Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesRole of Hyaluronan in Inflammatory Effects on Human Articular Chondrocytes
Some researchers have proposed that fragments of hyaluronan (HA), a key molecule in connective tissue, can trigger inflammation in cartilage. This study investigated that idea in human articular cartilage cells. Researc…
Hyaluronan: molecular size-dependent signaling and biological functions in inflammation and cancer
This narrative review explores how hyaluronan (HA), a key component of the extracellular matrix, functions differently depending on its molecular size. Large, high-molecular weight HA has different biological properties…
The fascial breath
This narrative review proposes a new way of understanding the diaphragm muscle, moving beyond a purely mechanical view. The authors argue that the diaphragm is not just covered by fascia but is fundamentally a fascial t…
Biotensegrity or Fascintegrity
In this theoretical review, the authors question the popular "biotensegrity" model for describing the body's mechanics. They argue the model is incomplete because it fails to account for crucial factors like bodily flui…
Vitamin C: an essential “stress hormone” during sepsis
The body's stress response involves hormones like cortisol and catecholamines, but in most mammals, it also includes increased production of vitamin C. These substances work together to protect the body from damage duri…
Effects of season long participation on ACL volume in female intercollegiate soccer athletes
This study investigated how a competitive season affects the anterior cruciate ligament (ACL) in female collegiate soccer players. Researchers used MRI scans to measure ACL volume in 17 athletes before and after their s…
Effects of foam rolling on performance and recovery: A systematic review of the literature to guide practitioners on the use of foam rolling
This systematic review analyzed 49 studies to understand how foam rolling affects athletic performance and recovery. The authors found evidence that foam rolling can decrease muscle stiffness and improve range of motion…
Ultrasound Imaging of the Fascial Layers
This publication, for which a full summary is not yet available, appears to discuss using ultrasound to visualize the body's fascial layers. Ultrasound imaging is a non-invasive technique that provides real-time views o…
Vitamin C and Neutrophil Function: Findings from Randomized Controlled Trials
This systematic review examined how vitamin C supplementation affects neutrophils, a key type of immune cell. Researchers analyzed 16 randomized controlled trials that measured neutrophil functions like their ability to…
A Primitive Trait in Two Breeds of Equus Caballus Revealed by Comparative Anatomy of the Distal Limb
This comparative anatomy study investigated the lower limbs of 574 equids, including 18 horse breeds, donkeys, zebras, and Przewalski's horses. Researchers looked for two specific ligamentous structures that are remnant…
High Cortisol and the Risk of Dementia and Alzheimer's Disease: A Review of the Literature
This literature review examines the relationship between the stress hormone cortisol and the risk of dementia and Alzheimer’s disease. The research suggests that chronically elevated cortisol levels may have deleterious…
Development of a biotensegrity focused therapy for the treatment of pelvic organ prolapse: A retrospective case series
This retrospective case series explores a new biotensegrity-focused therapy for pelvic organ prolapse (POP). Challenging the common view that POP is caused by weak tissue, this approach hypothesizes that the condition i…