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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
Showing 481–540 of 736 studies · page 9/13Since 2015
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  1. B
    2018

    The different distribution of enzymatic collagen cross-links found in adult and children bone result in different mechanical behavior of collagen

    B Depalle, A G Duarte, I A K Fiedler, L Pujo-Menjouet, M J Buehler, J-P Berteau

    This computational study explored how molecular bonds called collagen cross-links affect bone mechanics differently in children and adults. Using models based on real bone samples, researchers simulated how collagen fib…

    Cross-linksChildren boneMolecular modelingBiomechanical properties
  2. 1A+
    2018

    Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model

    L Berrueta, J Bergholz, D Munoz, I Muskaj, G J Badger, A Shukla, H J Kim, J J Zhao, H M Langevin

    In this mouse study, researchers investigated the effect of daily stretching on breast cancer tumors. Mice with implanted tumor cells were divided into two groups, with one group receiving gentle stretching for 10 minut…

    StretchingTumor growthBreast cancer
  3. A
    2018

    A review of the impact of pregnancy and childbirth on pelvic floor function as assessed by objective measurement techniques

    Hans Van Geelen, Donald Ostergard, Peter Sand

    This narrative review examines how pregnancy and childbirth affect the pelvic floor, based on studies using objective measurement tools like ultrasound and MRI. The authors found that pregnancy, particularly the first,…

    Pregnancy . Childbirth . Vaginal delivery . Cesarean delivery . Pelvic floor function . Objective measurement techniques
  4. 1A+
    2018

    Effect of Stretching on Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model

    H M Langevin, J Bishop, R Maple, G J Badger, J R Fox

    In this animal study on pigs, researchers investigated the effect of stretching on the thoracolumbar fascia after injury and movement restriction. An injury combined with restricted movement led to reduced fascial mobil…

    fasciaConnective tissueStretchingManual TherapyMovement Therapy
  5. A
    2018

    Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C

    Shinjini Ganguly, Ayan Chandra, Indu B Chatterjee

    In this animal study, researchers investigated how cigarette smoke might cause invasive cancer of the renal pelvis and if vitamin C could offer protection. They found that when guinea pigs were exposed to cigarette smok…

    Invasive cancer of the renal pelvis Cigarette smoke Vitamin C Oxidative damage Persistent EGFR signaling Cell cycle deregulation
  6. A
    2018

    Therapeutic potentials of superoxide dismutase

    H Younus

    This narrative review explores the therapeutic potential of superoxide dismutases (SODs), a group of enzymes that serve as a crucial antioxidant defense against oxidative stress in the body. The author discusses the rol…

    Oxidative stresssuperoxide dismutasetherapeutic effects
  7. C
    2017

    Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin

    Patricia Paracuellos, Sebastian Kalamajski, Arkadiusz Bonnac, Dominique Bihanc, Richard W. Farndale, Erhard Hohenester

    Fibromodulin and chondroadherin are small proteins that help organize the extracellular matrix. This study examined their 3D structure and how they interact with collagen. Researchers found that while their overall shap…

    Cell signalingfibromodulinchondroadherinextra cellular matrix
  8. A
    2017

    The myodural bridge existing in the Nephocaena phocaenoides

    Pei Liu, Chan Li, Nan Zheng, Qiang Xu, Sheng-Bo Yu, Hong-Jin Sui

    The myodural bridge is a connection between a small neck muscle and the spinal cord's outer covering (the dura mater) previously identified in humans. In this anatomical animal study, researchers investigated whether a…

    dura materMyodural Bridge
  9. A+
    2017

    Theoretical study of aerobic vitamin C loss kinetics during commercial heat preservation and storage

    Micha Peleg

    This theoretical study presents a mathematical model to describe how vitamin C is lost in food during commercial heat processing and storage. The model accounts for the degradation of two forms of the vitamin, ascorbic…

    Ascorbic acid; Degradation reactions; Dehydroascorbic acid; Kinetics; Storage; Thermal processing.
  10. A
    2017

