metastasis
5 studies on metastasis — reviewed, translated, woven together.
Articles
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Research
- 2019
High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition
Ling-Hui Zeng, Qing-Mei Wang, Lin-Yi Feng, Yu-Dun Ke, Qian-Zi Xu, An-Yi Wei, Chong Zhang, Rong-Biao YingThis study on breast cancer cells in the lab and in mice explored how different doses of vitamin C affect cancer cell behavior. Researchers found that low and medium doses of vitamin C seemed to encourage cancer cells t…
- 2017
S100A4 in cancer progression and metastasis: A systematic review
Fei Fei, Jie Qu, Mingqing Zhang, Yuwei Li, Shiwu ZhangThis systematic review examines the role of the protein S100A4 in cancer progression and metastasis. S100A4 is involved in the epithelial-mesenchymal transition, a key process that allows cancer cells to spread. The aut…
- 2016
Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs
Agata Jabłońska-Trypuć, Marzena Matejczyk, Stanisław RosochackiThis review article describes matrix metalloproteinases (MMPs), the primary enzymes responsible for breaking down collagen in the extracellular matrix. This breakdown process is normal and necessary for tissue remodelin…
- 2015
Primo Vascular System: An Endothelial-to-Mesenchymal Potential Transitional Tissue Involved in Gastric Cancer Metastasis
An Ping, Su Zhendong, Qu Rongmei, Dai Jingxing, Chen Wei, Zhou Zhongyin, Luo Hesheng, Kwang-Sup SohThe primo vascular system (PVS) is described as a distinct circulatory network beyond the blood and lymphatic systems. This study investigated the role this system might play in the spread of gastric cancer. The researc…
- 2013
Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin-C deficient mice
John Cha, M Waheed Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias RathThis animal study investigated how Vitamin C (ascorbate) supplementation affects cancer growth in mice that, like humans, cannot produce their own. Researchers injected melanoma or breast cancer cells into two groups of…
Podcast
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