mechanosensing
3 studies on mechanosensing — reviewed, translated, woven together.
Articles
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Research
- 2016
Internal strain drives spontaneous periodic buckling in collagen and regulates remodeling
Andrew Dittmore, Jonathan Silver, Susanta K Sarkar, Barry Marmer, Gregory I Goldberg, Keir C NeumanThis study investigated how collagen, a key structural protein, is remodeled. Researchers observed that the enzymes responsible for breaking down collagen, called MMPs, bind to specific, vulnerable spots that appear at…
- 2014
Mechanotransduction and extracellular matrix homeostasis
Jay D Humphrey, Eric R Dufresne, Martin A SchwartzConnective tissues are dynamic, constantly adapting even at rest. Cells within these tissues continually sense mechanical cues from their environment through a process called mechanotransduction. In response, they maint…
- 2006
Connective tissue: A body-wide signaling network?
H M LangevinThis paper proposes that loose connective tissue functions as a body-wide communication system, in addition to its structural role. The author hypothesizes that this tissue network is mechanosensitive, meaning it respon…
Podcast
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