    Molecular insights into prolyl and lysyl hydroxylation of fibrillar collagens in health and disease

    Rutger A F Gjaltema, Ruud A Bank

    This narrative review provides an updated overview of the complex process of creating mature collagen. The formation of collagen fibrils from precursor molecules involves many enzymes and chaperones in a series of steps…

    Bruck syndrome; Collagen; Ehlers–Danlos syndrome; connective tissue disorders; fibrosis; lysyl hydroxylation; osteogenesis imperfecta; prolyl hydroxylation.
  11. A+++
    2017

    Resveratrol supplementation reduces pain experience by postmenopausal women

    Rachel H X Wong, Hamish M Evans, Peter R C Howe

    This randomized, double-blind, placebo-controlled study investigated whether resveratrol supplementation could reduce pain and improve well-being in postmenopausal women. Over 14 weeks, participants taking 75 mg of resv…

    Resveratrolpolyphenolemenopause
  12. A
    2017

    Reconnecting the Body in Eastern and Western Medicine

    Helene M Langevin, Rosa N Schnyer

    Details for this 2017 publication, titled 'Reconnecting the Body in Eastern and Western Medicine' by Helene M. Langevin and Rosa N. Schnyer, have not yet been summarized. The title suggests a discussion comparing and in…

    acupunctureTCM
  13. A
    2017

    Spontaneous photon emission: A promising non-invasive diagnostic tool for breast cancer

    Xiaolei Zhao, Jingxiang Pang, Jialei Fu, Yong Wang, Meina Yang, Yanli Liu, Hua Fan, Liewei Zhang, Jinxiang Han

    In this animal study, researchers investigated if ultra-weak light emission from the body, called spontaneous photon emission (SPE), could detect breast cancer. They measured light from the skin of mice with breast canc…

    Breast cancerSpontaneous photon emission (SPE)Preliminary screeningCluster analysisOxidative metabolic
  14. A+++
    2017

    Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats

    Victor Fabricio, Jorge Camargo Oishi, Bruna Gabriele Biffe, Leandro Dias Gonçalves Ruffoni, Karina Ana da Silva, Keico…

    This animal study on rats investigated how resveratrol affects blood pressure and vascular function during estrogen deficiency, mimicking post-menopausal conditions. Researchers found that a lack of estrogen led to high…

    blood pressureresveratrolPostmenopause
  15. A+++
    2017

    Resveratrol regulates body weight in healthy and ovariectomized rats

    Rupali Sharma, Neel Kamal Sharma, M Thungapathra

    This animal study on rats investigated how the plant compound resveratrol affects body weight in both healthy subjects and those who had undergone ovariectomy, a model for menopause. The results suggest that resveratrol…

    OVX; Ovariectomy; Resveratrol; Soya free diet
  16. 1A++
    2017

    Microscopic anatomy of the visceral fasciae

    Carla Stecco, Maria Martina Sfriso, Andrea Porzionato, Anna Rambaldo, Giovanna Albertin, Veronica Macchi, Raffaele De C…

    Researchers examined the microscopic structure of visceral fascia—the connective tissue surrounding internal organs—from eight cadavers. They analyzed samples from the thorax, abdomen, and around organs like the heart,…

    elastic lamina; Gerota fascia; pericardium; peritoneum; serous membrane; visceral fascia; visceral manipulation.
  17. A++
    2017

    Oscillations of ultra-weak photon emission from cancer and noncancer cells stressed by culture medium change and TNF-alfa

    Pierre Madl, Thomas Verwanger, Mark Geppert, Felix Scholkmann

    All cells spontaneously emit a very faint light, known as ultra-weak photon emission (UPE). This study investigated how this light emission changes when different types of human cells, both cancerous and non-cancerous,…

    cancerBiophotonultraweak photon emission
  18. C
    2017

    Hypermobile Ehlers–Danlos Syndrome (a.k.a. Ehlers–Danlos Syndrome Type III and Ehlers–Danlos Syndrome Hypermobility Type): Clinical Description and Natural History

