Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
- A2018
Neuroinflammation and central sensitization in chronic and widespread pain
Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William MaixnerChronic pain is partly maintained by central sensitization, a state where the nervous system becomes hypersensitive. This review discusses how neuroinflammation—inflammation in the nervous system—contributes to this pro…
inflammationchronic paainneuroinflammationsensitization - A2018
Morphological evidence of telocytes in human synovium
Irene Rosa, Mirca Marini, Daniele Guasti, Lidia Ibba-Manneschi, Mirko ManettiA relatively new type of cell, called a telocyte, has been found in many human tissues. This study was the first to look for and find these cells in the synovial membrane, which is the lining of our movable joints. Usin…
telocytessynovium - A2018
The anatomical relationships of the tongue with the body system
Bruno Bordoni, Bruno Morabito, Roberto Mitrano, Marta Simonelli, Anastasia ToccafondiIn this review article, the authors examine the tongue's functions and its anatomical connections to the rest of the body. The tongue is not only essential for swallowing, breathing, and speaking, but it also affects po…
fasciadiaphragmphysiotherapytonguespeech therapy - A+++2018
The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
Tarek Mazzawi, Gülen Arslan Lied, Dag André Sangnes, Magdy El-Salhy, Johannes R Hov, Odd Helge Gilja, Jan Gunnar Hatleb…This clinical study investigated how fecal microbiota transplantation (FMT) affects gut bacteria and symptoms in patients with irritable bowel syndrome (IBS). Thirteen patients received stool from healthy donors via gas…
irritable bowel syndromeIBSFecal microbiota transplantation - B2017
Sensitivity of ACL Volume and T2* Relaxation Time to Magnetic Resonance Imaging Scan Conditions
Jillian E Beveridge, Edward G Walsh, Martha M Murray, C FlemingThis animal study investigated how different magnetic resonance imaging (MRI) conditions affect measurements of the anterior cruciate ligament (ACL). Researchers in this pig study compared images taken at different reso…
ACL; MRI; T2* relaxometry - C2017
Hypermobile Ehlers–Danlos Syndrome (a.k.a. Ehlers–Danlos Syndrome Type III and Ehlers–Danlos Syndrome Hypermobility Type): Clinical Description and Natural History
Brad Tinkle, Marco Castori, Britta Berglund, Helen Cohen, Rodney Grahame, Hanadi Kazkaz, Howard LevyThis 2017 review summarizes the clinical understanding of hypermobile Ehlers-Danlos syndrome (hEDS), thought to be the most common hereditary disorder of connective tissue. It is primarily characterized by musculoskelet…
joint hypermobilityjoint hypermobility syndromeEhlers–Danlos syndrome type IIEhlers–Danlos syndrome hypermobility type - A2017
Don’t Forget the Abdominal Wall: Imaging Spectrum of Abdominal Wall Injuries after Nonpenetrating Trauma
Shanna A Matalon, Reza Askari, Jonathan D Gates, Ketan Patel, Aaron D Sodickson, Bharti KhuranaAbdominal wall injuries from non-penetrating trauma are relatively common but are often overlooked in the emergency department. This can happen because more severe, distracting injuries draw attention away, or because t…
abdominal wallabdominal wall injuriesabdominal wall herniaabdominal wall muscle injurycostochondral rib injury - B2017
Mechanical Properties of the Cytoskeleton and Cells
A F Pegoraro, P Janmey, D A WeitzIn this review article, the authors describe the cytoskeleton, which is the cell's main mechanical structure. It is a complex and dynamic network of biopolymers that includes microtubules, actin, and intermediate filame…
cytoskeletonmicrotubulesactin filamentintermediate filament - A2017
CT arthrography of adhesive capsulitis of the shoulder: Are MR signs applicable?
