Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2015
The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients
Jean-Alexandre Boucher, Jacques Abboud, François Nougarou, Martin C Normand, Martin DescarreauxThis study compared trunk muscle control between people with chronic low back pain (cLBP) and healthy individuals. Researchers found that the cLBP group was less accurate at reproducing a specific amount of force with t…
fascialow back painmuscle fatiguevibration - A2015
The effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases
James L Oschman, Gaétan Chevalier, Richard BrownThis report summarizes research on the effects of "grounding" or "earthing," which involves direct electrically conductive contact with the Earth's surface. The research suggests this contact may influence the body's ph…
fasciachronic inflammationimmune systemwound repairwhite blood cells - A2015
New Developments in the Primo Vascular System: Imaging and Functions with regard to Acupuncture
Richard C Niemtzow, Kwang-Sup Soh, Kyung A Kang, John H Barker, He Sheng Luo, Moriya OhkumaThis research entry, for which only the title is available, appears to discuss recent advancements in understanding the primo vascular system. The title suggests a focus on new imaging techniques and the system's functi…
acupunctureprimo vascular systemeditorial - B2015
The extracellular matrix: Tools and insights for the “omics” era
A Nabaa, K R Clauser, H Dingd, C A Whittaker, S A Carrc, R O HynesaThis narrative review discusses the extracellular matrix (ECM), the complex network of proteins and molecules that provides structural and chemical support to our cells and tissues. Alterations in the ECM are associated…
extracellular matrixMatrisomeMatrisomeDBECM atlasBioinformatics - A2015
Effects of non-pharmacological interventions on inflammatory biomarker expression in patients with fibromyalgia: a systematic review
Kenji Sanada, Marta Alda Díez, Montserrat Salas Valero, María Cruz Pérez-Yus, Marcelo M P Demarzo, Mauro García-Toro, J…This systematic review examined how non-drug treatments affect inflammatory markers in people with fibromyalgia. Researchers analyzed 12 studies involving 536 participants who underwent exercise, dietary, or multidiscip…
fasciaFibromyalgiapaincytokinessleep quality - C2015
Proteoglycan form and function: A comprehensive nomenclature of proteoglycans
Renato V Iozzo, Liliana SchaeferIn this review article, the authors propose a new, comprehensive classification system for proteoglycans, a group of molecules important to connective tissue structure and function. The classification is based on three…
GlycosaminoglycanAngiogenesisProteoglycanCancer growthGrowth factor modulation - B2015
Fibromyalgia: A Critical and Comprehensive Review
Andrea T Borchers, M Eric GershwinThis comprehensive review discusses fibromyalgia as a complex disorder within a spectrum of medically unexplained syndromes. Characterized by widespread pain, fatigue, and sleep disturbances, it is often associated with…
FibromyalgiaChronicpainOpiatesPatient supportTrauma - A2015
Primo Vascular System: An Endothelial-to-Mesenchymal Potential Transitional Tissue Involved in Gastric Cancer Metastasis
An Ping, Su Zhendong, Qu Rongmei, Dai Jingxing, Chen Wei, Zhou Zhongyin, Luo Hesheng, Kwang-Sup SohThe primo vascular system (PVS) is described as a distinct circulatory network beyond the blood and lymphatic systems. This study investigated the role this system might play in the spread of gastric cancer. The researc…
fasciacancermetastasisprimo vascular system - A++2015
Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology
Jaime M Cyphert, Carol S Trempus, Stavros GarantziotisThis narrative review summarizes current knowledge about hyaluronan, a molecule whose biological effects are dependent on its size. Unlike many other molecules, hyaluronan's signaling properties are determined not by ch…
hyaluronanCell signalingmolecular size - A2015
Primo Vascular System: A Unique Biological System Shifting a Medical Paradigm
Bruno Chikly, Paul Roberts, Jörgen QuaghebeurThis article describes the primo vascular system (PVS), a unique biological system distinct from the arteriovenous and lymphatic systems. Research suggests the PVS has immune and endocrine functions and plays a role in…
fasciaprimo vascular system - 1A+2015
Electron microscopy of human fascia lata: focus on telocytes
Joanna Dawidowicz, Sylwia Szotek, Natalia Matysiak, Łukasz Miela!nczyk, Krzysztof MaksymowiczThis study used an electron microscope to examine the types of cells present in the fascia lata, a sheet of connective tissue in the thigh. For the first time, researchers confirmed the existence of a specific cell type…
Fibroblastsmyofibroblastshuman fascia latatransmission electron microscopytelocytes - A+2015
Changes in electrical pain threshold of fascia and muscle after initial and secondary bouts of elbow flexor eccentric exercise
Wing Yin Lau, Anthony J. Blazevich, Michael J. Newton, Sam Shi Xuan Wu, Kazunori NosakaThis study investigated how pain sensitivity changes in fascia and muscle after strenuous eccentric exercise. Ten young men performed two bouts of maximal eccentric elbow curls, four weeks apart. After the first session…
pressure pain thresholdmuscle damageRepeated bout effectDelayed onset muscle sorenessVisual analogue scale