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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–4 of 4 studiesVitamin CA++Since 2010
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  1. A++
    2018

    Ascorbic acid in cancer treatment: let the phoenix fly

    Niraj Shenoy, Edward Creagan, Thomas Witzig, Mark Levine

    This review article discusses the renewed interest in Vitamin C (ascorbic acid) as a potential anti-cancer agent. When administered intravenously, Vitamin C can reach much higher concentrations in the body than when tak…

    cancerVitamin Cascorbatepharmacokinetics
  2. A++
    2017

    Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes

    Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M Shaw

    This study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…

    Vitamin CsepsisIntensive careHypovitaminosis CCritical illness
  3. A++
    2015

    Fruit, vegetable and vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children

    A S Donin, J E Dent, C M Nightingale, N Sattar, C G Owen, A R Rudnicka, M R Perkin, A M Stephen, S A Jebb, D G Cook, P…

    This cross-sectional study of over 2000 children in the UK examined the relationship between vitamin C and risk factors for type 2 diabetes. Researchers found that higher levels of vitamin C in the blood were associated…

    Vitamin Cinsulin resistensglycaemiadiabetes type 2
  4. A++
    2013

    Vitamin C in Disease Prevention and Cure: An Overview

    Shailja Chambial, Shailendra Dwivedi, Kamla Kant Shukla, Placheril J John, Praveen Sharma

    This narrative review provides an overview of Vitamin C's many roles in the body. It is essential for developing and maintaining connective tissues, and plays a key part in bone formation, wound healing, and gum health.…

    cancerdiabetesVitamin CImmunityinfertility