Milena Cernya, Patrick Omoumia, Ahmed Larbi, Daniel Manicourt, Anne Perozziello, Frédéric Lecouvet, Bruno Vande Berg, B…This retrospective study investigated whether signs of adhesive capsulitis (frozen shoulder) typically seen on MRI could also be identified using CT arthrography (CTA). Researchers compared CTA scans from 22 patients wi…
frozen shoulderAdhesive capsulitisArthrographyRotator intervalCTA - C2017
Concurrent validity of pain scales in individuals with myofascial pain and fibromyalgia
Scott W Cheatham, Morey J Kolber, Monique Mokha, William J HanneyResearchers investigated the reliability of two common tools for measuring pain: the Numeric Pain Rating Scale (NPRS), where patients rate pain from 0 to 10, and the Visual Analog Scale (VAS). The study included 60 part…
Myofascial painFibromyalgiapain scales - A+2017
Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
A W Ashor, A D Werner, J Lara, N D Willis, J C Mathers, M SiervoThis systematic review and meta-analysis compiled data from 22 randomized controlled trials to assess the effect of vitamin C supplementation on glycemic control. Overall, the researchers found no significant effect on…
Vitamin Cinsulin resistensglycaemic control - A+++2017
Role of Magnesium in Vitamin D Activation and Function
Anne Marie Uwitonze, Mohammed S RazzaqueIn this scientific review, the authors discuss how magnesium and vitamin D work together in the body. Magnesium acts as a cofactor, meaning it helps activate the enzymes that metabolize vitamin D in the liver and kidney…
Vitamin D activationmagnesiumcalcidefiolcalcitriol - A+++2017
Shielding of the geomagnetic field reduces hydrogen peroxide production in human neuroblastoma cell and inhibits the activity of CuZn superoxide dismutase
Hai-Tao Zhang, Zi-Jian Zhang, Wei-Chuan Mo, Ping-Dong Hu, Hai-Min Ding, Ying Liu, Qian Hua, Rong-Qiao HeThis study investigates how an extremely weak magnetic field, similar to conditions in outer space or shielded environments on Earth, affects human cells. Researchers found that shielding the natural geomagnetic field r…
hydrogen peroxide; hypomagnetic field; oxidative stress; reactive oxygen species; superoxide dismutase - A2017
Amino acid composition in determination of collagen origin and assessment of physical factors effects
Marlena Gauza-Włodarczyk, Leszek Kubisz, Dariusz WłodarczykThis study examines the amino acid composition of collagen derived from various sources, including fish skin, bovine Achilles tendon, and bone tissue. The researchers found that the levels of hydroxyproline, a unique am…
hydroxyprolineBone collagenFish skin collagenIrradiationPolymer - A+2017
The nature and biology of basement membranes
Ambra Pozzi, Peter D Yurchenco, Renato V IozzoThis review article discusses the nature and biology of basement membranes. These are thin, flexible sheets of tissue that line and separate different structures in the body. Once thought to be just passive scaffolding,…
Collagen; laminin; heparan sulfate proteoglycan; discoidin domain receptor; integrin - A2017
Non-contrast MRI diagnosis of adhesive capsulitis of the shoulder
Andrew S Chi, John Kim, Suzanne S Long, William B Morrison, Adam C ZogaThis study investigated whether a standard MRI without contrast dye could be used to reliably diagnose adhesive capsulitis, also known as frozen shoulder. Researchers reviewed MRIs for specific signs, such as a thickene…
MRIfrozen shoulderAdhesive capsulitisNoncontrast - B2017
Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells
Masahiro Ohgidani, Takahiro A Kato, Masako Hosoi, Makoto Tsuda, Kohei Hayakawa, Chie Hayaki, Rie Iwaki, Noriaki Sagata,…Researchers are investigating the role of brain immune cells called microglia in fibromyalgia. This study used a new technique to create microglia-like cells from the blood of people with fibromyalgia and healthy indivi…
Fibromyalgiamikroglia - A2017
Correlations of magnetic resonance imaging findings with clinical symptom severity and prognosis of frozen shoulder
Jong Pil Yoon, Seok Won Chung, Byung Joo Lee, Hyung Sup Kim, Jae Hyuck Yi, Hyun‑Joo Lee, Won‑Ju Jeong, Sung Gyu Moon, K…Researchers used a specific type of MRI (indirect MR arthrography) to examine the shoulders of 52 people with frozen shoulder and 52 without. They found that certain features, like thickening and inflammation-related ch…
frozen shoulderMR findingIndirect MR arthrogramClinical symptomCorrelation - A2017
Adhesive Capsulitis of the Shoulder Joint: Value of Glenohumeral Distance on Magnetic Resonance Arthrography