    Brad Tinkle, Marco Castori, Britta Berglund, Helen Cohen, Rodney Grahame, Hanadi Kazkaz, Howard Levy

    This 2017 review summarizes the clinical understanding of hypermobile Ehlers-Danlos syndrome (hEDS), thought to be the most common hereditary disorder of connective tissue. It is primarily characterized by musculoskelet…

    joint hypermobilityjoint hypermobility syndromeEhlers–Danlos syndrome type IIEhlers–Danlos syndrome hypermobility type
  19. B
    2017

    Stretching Reduces Skin Thickness and Improves Subcutaneous Tissue Mobility in a Murine Model of Systemic Sclerosis

    Y Xiong, L Berrueta, K Urso, Sara Olenich, Igla Muskaj, G J Badger, A Aliprantis, R Lafyatis, H M Langevin

    This animal study investigated the effects of stretching on systemic sclerosis, a condition that causes skin inflammation and fibrosis. Using a mouse model of the disease, researchers found that ten minutes of daily str…

    inflammationfibrosisSystemic sclerosisStretchingscleroderma
  20. A++
    2017

    Measuring ultra-weak photon emission as a non-invasive diagnostic tool for detecting early-stage type 2 diabetes: A step toward personalized medicine

    Mengmeng Sun, Eduard Van Wijk, Slavik Koval, Roeland Van Wijk, Min He, Mei Wang, Thomas Hankemeier, Jan van der Greef

    This study investigated whether ultra-weak photon emission (UPE)—a very faint light emitted by the body—could help identify different subtypes of pre-diabetes. Researchers had practitioners of Traditional Chinese Medici…

    biophotonsTraditional Chinese medicin-based diagnosticsPersonalized medicineType 2 diabetesUltra-weak photon emission (UPE)
  21. A++
    2017

    Spontaneous ultra-weak photon emission in correlation to inflammatory metabolism and oxidative stress in a mouse model of collagen-induced arthritis

    Min He, Eduard van Wijk, Herman van Wietmarschen, Mei Wang, Mengmeng Sun, Slavik Koval, Roeland van Wijk, Thomas Hankem…

    In this animal study, researchers investigated a mouse model of rheumatoid arthritis using two techniques: metabolomics (the analysis of metabolic products) and ultra-weak photon emission (UPE), which measures extremely…

    biophotonsUltra-weak photon emissionSystems biologyCollagen-induced arthritisCorrelation networks
  22. A++
    2017

    Massage therapy research review

    Tiffany Field

    This review summarizes research showing beneficial effects of massage therapy for a wide range of conditions, including prenatal depression, pain syndromes, autoimmune conditions, and issues related to aging. The author…

    Massage therapy research review
  23. B
    2017

    Cellulite: a review with a focus on subcision

    Daniel P Friedmann, Garrett Lane Vick, Vineet Mishra

    This narrative review examines cellulite, a common skin condition characterized by altered skin topography that primarily affects women on their buttocks and thighs. The authors discuss the potential underlying causes a…

    gynoid lipodystrophyfibrous septaeradiofrequencyvacuum-assisted subscision
  24. A++
    2017

    EFFECT OF MATRIX RHYTHM THERAPY (MRT) COMBINED WITH PHYSIOTHERAPY INTERVENTION IN FROZEN SHOULDER – A CASE REPORT

    Vijay Bhartiya, Shrikant Darade, Sandip Bhagwat, Manjumala Roy

    This case report describes the treatment of a 52-year-old man with a painful and stiff right shoulder, diagnosed as frozen shoulder. His condition also involved tendinosis, bursitis, and osteoarthritic changes. The pati…

    exercisesfrozen shoulderMRT
  25. C
    2017

    Concurrent validity of pain scales in individuals with myofascial pain and fibromyalgia

