflammation and Tissue Regeneration
Malgorzata Litwiniuk, Alicja Krejner, Tomasz GrzelaThis review article summarizes the role of hyaluronic acid (HA) in tissue healing. As a main component of the extracellular matrix, HA is a key player in tissue regeneration. Interestingly, its effects depend on its mol…
hyaluronic acid; extracellular matrix; wound healing; Inflammation - A+2016
Comparison of the Hyaluronic Acid Vaginal Cream and Conjugated Estrogen Used in Treatment of Vaginal Atrophy of Menopause Women: A Randomized Controlled Clinical Trial
Azam Jokar, Tayebe Davari, Nasrin Asadi, Fateme Ahmadi, Sedighe ForuhariThis randomized controlled clinical trial compared the effectiveness of hyaluronic acid vaginal cream with conjugated estrogen cream for treating vaginal atrophy in menopausal women. Over an eight-week period, researche…
Atrophic vaginitis; Estrogen; Hyaluronic acid; Menopause - A2016
Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration
Michele M Temple-Wong, Shuwen Ren, Phu Quach, Bradley C Hansen, Albert C Chen, Akihiko Hasegawa, Darryl D D’Lima, Jim K…This study investigated how the lubricant hyaluronan in knee joint fluid changes with age and cartilage wear. Researchers analyzed synovial fluid from human donors aged 23 to 91 without diagnosed osteoarthritis. They fo…
hyaluronanAgingSynovial fluidDegeneration - A++2016
Amelioration of estrogen deficiency-induced obesity by collagen hydrolysate
Tsay-I Chiang, I-Chang Chang, Hsueh-Hui Lee, Kuang Hui Hsieh, Yung-Wei Chiu, Te-Jen Lai, Jer-Yuh Liu, Li-Sung Hsu, Shao…This animal study on rats investigated how collagen hydrolysate supplementation might affect the weight gain often associated with estrogen deficiency, similar to menopause. Researchers found that rats receiving collage…
Collagen; Obesity; estrogen deficiency - 1A+2016
STRETCHING IMPACTS INFLAMMATION RESOLUTION IN CONNECTIVE TISSUE
L Berrueta, I Muskaj, S Olenich, T Butler, G J Badger, R A Colas, M Spite, C N Serhan, H M LangevinIn this animal study, researchers investigated the effect of stretching on acute inflammation in the connective tissue of rats. After inducing local inflammation in the rats' backs, one group was subjected to twice-dail…
Stretching; SPM; Resolvin; Inflammation; Connective tissue - A2016
Fascial Manipulation Associated With Standard Care Compared to Only Standard Postsurgical Care for Total Hip Arthroplasty: A Randomized Controlled Trial
Massimo Busato, Cristian Quagliati, Lara Magri, Alessandra Filippi, Alberto Sanna, Mirco Branchini, Aurelie Marie March…This randomized controlled trial investigated the effects of adding Fascial Manipulation (FM) to standard rehabilitation after total hip replacement surgery. Researchers divided 51 patients into two groups: one received…
Fascial manipulationHip arthroplasty - A2016
Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series
Preeti Raghavan, Ying Lu, Mona Mirchandani, Antonio SteccoThis case series investigated injections of the enzyme hyaluronidase to treat upper limb muscle stiffness in 20 individuals with cerebral injury. The researchers hypothesized that an accumulation of hyaluronan in the mu…
fasciaConnective tissueStrokeHypertoniaspasticity - A2016
Hyaluronan production and molecular weight is enhanced in pathway-engineered strains of lactate dehydrogenase-deficient Lactococcus lactis
Mandeep Kaur, Guhan JayaramanResearchers are exploring ways to use engineered bacteria to produce hyaluronic acid (HA), but the yield and molecular weight have often been limited. Previous work suggested that excessive lactate production might be t…
Hyaluronic acid molecular weightLactococcus lactisLactate dehydrogenase mutantNADþ/NADH ratioHA-precursor concentration ratio - A+++2016
Effects of whole body vibration exercises on bone mineral density of women with postmenopausal osteoporosis without medications: novel findings and literature review
C F Dionello, D Sá-Caputo, H Vfs Pereira, C R Sousa-Gonçalves, A I Maiworm, D S Morel, E Moreira-Marconi, L L Paineiras…This systematic review examines the effects of whole-body vibration (WBV) exercises on bone mineral density in postmenopausal women with osteoporosis who are not taking medication. By analyzing twelve studies, researche…
postmenopausbone densitywhole body vibrationvibration; osteoporosis - A2016
Telocytes in focus
Sandra Maria CretoiuThis is a title-only entry, and its contents have not yet been summarized. The title is 'Telocytes in focus', authored by Sandra Maria Cretoiu and published in 2016. Without an abstract or full text, the specific findin…
telocytes - C2016
