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3
- 2016
Coordinated integrin activation by actin-dependent force during T-cell migration
P Nordenfelt, H L Elliott, T A SpringerResearchers investigated how immune cells, specifically T-cells, generate the force needed to move. Using fluorescent tension sensors, they visualized the tension within integrins, which are proteins that help cells gri…
- 2006
Viscoelastic Retraction of Single Living Stress Fibers and Its Impact on Cell Shape, Cytoskeletal Organization, and Extracellular Matrix Mechanics
Sanjay Kumar, Iva Z Maxwell, Alexander Heisterkamp, Thomas R Polte, Tanmay P Lele, Matthew Salanga, Eric Mazur, Donald…Cells maintain their shape and interact with their surroundings using internal tension cables called stress fibers. Using a microscopic laser to cut individual stress fibers inside living cells, researchers studied how…
- 2006
Fibroblast spreading induced by connective tissue stretch involves intracellular redistribution of a- and b-actin
Helene M Langevin, Kirsten N Storch, Marilyn J Cipolla, Sheryl L White, Thomas R Buttolph, Douglas J TaatjesResearchers investigated how fibroblasts, the primary cells in connective tissue, respond to mechanical stretching. In this ex vivo study, they stretched samples of subcutaneous tissue for 30 minutes and observed change…
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