    Scott W Cheatham, Morey J Kolber, Monique Mokha, William J Hanney

    Researchers investigated the reliability of two common tools for measuring pain: the Numeric Pain Rating Scale (NPRS), where patients rate pain from 0 to 10, and the Visual Analog Scale (VAS). The study included 60 part…

    Myofascial painFibromyalgiapain scales
  26. A
    2017

    Human mesenchymal stem cells secrete hyaluronan-coated extracellular vesicles

    Uma Thanigai Arasu, Riikka Kärnä, Kai Härkönen, Sanna Oikari, Arto Koistinen, Heikki Kröger, Chengjuan Qu, Mikko J Lamm…

    Mesenchymal stem cells (MSCs) are known to help with tissue repair, partly by releasing tiny packages called extracellular vesicles (EVs). This study investigated the connection between these EVs and hyaluronan (HA), a…

    Hyaluronan; CD44; Extracellular vesicle; Stem cell; Filopodia; Hyaluronan synthase
  27. A
    2017

    Piezoelectric material – A promising approach for bone and cartilage regeneration

    Namdev More, Govinda Kapusetti

    This paper outlines a novel hypothesis for regenerating bone and cartilage, two weight-bearing tissues that are challenging to repair. Current treatments for damage from trauma or diseases like osteoarthritis have signi…

    tissue engineeringPiezoelectricityBone regenerationCartilage regeneration
  28. A+
    2017

    Quantitative tissue parameters of Achilles tendon and plantar fascia in healthy subjects using a handheld myotonometer

    Sarah Orner, Wolfgang Kratzer, Julian Schmidberger, Beate Grüner

    This study examined the mechanical properties of the Achilles tendon and plantar fascia in over 150 healthy adults using a handheld device called a MyotonPRO. The goal was to establish baseline normal values for tissue…

    fasciaachilles tendonplantar fasciaMyotonePRO
  29. B
    2017

    Evaluation of fascial manipulation in carpal tunnel syndrome

    Marco Pintucci, Marta Imamura, Aurore Thibaut, Lucas M de Exel Nunes, Mylene Mayumi Nagato, Helena H Kaziyama, Satiko T…

    Details for this study are not yet available. The research, published in 2017, appears to evaluate the effectiveness of Fascial Manipulation® for treating carpal tunnel syndrome. Without an abstract, further details abo…

    Fascial manipulationcarpal tunnel syndrome
  30. A+++
    2017

    The deep fascia and retinacula of the equine forelimb - structure and innervation

    Aleksandra Skalec, Monika Egerbacher

    This study investigated the deep fascia and its reinforcements (retinacula) in the equine forelimb using anatomical dissection and microscopic analysis. The researchers found that horse fascia is structurally similar to…

    equine; fascia; forelimb; innervation; retinaculum; structure
  31. A++
    2017

    Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes

    Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M Shaw

    This study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…

    Vitamin CsepsisIntensive careHypovitaminosis CCritical illness
  32. A
    2017

    Vitamin C for preventing atrial fibrillation in high risk patients: a systematic review and meta-analysis

    Harri Hemilä, Timo Suonsyrjä

    This systematic review and meta-analysis examined 15 trials to see if vitamin C could prevent atrial fibrillation in high-risk patients. The analysis, involving over 2000 subjects, found inconsistent results depending o…

    Ascorbic acidantioxidantArrhythmiaAtrial fibrillationCardiac surgery
  33. A++
    2017

    Vitamin C and Immune Function

    Anitra C Carr, Silvia Maggini

    This narrative review explores the crucial role of Vitamin C in the human immune system. As a potent antioxidant, it supports various functions in both the innate and adaptive immune responses, from strengthening the sk…

    ascorbate; ascorbic acid; immunity; immune system; neutrophil function; microbial killing; lymphocytes; infection; vitamin C
  34. A
    2017

    Calcium Signaling in Interstitial Cells: Focus on Telocytes

    Beatrice Mihaela Radu, Adela Banciu, Daniel Dumitru Banciu, Mihai Radu, Dragos Cretoiu, Sanda Maria Cretoiu