Protein—glycosaminoglycan interaction networks: Focus on heparan sulfate
Sylvie Ricard-BlumThis research overview describes a project focused on glycosaminoglycans (GAGs), complex sugars found on the cell surface and in the extracellular matrix. Specifically, it investigates heparan sulfate and how it interac…
extracellular matrixHeparan sulfateInteraction networksInteraction databasesSurface plasmon resonance - A2016
Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase
Sebastian Kalamajski, Dominique Bihan, Arkadiusz Bonna, Kristofer Rubin, Richard W FarndaleFibrosis is characterized by a dense and stiff collagen matrix, formed through a cross-linking process driven by the enzyme lysyl oxidase (LOX). This study investigated the role of another protein, fibromodulin, in this…
fibrosiscollagen cross-linkingfibromodulinlysyl oxidase - A++2016
Can fascia’s characteristics be influenced by manual therapy
Serge GracovetskyThis theoretical essay investigates the fundamental properties of collagen, a key component of fascia. The author explores how manual therapy might relate to the necessity of maintaining collagen's strength under load.…
Collagen; Models; MMP; Water - 1A+2016
Expression of the endocannabinoid receptors in human fascial tissue
Caterina Fede, G Albertin, L Petrelli, M M Sfriso, C Biz, R De Caro, Carla SteccoResearchers investigated whether human fascia contains cannabinoid receptors, which are part of the body's endocannabinoid system. Taking small tissue samples from volunteers during orthopedic surgery, they analyzed the…
fascia; fascial fibroblasts; endocannabinoid; immunostaining - A++2016
Ultra-weak photon emission of hands in aging prediction
Xin Zhao, Eduard van Wijk, Yu Yan, Roeland van Wijk, Huanming Yang, Yan Zhang, Jian WangThis study, for which a full summary is not yet available, appears to investigate the relationship between ultra-weak photon emissions from the hands and the biological aging process. The title suggests researchers expl…
AgingbiophotonsUltra-weak photon emissionModel prediction - 1A+2016
Hormone receptor expression in human fascial tissue
Caterina Fede, G Albertin, L Petrelli, M M Sfriso, C Biz, R De Caro, Carla SteccoAdult women tend to experience more myofascial pain than men, and this study explored a possible hormonal link. Researchers examined fascial tissue from eight female volunteers, looking for receptors for the hormones es…
Fascia; fascial fibroblasts; estrogen; relaxin; immunostaining - A++2016
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study
James P Lugo, Zainulabedin M Saiyed, Nancy E LaneThis randomized, double-blind, placebo-controlled study evaluated the effects of undenatured type II collagen (UC-II) on symptoms of knee osteoarthritis. Over a 180-day period, 191 volunteers received either 40 mg of UC…
osteoarthritisKnee functionT regulatorycellUndenaturedtype II collagen - A++2016
Ultra-weak photon emission in healthy subjects and patients with type 2 diabetes: evidence for a non-invasive diagnostic tool
Meina Yang, Wenyu Ding, Yanli Liu, Hua Fan, Rajendra P Bajpai, Jialei Fu, Jingxiang Pang, Xiaolei Zhao, Jinxiang HanAll living organisms emit extremely faint light, known as ultra-weak photon emission (UPE). This study investigated whether these light emissions differ between healthy individuals and people with type 2 diabetes. Resea…
fasciaphoton emissionbiological systemspathological statesUE - A+++2016
Resveratrol attenuated estrogen-deficient-induced cardiac dysfunction: role of AMPK, SIRT1, and mitochondrial function
Zijun Meng, Hongjiang Jing, Lu Gan, Hua Li, Bingde LuoThis animal study investigated how resveratrol, an antioxidant found in red grapes, affects cardiac function in estrogen-deficient mice. Researchers found that resveratrol supplementation significantly improved heart co…
AMPK; Resveratrol; SIRT1; heart; ischemia; mitochondrion - A+++2016
Efficacy of an orally administered combination of hyaluronic acid, chondroitin sulfate, curcumin and quercetin for the prevention of recurrent urinary tract infections in postmenopausal women
M Torella, F Del Deo, A Grimaldi, S A Iervolino, M Pezzella, C Tammaro, P Gallo, C Rappa, P De Franciscis, N ColacurciThis prospective study evaluated whether an oral supplement containing hyaluronic acid, chondroitin sulfate, curcumin, and quercetin could prevent recurrent urinary tract infections (UTIs) in postmenopausal women. Resea…
Curcumin; Estrogen; Glycosaminoglycans; Quercetin; Urinary tract infections - A2016
The Physical Mechanism for Retinal Discrete Dark Noise: Thermal Activation or Cellular Ultraweak Photon Emission?
