TGF-beta1
3 studies on TGF-beta1 — reviewed, translated, woven together.
Articles
Nothing here yet.
Research
- 2015
Hyaluronan Regulates Bone Morphogenetic Protein-7- dependent Prevention and Reversal of Myofibroblast Phenotype
Adam C Midgley, Lucy Duggal, Robert Jenkins, Vincent Hascall, Robert Steadman, Aled O Phillips, Soma MeranThis study on human lung fibroblasts investigated how a protein called BMP7 might counteract fibrosis. Researchers found that BMP7 can prevent and even reverse the formation of myofibroblasts, which are cells that contr…
- 2012
Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism
Jun Li, Daniel J Gorski, Wendy Anemaet, Jennifer Velasco, Jun Takeuchi, John D Sandy, Anna PlaasIn this mouse study, researchers investigated how hyaluronan (HA) injections might protect joints in osteoarthritis. They found that even though the injected HA was cleared from the knee joint in under two hours, a sing…
- 2008
Tissue Stretch Decreases Soluble TGF-β1 and Type-1 Procollagen in Mouse Subcutaneous Connective Tissue: Evidence From Ex Vivo and In Vivo Models
N A Bouffard, K R Cutroneo, G J Badger, S L White, T R Buttolph, H P Ehrlich, D Stevens-Tuttle, H M LangevinThis study on mice investigated how brief, static stretching affects connective tissue healing after an injury. Researchers used two models: tissue samples cultured outside the body (ex vivo) and live mice with minor su…
Podcast
Nothing here yet.