    This narrative review describes current knowledge on calcium signaling in a group of cells called interstitial cells, with a special focus on telocytes. These cells and their calcium signals are important for generating…

    telocytesinterstitial cellscalcium signalingCa2+ oscillationspacemaker activity
  35. B
    2017

    Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells

    Masahiro Ohgidani, Takahiro A Kato, Masako Hosoi, Makoto Tsuda, Kohei Hayakawa, Chie Hayaki, Rie Iwaki, Noriaki Sagata,…

    Researchers are investigating the role of brain immune cells called microglia in fibromyalgia. This study used a new technique to create microglia-like cells from the blood of people with fibromyalgia and healthy indivi…

    Fibromyalgiamikroglia
  36. B
    2017

    Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma

    Emmanuel Bäckryd, Lars Tanum, Anne-Li Lind, Anders Larsson, Torsten Gordh

    This study investigated signs of inflammation in people with fibromyalgia (FM). Researchers analyzed 92 different inflammation-related proteins in both blood plasma and cerebrospinal fluid from 40 FM patients, comparing…

    inflammationFibromyalgiacytokineschronic paincerebrospinal fluid
  37. A
    2017

    Telocytes heterogeneity: From cellular morphology to functional evidence

    Dragos Cretoiu, Beatrice Mihaela Radu, Adela Banciu, Daniel Dumitru Banciu, Sanda Maria Cretoiu

    This review discusses telocytes, a recently identified type of cell found throughout the connective tissue (stroma) of vertebrates. They are characterized by extremely long, thin extensions called telopodes, which form…

    cancertelocytesregenerative medicinestem cellsImmunophenotype heterogeneity
  38. C
    2017

    X-Rays Effects on Cytoskeleton Mechanics of Healthy and Tumor Cells

    Valeria Panzetta, Marta De Menna, Ida Musella, Mariagabriella Pugliese, Maria Quarto, Paolo A. Netti, Sabato Fusco

    This study investigated how X-ray radiation affects the internal structure, or cytoskeleton, of both healthy cells and tumor cells in a lab setting. Researchers exposed both cell types to different doses of radiation an…

    X-rays; Cytoskeleton; Mechanobiology; Focal Adhesion; Particle Tracking; Microrheology
  39. A+++
    2017

    Proinflammatory Cytokines and Oxidative Stress Decrease the Transport of Dopamine Precursor Tyrosine in Human Fibroblasts

    Ravi Vumma, Jessica Johansson, Nikolaos Venizelos

    This laboratory study investigated how inflammation and oxidative stress affect the transport of the amino acid tyrosine in human fibroblasts, a type of connective tissue cell. Tyrosine is a crucial precursor for the ne…

    Dopamine precursor; Human fibroblasts; Neuropsychiatric disorders; Oxidative stress; Proinflammatory cytokines; Tyrosine transport.
  40. B
    2017

    The Application of Acoustic Myography in Canine Muscle Function and Performance Testing

    Christina Fenger, Adrian P Harrison

    This animal study on 11 Labrador dogs used acoustic myography (AMG) to measure muscle activity during walking and trotting. Researchers focused on two muscles, the m. gluteus superficialis and m. longissimus lumborum, t…

    Mechanomyographym.longissimusm.glutealDogMuscle contraction
  41. A
    2017

    Rectus Capitis Posterior Minor

    Gabriel Venne, Brian J Rasquinha, Manuela Kunz, Randy E Ellis

    This cadaver study investigated the connection between a small neck muscle (Rectus Capitis Posterior Minor, RCPMi) and the spinal dura mater. Researchers used both microscopic analysis and biomechanical testing to clari…

    biomechanical testingcervical dura matermechanical influence of musclesmechanical influence of soft tissuerectus capitis posterior minor
  42. A
    2017

    What's in a name: Myofascial Release or Myofascial Induction?

