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59 results for "extracellular matrix"

Research

30

2021
Title match
Cell-to-Cell Communication by Host-Released Extracellular Vesicles in the Gut: Implications in Health and Disease
Natalia Diaz-Garrido, Cecilia Cordero, Yenifer Olivo-Martinez, Josefa Badia, Laura Baldomà
This narrative review explores how small sacs called extracellular vesicles (EVs) act as messengers between cells in the gastrointestinal tract. These vesicles transport proteins, lipids, and genetic material that influ…
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2021
Title match
Gut Microbiota Extracellular Vesicles as Signaling Molecules Mediating Host-Microbiota Communications
Salma Sultan, Walid Mottawea, JuDong Yeo, Riadh Hammami
This review article discusses how small membrane-bound sacs called microbiota-released extracellular vesicles (MEVs) act as messengers between the gut microbiome and the host body. These vesicles carry a variety of biol…
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2020
Title match
Extracellular Vesicles Released From Articular Chondrocytes Play a Major Role in Cell-Cell Communication
Xiaoming Liu, Claire Shortt, Fenglin Zhang, Mariah Q Bater, Mary K Cowman, Thorsten Kirsch
This narrative review examines the role of extracellular vesicles (EVs) as crucial mediators in cell-to-cell communication. EVs are small, lipid-enclosed particles that transport proteins, lipids, and genetic material t…
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2019
Title match
Stiffness and echogenicity: Development of a stiffness-echogenicity matrix for clinical problem solving
Antonio Stecco, Carmelo Pirri, Raffaele De Caro, Preeti Raghavan
Assessing soft tissue stiffness is important for many neuromusculoskeletal conditions, but can be challenging. While ultrasound can measure a tissue's echogenicity (how it reflects sound waves), this is not directly pro…
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2021
Title match
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration
Bingjin Wang, Wencan Ke, Kun Wang, Gaocai Li, Liang Ma, Saideng Lu, Qian Xiang, Zhiwei Liao, Rongjin Luo, Yu Song, Wenbin Hua, Xinghuo Wu, Yukun Zhang, Xianlin…
This study investigates how the mechanical environment of the intervertebral disc influences cellular health during disc degeneration. Researchers found that as the central part of the disc (nucleus pulposus) becomes st…
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2019
Title match
Role of matrix metalloproteinases 2 and 9 in the development of frozen shoulder: human data and experimental analysis in a rat contracture model
Chul-Hyun Cho, Yun-Mee Lho, Ilseon Hwang, Du Hwan Kim
This study investigated the biological processes behind frozen shoulder, a condition characterized by pain and stiffness. Researchers analyzed joint capsule tissue from both patients with frozen shoulder and from a rat…
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2023
Topic match
A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)
Carmelo Pirri, Brasilina Caroccia, Andrea Angelini, Maria Piazza, Lucia Petrelli, Ilaria Caputo, Chiara Montemurro, Pietro Ruggieri, Raffaele De Caro, Carla St…
This study investigated the role of Yes-associated protein (YAP) in the mechanobiology of deep fascia, specifically the thoracolumbar fascia. Researchers analyzed tissue samples from patients and found that YAP acts as…
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2022
Topic match
The Effects of Aging on the Intramuscular Connective Tissue
Caterina Fede, Chenglei Fan, Carmelo Pirri, Lucia Petrelli, Carlo Biz, Andrea Porzionato, Veronica Macchi, Raffaele De Caro, Carla Stecco
This study investigated how intramuscular connective tissue changes with age in both humans and mice. Researchers found that the amount of stiff collagen (Type I) increases significantly with age, while levels of hyalur…
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