Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2021
Reconnecting the Brain with the Rest of the Body in Musculoskeletal Pain Research
Helene M LangevinIn this commentary, the author argues that musculoskeletal pain research is often siloed into separate specialties like neuroscience, physical therapy, orthopedics, and rheumatology. This separation creates gaps in know…
Musculoskeletal pain; chronic pain; muscle; connective tissue; mind and body practices - A+++2021
Nutrition Provides the Essential Foundation for Optimizing Mental Health
Julia J Rucklidge, Jeanette M Johnstone, Bonnie J KaplanThis review article explores the critical link between nutrition and mental health, written to guide psychologists in their clinical practice. The authors outline how a whole-foods diet supports brain function through v…
Vitamins; minerals; nutrition; nutrients; treatment; mental health - A+++2021
Psychological and biological resilience modulates the effects of stress on epigenetic aging
Zachary M Harvanek, Nia Fogelman, Ke Xu, Rajita SinhaChronic stress is linked to negative health outcomes, and this study explored its connection to accelerated biological aging. Researchers evaluated 444 adults, measuring their cumulative stress, biological age using an…
AgingStresspsychological morbidityanxityepigenetic - A+++2021
Cannabinoids in Breast Cancer: Differential Susceptibility According to Subtype
Cristina Ferreira Almeida, Natércia Teixeira, Georgina Correia-da-Silva, Cristina AmaralThis narrative review explores how different subtypes of breast cancer respond to cannabinoids like THC and CBD. Research suggests that estrogen receptor-negative cells may be more susceptible to these compounds than ho…
Cannabis sativa; anandamide; breast cancer; cannabidiol; cannabidivarin; cannabigerol; cannabinoids; cannabinol; Δ9-tetrahydrocannabinol - A++2021
Decoding the silent walk of COVID-19: Halting its spread using old bullets
Mukesh Kumar, Jitender Madan, Rupinder Kaur Sodhi, Shashi Bala Singh, Anju KatyalThis 2021 review article explores the strategy of using existing drugs to combat the rapidly spreading COVID-19 virus. The authors describe how SARS-CoV-2 affects multiple organ systems, creating a significant therapeut…
Chloroquine; Heparin; Noscapine; Remedesivir; Severe acute respiratory syndrome (SARS-CoV2); Vitamin C. - A+2021
Hyaluronic Acid in Postmenopause Vaginal Atrophy: A Systematic Review
Carlos Campagnaro M Dos Santos, Maria Laura R Uggioni, Tamy Colonetti, Laura Colonetti, Antonio José Grande, Maria Inês…This systematic review evaluated the effectiveness of hyaluronic acid as a treatment for vaginal atrophy in postmenopausal women. By analyzing five primary studies, researchers found that hyaluronic acid appears to offe…
Hyaluronic Acid; Postmenopause; Systematic Review; Vaginal Atrophy - A+2021
Vascular Stiffness in Aging and Disease
Stephen F Vatner, Jie Zhang, Christina Vyzas, Kalee Mishra, Robert M Graham, Dorothy E VatnerThis narrative review examines how vascular stiffness, particularly in the aorta, increases with age and contributes to various cardiovascular diseases. Research suggests that stiffness often progresses more significant…
aging; aortic stiffness; cardiovascular diseases; human; non-human primate - A++2021
Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease
Vyshnavy Balendra, Sandeep Kumar SinghThis narrative review explores how the combination of astaxanthin and the enzyme superoxide dismutase (SOD) may help protect the brain in Alzheimer's disease. Oxidative stress is a key factor in the disease's progressio…
Alzheimer's disease; astaxanthin; neurodegeneration; nutraceuticals; oxidative stress; superoxide dismutase (SOD) - A++2021
Is "Delayed Onset Muscle Soreness" a False Friend? The Potential Implication of the Fascial Connective Tissue in Post-Exercise Discomfort
Jan Wilke, Michael BehringerThis narrative review explores the theory that delayed onset muscle soreness (DOMS) may originate in the connective tissue (fascia) rather than the muscle fibers themselves. While traditional explanations like lactic ac…
DOMS; athletes; eccentric exercise; fascia; pain. - A++2021
Temporomandibular Myofascial Pain Syndrome-Aetiology and Biopsychosocial Modulation. A Narrative Review
Paulina Golanska, Klara Saczuk, Monika Domarecka, Joanna Kuć, Monika Lukomska-SzymanskaThis case report examined the effectiveness of Global Postural Reeducation (GPR) in treating a 23-year-old woman with temporomandibular disorder (TMD) and postural imbalances. By addressing muscle chains and spinal alig…
biopsychosocial profile modulation; bruxism; limbic system; stress; temporomandibular myofascial pain syndrome - A+++2021
The Molecular Targets of Cannabinoids in the Treatment of Cancer and Inflammation
Alenabi Aylar, Malekinejad HassanThis narrative review examines how cannabinoids influence inflammation and cancer by interacting with the body's endocannabinoid system. The researchers describe how endogenous, plant-derived, and synthetic compounds ta…
Cannabinoids; anti-proliferative effects; apoptosis; cancer; cell proliferation; inflammation - A2021
The Effects of Cannabis on Female Reproductive Health Across the Life Course
Daniel J Corsi, Malia S Q Murphy, Jocelynn CookThis narrative review examines how cannabis affects female reproductive health throughout life, from fertility to menopause. While endocannabinoid receptors are present in the reproductive tract, human research remains…
breastfeeding; cannabis; fertility; marijuana; menopause; pregnancy.