    Leon Chaitow

    This commentary discusses two terms for a similar manual therapy technique: Myofascial Release (MFR) and Myofascial Induction Therapy (MIT). The author notes that while the techniques are virtually identical, the names…

    Myofascial releaseMyofascial Induction therapy
  43. A+++
    2017

    Early versus Delayed Rehabilitation after Acute Muscle Injury

    Monika L Bayer, Peter Magnusson, Michael Kjaer

    This research entry, titled "Early versus Delayed Rehabilitation after Acute Muscle Injury," is currently awaiting a detailed summary. The title suggests it explores the optimal timing for starting rehabilitation follow…

    Rehabilitationmuscle injurymechanical loading in rehabilitation
  44. A
    2017

    Don’t Forget the Abdominal Wall: Imaging Spectrum of Abdominal Wall Injuries after Nonpenetrating Trauma

    Shanna A Matalon, Reza Askari, Jonathan D Gates, Ketan Patel, Aaron D Sodickson, Bharti Khurana

    Abdominal wall injuries from non-penetrating trauma are relatively common but are often overlooked in the emergency department. This can happen because more severe, distracting injuries draw attention away, or because t…

    abdominal wallabdominal wall injuriesabdominal wall herniaabdominal wall muscle injurycostochondral rib injury
  45. B
    2017

    Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism

    Rosilene Cristina Rossetto Burgos, Johannes Cornelius Schoeman, Lennart Jan van Winden, Kateřina Červinková, Rawi Ramau…

    This laboratory study investigated a method for measuring oxidative stress, a process linked to many diseases. Researchers used a technique called ultra-weak photon emission (UPE) to monitor human cells in a dish after…

    Ultra-weak photon emission
  46. A
    2017

    Muscle strength and stiffness in resistance exercise: Force transmission in tissues

    Hans Chaudhry, Bruce Bukiet, Ellen Z Anderson, Jared Burch, Thomas Findley

    Researchers used a mathematical model to estimate how forces are transmitted through the quadriceps muscle during isometric resistance exercises. They specifically looked at how knee angle affects muscle stiffness, stre…

    Knee muscle strength; Stiffness; Mathematical modeling; Resistance exercise
  47. A
    2017

    The significance of closed kinematic chains to biological movement and dynamic stability

    Stephen Levin, Susan Lowell de Sol!orzano, Graham Scarr

    Biomechanical research has long focused on the body as a system of levers, but this review highlights the importance of "closed kinematic chains" (CKCs). These are continuous mechanical loops that couple multiple parts…

    biotensegrityBiomechanicsClosed-chainDevelopmentEvolution
  48. C
    2017

    Bi component T1p and T2 Relaxation Mapping of Skeletal Muscle In-Vivo

    Azadeh Sharafi, Gregory Chang, Ravinder R Regatte

    Researchers evaluated a specific MRI technique for creating more detailed images of skeletal muscle. Using what is known as T1ρ and T2 relaxation mapping on the calf muscles of healthy volunteers, they were able to dist…

    inflammationfibrosisskeletal musclebi-componentT2 relaxation
  49. A+++
    2017

    Electric Nutrition: The Surprising Health and Healing Benefits of Biological Grounding (Earthing)

    Stephen T Sinatra, James L Oschman, Gaétan Chevalier, Drew Sinatra

    This narrative review summarizes research on grounding (earthing), which involves direct physical contact with the Earth's surface. The authors suggest that grounding may provide a form of "electric nutrition" with pote…

    Grounding
  50. A
    2017

    The indeterminable resilience of the fascial system

    Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice Sacconi

    This commentary proposes a model of fascia not as layers, but as a network of polyhedral microvacuoles of connective tissue. These structures connect the body's systems and can change shape in response to tension, allow…

    fasciafibroblastManual TherapyOsteopathicfascial continuum
  51. A
    2017

    The Lumbodorsal Fascia as a Potential Source of Low Back Pain: A Narrative Review

