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59 results for "extracellular matrix"

Research

30

2019
Title match
Extracellular matrix composition of connective tissues: a systematic review and meta-analysis
Turney J McKee, George Perlman, Martin Morris, Svetlana V Komarova
This systematic review and meta-analysis compiled data to quantify the protein composition of the extracellular matrix (ECM) in various human connective tissues. Researchers analyzed data from studies on bone, adipose t…
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2020
Title match
Alterations of Extracellular Matrix Mechanical Properties Contribute to Age-Related Functional Impairment of Human Skeletal Muscles
Piero Pavan, Elena Monti, Michela Bondí, Chenglei Fan, Carla Stecco, Marco Narici, Carlo Reggiani, Lorenzo Marcucci
This study investigated why muscles become stiffer with age by comparing individual muscle fibers to bundles of fibers that include the extracellular matrix (ECM). Researchers found that while the stiffness of individua…
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2023
Title match
Functional organization of extracellular hyaluronan, CD44 and RHAMM
Mary K Cowman, Eva A Turley
In this comprehensive review, the authors explore how hyaluronan (HA) and its receptors, CD44 and RHAMM, organize the space immediately surrounding cells. In healthy tissue, these components maintain a stable environmen…
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2022
Title match
Evidence of Renin-Angiotensin System Receptors in Deep Fascia: A Role in Extracellular Matrix Remodeling and Fibrogenesis?
Carmelo Pirri, Brasilina Caroccia, Andrea Angelini, Lucia Petrelli, Maria Piazza, Carlo Biz, Pietro Ruggieri, Raffaele De Caro, Carla Stecco
This study investigated the presence of renin-angiotensin system (RAS) components in the deep fascia, specifically the thoracolumbar fascia of the lower back. Researchers found that receptors for angiotensin II, particu…
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2021
Topic match
Hyaluronan and the Fascial Frontier
Rebecca L Pratt
This narrative review explores the role of hyaluronan (HA) in the body's fascial system. HA is a key component of the extracellular matrix, widely used in products from skin creams to joint injections for its ability to…
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2021
Topic match
A Closer Look at the Cellular and Molecular Components of the Deep/Muscular Fasciae
Caterina Fede, Carmelo Pirri, Chenglei Fan, Lucia Petrelli, Diego Guidolin, Raffaele De Caro, Carla Stecco
This narrative review describes fascia as a complex and dynamic connective tissue network. This network is composed of different cell types, an extracellular matrix, and nerve fibers. Each component plays a specific rol…
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2022
Title match
H2 Inhibits the Formation of Neutrophil Extracellular Traps
Kohsuke Shirakawa, Eiji Kobayashi, Genki Ichihara, Hiroki Kitakata, Yoshinori Katsumata, Kazuhisa Sugai, Yoji Hakamata, Motoaki Sano
This study investigates how molecular hydrogen (H2) may inhibit the formation of neutrophil extracellular traps (NETs), which are web-like DNA structures released by the immune system. While NETs help fight infections,…
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2020
Topic match
Feeling Things Out: Bidirectional Signaling of the Cell–ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation
Andrew E Miller, Ping Hu, Thomas H Barker
This narrative review describes how cells and their surrounding environment, the extracellular matrix (ECM), constantly communicate with each other. This communication involves physical cues from the ECM being translate…
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