mechanobiology
6 studies on mechanobiology — reviewed, translated, woven together.
Articles
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Research
- 2019
Mechanobiology of cells and cell systems, such as organoids
Ece Bayir, Aylin Sendemir, Yannis F MissirlisThis review discusses organoids, which are three-dimensional tissues grown in a lab that self-organize to mimic organ development. While organoids offer great potential for disease modeling and drug development, little…
- 2018
Cellular Mechanotransduction: From Tension to Function
F Martino, A R Perestrelo, V Vinarský, S Pagliari, G ForteIn this review article, the authors describe mechanotransduction—the process by which cells sense and respond to physical forces from their environment, such as the extracellular matrix. These mechanical cues are conver…
- 2012
Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity
Melody A Swartz, Amanda W LundThis review explores how tumors interact with the lymphatic system to grow and spread. Increased fluid flow from a tumor to nearby lymph nodes does more than just transport cancer cells. This flow also creates mechanica…
- 2008
Mechanotransduction – a field pulling together?
Christopher S ChenIn this 2008 review article, the author discusses mechanotransduction, the process by which cells convert mechanical forces into biochemical signals. Cells are constantly subjected to forces, both from external pressure…
- 2007
Interstitial Flow and Its Effects in Soft Tissues
Melody A Swartz, Mark E FleuryThis 2007 review article summarizes knowledge about interstitial flow, which is the movement of fluid in the spaces between cells in the body's soft tissues. The authors describe how this flow is critical for tissue dev…
- 2003
Tensegrity II. How structural networks influence cellular information processing networks
Donald E IngberThis theoretical article, the second in a two-part series, explores how a cell's physical structure influences its internal signaling and behavior. It builds on the "tensegrity" model, which describes the cell's skeleto…
Podcast
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