Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration
Bingjin Wang, Wencan Ke, Kun Wang, Gaocai Li, Liang Ma, Saideng Lu, Qian Xiang, Zhiwei Liao, Rongjin Luo, Yu Song, Wenb…
This study investigates how the mechanical environment of the intervertebral disc influences cellular health during disc degeneration. Researchers found that as the central part of the disc (nucleus pulposus) becomes st…
