cytokines
10 studies on cytokines — reviewed, translated, woven together.
Articles
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Research
- 2021
Impaired Lymphatic Drainage and Interstitial Inflammatory Stasis in Chronic Musculoskeletal and Idiopathic Pain Syndromes: Exploring a Novel Mechanism
Brian Tuckey, John Srbely, Grant Rigney, Meena Vythilingam, Jay ShahIn this theoretical paper, the authors propose a potential mechanism for chronic pain syndromes. They hypothesize that impaired lymphatic drainage following trauma or an immune response can trap inflammatory substances…
- 2020
Manipulation of the Fascial System Applied During Acute Inflammation of the Connective Tissue of the Thoracolumbar Region Affects Transforming Growth Factor-β1 and Interleukin-4 Levels: Experimental Study in Mice
Maria Elisa Duarte França, Larissa Sinhorim, Daniel Fernandes Martins, Robert Schleip, Nicolas A M M Machado-Pereira, G…This animal study investigated the effects of manual fascial manipulation on acute inflammation in the connective tissue of mice's lower backs. Researchers induced inflammation and then applied a specific manipulation p…
- 2020
Pilates exercise improves the clinical and immunological pro!les of patients with human T-cell lymphotropic virus 1 associated myelopathy: A pilot study
Altair Vallinoto Klautau, Denise da Silva Pinto, Bárbara Brasil Santana, Maria Alice Freitas Queiroz, Andréa Nazar!e M…This pilot study investigated the effects of a 10-week Pilates program for eight patients with the chronic inflammatory disease HAM/TSP. After the exercise period, participants experienced significant improvements in pa…
- 2017
Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma
Emmanuel Bäckryd, Lars Tanum, Anne-Li Lind, Anders Larsson, Torsten GordhThis study investigated signs of inflammation in people with fibromyalgia (FM). Researchers analyzed 92 different inflammation-related proteins in both blood plasma and cerebrospinal fluid from 40 FM patients, comparing…
- 2015
Cytokines in rheumatoid arthritis - shaping the immunological landscape
Iain B McInnes, Christopher D Buckley, John D IsaacsIn this short opinion article, the authors provide an overview of the central role of cytokines in rheumatoid arthritis (RA). These signaling molecules are involved in the immune responses associated with both the onset…
- 2015
Effects of non-pharmacological interventions on inflammatory biomarker expression in patients with fibromyalgia: a systematic review
Kenji Sanada, Marta Alda Díez, Montserrat Salas Valero, María Cruz Pérez-Yus, Marcelo M P Demarzo, Mauro García-Toro, J…This systematic review examined how non-drug treatments affect inflammatory markers in people with fibromyalgia. Researchers analyzed 12 studies involving 536 participants who underwent exercise, dietary, or multidiscip…
- 2013
TGF-β: Guardian of T Cell Function
Soyoung A Oh, Ming O LiIn this review article, the authors discuss the role of the cytokine TGF-β (transforming growth factor-beta) in the immune system. TGF-β is critical for regulating T cells, a type of white blood cell central to the adap…
- 2012
Hyaluronan differently modulates TLR-4 and the inflammatory response in mouse chondrocytes
Giuseppe M Campo, Angela Avenoso, Angela D’Ascola, Vera Prestipino, Michele Scuruchi, Giancarlo Nastasi, Alberto Calatr…This study on mouse cartilage cells investigated how different sizes of hyaluronan (HA) affect inflammation. Researchers found that small HA fragments increased the production of several inflammatory markers. In contras…
- 2010
Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
Beatrix Bartok, Gary S FiresteinRheumatoid arthritis (RA) is a complex disease involving multiple immune cells. This review highlights the crucial role of fibroblast-like synoviocytes (FLS), cells in the joint lining that become unusually aggressive i…
- 2008
The inflammatory response to cell death
K L Rock, H KonoThis 2008 review article explores how the body responds when cells die from injury rather than infection. Such cell death triggers an inflammatory response that is essential for host defense and tissue repair. However,…
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