RAS-RAF-MEK-ERK signaling pathway; apoptosis; invasiveness; malignant melanoma; vitamin C

Vitamin C at high concentrations induces cytotoxicity in malignant melanoma but promotes tumor growth at low concentrations

This study investigated how different concentrations of Vitamin C affect malignant melanoma in both cell cultures and animal models. The results suggest that high concentrations (millimolar levels) can induce cancer cel…