Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2011
Dynamic fascial release and the role of mechanical/vibrational assist devices in manual therapies
Zachary ComeauxThis review article explores the use of mechanical vibration devices in manual therapy. The author examines several such tools, including percussion vibrators, vibrational platforms, and deep tissue oscillation. The art…
fasciaConnective tissuevibrationpercussion vibrationtonic vibratory reflex - C2011
Fasciae anatomy
Carla Stecco, Fabrice DuparcThis entry represents a 2011 publication titled "Fasciae anatomy" by Carla Stecco and Fabrice Duparc. As only the title is available, a detailed summary of its contents, such as its specific focus on fascial layers or c…
fasciaAnatomyfasciae - A2011
The extracellular matrix: an active or passive player in fibrosis?
T N Wight, S Potter-PerigoFibrosis, the excessive buildup of scar tissue, can be understood as a wound healing process that has gone awry. Normally, specialized cells called myofibroblasts help repair tissue and then disappear, but in fibrosis,…
fasciaprovisional extracellular matrixmyofibroblatcollagenhyaluronan proteoglycans - B2011
Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
Yuejuan Li, Dianhua Jiang, Jiurong Liang, Eric B Meltzer, Alice Gray, Riu Miura, Lise Wogensen, Yu Yamaguchi, Paul W No…This study investigated the mechanisms behind severe lung fibrosis, a condition where excessive connective tissue builds up in the lungs. Using a mouse model, researchers found that fibroblasts, a type of connective tis…
hyaluronanCD44fibrosis - A+2011
Diet-induced metabolic acidosis
María M Adeva, Gema SoutoThe typical Western diet, high in animal products and low in fruits and vegetables, can lead to a state of chronic, low-grade metabolic acidosis. This means the body becomes slightly more acidic, a situation that can wo…
Metabolic acidosisAmmonium ionsCitrateInsulin resistance - A2011
Correlations Between Fasciology and Yin Yang Doctrine
Hui Tao, Mei-Chun Yu, Hui-Ying Yang, Rong-Mei Qu, Chun Yang, Xin Zhou, Yu Bai, Jing-Peng Wu, Jun Wang, Ou Sha, Lin YuanThis theoretical paper explores correlations between "fasciology," a model based on 3D reconstruction of connective tissue, and the traditional Chinese doctrine of yin and yang. According to fasciology, the body can be…
fasciafasciologyfascial anatomytwo-system theoryyin yang doctrine - A++2011
Optimizing an Intermittent Stretch Paradigm Using ERK1/2 Phosphorylation Results in Increased Collagen Synthesis in Engineered Ligaments
Jennifer Z Paxton, Paul Hagerty, Jonathan J Andrick, Keith BaarThis study on engineered ligaments explored how different stretching patterns affect tissue development. Researchers used a bioreactor to apply cyclic stretch, measuring cellular responses by tracking a key protein call…
collagen synthesisERK 1/2 phosphorylationintermittent stretch - A2011
Assessing the influence of FDM to the postoperative healing processes in distal fracture of the radius
Tomasz TesznerResearchers investigated if the Fascial Distortion Model (FDM) could improve recovery following surgery for a common wrist fracture. In this study, 65 patients were divided into two groups; one received standard rehabil…
fasciaManual Therapyfasciaefascial distortion modelreductionism - A++2011
Review of Evidence Suggesting That the Fascia Network Could Be the Anatomical Basis for Acupoints and Meridians in the Human Body
Yu Bai, Jun Wang, Jin-Peng Wu, Jing-Xing Dai, Ou Sha, David Tai Wai Yew, Lin Yuan, Qiu-Ni LiangThis narrative review explores the idea that the body's fascia network could be the physical structure behind traditional Chinese medicine's (TCM) meridians and acupoints. The authors examine anatomical, physiological,…
fasciaacupunctureacupoints - B2011
Fascia redefined: anatomical features and technical relevance in fascial flap surgery
Carla Stecco, Cesare Tiengo, Antonio Stecco, Andrea Porzionato, Veronica Macchi, Robert Stern, Raffaele De CaroFascia has traditionally been seen as a passive wrapping, but this review redefines it as a dynamic tissue with its own complex blood supply and innervation. The authors detail the specific characteristics of different…
hyaluronanfasciaConnective tissueaponeurosisFlaps - A2011
Fibroblast cytoskeletal remodeling contributes to connective tissue tension
H M Langevin, N A Bouffard, J R Fox, B M Palmer, J Wu, J C Iatridis, W D Barnes, G J Badger, A K HoweThe mechanical properties of connective tissue, such as its elasticity and resistance, have traditionally been attributed to its non-cellular matrix. This study investigated the role of fibroblasts, the cells residing w…
fasciaConnective tissuefibroblastcytoskeletal remodeling - A2011
Hyaluronan: From Extracellular Glue to Pericellular Cue
B P TooleHyaluronan is traditionally seen as a biological 'goo' that lubricates joints and holds connective tissues together. This review describes how hyaluronan also functions as an important signaling molecule, or cue, in the…
hyaluronanfasciasignal transductioncancer
