Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)
This study investigated the role of Yes-associated protein (YAP) in the mechanobiology of deep fascia, specifically the thoracolumbar fascia. Researchers analyzed tissue samples from patients and found that YAP acts as…
The Combined Effect of Static Stretching and Foam Rolling With or Without Vibration on the Range of Motion, Muscle Performance, and Tissue Hardness of the Knee Extensor
This study investigated how the order of static stretching (SS) and foam rolling (FR), with or without vibration, affects range of motion, muscle strength, and tissue hardness in the quadriceps. The results showed that…
Urinary Incontinence and Other Pelvic Floor Dysfunctions as Underestimated Problems in People under Forty Years: What Is Their Relationship with Sport?
Urinary incontinence is still an underestimated problem due to its anatomical complexity and social taboo. Most of the time, it is believed to affect predominantly the elderly female population, and the literature still…
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19
Researchers investigated the link between the gut microbiome and the severity of COVID-19. In this cohort study, they analyzed stool and blood samples from 100 patients and compared them to individuals without COVID-19.…
Prevalence and risk factors for menopausal symptoms in middle-aged Chinese women: a community-based cross-sectional study
This community-based cross-sectional study examined the prevalence of menopausal symptoms among over 6,000 middle-aged Chinese women. The findings indicate that symptoms are most prevalent during the menopausal transiti…
Hyaluronic Acid in Postmenopause Vaginal Atrophy: A Systematic Review
This systematic review evaluated the effectiveness of hyaluronic acid as a treatment for vaginal atrophy in postmenopausal women. By analyzing five primary studies, researchers found that hyaluronic acid appears to offe…
Menopause, Ultraviolet Exposure, and Low Water Intake Potentially Interact with the Genetic Variants Related to Collagen Metabolism Involved in Skin Wrinkle Risk in Middle-Aged Women
This observational study of 128 middle-aged women examined how genetic variants related to collagen metabolism interact with lifestyle factors to influence wrinkle development. Researchers found that women with a high p…
Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight Loss
This literature review examines the effects of time-restricted eating (TRE), intermittent fasting (IF), and fasting-mimicking diets (FMD) on weight loss. While these interventions are popular for their potential health…
Vascular Stiffness in Aging and Disease
This narrative review examines how vascular stiffness, particularly in the aorta, increases with age and contributes to various cardiovascular diseases. Research suggests that stiffness often progresses more significant…
Recent advances in the anti-aging effects of phytoestrogens on collagen, water content, and oxidative stress
This narrative review examines how phytoestrogens, plant-derived compounds that mimic human estrogen, may influence skin aging processes. Research suggests these molecules can help counteract the decline in collagen and…
Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study
This 24-month randomized, double-blind, placebo-controlled crossover study investigated the effects of daily resveratrol supplementation in 125 postmenopausal women. The researchers found that regular intake of 75 mg re…
Tissue Micro-channels Formed by Collagen Fibers and their Internal Components: Cellular Evidence of Proposed Meridian Conduits in Vertebrate Skin
This study examined fascia from various vertebrate species using microscopy to search for physical structures that might correspond to the meridian conduits described in Traditional Chinese Medicine (TCM). Researchers i…
Regular Supplementation With Resveratrol Improves Bone Mineral Density in Postmenopausal Women: A Randomized, Placebo-Controlled Trial
This randomized, placebo-controlled trial investigated how daily resveratrol supplementation affects bone health in postmenopausal women. Over 12 months, participants taking 75 mg of resveratrol twice daily showed incre…
Narrative review of the epidemiology, diagnosis and pathophysiology of pelvic organ prolapse
This narrative review examines the epidemiology and causes of pelvic organ prolapse (POP), a condition affecting many women's quality of life. The authors highlight a discrepancy in prevalence rates, noting that while a…
Role of vitamin K 2 in bone metabolism: a point of view and a short reappraisal of the literature
This narrative review examines the role of Vitamin K2 in bone metabolism and its contribution to maintaining skeletal integrity. Vitamin K2 is essential for activating osteocalcin, a key protein that binds calcium to th…
Ankle Motion Is Associated With Soft Tissue Displacement in the Dorsal Thigh: An in vivo Investigation Suggesting Myofascial Force Transmission Across the Knee Joint
This study investigated how ankle motion affects tissue in the back of the thigh. Researchers passively stretched the calves of healthy participants lying prone with an extended knee. Using ultrasound, they observed tha…
The Rolf Method of Structural Integration and Pelvic Floor Muscle Facilitation: Preliminary Results of a Randomized, Interventional Study
This randomized, interventional study investigated how the Rolf Method of Structural Integration (SI) affects pelvic floor muscle function in healthy women. Thirty-three women were divided into two groups; one received…