Vahid Salari, Felix Scholkmann, Istvan Bokkon, Farhad Shahbazi, Jack TuszynskiThe visual 'static' or 'noise' we perceive in complete darkness has long been a puzzle. The conventional explanation is that random thermal energy causes photoreceptor cells in the retina to fire, but this model doesn't…
Biophotons - A2016
Cystocele and functional anatomy of the pelvic floor: review and update of the various theories
Géry Lamblin, Emmanuel Delorme, Michel Cosson, Chrystèle RubodThis narrative review examines different anatomical theories about how the pelvic floor supports the bladder. The researchers summarize that this support involves a complex interplay of the pubocervical fascia, endopelv…
Pelvic floor . Cystocele . Connective tissue . Anatomy . Endopelvic fascia . Pelvic mobility - A2016
Endogenous spontaneous ultraweek photon emission in the formation of eye-specific retinogeniculate projections before birth
István Bókkon, Felix Scholkmann, Vahid Salari, Noémi Császár, Gábor KapócsIt has long been a puzzle how the intricate nerve connections between the eye and brain form so accurately before birth, without any visual input. This theoretical paper proposes a novel explanation for this phenomenon.…
discrete retinal noise; intrinsically photosensitive retinal ganglion cells; retinogeniculate pathways; spontaneous ultraweak photon emission - A++2016
Myofascial triggerpoint release (MTR) for treating chronic shoulder pain: A novel approach
Christopher-Marc Gordon, Frank Andrasik, Robert Schleip, Niels Birbaumer, Massimiliano ReaThis study evaluated a specific manual therapy, myofascial trigger point release (MTR), for chronic shoulder pain. Twenty-three participants received four 10-minute sessions over two weeks, applied only to their more pa…
Algometer; Chronic shoulder pain; Myofascial triggerpoint release; Myometer; Quality of life; Stress. - A+++2016
Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells
Brett A Morris, Brian Burkel, Suzanne M Ponik, Jing Fan, John S Condeelis, Julio A Aguirre-Ghiso, James Castracane, Joh…This study used a 3D in vitro model to investigate how the density of the collagen matrix influences the metabolism of breast cancer cells. The researchers observed that a high-density extracellular matrix drives a meta…
Breast cancer; Collagen; Matrix density; Metabolism - B2016
Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs
Agata Jabłońska-Trypuć, Marzena Matejczyk, Stanisław RosochackiThis review article describes matrix metalloproteinases (MMPs), the primary enzymes responsible for breaking down collagen in the extracellular matrix. This breakdown process is normal and necessary for tissue remodelin…
cancercollagenAngiogenesisapoptosismetalloproteinase - B2016
Internal strain drives spontaneous periodic buckling in collagen and regulates remodeling
Andrew Dittmore, Jonathan Silver, Susanta K Sarkar, Barry Marmer, Gregory I Goldberg, Keir C NeumanThis study investigated how collagen, a key structural protein, is remodeled. Researchers observed that the enzymes responsible for breaking down collagen, called MMPs, bind to specific, vulnerable spots that appear at…
mechanosensingCollagenasematrix metalloproteinasesingle moleculepattern formation - A++2016
Effects of matrix rhythm therapy on primary lymphedema: a case report
Ayse Neriman Narin, Ayse Zengin Alpozgen, Hilal Denizoglu KulliThis case report investigated the effects of Matrix Rhythm Therapy on a 36-year-old woman with primary lymphedema in her left leg. She received 20 sessions of the therapy over four weeks, applied to the affected leg, sp…
Matrix Rhythm TherapyLower limbPrimary lymphedema - A+2016
Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review
David G Behm, Anthony J Blazevich, Anthony D Kay, Malachy McHughThis systematic review examines how different types of stretching (static, dynamic, and PNF) affect performance, range of motion (ROM), and injury risk in healthy individuals. The findings suggest that static stretching…
ballistic stretch; dynamic stretch; facilitation neuromusculaire proprioceptive; flexibility; flexibilité; proprioceptive neuromuscular facilitation; static stretch; warm-up - A2016
A five year follow-up of women with obstetric anal sphincter rupture at their first delivery
Sidsel Linneberg, Stine Leenskjold, Karin GlavindThis study followed 82 women for five years after they experienced an obstetric anal sphincter rupture (OASR) during their first delivery. Researchers investigated long-term outcomes like incontinence and sexual functio…
urinary incontinenceanal incontinenceObstetric anal sphincter ruptureSexual dysfunctionValidated questionnaires - A++2016