Kyu Hong Lee, Hee Jin Park, So Yeon Lee, In Young Youn, Eugene Kim, Jai Hyung Park, Se Jin ParkResearchers investigated a new way to help diagnose adhesive capsulitis (frozen shoulder) using a specific type of MRI called MR arthrography. They measured the distance between the ball and socket of the shoulder joint…
Adhesive capsulitisMR imagingShoulderArthrography - B2017
Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma
Emmanuel Bäckryd, Lars Tanum, Anne-Li Lind, Anders Larsson, Torsten GordhThis study investigated signs of inflammation in people with fibromyalgia (FM). Researchers analyzed 92 different inflammation-related proteins in both blood plasma and cerebrospinal fluid from 40 FM patients, comparing…
inflammationFibromyalgiacytokineschronic paincerebrospinal fluid - A+2017
The Effect of Menstrual Cycle and Contraceptives on ACL Injuries and Laxity
Simone D Herzberg, Makalapua L Motu’apuaka, William Lambert, Rongwei Fu, Jacqueline Brady, Jeanne-Marie GuiseThis systematic review and meta-analysis investigated the relationship between the menstrual cycle, hormonal contraceptives, and the risk of anterior cruciate ligament (ACL) injuries. The researchers found that knee lig…
anterior cruciate ligament; knee injury; hormonal contraceptives; female; human; menstrual cycle; systematic review; meta-analysis; sports medicine - A2017
Human mesenchymal stem cells secrete hyaluronan-coated extracellular vesicles
Uma Thanigai Arasu, Riikka Kärnä, Kai Härkönen, Sanna Oikari, Arto Koistinen, Heikki Kröger, Chengjuan Qu, Mikko J Lamm…Mesenchymal stem cells (MSCs) are known to help with tissue repair, partly by releasing tiny packages called extracellular vesicles (EVs). This study investigated the connection between these EVs and hyaluronan (HA), a…
Hyaluronan; CD44; Extracellular vesicle; Stem cell; Filopodia; Hyaluronan synthase - A+++2017
The deep fascia and retinacula of the equine forelimb - structure and innervation
Aleksandra Skalec, Monika EgerbacherThis study investigated the deep fascia and its reinforcements (retinacula) in the equine forelimb using anatomical dissection and microscopic analysis. The researchers found that horse fascia is structurally similar to…
equine; fascia; forelimb; innervation; retinaculum; structure - B2017
The Application of Acoustic Myography in Canine Muscle Function and Performance Testing
Christina Fenger, Adrian P HarrisonThis animal study on 11 Labrador dogs used acoustic myography (AMG) to measure muscle activity during walking and trotting. Researchers focused on two muscles, the m. gluteus superficialis and m. longissimus lumborum, t…
Mechanomyographym.longissimusm.glutealDogMuscle contraction - A2017
Does the vaginal wall become thinner as prolapse grade increases?
Rhiannon Bray, Alex Derpapas, Ruwan Fernando, Vik Khullar, Demetri C PanayiThis study investigated the relationship between vaginal wall thickness and the severity of pelvic organ prolapse. Researchers used ultrasound to measure the vaginal walls of 243 women with symptomatic prolapse. They fo…
Prolapse . Ultrasonography . Vaginal wall thickness - A+++2017
Early versus Delayed Rehabilitation after Acute Muscle Injury
Monika L Bayer, Peter Magnusson, Michael KjaerThis research entry, titled "Early versus Delayed Rehabilitation after Acute Muscle Injury," is currently awaiting a detailed summary. The title suggests it explores the optimal timing for starting rehabilitation follow…
Rehabilitationmuscle injurymechanical loading in rehabilitation - A++2017
The effect of pre-exercise vibration stimulation on the exercise-induced muscle damage
Ji-Yun Kim, Da-Haeng Kang, Joon-Hee Lee, Se-Min O, Jae-Keun JeonThis study investigated whether vibration stimulation before or after exercise could reduce exercise-induced muscle damage. Thirty healthy men were divided into three groups: one receiving vibration before exercise, one…
pressure pain thresholdmuscle fatiguemuscle damage - A++2017
EFFECT OF MATRIX RHYTHM THERAPY (MRT) COMBINED WITH PHYSIOTHERAPY INTERVENTION IN FROZEN SHOULDER – A CASE REPORT
Vijay Bhartiya, Shrikant Darade, Sandip Bhagwat, Manjumala RoyThis case report describes the treatment of a 52-year-old man with a painful and stiff right shoulder, diagnosed as frozen shoulder. His condition also involved tendinosis, bursitis, and osteoarthritic changes. The pati…
exercisesfrozen shoulderMRT - A+++2017
Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats
