59 results for "extracellular matrix"
Research
- 2021Content match
Vascular Stiffness in Aging and Disease
Stephen F Vatner, Jie Zhang, Christina Vyzas, Kalee Mishra, Robert M Graham, Dorothy E Vatner
This narrative review examines how vascular stiffness, particularly in the aorta, increases with age and contributes to various cardiovascular diseases. Research suggests that stiffness often progresses more significant…
A+ - 2020Content match
Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial Tissue
Caterina Fede , Carmelo Pirri , Lucia Petrelli, Diego Guidolin , Chenglei Fan, Raffaele De Caro, Carla Stecco
This laboratory study investigated how fascial cells respond to cannabinoids. Researchers isolated fibroblast cells from human fascia lata and treated them with a substance that activates cannabinoid receptor 2. The tre…
A++ - 2019Content match
Hierarchical Hydrogel Composite Interfaces with Robust Mechanical Properties for Biomedical Applications
Yuting Zhu, Qiang Zhang, Xiaoli Shi, Dong Han
This review summarizes advances in hydrogel composites, materials designed to mimic the body's extracellular matrix (ECM). Cells naturally sense and respond to the mechanical properties and physical structure of the ECM…
A - 2019Content match
Hyaluronan fragments produced during tissue injury: A signal amplifying the inflammatory response
Angela Avenoso, Giuseppe Bruschetta, Angela D'Ascola, Michele Scuruchi, Giuseppe Mandraffino, Rosa Gullace, Antonino Saitta, Salvatore Campo, Giuseppe M Campo
This narrative review examines how fragments of hyaluronan (HA), a major component of the extracellular matrix, contribute to inflammation. During tissue injury, large HA molecules are broken down into smaller pieces. E…
B - 2019Content match
Tissue Regeneration from Mechanical Stretching of Cell–Cell Adhesion
Amir Monemian Esfahani, Jordan Rosenbohm, Keerthana Reddy, Xiaowei Jin, Tasneem Bouzid, Brandon Riehl, Eunju Kim, Jung Yul Lim, Ruiguo Yang
This narrative review explores how mechanical stretching can stimulate tissue regeneration and wound healing. Researchers have long known that cells respond to mechanical forces, but much of the focus has been on the co…
A - 2019Content match
Hyaluronan: molecular size-dependent signaling and biological functions in inflammation and cancer
Anastasia G Tavianatou, Ilaria Caon, Marco Franchi, Zoi Piperigkou, Devis Galesso, Nikos K Karamanos
This narrative review explores how hyaluronan (HA), a key component of the extracellular matrix, functions differently depending on its molecular size. Large, high-molecular weight HA has different biological properties…
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