Estrogen and Pelvic Organ Prolapse
Ling Zhou, Anna Junjie Shangguan, Stacy Ann Kujawa, Katarzyna Bochenska, Lanmei Zhang, Serdar E Bulun, Hong ZhaoThis narrative review explores the relationship between estrogen and pelvic organ prolapse (POP), a condition where pelvic organs descend from their normal positions. Research suggests that low estrogen levels, particul…
Pelvic organ prolapse; Estrogen; Estrogen receptor; Collagen; Matrix metalloproteinases - A+2016
The relationship between pelvic alignment and dysmenorrhea
Moon-Jeong Kim, Il-Hun Baek, Bong-Oh GooThis study investigated the relationship between pelvic alignment and dysmenorrhea (menstrual pain). Researchers compared 102 women, divided into a group with menstrual pain and a group without, using 4D imaging to meas…
AlignmentDysmenorrheaPelvic torsion - A+2016
Piezo2 is the principal mechanotransduction channel for proprioception
Seung-Hyun Woo, Viktor Lukacs, Joriene C de Nooij, Dasha Zaytseva, Connor R Criddle, Allain Francisco, Thomas M Jessell…Proprioception is the sense of where our body parts are in space. In this animal study, researchers investigated the molecular sensor responsible for this ability in mice. They found that an ion channel called Piezo2 wa…
proprioceptionmuscle spindlespiezomechanotranductiiongolgi tendon organ - B2016
Limited mechanical effects of intermuscular myofascial connections within the intact rat anterior crural compartment
Chris Tijs, Jaap H van Dieën, Huub MaasIn this animal study, researchers investigated the connective tissue links between two lower leg muscles in rats, the tibialis anterior and extensor digitorum longus. The goal was to see if these connections significant…
Tibialis anteriorExtensor digitorum longus3D kineticsCo-activationMechanical interaction - A++2016
Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity
Denise Morais da Fonseca, Timothy W Hand, Seong-Ji Han, Michael Y Gerner, Arielle Glatman Zaretsky, Allyson L Byrd, Oli…A single acute infection can have long-term consequences for tissue-specific immunity, even after the pathogen is cleared. This study found that following a gut infection with Yersinia pseudotuberculosis, sustained infl…
Gut microbiome / Immunity - C2016
Differential displacement of soft tissue layers from manual therapy loading
Shawn Engell, John J Triano, James R Fox, Helene M Langevin, Elisa E KonofagouTo better understand how manual therapy affects the body, researchers investigated how different layers of soft tissue in the back respond to pressure. They applied a standard preparatory force to the thoracic paraspina…
Spinal manipulationBiomechanicsElastographyCumulative displacementShear displacement - A+++2016
Nutraceutical supplement in the management of tendinopathies: a systematic review
Federico Fusini, Salvatore Bisicchia, Carlo Bottegoni, Antonio Gigante, Fabio Zanchini, Alberto BusilacchiThis systematic review examines the effects of various nutraceuticals, such as glucosamine, chondroitin, vitamin C, and curcumin, in managing tendon disorders. While preclinical research on cells and animals shows promi…
arginine alpha-keto-glutarate; ascorbate; boswellic acid; curcumin; oral supplement; tendon disorder - B2016
Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology
Helene M Langevin, Patricia Keely, Jun Mao, Lisa M Hodge, Robert Schleip, Gary Deng, Boris Hinz, Melody A Swartz, Bever…Many cancer patients use complementary therapies like massage, acupuncture, and yoga to improve their quality of life. This review article suggests these treatments may have further benefits by affecting the body's conn…
fasciaextracellular matrixcancerConnective tissue - A+++2016
Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation
William R Thompson, Alexander Scott, M Terry Loghmani, Samuel R Ward, Stuart J WardenThis perspective article explores the field of mechanobiology and how physical therapists use mechanical forces to promote tissue healing. It explains that cells in our muscles, bones, and tendons respond to physical st…
RehabilitationTherapymechantransduction - A2016
Telocytes and Their Extracellular Vesicles—Evidence and Hypotheses
Dragos Cretoiu, Jiahong Xu, Junjie Xiao, Sanda M CretoiuThis narrative review discusses telocytes, a relatively new type of interstitial cell found throughout the body's connective tissues. These cells are characterized by long projections and are involved in communication b…
telocytes; telopodes; extracellular vesicles; exosomes; ectosomes - A+++2016
Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?