Victor Fabricio, Jorge Camargo Oishi, Bruna Gabriele Biffe, Leandro Dias Gonçalves Ruffoni, Karina Ana da Silva, Keico…This animal study on rats investigated how resveratrol affects blood pressure and vascular function during estrogen deficiency, mimicking post-menopausal conditions. Researchers found that a lack of estrogen led to high…
blood pressureresveratrolPostmenopause - A+++2017
Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study
John F Pearson, Juliet M Pullar, Renee Wilson, Janet K Spittlehouse, Margreet C M Vissers, Paula M L Skidmore, Jinny Wi…This cohort study examined vitamin C status in 404 fifty-year-olds in New Zealand. Researchers measured the concentration of vitamin C in participants' blood plasma as well as their dietary intake. The results showed th…
ascorbate; cognition; HbA1c; insulin; glucose; hypovitaminosis C - 1A+2017
Emotions in Motion: Myofascial Interoception
B Bordoni, F MarelliIn this perspective piece, the authors argue that the myofascial system is closely linked to our emotional state. They suggest that manual treatment not only affects the body physically but also activates the interocept…
fasciaManual TherapyMyofascialOsteopathicInteroception - A+++2017
Resveratrol regulates body weight in healthy and ovariectomized rats
Rupali Sharma, Neel Kamal Sharma, M ThungapathraThis animal study on rats investigated how the plant compound resveratrol affects body weight in both healthy subjects and those who had undergone ovariectomy, a model for menopause. The results suggest that resveratrol…
OVX; Ovariectomy; Resveratrol; Soya free diet - A2017
The second terminations of the suboccipital muscles: An assistant pivot for the To Be Named Ligament
Xiao-Ying Yuan, Chan Li, Jia-Ying Sui, Qi-Qi Zhao, Xiao Zhang, Na-Na Mou, Zhao Huang-Fu, Okoye Chukwuemeka Samuel, Nan…In this anatomical dissection study of 35 head-neck specimens, researchers investigated small muscle attachments in the suboccipital region. The scientists confirmed the existence of "second terminations" from several s…
Myodural Bridge - A2017
The universal existence of myodural bridge in mammals: an indication of a necessary function
Nan Zheng, Xiao-Ying Yuan, Yan-Yan Chi, Pei Liu, Bing Wang, Jia-Ying Sui, Seung-Ho Han, Sheng-Bo Yu, Hong-Jin SuiThe myodural bridge is a connective tissue structure linking one of the deep, upper neck muscles to the spinal dura mater. This anatomical study investigated whether this structure, known in humans, also exists in other…
Myodural Bridge - A+++2017
Resveratrol supplementation reduces pain experience by postmenopausal women
Rachel H X Wong, Hamish M Evans, Peter R C HoweThis randomized, double-blind, placebo-controlled study investigated whether resveratrol supplementation could reduce pain and improve well-being in postmenopausal women. Over 14 weeks, participants taking 75 mg of resv…
Resveratrolpolyphenolemenopause - A+++2017
Proinflammatory Cytokines and Oxidative Stress Decrease the Transport of Dopamine Precursor Tyrosine in Human Fibroblasts
Ravi Vumma, Jessica Johansson, Nikolaos VenizelosThis laboratory study investigated how inflammation and oxidative stress affect the transport of the amino acid tyrosine in human fibroblasts, a type of connective tissue cell. Tyrosine is a crucial precursor for the ne…
Dopamine precursor; Human fibroblasts; Neuropsychiatric disorders; Oxidative stress; Proinflammatory cytokines; Tyrosine transport. - B2017
Mechanical properties of a collagen fibril under simulated degradation
David C Malaspinaa, Igal Szleifera, Yasin DhaheraThis study used computer simulations to investigate how collagen fibrils lose their strength. Researchers modeled three different types of degradation: the removal of cross-links, surface damage, and damage throughout t…
collagenMolecular dynamicsDegradationMMP - A2017
The myodural bridge existing in the Nephocaena phocaenoides
Pei Liu, Chan Li, Nan Zheng, Qiang Xu, Sheng-Bo Yu, Hong-Jin SuiThe myodural bridge is a connection between a small neck muscle and the spinal cord's outer covering (the dura mater) previously identified in humans. In this anatomical animal study, researchers investigated whether a…
dura materMyodural Bridge - A2017
Rectus Capitis Posterior Minor
Gabriel Venne, Brian J Rasquinha, Manuela Kunz, Randy E EllisThis cadaver study investigated the connection between a small neck muscle (Rectus Capitis Posterior Minor, RCPMi) and the spinal dura mater. Researchers used both microscopic analysis and biomechanical testing to clari…
