Ultra-weak photon emission of hands in aging prediction
Xin Zhao, Eduard van Wijk, Yu Yan, Roeland van Wijk, Huanming Yang, Yan Zhang, Jian Wang
This study explored using faint light emissions from hands as a potential, non-invasive predictor of biological age.
Aging has been one of the several topics intensely investigated during recent decades. More scientists have been scrutinizing mechanisms behind the human aging process. Ultra-weak photon emission is known as one type of spontaneous photon emission that can be detected with a highly sensitive single photon counting photomultiplier tube (PMT) from the surface of human bodies. It may reflect the body's oxidative damage. Our aim was to examine whether ultra-weak photon emission from a human hand is able to predict one's chronological age. Sixty subjects were recruited and grouped by age. We examined four areas of each hand: palm side of fingers, palm side of hand, dorsum side of fingers, and dorsum side of hand. Left and right hand were measured synchronously with two independent PMTs. Mean strength and Fano factor values of photon counts were utilized to compare the UPE patterns of males and females of different age groups. Subsequently, we utilized UPE data from the most sensitive PMT to develop an age prediction model. We randomly picked 49 subjects to construct the model, whereas the remaining 11 subjects were utilized for validation. The results demonstrated that the model was a good regression compared to the observed values (Pearson's r=0.6, adjusted R square=0.4, p=9.4E-7, accuracy=49/60). Further analysis revealed that the average difference between the chronological age and predicted age was only 7.6±0.8years. It was concluded that this fast and non-invasive photon technology is sufficiently promising to be developed for the estimation of biological aging.
The episode was first published on the Swedish podcast Fasciaguiden on June 4, 2025. In this unique episode, we meet Professor Gerald Pollack — one of the world’s most influential…
The episode was first published on the Swedish podcast Fasciaguiden on May 26, 2025. In this episode, we meet the French surgeon Jean-Claude Guimberteau, who has spent more than 3…