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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–4 of 4 studieshyaluronan1A+With summary
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  1. 1A+
    2018

    The Fasciacytes- A New Cell Devoted To Fascial Gliding Regulation

    Carla Stecco, Caterina Fede, Veronica Macchi, Andrea Porzionato, Lucia Petrelli, Carlo Biz, Robert Stern, Raffaele De C…

    Researchers have identified a new type of cell within fascia, which they have named "fasciacytes." This study presents evidence that these specialized cells are responsible for producing hyaluronan, a key component of t…

    hyaluronanfasciafasciacytesextracellular matrix
  2. 1A+
    2014

    Painful Connections: Densification Versus Fibrosis of Fascia

    P G Pavan, Antonio Stecco, R Stern, Carla Stecco

    In this review article, the authors describe two types of fascial changes that can cause pain: densification and fibrosis. Densification is described as a reversible alteration in the viscosity of the loose connective t…

    hyaluronanfasciafibrosisdensificationConnective tissue
  3. 1A+
    2007

    Hyaluronan in Tissue Injury and Repair

    Dianhua Jiang, Jiurong Liang, Paul W Noble

    This 2007 review article explores the complex role of hyaluronan (HA), a component of the extracellular matrix, in tissue injury and repair. The authors describe how HA's function depends on its size: while the large, n…

    hyaluronaninflammationtissue repair
  4. 1A+
    2001

    Hyaluronan and its catabolic products in tissue injury and repair

    P W Noble

    This narrative review explores the role of hyaluronan (HA), a common component of connective tissue, in the body's response to injury. In healthy tissues, HA exists as a large molecule that helps maintain structural int…

    hyaluronaninflammationCD44respons to injury