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63 results for "inflammation"

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30

2022
Title match
Piezo1 Channels as Force Sensors in Mechanical Force-Related Chronic Inflammation
Hailin Liu, Jialing Hu, Qingcui Zheng, Xiaojin Feng, Fenfang Zhan, Xifeng Wang, Guohai Xu, Fuzhou Hua
This narrative review explores the role of Piezo1 ion channels as mechanical sensors that link physical force to chronic inflammation. Piezo1 channels open in response to stimuli like pressure, stretch, and tissue stiff…
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2021
Title match
Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice
Beatriz Carmona-Hidalgo, Isabel González-Mariscal, Adela García-Martín, María E Prados, Francisco Ruiz-Pino, Giovanni Appendino, Manuel Tena-Sempere, Eduardo M…
This study investigated Δ9-tetrahydrocannabinolic acid (Δ9-THCA), the non-psychoactive precursor to THC, for its effects on liver fibrosis and inflammation in mice and cell cultures. The researchers found that Δ9-THCA r…
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2021
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The Molecular Targets of Cannabinoids in the Treatment of Cancer and Inflammation
Alenabi Aylar, Malekinejad Hassan
This narrative review examines how cannabinoids influence inflammation and cancer by interacting with the body's endocannabinoid system. The researchers describe how endogenous, plant-derived, and synthetic compounds ta…
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2020
Title match
Manipulation of the Fascial System Applied During Acute Inflammation of the Connective Tissue of the Thoracolumbar Region Affects Transforming Growth Factor-β1 and Interleukin-4 Levels: Experimental Study in Mice
Maria Elisa Duarte França, Larissa Sinhorim, Daniel Fernandes Martins, Robert Schleip, Nicolas A M M Machado-Pereira, Gabriel Melo de Souza, Verônica Vargas Ho…
This animal study investigated the effects of manual fascial manipulation on acute inflammation in the connective tissue of mice's lower backs. Researchers induced inflammation and then applied a specific manipulation p…
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2020
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Effects of vitamin C on oxidative stress, inflammation, muscle soreness, and strength following acute exercise: meta-analyses of randomized clinical trials
Natiele Camponogara Righi, Felipe Barreto Schuch, Angélica Trevisan De Nardi, Caroline Montagner Pippi, Geovana de Almeida Righi, Gustavo Orione Puntel, Antoni…
This meta-analysis compiled results from 18 randomized clinical trials to investigate the effects of vitamin C supplementation following a single bout of exercise. The researchers found that vitamin C reduced certain ma…
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2019
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Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury
Enrico Sangiovanni, Marco Fumagalli, Barbara Pacchetti, Stefano Piazza, Andrea Magnavacca, Saba Khalilpour, Gloria Melzi, Giulia Martinelli, Mario Dell'Agli
This in vitro study investigated how Cannabis sativa extract and its component cannabidiol (CBD) affect inflammation in human skin cells. Researchers found that both the extract and pure CBD reduced the release of sever…
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2019
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Hyaluronan: molecular size-dependent signaling and biological functions in inflammation and cancer
Anastasia G Tavianatou, Ilaria Caon, Marco Franchi, Zoi Piperigkou, Devis Galesso, Nikos K Karamanos
This narrative review explores how hyaluronan (HA), a key component of the extracellular matrix, functions differently depending on its molecular size. Large, high-molecular weight HA has different biological properties…
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2019
Title match
Distinct fibroblast subsets drive inflammation and damage in arthritis
Adam P Croft, Joana Campos, Kathrin Jansen, Jason D Turner, Jennifer Marshall, Moustafa Attar, Loriane Savary, Corinna Wehmeyer, Amy J Naylor, Samuel Kemble, J…
This study in mice investigated the role of fibroblasts, a type of connective tissue cell, in arthritis. Researchers identified two distinct subsets of fibroblasts with different functions. One type, located in the syno…
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