Tarique Hussain, Bie Tan, Yulong Yin, Francois Blachier, Myrlene C B Tossou, Najma RahuThis narrative review explores the link between oxidative stress and inflammation, focusing on how plant-derived polyphenols may mitigate these processes. Oxidative stress occurs when reactive oxygen species overwhelm t…
inflammationOxidative stresspolyphenols - C2016
Functional in vitro tension measurements of fascial tissue – a novel modified superfusion approach
Robert Schleip, Werner Klingler, S Wearing, I Naylor, M Zuegel, K HoppeIn this laboratory study on rat tissue, researchers compared two techniques for measuring tension changes in fascia. The traditional method involves immersing the tissue in a fluid bath, but the team also tested a modif…
fasciaOrgan BathMechanographic RegistrationSuperfusionImmersionmized Mice - A+++2016
Vitamin C and Heart Health: A Review Based on Findings from Epidemiologic Studies
Melissa A Moser, Ock K ChunThis review examines the relationship between vitamin C and heart health by analyzing data from epidemiological studies and clinical trials. Research suggests that vitamin C may protect blood vessels by preventing the o…
cardiovascular disease; clinical trials; meta-analyses; observational cohort studies; vitamin C. - B2016
Stretch-induced network reconfiguration of collagen fibres in the human facet capsular ligament
Sijia Zhang, Danielle S Bassett, Beth A WinkelsteinThe facet capsular ligament in the neck is a common source of chronic pain, often resulting from excessive stretching. This study investigated how the collagen fibers within this ligament reorganize when it is stretched…
collagenfibre realignmentfacet capsular ligamentcommunity detectiontime-dependent network - A++2016
Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome
Ludovic Giloteaux, Julia K. Goodrich, William A. Walters, Susan M. Levine, Ruth E. Ley, Maureen R. HansonResearchers investigated the gut microbiome and blood markers of inflammation in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Compared to healthy controls, individuals with ME/CFS had reduced…
inflammationChronic fatigue syndromeMyalgic encephalomyelitisLipopolysaccharidesMicrobiome - A2016
The tongue after whiplash: case report and osteopathic treatment
Bruno Bordoni, Fabiola Marelli, Bruno MorabitoThis case report describes a 30-year-old man who experienced neck pain during swallowing and had a reduced ability to open his mouth following a whiplash injury. He was treated with osteopathic manual techniques directe…
fasciafascial releasetongueindirect osteopathic techniques - A+2016
Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertility
Michele Gomes Da Broi, Paula Andrea NavarroIn this review article, the authors explore the connection between mild endometriosis and infertility. Although the link is known, the exact mechanisms are not fully understood. The researchers suggest that poor oocyte…
Early endometriosis . Infertility . Oocyte quality . Oxidative stress . Follicular microenvironment - A+++2016
Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model
James H Bishop, James R Fox, Rhonda Maple, Caitlin Loretan, Gary J Badger, Sharon M Henry, Margaret A Vizzard, Helene M…This animal study used pigs to investigate how back fascia responds to injury and restricted movement. Researchers created a small injury in the thoracolumbar fascia and also limited movement in some of the pigs for eig…
chronic Low Back Painshear strainimmobilizationfascia mobilitythoracolumbar fascia thickness - A+++2016
A long-distance fluid transport pathway within fibrous connective tissues in patients with ankle edema
Hongyi Li, Chongqing Yang, Kuiyuan Lu, Liyang Zhang, Jiefu Yang, Fang Wang, Dongge Liu, Di Cui, Mingjun Sun, Jianxin Pa…This anatomical study investigated how fluid might drain from swollen ankles. Researchers injected a fluorescent dye into the skin of four lower legs scheduled for amputation to trace fluid movement. They observed that…
interstitial fluidConnective tissuesvascular circulations - A2016