    Jan Wilke, Robert Schleip, Werner Klingler, Carla Stecco

    This narrative review examines the role of the lumbodorsal fascia as a potential source of low back pain. Research shows this fascia contains pain-sensing nerve endings, which may be morphologically altered in people wi…

    fasciaNociceptionlow back painlumbodorsal fascia
  52. A+
    2017

    The nature and biology of basement membranes

    Ambra Pozzi, Peter D Yurchenco, Renato V Iozzo

    This review article discusses the nature and biology of basement membranes. These are thin, flexible sheets of tissue that line and separate different structures in the body. Once thought to be just passive scaffolding,…

    Collagen; laminin; heparan sulfate proteoglycan; discoidin domain receptor; integrin
  53. B
    2017

    Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis

    Hsin-Ying Huang, Ana Rivas-Caicedo, François Renevey, Hélène Cannelle, Elisa Peranzoni, Leonardo Scarpellino, Debbie L…

    This study investigated how antibody-producing plasma cells are supported within lymph nodes. Researchers identified a specific type of connective tissue cell, a medullary fibroblastic reticular cell (FRC), that forms a…

    FRC subsetslymph node medullaextrafollicular B cell differentiationplasma cell survivalhumoral response
  54. C
    2017

    S100A4 in cancer progression and metastasis: A systematic review

    Fei Fei, Jie Qu, Mingqing Zhang, Yuwei Li, Shiwu Zhang

    This systematic review examines the role of the protein S100A4 in cancer progression and metastasis. S100A4 is involved in the epithelial-mesenchymal transition, a key process that allows cancer cells to spread. The aut…

    metastasisS100A4malignant tumorepithelial-mesenchymal transition
  55. A
    2017

    The universal existence of myodural bridge in mammals: an indication of a necessary function

    Nan Zheng, Xiao-Ying Yuan, Yan-Yan Chi, Pei Liu, Bing Wang, Jia-Ying Sui, Seung-Ho Han, Sheng-Bo Yu, Hong-Jin Sui

    The myodural bridge is a connective tissue structure linking one of the deep, upper neck muscles to the spinal dura mater. This anatomical study investigated whether this structure, known in humans, also exists in other…

    Myodural Bridge
  56. A++
    2017

    Minimizing Injury and Maximizing Return to Play: Lessons from Engineered Ligaments

    Keith Baar

    Musculoskeletal injuries are a primary reason for time away from sports, partly because our understanding of how training affects tendons and ligaments is limited. This study used engineered ligaments grown in a lab fro…

    trainingminimizing injuryreturn to playsupplementation
  57. A++
    2017

    A New Definition of an Acupuncture Meridian

    Fletcher Kovich

    This perspective article proposes a new definition of acupuncture meridians, moving away from the idea of dedicated anatomical vessels. The author suggests that meridians are actually tracts of tissue that become affect…

    acupunctureelectrical wavesemiconductionsignal propagation
  58. B
    2017

    All you need to know about the AIP diet

    Lana Burgess

    This article reviews the Autoimmune Protocol (AIP) diet, which aims to reduce inflammation and relieve symptoms of autoimmune disorders. The diet is based on the idea that problems with the gut wall, sometimes called 'l…

    inflammationAutoimmune protocolautoimmune disease
  59. A++
    2017

    A Curious Oversight in Acupuncture Research

    Fletcher Kovich

    In this perspective article, the author argues that current acupuncture hypotheses overlook a crucial factor: the speed at which the treatment takes effect. Observations suggest that communication between acupoints and…

    acupunctureelectrical wavesemiconductionsignal propagation
  60. A+++
    2017

    Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study

    John F Pearson, Juliet M Pullar, Renee Wilson, Janet K Spittlehouse, Margreet C M Vissers, Paula M L Skidmore, Jinny Wi…

    This cohort study examined vitamin C status in 404 fifty-year-olds in New Zealand. Researchers measured the concentration of vitamin C in participants' blood plasma as well as their dietary intake. The results showed th…

    ascorbate; cognition; HbA1c; insulin; glucose; hypovitaminosis C