biomechanical testingcervical dura matermechanical influence of musclesmechanical influence of soft tissuerectus capitis posterior minor - A+++2017
Therapeutic effectiveness of instrument-assisted soft tissue mobilization for soft tissue injury: mechanisms and practical application
Jooyoung Kim, Dong Jun Sung, Joohyung LeeThis narrative review explores the mechanisms and practical use of Instrument-Assisted Soft Tissue Mobilization (IASTM) for treating soft tissue injuries. IASTM involves using specialized tools to apply mechanical press…
Injury; Instrument-assisted soft tissue mobilization; Pain; Range of motion; Soft tissue function. - A++2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study
Paul E Marik, Vikramjit Khangoora, Racquel Rivera, Michael H Hooper, John CatravasIn this retrospective before-after study, researchers investigated the effect of a combination therapy of intravenous vitamin C, hydrocortisone, and thiamine for patients with severe sepsis and septic shock. They compar…
corticosteroid; hydrocortisone; septic shock; thiamine; vitamin C - A++2017
A New Definition of an Acupuncture Meridian
Fletcher KovichThis perspective article proposes a new definition of acupuncture meridians, moving away from the idea of dedicated anatomical vessels. The author suggests that meridians are actually tracts of tissue that become affect…
acupunctureelectrical wavesemiconductionsignal propagation - A+2017
Theoretical study of aerobic vitamin C loss kinetics during commercial heat preservation and storage
Micha PelegThis theoretical study presents a mathematical model to describe how vitamin C is lost in food during commercial heat processing and storage. The model accounts for the degradation of two forms of the vitamin, ascorbic…
Ascorbic acid; Degradation reactions; Dehydroascorbic acid; Kinetics; Storage; Thermal processing. - A2017
The indeterminable resilience of the fascial system
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice SacconiThis commentary proposes a model of fascia not as layers, but as a network of polyhedral microvacuoles of connective tissue. These structures connect the body's systems and can change shape in response to tension, allow…
fasciafibroblastManual TherapyOsteopathicfascial continuum - A++2017
Interaction between the gut microbiome and mucosal immune system
Na Shi, Na Li, Xinwang Duan, Haitao NiuIn this narrative review, the authors outline the two-way relationship between the gut microbiome and the mucosal immune system. A balanced microbiome is essential for the proper maturation and function of the immune sy…
inflammationMicrobiomeImmunity - A2017
The significance of closed kinematic chains to biological movement and dynamic stability
Stephen Levin, Susan Lowell de Sol!orzano, Graham ScarrBiomechanical research has long focused on the body as a system of levers, but this review highlights the importance of "closed kinematic chains" (CKCs). These are continuous mechanical loops that couple multiple parts…
biotensegrityBiomechanicsClosed-chainDevelopmentEvolution - A+2017
Quantitative tissue parameters of Achilles tendon and plantar fascia in healthy subjects using a handheld myotonometer
Sarah Orner, Wolfgang Kratzer, Julian Schmidberger, Beate GrünerThis study examined the mechanical properties of the Achilles tendon and plantar fascia in over 150 healthy adults using a handheld device called a MyotonPRO. The goal was to establish baseline normal values for tissue…
fasciaachilles tendonplantar fasciaMyotonePRO - A++2017
Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer’s disease and a novel protective role for ascorbate
Shilpy Dixit, Joshua P Fessel, Fiona E HarrisonIn this animal study, researchers examined mitochondrial function in a mouse model of Alzheimer's disease and in mice with low levels of vitamin C (ascorbate). The results indicated that both the presence of amyloid (as…
Alzheimer’s disease; mitochondria; oxidative stress; ascorbate; energy production - A++2017
A Curious Oversight in Acupuncture Research
Fletcher KovichIn this perspective article, the author argues that current acupuncture hypotheses overlook a crucial factor: the speed at which the treatment takes effect. Observations suggest that communication between acupoints and…
acupunctureelectrical wavesemiconductionsignal propagation - B2017
Evaluation of fascial manipulation in carpal tunnel syndrome