Restoration of Full Shoulder Range of Motion After Application of the Fascial Distortion Model
Joshua D Boucher, Jose FigueroaThis case report describes a 28-year-old man with chronic shoulder pain and severely limited movement, 18 months after an injury. His condition, similar to a frozen shoulder, involved significant pain and an inability t…
frozen shoulderfascial distortion modelrange of motion - A2016
Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways
Pu-Rong Chiu, Yu-Chen Hu, Tzu-Ching Huang, Bau-Shan Hsieh, Jou-Pei Yeh, Hsiao-Ling Cheng, Li-Wen Huang, Kee-Lung ChangIn this study using rat and cell models, researchers investigated if vitamin C could protect cartilage cells against osteoarthritis-like damage. The results showed that vitamin C reduced oxidative stress, inflammation,…
chondrocyte; interleukin; matrix metalloproteinase; osteoarthritis; vitamin C - A+++2016
Fascial Manipulation® for chronic aspecific low back pain: a single blinded randomized controlledtrial.
Mirco Branchini, Francesca Lopopolo, Ernesto Andreoli, Ivano Loreti, Aurélie M Marchand, Antonio SteccoThis randomized controlled trial compared Fascial Manipulation® combined with standard physiotherapy to physiotherapy alone for patients with chronic non-specific low back pain. The group receiving Fascial Manipulation®…
hyaluronanBack PainFascial manipulation - A2016
New evidence of a dynamic fascial maintenance and self-repair process
Leon ChaitowThis 2016 publication by Leon Chaitow has not yet been summarized in detail. Based on its title, the article appears to present new findings that highlight the dynamic processes of fascial maintenance and self-repair. W…
Myofascial self repair - A++2016
Whole-Body and Local Muscle Vibration Immediately Improve Quadriceps Function in Individuals With Anterior Cruciate Ligament Reconstruction
Derek N Pamukoff, Brian Pietrosimone, Michael D Lewek, Eric D Ryan, Paul S Weinhold, Dustin R Lee, J Troy BlackburnThis randomized crossover trial investigated the immediate effects of vibration on quadriceps function in individuals with a prior anterior cruciate ligament (ACL) reconstruction. Twenty participants performed isometric…
Musclevibrationsligament injury - A+++2016
Clinical applications of vibration therapy in orthopaedic practice
Simone Cerciello, Silvio Rossi, Enrico Vison, Katia Corona, Francesco OlivaThis literature review examines the use of vibration therapy in orthopedic practice. Researchers analyzed 71 studies to understand its effects on bone, muscles, and tendons. The review notes that inconsistencies in appl…
RehabilitationAthletesOsteoporosisphysical therapy modalitieselectric stimulation therapy - A+++2016
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
In Young Choi, Laura Piccio, Patra Childress, Bryan Bollman, Arko Ghosh, Sebastian Brandhorst, Jorge Suarez, Andreas Mi…This study investigates how a periodic fasting-mimicking diet (FMD) affects symptoms of multiple sclerosis (MS) using mouse models and preliminary human trials. In animal models, the diet reduced inflammation and promot…
Fasting-mimicking diet; Intermittent fasting; Time-restricted eating; autoimmunity; multiple sclerosis - A++2016
The effect of an active vibration stimulus according to different shoulder joint angles on functional reach and stability of the shoulder joint
Eun-Kyung Kim, Seong-Gil KimThis study investigated how active vibration exercise with a Flexi-Bar at different shoulder angles affected shoulder joint function and stability in 30 healthy male students. Participants were divided into three groups…
Active vibration stimulusFlexi-BarShoulder joint angle - A2015
Understanding Fibroblasts in Order to Comprehend the Osteopathic Treatment of the Fascia
Bruno Bordoni, Emiliano ZanierIn this review paper, the authors argue that understanding fibroblasts is essential for comprehending and applying osteopathic treatment of the fascia. As the foundational cells of connective tissue, fibroblasts have ma…
fasciafibroblastosteopathy