Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2019
Collagen changes in pelvic support tissues in women with pelvic organ prolapse
Runqi Gong, Zhijun XiaThis narrative review summarizes research on how changes in collagen are linked to pelvic organ prolapse in women. Collagen is a critical component of the pelvic floor, providing essential supportive functions. Studies…
extracellular matrixcollagenBiomechanicsPelvic organ prolapseSignaling pathways - A2019
Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis
Tabea C Hornung, Hans-Konrad BiesalskiUnlike many animals, humans cannot produce their own vitamin C. This study explores a potential evolutionary advantage of this loss. Researchers compared red blood cells from humans and pigs (who can make vitamin C) and…
glucose transporter; vitamin C; gulono-lactone-oxidase; vitamin C recycling - A++2019
A prophylactic effect of local vibration on quadriceps muscle fatigue in non-athletic males: a randomized controlled trial study
Khadijeh Otadi, Mehri Ghasemi, Shohreh Jalaie, Hossein Bagheri, Morteza Azizian, Saeid Emamdoost, Hadi Sarafraz, Mustap…This randomized controlled trial investigated whether local vibration could prevent muscle fatigue. Thirty healthy, non-athletic young men were divided into two groups: one received two minutes of vibration on their qua…
Musclefatiguevibration - B2019
Extracellular matrix composition of connective tissues: a systematic review and meta-analysis
Turney J McKee, George Perlman, Martin Morris, Svetlana V KomarovaThis systematic review and meta-analysis compiled data to quantify the protein composition of the extracellular matrix (ECM) in various human connective tissues. Researchers analyzed data from studies on bone, adipose t…
extracellular matrixmatrix remodelingcollagen content - A2019
Evaluation of the Structure of Myodural Bridges in an Equine Model of Ehlers-Danlos Syndromes
Abigail McElroy, Ann Rashmir, Jane Manfredi, Dodd Sledge, Elizabeth Carr, Edward Stopa, Petra KlingeThis animal study investigated myodural bridges—connective tissue links between small neck muscles and the spinal cord's outer covering (dura mater)—in horses. Researchers compared horses with a genetic connective tissu…
Myodural BridgeEhlers-danlos syndromes - A+2019
Anti-Inflammatory Diets and Fatigue
Ulrike Hass, Catrin Herpich, Kristina NormanThis narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…
anti-inflammatory nutrition; cancer; chronic fatigue; cytokines; fatigue reduction diet; inflammation; myalgic encephalomyelitis; omega-3 fatty acids; polyphenols; probiotics. - A2019
Existence and features of the myodural bridge in Gallus domesticus: indication of its important physiological function
Ya-Ru Dou, Nan Zheng, Jing Gong, Wei Tang, Chukwuemeka Samuel Okoye, Ying Zhang, Yu-Xiao Chen, Yu Zhang, Shi-Yi Pi, Lia…In this anatomical animal study, researchers investigated the existence of the myodural bridge (MDB) in chickens. The MDB is a dense connective tissue that links muscles in the upper neck to the spinal dura mater. The i…
Myodural Bridgecerebrospinal fluid circulationCollagen fiberGallus domesticus - A+2019
Overuse Injury: The Result of Pathologically Altered Myofascial Force Transmission?
Jan Wilke, Andry Vleeming, Scott WearingIn this narrative review, the authors propose a new perspective on overuse injuries. Traditionally, therapy focuses on the site of pain, viewing the injury as the result of local, repetitive microdamage. The authors hyp…
Myofascial force transmissionoveruse injuryfascitismusculoskeletal disorder - A++2019
Development of a biotensegrity focused therapy for the treatment of pelvic organ prolapse: A retrospective case series
Anna Crowle, Clare HarleyThis retrospective case series explores a new biotensegrity-focused therapy for pelvic organ prolapse (POP). Challenging the common view that POP is caused by weak tissue, this approach hypothesizes that the condition i…
Myofascial releasebiotensegrityPelvic organ prolapsePelvic tension - A2019
Effects of foam rolling on performance and recovery: A systematic review of the literature to guide practitioners on the use of foam rolling
Sharief Hendricks, Hayd'n Hill, Steve den Hollander, Wayne Lombard, Romy ParkerThis systematic review analyzed 49 studies to understand how foam rolling affects athletic performance and recovery. The authors found evidence that foam rolling can decrease muscle stiffness and improve range of motion…
FlexibilityFoam rollingPerformanceRecovery - A++2019
A History of Fascia
Sue Adstrum, H NicholsonThis historiographic review surveys how the anatomical term "fascia" has been portrayed throughout history. The authors found that its meaning has varied considerably during the 400 years the term has been used in Engli…
anatomical terminology; fascia; fascial system; integrative anatomy; medical history - A+++2019
A comparative multi-site and whole-body assessment of fascia in the horse and dog: a detailed histological investigation
Waqas Ahmed, Marta Kulikowska, Trine Ahlmann, Lise C Berg, Adrian P Harrison, Vibeke Sødring ElbrøndThis animal study compared the microscopic structure of fascia in horses and dogs across multiple body regions. Researchers found that horse fascia is generally tight and dense, while dog fascia is looser and more simil…
deep fascia; dog; histology; horse; hypodermis; myofascial kinetic lines; superficial fascia.