Marco Pintucci, Marta Imamura, Aurore Thibaut, Lucas M de Exel Nunes, Mylene Mayumi Nagato, Helena H Kaziyama, Satiko T…Details for this study are not yet available. The research, published in 2017, appears to evaluate the effectiveness of Fascial Manipulation® for treating carpal tunnel syndrome. Without an abstract, further details abo…
Fascial manipulationcarpal tunnel syndrome - B2017
Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis
Hsin-Ying Huang, Ana Rivas-Caicedo, François Renevey, Hélène Cannelle, Elisa Peranzoni, Leonardo Scarpellino, Debbie L…This study investigated how antibody-producing plasma cells are supported within lymph nodes. Researchers identified a specific type of connective tissue cell, a medullary fibroblastic reticular cell (FRC), that forms a…
FRC subsetslymph node medullaextrafollicular B cell differentiationplasma cell survivalhumoral response - C2017
S100A4 in cancer progression and metastasis: A systematic review
Fei Fei, Jie Qu, Mingqing Zhang, Yuwei Li, Shiwu ZhangThis systematic review examines the role of the protein S100A4 in cancer progression and metastasis. S100A4 is involved in the epithelial-mesenchymal transition, a key process that allows cancer cells to spread. The aut…
metastasisS100A4malignant tumorepithelial-mesenchymal transition - B2017
All you need to know about the AIP diet
Lana BurgessThis article reviews the Autoimmune Protocol (AIP) diet, which aims to reduce inflammation and relieve symptoms of autoimmune disorders. The diet is based on the idea that problems with the gut wall, sometimes called 'l…
inflammationAutoimmune protocolautoimmune disease - A2017
Reconnecting the Body in Eastern and Western Medicine
Helene M Langevin, Rosa N SchnyerDetails for this 2017 publication, titled 'Reconnecting the Body in Eastern and Western Medicine' by Helene M. Langevin and Rosa N. Schnyer, have not yet been summarized. The title suggests a discussion comparing and in…
acupunctureTCM - A2017
Muscle strength and stiffness in resistance exercise: Force transmission in tissues
Hans Chaudhry, Bruce Bukiet, Ellen Z Anderson, Jared Burch, Thomas FindleyResearchers used a mathematical model to estimate how forces are transmitted through the quadriceps muscle during isometric resistance exercises. They specifically looked at how knee angle affects muscle stiffness, stre…
Knee muscle strength; Stiffness; Mathematical modeling; Resistance exercise - C2017
X-Rays Effects on Cytoskeleton Mechanics of Healthy and Tumor Cells
Valeria Panzetta, Marta De Menna, Ida Musella, Mariagabriella Pugliese, Maria Quarto, Paolo A. Netti, Sabato FuscoThis study investigated how X-ray radiation affects the internal structure, or cytoskeleton, of both healthy cells and tumor cells in a lab setting. Researchers exposed both cell types to different doses of radiation an…
X-rays; Cytoskeleton; Mechanobiology; Focal Adhesion; Particle Tracking; Microrheology - A2017
Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale
Charles Reilly, Donald E IngberA project that began as an artistic endeavor to create an entertaining short film about fertilization led to the development of a new scientific simulation tool. By integrating physics-based animation software from the…
Tensegritysimulationanimationaxonemedynein - A++2017
Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis
Gregory Shaw, Ann Lee-Barthel, Megan L R Ross, Bing Wang, Keith BaarIn a small study involving eight healthy men, researchers investigated the effect of vitamin C-enriched gelatin supplementation before exercise. Participants who consumed 15 grams of gelatin one hour before a short, int…
Bonetendonexerciseligamentreturn to play - A2017
Calcium Signaling in Interstitial Cells: Focus on Telocytes
Beatrice Mihaela Radu, Adela Banciu, Daniel Dumitru Banciu, Mihai Radu, Dragos Cretoiu, Sanda Maria CretoiuThis narrative review describes current knowledge on calcium signaling in a group of cells called interstitial cells, with a special focus on telocytes. These cells and their calcium signals are important for generating…
telocytesinterstitial cellscalcium signalingCa2+ oscillationspacemaker activity - A2017
Piezoelectric material – A promising approach for bone and cartilage regeneration
Namdev More, Govinda KapusettiThis paper outlines a novel hypothesis for regenerating bone and cartilage, two weight-bearing tissues that are challenging to repair. Current treatments for damage from trauma or diseases like osteoarthritis have signi…
tissue engineeringPiezoelectricityBone regenerationCartilage regeneration